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Tackling elephantiasis neuromatosa presented as filariasis in an adult – A management dilemma: A case report 处理神经瘤象皮病在成人中表现为丝虫病-一个管理困境：一个病例报告

Medical Reports Pub Date : 2025-04-26 DOI: 10.1016/j.hmedic.2025.100221

Kelly Meza , Aurpy Das , Aakash Shah , Aparna Jotwani

引用次数: 0

Children bronchial malignancy anesthesia treatment 小儿支气管恶性肿瘤的麻醉治疗

Medical Reports Pub Date : 2025-04-25 DOI: 10.1016/j.hmedic.2025.100222

Shaojuan Chen , Yanyi Cen , Chao Yang , Dejian Chen

引用次数: 0

Stent misplacement across an esophagogastric anastomotic fistula post-ivor Lewis esophagectomy: A case report Lewis食管切除术后食管胃吻合口瘘支架错位1例报告

Medical Reports Pub Date : 2025-04-25 DOI: 10.1016/j.hmedic.2025.100213

Ihab I. El Hajj , Philippe Attieh , Karam Karam , Elias Fiani , Omar Tabbikha , Moussa Abi Ghanem , Ziad S. El Rassi

{"title":"Stent misplacement across an esophagogastric anastomotic fistula post-ivor Lewis esophagectomy: A case report","authors":"Ihab I. El Hajj , Philippe Attieh , Karam Karam , Elias Fiani , Omar Tabbikha , Moussa Abi Ghanem , Ziad S. El Rassi","doi":"10.1016/j.hmedic.2025.100213","DOIUrl":"10.1016/j.hmedic.2025.100213","url":null,"abstract":"<div><div>Ivor Lewis esophagectomy is surgically demanding technique performed by well experienced surgeons with the main goal is complete resection of cancer and lymph nodes with two important benefits for the patient postoperatively including less respiratory adverse events and less postoperative pain. We describe a case of a 72-year-old male patient with a history of esophageal adenocarcinoma. Patient underwent Ivor Lewis esophagectomy for resection of the cancer that was complicated by esophago-gastric anastomotic fistula and pleural abscess formation requiring endoscopic stent and thoracic drain placement. However, upper gastrointestinal series (UGI) showed widening of the fistula suggesting distal stent perforation into the mediastinum confirmed by gastroscopy and requiring further surgical intervention. Patient underwent liberation of the previous esophago-gastric anastomosis and the esophagus up to the level of the cervical esophagus, and removal of the in-situ stent and transection, followed by colonic interposition 3 weeks after the initial diagnosis of the esophagogastric anastomotic fistula. Patient recovered after a prolonged hospital stay.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100213"},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical Reports Pub Date : 2025-04-25 DOI: 10.1016/j.hmedic.2025.100205

Leslie Kim, Hai-Yen Nguyen, Taegen Senawong, Claudia Wei

引用次数: 0

A case report of purple urine bag syndrome associated with Morganella morganii in an acute care setting 紫色尿袋综合征与莫氏摩根菌在急性护理环境的1例报告

Medical Reports Pub Date : 2025-04-24 DOI: 10.1016/j.hmedic.2025.100225

Sonia Shivde, Sreerag Kapparath, Vyom Buch Keyurkumar, Raghunandan Nadig

{"title":"A case report of purple urine bag syndrome associated with Morganella morganii in an acute care setting","authors":"Sonia Shivde, Sreerag Kapparath, Vyom Buch Keyurkumar, Raghunandan Nadig","doi":"10.1016/j.hmedic.2025.100225","DOIUrl":"10.1016/j.hmedic.2025.100225","url":null,"abstract":"<div><div>Purple urine bag syndrome (PUBS) is a rare but benign clinical condition associated with urinary tract infection (UTI), classically described in geriatric patients with immobility, dementia, prolonged indwelling urinary catheter, chronic kidney disease, and female gender. We describe a case of an elderly gentleman presenting with an acute onset delirium and newly diagnosed Parkinsonism. Two days after catheterization, the urine colour changed to an alarming bright purple. Urine examination was suggestive of significant bacteriuria with alkaline pH and culture showing growth of <em>Morganella morganii</em>. Further incubation showed additional growth of <em>Enterococcus faecalis</em>. Though known as an unusual opportunistic pathogen, <em>M. morganii</em> is associated with both prostatitis and PUBS. Our patient had moderate prostatomegaly, but no history of antibiotic exposure or prior indwelling catheter use. Culture-sensitive antibiotic treatment and changing of urinary catheter along with tube-bag set led to complete recovery of UTI in our patient. This is a rare case of PUBS with an atypical organism in a patient without a prior history of prolonged immobility or long-term indwelling catheter use.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100225"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary splenosis mimicking lung metastases in a breast cancer patient: A diagnostic trap 肺性脾肿大模拟乳腺癌患者的肺转移：一个诊断陷阱

Medical Reports Pub Date : 2025-04-24 DOI: 10.1016/j.hmedic.2025.100223

Seif Haddaoui , Nesrine Mejri , Myriam Saadi , Ahmed Anas Haouari , Ines Baccouche , Haifa Rachdi , Yosra Berrazega

{"title":"Pulmonary splenosis mimicking lung metastases in a breast cancer patient: A diagnostic trap","authors":"Seif Haddaoui , Nesrine Mejri , Myriam Saadi , Ahmed Anas Haouari , Ines Baccouche , Haifa Rachdi , Yosra Berrazega","doi":"10.1016/j.hmedic.2025.100223","DOIUrl":"10.1016/j.hmedic.2025.100223","url":null,"abstract":"<div><h3>Background</h3><div>Pulmonary splenosis (PS) is a benign condition resulting from ectopic implantation of splenic tissue following splenic trauma or splenectomy. It can mimic metastatic disease, posing a significant diagnostic challenge, particularly in oncologic patients. We present a case of PS in a breast cancer patient initially misdiagnosed with lung metastases.</div></div><div><h3>Case presentation</h3><div>A 43-year-old female patient with a history of splenectomy was diagnosed with grade III hormone receptor-positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) invasive ductal carcinoma. Imaging suggested metastatic disease, with lung nodules and left subphrenic lesions. First-line treatment with letrozole and ribociclib was initiated. Subsequent imaging revealed stable disease and doubts about the metastatic nature of the lesions were raised. A history of prior splenic trauma and metabolic imaging consistent with splenosis led to a diagnosis of PS. The patient was reclassified as early-stage breast cancer, underwent right mastectomy with axillary lymph node dissection, and achieved a pathological complete response in the primary tumor.</div></div><div><h3>Conclusion</h3><div>This case highlights the importance of considering PS in differential diagnoses for metastatic-like lesions, particularly in patients with a history of splenic trauma, to prevent misdiagnosis and unnecessary treatment.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100223"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare case of small cell carcinoma of the ovary, hypercalcemic type – Diagnostic and therapeutic challenges 罕见的卵巢小细胞癌，高钙血症型-诊断和治疗的挑战

Medical Reports Pub Date : 2025-04-24 DOI: 10.1016/j.hmedic.2025.100220

Jahnavi Ethakota , Bipneet Singh , Haseeb Khan Tareen , Sakshi Bai , Muhammad Fawad Ashraf , Danesh Kumar , Hafsa Ahmed , Fayyaz Hafsa , Granowicz Eric

{"title":"A rare case of small cell carcinoma of the ovary, hypercalcemic type – Diagnostic and therapeutic challenges","authors":"Jahnavi Ethakota , Bipneet Singh , Haseeb Khan Tareen , Sakshi Bai , Muhammad Fawad Ashraf , Danesh Kumar , Hafsa Ahmed , Fayyaz Hafsa , Granowicz Eric","doi":"10.1016/j.hmedic.2025.100220","DOIUrl":"10.1016/j.hmedic.2025.100220","url":null,"abstract":"<div><div>Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), also known as small cell Müllerian ovarian cancer, is a rare and aggressive cancer that primarily affects young women. It contributes to less than 0.1 % of all ovarian cancers and is associated with hypercalcemia in two-thirds of patients. This case report describes a 40-year-old patient presenting with shortness of breath who was ultimately diagnosed with SCCOHT. Laboratory studies demonstrated hypercalcemia and imaging revealed bilateral pulmonary emboli, a mass in the uterus and left adnexa, and peritoneal carcinomatosis. Biopsy revealed a poorly differentiated carcinoma and genetic testing further revealed SMARCA4 mutations, which are seen in cases of SCCOHT. She also had germline ATM and FANCC heterozygous mutations, there is no clear relation established between these mutations and SCCOHT in the literature so far, it would be interesting to see if these mutations can increase the risk of development of SCCOHT and the role of genetic counseling in such cases. Due to its rarity, there is no standard treatment protocol for SCCOHT. She was started on carboplatin/paclitaxel and was referred to a gynecologic oncologist for possible cytoreductive surgery. Reporting such rare cases not only adds to the existing literature but also highlights the importance of further research and the need for defined management guidelines.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100220"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case report of gallbladder adenomyomatosis and acute gangrenous cholecystitis: A causal or coincidental relationship? 胆囊腺肌瘤病与急性坏疽性胆囊炎1例：因果关系还是巧合关系？

Medical Reports Pub Date : 2025-04-24 DOI: 10.1016/j.hmedic.2025.100227

Amir Omar , Rayane Salameh , Karam Karam , Mahmoud Othman

引用次数: 0

Successful Pregnancy 4 Years After Liver Transplant for Hepatocellular Carcinoma: A Case Report 肝癌肝移植术后4年妊娠成功1例报告

Medical Reports Pub Date : 2025-04-24 DOI: 10.1016/j.hmedic.2025.100209

Soheila Aminimoghaddam , Roghayeh Pourali , Mehrsa Shiasi

{"title":"Successful Pregnancy 4 Years After Liver Transplant for Hepatocellular Carcinoma: A Case Report","authors":"Soheila Aminimoghaddam , Roghayeh Pourali , Mehrsa Shiasi","doi":"10.1016/j.hmedic.2025.100209","DOIUrl":"10.1016/j.hmedic.2025.100209","url":null,"abstract":"<div><h3>Background</h3><div>Hepatocellular carcinoma (HCC) is frequently associated with chronic hepatitis and cirrhosis, most commonly affecting men between the ages of 50 and 67. However, certain histological subtypes, such as fibrolamellar HCC, can occur in younger individuals with no gender predilection. Chronic liver disease often leads to amenorrhea and reduced fertility in young women, but liver transplantation has the potential to restore reproductive function. This case report presents a successful pregnancy following liver transplantation for HCC, contributing to the limited literature on pregnancy outcomes in this patient population.</div></div><div><h3>Case Presentation</h3><div>A 27-year-old woman, gravida 1, with a history of liver transplantation for HCC, presented with a positive pregnancy test. Her liver function remained stable while on immunosuppressive therapy with tacrolimus and everolimus. A multidisciplinary team provided comprehensive care, including regular prenatal monitoring and adjustments to immunosuppressive medications to balance the risk of rejection and fetal health. The patient’s liver function remained stable throughout the pregnancy. Delivery was scheduled at 38 weeks due to fetal growth restriction and borderline amniotic fluid index. Labor induction was attempted, but a cesarean section was performed due to active phase arrest. A healthy infant weighing 2,450 g was delivered, and postpartum follow-up confirmed stable liver function for both mother and child.</div></div><div><h3>Conclusion</h3><div>This case highlights that successful pregnancy is possible in liver transplant recipients with a history of HCC when appropriate medical management is provided. It underscores the importance of a multidisciplinary approach to optimize maternal and neonatal outcomes. Further studies are warranted to establish standardized guidelines for managing pregnancies in this unique patient population.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100209"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Report: Unmasking disseminated tuberculosis: A challenging case of neurological, gastrointestinal manifestations, and deep vein thrombosis in a pediatric patient 病例报告：揭露播散性肺结核：一个具有挑战性的病例，神经系统，胃肠道表现，深静脉血栓形成的儿科患者

Medical Reports Pub Date : 2025-04-24 DOI: 10.1016/j.hmedic.2025.100226

Sushmita Bhattarai , Raghab Adhikary , Sanjit Kumar Shah , Kanchan Duwadi

{"title":"Case Report: Unmasking disseminated tuberculosis: A challenging case of neurological, gastrointestinal manifestations, and deep vein thrombosis in a pediatric patient","authors":"Sushmita Bhattarai , Raghab Adhikary , Sanjit Kumar Shah , Kanchan Duwadi","doi":"10.1016/j.hmedic.2025.100226","DOIUrl":"10.1016/j.hmedic.2025.100226","url":null,"abstract":"<div><div>Disseminated tuberculosis can affect multiple organ systems, including the CNS and gastrointestinal tract, and can be associated with thrombotic complications such as DVT. Early diagnosis is critical to reducing morbidity and mortality. This case report discusses the presentation, diagnostic challenges, management, and the rare occurrence of DVT in a child with disseminated TB. A 10-year-old male presented with a month-long history of fever, difficulty walking, slurred speech, and projectile vomiting. Neurological exam revealed left-sided hemiparesis and a GCS of 15/15. Imaging showed hypodense lesions with a mass effect, and CSF Gene Xpert and RT PCR confirmed tubercular meningitis. He later developed gastrointestinal symptoms, diagnosed as granulomatous colitis. On day 12, ultrasound revealed a right iliac vein thrombus, confirming DVT. He improved clinically and was discharged on ATT with steroids. This case underscores the importance of recognizing the diverse presentations of disseminated TB, particularly in children with a history of exposure. The diagnostic delay may lead to severe complications, necessitating a high index of suspicion for TB in atypical presentations. The link between DVT and disseminated TB emphasizes the importance of monitoring for thrombotic events. Timely diagnosis and management of disseminated TB can significantly impact patient outcomes. This case highlights the need for awareness among healthcare providers to consider TB in differential diagnoses, especially in children presenting with neurological and gastrointestinal symptoms, as well as the potential for thrombotic complications.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100226"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0