Medical ReportsPub Date : 2025-05-01DOI: 10.1016/j.hmedic.2025.100230
Vanisha Pundir , Naveen Kumar Kushwaha , Sri Devi
{"title":"Eosinophilic cholangitis: A benign condition masquerading as biliary malignancy","authors":"Vanisha Pundir , Naveen Kumar Kushwaha , Sri Devi","doi":"10.1016/j.hmedic.2025.100230","DOIUrl":"10.1016/j.hmedic.2025.100230","url":null,"abstract":"<div><div>Eosinophilic cholangitis is a rare, benign condition of the biliary tract that often causes obstructive jaundice and poses a significant diagnostic challenge due to its close resemblance to malignancy. It should be considered when imaging shows a biliary stricture, especially if malignancy cannot be definitively diagnosed preoperatively, alongside peripheral eosinophilia and the absence of typical malignancy symptoms. We present a rare case of a young male with painless obstructive jaundice caused by a biliary stricture in the distal common bile duct, masquerading as biliary malignancy and ultimately diagnosed as idiopathic hypereosinophilic syndrome with eosinophilic cholangitis. The case underscores the diagnostic and therapeutic challenges involved and highlights the importance of a multidisciplinary approach and strict adherence to treatment protocols to achieve a favorable outcome.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100230"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143899104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Single coronary artery anomaly with critical left anterior descending artery stenosis: A case of percutaneous intervention in congenital right coronary artery agenesis","authors":"Ofe Eugene Kwaku , Hao Luo , Cong Wen , Rongchuan Yue","doi":"10.1016/j.hmedic.2025.100229","DOIUrl":"10.1016/j.hmedic.2025.100229","url":null,"abstract":"<div><div>Congenital agenesis of the right coronary artery (RCA) is a rare coronary anomaly that may coexist with atherosclerotic disease and pose unique diagnostic and therapeutic challenges. We present the case of a 60-year-old woman with a 10-year history of hypertension who experienced refractory nocturnal angina despite optimal medical therapy. Coronary computed tomography angiography (CCTA) revealed congenital RCA agenesis and critical (70–80 %) narrowing of the proximal-to-mid left anterior descending artery (LAD). Invasive angiography confirmed a single coronary artery system (L-I type classification) with severe (80–85 %) LAD stenosis. Percutaneous coronary intervention using a drug-eluting stent was performed to resolve symptoms and restore flow. At 6-month follow-up, the patient remained asymptomatic on guideline-directed therapy. This case underscores two critical points: (1) RCA agenesis exacerbates ischemia in atherosclerotic LAD disease by forcing the left coronary system to perfuse an expanded myocardial territory without collateral compensation, and (2) PCI offers targeted revascularization in anatomically complex congenital anomalies. Noninvasive imaging (CCTA) and invasive angiography remain pivotal for delineating the coronary anatomy and guiding intervention.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100229"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143899105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-30DOI: 10.1016/j.hmedic.2025.100218
April K. Oertle , Dileep Kumar Reddy Regalla
{"title":"A stroke of bad luck: HSV-1 encephalitis in the aftermath of a cerebrovascular accident","authors":"April K. Oertle , Dileep Kumar Reddy Regalla","doi":"10.1016/j.hmedic.2025.100218","DOIUrl":"10.1016/j.hmedic.2025.100218","url":null,"abstract":"<div><div>Herpes simplex virus type 1 (HSV-1) encephalitis is a serious and often fatal condition caused by inflammation of the brain parenchyma. We present a case of a 48-year-old male with a complex medical history who presented with symptoms of right arm weakness, dysarthria, and right facial droop suggestive of an acute cerebrovascular accident. His clinical course was marked by persistent fever and altered mental status. Lumbar puncture revealed a diagnosis of HSV-1 encephalitis. This case focuses on a unique situation in which a cerebrovascular accident and HSV-1 encephalitis manifested together. In our case, MRI showed infarcts in the globus pallidus, which goes against HSV-induced infarcts as HSV spares basal ganglia.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100218"},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diffuse leptomeningeal glioneuronal tumor in a 4-year-old child with urinary tract infection: A case report","authors":"Parsa Yousefichaijan , Mahbod Soltani , Ali Rahnama Sisakht , Negar PoorAhmadian , Zahra Tavassoli","doi":"10.1016/j.hmedic.2025.100224","DOIUrl":"10.1016/j.hmedic.2025.100224","url":null,"abstract":"<div><div>Diffuse leptomeningeal glioneuronal tumor (DLGNT) is a rare pediatric neoplasm characterized by diffuse leptomeningeal enhancement. Patients may present with a range of symptoms, including headaches, vomiting, seizures, and signs of increased intracranial pressure, such as hydrocephalus. Most of these tumors show slow progression and are usually managed through surgical resection, radiation therapy, and/or chemotherapy. Tumors located along the neural axis can interfere with the pathways that control bladder storage and voiding mechanisms. As a result, children with central nervous system (CNS) tumors may encounter different levels of bladder dysfunction. This case report describes a 4-year-old girl who was admitted due to dysuria and lower abdominal pain. Her mother reported that she had paraplegia in her lower extremities, which was accompanied by claudication for 2 days. The patient underwent an MRI following confirmation of the DLGNT diagnosis and exclusion of other etiologies, and Our patient underwent surgical resection of the mass 5 days after admission to the hospital. Remarkably, the patient experienced no complications. Follow-up MRI scans were obtained in two stages, 4 months apart, which demonstrated no evidence of contrast enhancement. Furthermore, this case highlights the possible genetic factors involved in the development of DLGNT, underscoring the need for further exploration of the genetic landscape associated with this rare tumor.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100224"},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-26DOI: 10.1016/j.hmedic.2025.100212
Venkata Surabhi Rayal Akepati, Navaudhayam Ranganathan, Anu Agrawal, Raja Shekar C H T, Vikas Yadav
{"title":"Nasal epithelioid hemangioendothelioma - A rare case report and review of literature","authors":"Venkata Surabhi Rayal Akepati, Navaudhayam Ranganathan, Anu Agrawal, Raja Shekar C H T, Vikas Yadav","doi":"10.1016/j.hmedic.2025.100212","DOIUrl":"10.1016/j.hmedic.2025.100212","url":null,"abstract":"<div><h3>Aim</h3><div>To understand the complexities in diagnosing and managing a rare case of Nasal epithelioid hemangioendothelioma, which can be clinically misdiagnosed as benign inflammatory conditions.</div></div><div><h3>Background</h3><div>Epithelioid hemangioendothelioma (EHE) is a rare locally invasive vascular tumor and it is characterized by proliferation of endothelial cells with epithelioid morphology. It is slow growing tumor with borderline malignant potential and has high chances of recurrence. Mostly seen in soft tissues of extremities, lungs and very rarely seen in head and neck. There are very few cases reported of EHE in nasal cavity.</div></div><div><h3>Case Description</h3><div>The present case report describes an unusual case of EHE of nasal cavity in a 37 year old male with 2 months history of nasal mass, obstruction and intermittent epistaxis. Patient underwent wide local excision of tumor and histopathology confirmed the diagnosis.</div></div><div><h3>Conclusion</h3><div>Usually wide local excision is the treatment of choice. Routinely regular follow up is advised. In cases of multiple recurrences and incompletely excised tumors radiation therapy is considered.</div></div><div><h3>Clinical Significance</h3><div>It is an indolent tumor which has potential for recurrence that is known to appear during adult life and unlikely to metastasize.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100212"},"PeriodicalIF":0.0,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-26DOI: 10.1016/j.hmedic.2025.100211
Eljazouli Ali, Drighil Abdenasser
{"title":"Remarkable recovery of a multicomplicated infective endocarditis due to Bartonella henselae a case report","authors":"Eljazouli Ali, Drighil Abdenasser","doi":"10.1016/j.hmedic.2025.100211","DOIUrl":"10.1016/j.hmedic.2025.100211","url":null,"abstract":"<div><h3>Background</h3><div>Culture-negative infective endocarditis poses a substantial challenge in medical practice, accounting for 75 % of infective endocarditis cases in developed countries. This condition stems from diverse causative agents, with Bartonella emerging as the most prevalent culprit. Owing to limited comprehensive studies and established guidelines, the diagnosis of this condition remains intricate and often relies on anecdotal case reports and small series.</div></div><div><h3>Case presentation</h3><div>We present a compelling case of a 60-year-old male patient who presented with severe chest pain, dyspnea, fever, and an array of additional symptoms. The clinical presentation eventually led to a diagnosis of infective endocarditis, which was unveiled through acute coronary syndrome concomitant with nephrotic syndrome, renal failure, and pancytopenia. Despite the initiation of the initial treatment regimen, the patient exhibited an inadequate response. Subsequent investigations revealed an underlying <em>Bartonella henselae</em> infection. Administration of doxycycline elicited notable improvements in both the patient's clinical status and pertinent laboratory parameters.</div></div><div><h3>Conclusion</h3><div>This case underscores the significance of broadening the scope of diagnostic considerations to encompass less common agents such as Bartonella in cases of culture-negative infective endocarditis.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100211"},"PeriodicalIF":0.0,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143883241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-26DOI: 10.1016/j.hmedic.2025.100221
Kelly Meza , Aurpy Das , Aakash Shah , Aparna Jotwani
{"title":"Tackling elephantiasis neuromatosa presented as filariasis in an adult – A management dilemma: A case report","authors":"Kelly Meza , Aurpy Das , Aakash Shah , Aparna Jotwani","doi":"10.1016/j.hmedic.2025.100221","DOIUrl":"10.1016/j.hmedic.2025.100221","url":null,"abstract":"<div><div>Plexiform neurofibroma is a pathognomonic manifestation of Neurofibromatosis type 1 (NF1), a rare autosomal dominant genetic disorder. Elephantiasis Neuromatosa (EN) is an uncommon presentation of plexiform neurofibroma, which leads to severe limb hypertrophy and resembles filariasis. We discuss the diagnostic challenges encountered in identifying EN, in an adult initially misdiagnosed as filariasis for 15 years. NF-1 diagnostic criteria, including characteristic MRI findings, biopsy, and genetic testing were crucial for accurate diagnosis. The patient was treated with trametinib, resulting in significant clinical improvement within one month, highlighting the potential efficacy of MEK inhibition in managing diffuse plexiform neurofibroma. This case highlights the importance of a multidisciplinary approach and prompt diagnosis in managing rare NF1 presentations like EN, addressing treatment complexities, and access challenges.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100221"},"PeriodicalIF":0.0,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143905871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Children bronchial malignancy anesthesia treatment","authors":"Shaojuan Chen , Yanyi Cen , Chao Yang , Dejian Chen","doi":"10.1016/j.hmedic.2025.100222","DOIUrl":"10.1016/j.hmedic.2025.100222","url":null,"abstract":"<div><div>Pediatric airway malignancies are rare conditions. Tracheal resection and reconstruction (TRR) represents an effective therapeutic approach for managing tracheal tumors. This case report details an 8-year-old girl diagnosed with a malignant tumor of the left main bronchus and an associated atrial septal defect. She underwent tumor resection and tracheal reconstruction under general anesthesia, facilitated by the placement of a 5Fr bronchial blocker within a single-lumen endotracheal tube. It is imperative for anesthesiologists to anticipate potential challenges and develop comprehensive airway management strategies prior to surgery. In this case, the described anesthetic technique was implemented safely and successfully, enabling the surgery to proceed without complications.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100222"},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-25DOI: 10.1016/j.hmedic.2025.100213
Ihab I. El Hajj , Philippe Attieh , Karam Karam , Elias Fiani , Omar Tabbikha , Moussa Abi Ghanem , Ziad S. El Rassi
{"title":"Stent misplacement across an esophagogastric anastomotic fistula post-ivor Lewis esophagectomy: A case report","authors":"Ihab I. El Hajj , Philippe Attieh , Karam Karam , Elias Fiani , Omar Tabbikha , Moussa Abi Ghanem , Ziad S. El Rassi","doi":"10.1016/j.hmedic.2025.100213","DOIUrl":"10.1016/j.hmedic.2025.100213","url":null,"abstract":"<div><div>Ivor Lewis esophagectomy is surgically demanding technique performed by well experienced surgeons with the main goal is complete resection of cancer and lymph nodes with two important benefits for the patient postoperatively including less respiratory adverse events and less postoperative pain. We describe a case of a 72-year-old male patient with a history of esophageal adenocarcinoma. Patient underwent Ivor Lewis esophagectomy for resection of the cancer that was complicated by esophago-gastric anastomotic fistula and pleural abscess formation requiring endoscopic stent and thoracic drain placement. However, upper gastrointestinal series (UGI) showed widening of the fistula suggesting distal stent perforation into the mediastinum confirmed by gastroscopy and requiring further surgical intervention. Patient underwent liberation of the previous esophago-gastric anastomosis and the esophagus up to the level of the cervical esophagus, and removal of the in-situ stent and transection, followed by colonic interposition 3 weeks after the initial diagnosis of the esophagogastric anastomotic fistula. Patient recovered after a prolonged hospital stay.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100213"},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-25DOI: 10.1016/j.hmedic.2025.100205
Leslie Kim, Hai-Yen Nguyen, Taegen Senawong, Claudia Wei
{"title":"Protamine-related non-cardiogenic pulmonary edema during routine heparin reversal for cardiopulmonary bypass","authors":"Leslie Kim, Hai-Yen Nguyen, Taegen Senawong, Claudia Wei","doi":"10.1016/j.hmedic.2025.100205","DOIUrl":"10.1016/j.hmedic.2025.100205","url":null,"abstract":"<div><div>A 62-year-old male presented for coronary artery bypass graft (CABG) and aortic valve replacement (AVR). Following initiation of intravenous (IV) protamine for heparin reversal, the patient developed acute pulmonary edema characterized by reduced oxygen saturations and increasing airway pressures necessitating venoarterial extracorporeal membrane oxygenation (VA-ECMO) for lung recovery. This case report discusses the pathophysiology of protamine-related non-cardiogenic pulmonary edema (NCPE) and its comparison to typical protamine reactions. Anesthesiologists must be aware of this potentially life-threatening complication during procedures where protamine is commonly used to reverse the effects of heparin anticoagulation.</div></div><div><h3>Categories</h3><div>Anesthesiology, Cardiac/Thoracic/Vascular Surgery</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100205"},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}