Medical Reports最新文献_第7页

Atraumatic Isolated Peroneal Compartment Syndrome: A Case Report 非外伤性孤立性腓骨筋膜室综合征1例

Medical Reports Pub Date : 2025-05-19 DOI: 10.1016/j.hmedic.2025.100255

Mahmoud Abdullah Elmahy , Isam Sami Moghamis , Amgad M. Elshoeibi , Mohamed Khalaf , Salahuddeen Abdelsalam , Nasser Mehrab Khan , Abdulmoeen Baco

{"title":"Atraumatic Isolated Peroneal Compartment Syndrome: A Case Report","authors":"Mahmoud Abdullah Elmahy , Isam Sami Moghamis , Amgad M. Elshoeibi , Mohamed Khalaf , Salahuddeen Abdelsalam , Nasser Mehrab Khan , Abdulmoeen Baco","doi":"10.1016/j.hmedic.2025.100255","DOIUrl":"10.1016/j.hmedic.2025.100255","url":null,"abstract":"<div><div>Acute compartment syndrome (ACS) is a surgical emergency that is frequently brought on by trauma and is characterized by increased pressure inside a closed osteofascial compartment. However, because of its unusual presentation and absence of acute trauma, atraumatic ACS, especially when isolated to the peroneal compartment, is uncommon and challenging to identify. We describe a case of a 24-year-old man who had no prior history of direct trauma and who presented with atraumatic left leg discomfort and swelling after physical activity. At another hospital, muscle cramps were initially diagnosed, but as symptoms worsened, additional testing was necessary. Physical examination showed a hard lateral compartment, loss of dorsiflexion, and decreased feeling over the dorsum and lateral portions of the foot. Laboratory investigations showed increased creatinine kinase (CK) and myoglobin levels. No bone pathology was visible in the radiographic imaging. Surgical decompression via fasciotomy revealed necrotic peroneal muscles and a hematoma collection. The patient underwent staged debridement and wound management, eventually achieving wound closure and functional recovery with physiotherapy. Six-month follow-up showed restored muscle power. This case emphasizes the importance of considering ACS in atraumatic leg pain and swelling, particularly when CK levels are elevated.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100255"},"PeriodicalIF":0.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144106994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Landau-Kleffner syndrome: A case report Landau-Kleffner综合征1例报告

Medical Reports Pub Date : 2025-05-16 DOI: 10.1016/j.hmedic.2025.100247

Maria Luiza de Andrade , Eugênio Grillo

{"title":"Landau-Kleffner syndrome: A case report","authors":"Maria Luiza de Andrade , Eugênio Grillo","doi":"10.1016/j.hmedic.2025.100247","DOIUrl":"10.1016/j.hmedic.2025.100247","url":null,"abstract":"<div><h3>Objective</h3><div>To contribute to the growing body of literature on Landau-Kleffner syndrome (LKS) by detailing its clinical and imaging features, therapeutic approaches, and clinical outcomes.</div></div><div><h3>Case description</h3><div>5-year-old, female, presented with sleep-related seizures beginning at age 3. At 5, she exhibited psychomotor regression, including loss of drawing skills, language regression, spatial disorientation, and disruptive behaviors such as aggression and attempts to flee. Initial treatment with phenobarbital and oxcarbazepine failed to control seizures. Sleep EEGs revealed a continuous spike-and-wave pattern, and cranial MRI was unremarkable. Based on these findings, LKS was diagnosed. Oxcarbazepine was discontinued, phenobarbital was maintained, and corticosteroid therapy with prednisolone (2 mg/kg/day) was introduced. After one month, she showed significant clinical improvement, including seizure cessation, improved motor function, and partial recovery of cognitive and visuospatial abilities. Subsequent EEGs showed persistent but reduced epileptiform activity. Prednisolone was gradually tapered, and clobazam (20 mg/day) was introduced. She has remained seizure-free for six months, with ongoing speech improvement.</div></div><div><h3>Comments</h3><div>LKS is a rare pediatric neurological disorder characterized by acquired aphasia and epilepsy, often with electrographic abnormalities during sleep. Its etiology is multifactorial, involving genetic, immunologic, and inflammatory mechanisms. Diagnosis relies on clinical history, neurological exam, and sleep EEG. Management includes a combination of pharmacologic therapies (e.g., corticosteroids, antiepileptics, benzodiazepines) and supportive interventions like speech therapy. This case highlights the favorable clinical response to corticosteroids and clobazam in a child with LKS. Informed consent was obtained from the patient’s guardians.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100247"},"PeriodicalIF":0.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144084536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical application of wet healing in the treatment of aplasia cutis congenita on scalp: A case report 湿愈合治疗头皮先天性皮肤发育不全1例

Medical Reports Pub Date : 2025-05-15 DOI: 10.1016/j.hmedic.2025.100251

Guangliang Bi, Abelita P.S.P.M. Ximenes, Weihua Liao, Jing Ding, Jie Yang

{"title":"Clinical application of wet healing in the treatment of aplasia cutis congenita on scalp: A case report","authors":"Guangliang Bi, Abelita P.S.P.M. Ximenes, Weihua Liao, Jing Ding, Jie Yang","doi":"10.1016/j.hmedic.2025.100251","DOIUrl":"10.1016/j.hmedic.2025.100251","url":null,"abstract":"<div><h3>Introduction</h3><div>Aplasia cutis congenita (ACC) is a rare congenital abnormality characterized by localized defects in the skin at birth. It commonly affects the scalp and coexists with cranial bone defects, which increase the risk of infection and bleeding. This risk is particularly heightened for midline lesions. There is currently no clear indication for surgical or conservative treatment, therefore, it would be beneficial to seek scientific support in order to determine the optimal treatment strategies.</div></div><div><h3>Clinical presentation</h3><div>This case report describes a newborn with ACC who had a significant defect measuring 4 cm in diameter, along with cranial bone defects. Following wet and dry healing treatments, the wound healed by the 10th day.</div></div><div><h3>Results</h3><div>The defect showed significant healing within just one week, with the wound progressing from a moist to a dry healing process.</div></div><div><h3>Conclusion</h3><div>The early implementation of moist wound healing therapy along with securing oil gauze with an elastic cap, followed by the application of a dry healing method to expedite crust formation, could possibly serve as the basic wound care therapy for similar ACC cases presenting with cranial defects.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100251"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144106987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pheochromocytoma induced myocardial ischemia: A case report of rare cardiovascular complications 嗜铬细胞瘤致心肌缺血：罕见心血管并发症1例报告

Medical Reports Pub Date : 2025-05-15 DOI: 10.1016/j.hmedic.2025.100245

Z. Shahriar , T. Islam , Md. Amin , A. Zahin

引用次数: 0

Functional convergence spasm in a patient with headache and diplopia: A case report 功能性收敛性痉挛伴头痛复视1例

Medical Reports Pub Date : 2025-05-15 DOI: 10.1016/j.hmedic.2025.100250

Ayesha Zafar , Haroon Ur Rashid , Usman Usman , Muhammad Osama , Abdul Majid , Farhan Shahzad

{"title":"Functional convergence spasm in a patient with headache and diplopia: A case report","authors":"Ayesha Zafar , Haroon Ur Rashid , Usman Usman , Muhammad Osama , Abdul Majid , Farhan Shahzad","doi":"10.1016/j.hmedic.2025.100250","DOIUrl":"10.1016/j.hmedic.2025.100250","url":null,"abstract":"<div><h3>Introduction</h3><div>The convergence spasm is characterized by intermittent episodes of sustained maximal convergence, miosis, and accommodative spasm with associated disconjugate gaze that mimic sixth cranial nerve palsy. Most of these cases are functional<strong>.</strong> We describe a patient with a diagnosis of convergence spasm in a patient experiencing persistent headache and diplopia.</div></div><div><h3>Case presentation</h3><div>A 35-year-old woman came for the assessment of a persistent headache and diplopia. Examination revealed brief episodes (∼10–30 seconds)) of convergent strabismus mimicking sixth cranial nerve palsy. A comprehensive workup including lumbar puncture and MRI scans was initiated. Normal findings prompted holistic management, including Paracetamol, SSRIs, and counseling, resulting in significant clinical improvement within a very short timeframe.</div></div><div><h3>Discussion</h3><div>In order to rule out organic causes, functional disorders such as convergence spasm frequently require thorough studies; however, it is crucial to identify psychosocial stressors. The significance of psychiatric evaluation and early diagnosis of functional etiologies is highlighted by a case, a 28-year-old female with diplopia who improved after being reassured. The same approach improved our patient’s neurological symptoms. A multidisciplinary strategy that combines medical and psychological support works well.</div></div><div><h3>Conclusion</h3><div>This case highlights the complex presentation of convergence spasm, manifesting as persistent headache and diplopia. Clinicians should thoroughly investigate functional etiologies in such cases.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100250"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144070381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating acute leukemia in pregnancy: A case series and clinical insights 妊娠期急性白血病的导航：病例系列和临床见解

Medical Reports Pub Date : 2025-05-14 DOI: 10.1016/j.hmedic.2025.100243

Jahnavi Ethakota , Sudhamalini Parvathareddy , Haseeb Khan Tareen , Devin Malik , Hafsa Ahmed

{"title":"Navigating acute leukemia in pregnancy: A case series and clinical insights","authors":"Jahnavi Ethakota , Sudhamalini Parvathareddy , Haseeb Khan Tareen , Devin Malik , Hafsa Ahmed","doi":"10.1016/j.hmedic.2025.100243","DOIUrl":"10.1016/j.hmedic.2025.100243","url":null,"abstract":"<div><h3>Background/introduction</h3><div>Acute leukemia during pregnancy is exceedingly rare, occurring in fewer than 1 in 100,000 pregnancies. Pregnancy coexisting with malignancy complicates management due to gestational-age–dependent fetal sensitivity to cytotoxic agents and the lack of standardized treatment protocols.</div></div><div><h3>Case presentation</h3><div>We report a series of four pregnant patients diagnosed with acute leukemia at different trimesters. The first-trimester case (12 weeks) elected medical termination prior to induction chemotherapy (3 + 7 daunorubicin/cytarabine → HiDAC consolidation). Three patients in the second and third trimesters (22–29 weeks) received tailored induction and consolidation regimens with biweekly Doppler monitoring, achieving complete maternal remission and favorable neonatal outcomes (deliveries at 31–34 weeks).</div></div><div><h3>Discussion</h3><div>These cases illustrate trimester-specific decision-making: in the first trimester, termination is generally advised before initiating chemotherapy; in later trimesters, anthracycline-based regimens may be safely administered with vigilant fetal surveillance. Risk stratification (WHO criteria, cytogenetics, FLT3-ITD status) and multidisciplinary collaboration are critical to optimize both maternal and fetal prognoses.</div></div><div><h3>Conclusion</h3><div>A structured, trimester-adapted approach to acute leukemia in pregnancy can yield positive outcomes for mother and child. Further prospective studies are needed to refine treatment algorithms, assess novel targeted therapies, and evaluate long-term effects of in utero chemotherapy exposure.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100243"},"PeriodicalIF":0.0,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144290829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative brain abscess of Prevotella Oris due to skull base surgery: Case report and literature review 颅底手术致口普雷沃氏菌术后脑脓肿：病例报告及文献复习

Medical Reports Pub Date : 2025-05-14 DOI: 10.1016/j.hmedic.2025.100249

Shuang-Qi Gao , Jian-Wei Huang , Wen-Han Zheng , Zhen-Dan Zhu, Ying Guo, Hai-Yong He

{"title":"Postoperative brain abscess of Prevotella Oris due to skull base surgery: Case report and literature review","authors":"Shuang-Qi Gao , Jian-Wei Huang , Wen-Han Zheng , Zhen-Dan Zhu, Ying Guo, Hai-Yong He","doi":"10.1016/j.hmedic.2025.100249","DOIUrl":"10.1016/j.hmedic.2025.100249","url":null,"abstract":"<div><h3>Background</h3><div><em>Prevotella Oris</em> is a gram-negative anaerobic bacillus that is rarely encountered in clinical practice. Brain abscesses resulting from this bacterium are exceedingly uncommon, however the advent of skull base surgery has facilitated intracranial infections caused by this bacterium. The challenging conditions of anaerobic bacterial cultures make it difficult to accurately discover the causing pathogen. However, this can be achieved by the use of metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF).</div></div><div><h3>Case presentation</h3><div>In this case study, we present the case of a 29-year-old male who experienced the development of a brain abscess and hydrocephalus as a result of an intracranial infection caused by the genus <em>Prevotella Oris</em> following skull base surgery. The patient's treatment was guided by the findings of a metagenomic test, and the patient's condition showed improvement after a period of two months.</div></div><div><h3>Conclusions</h3><div>Postoperative infections following skull base surgery are extremely uncommon, and specifically, there have been no known cases of brain abscesses caused by <em>Prevotella Oris</em>. This report presents the first documented case of <em>Prevotella Oris</em>. infection resulting from skull base surgery, highlighting the significance of preoperative prophylactic measures and the application of mNGS. This highlights the significance of preoperative prophylaxis and the use of mNGS.</div></div><div><h3>Discussion</h3><div>The mechanism of <em>Prevotella oris</em> infection and resistant. The potential diagnostic value and applications of mNGS.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100249"},"PeriodicalIF":0.0,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143948045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Menorrhagia as an initial presentation of metastatic malignant melanoma: Case report 月经过多作为转移性恶性黑色素瘤的初始表现：病例报告

Medical Reports Pub Date : 2025-05-13 DOI: 10.1016/j.hmedic.2025.100244

Sarah A. Jaggernauth , Dean E. Watkins , Shreya Bhoopathi , Makenna Schroeder , Andrew L. Waack , Jacqueline Boyle , William Miller

引用次数: 0

Stiff Person Syndrome with multisystem complications: A case report and literature review on recent advances in treatment and management

Medical Reports Pub Date : 2025-05-13 DOI: 10.1016/j.hmedic.2025.100248

Aurpy Das , Chowdhury Shakhawat Jahan , Mohammad Monwar Husain

引用次数: 0

Brunner’s gland hamartoma in worsening GERD: A rare case report 恶性胃食管反流并发布伦纳腺错构瘤1例

Medical Reports Pub Date : 2025-05-12 DOI: 10.1016/j.hmedic.2025.100246

Antonio Al Hazzouri , Bassem Derbas , Philippe Attieh , Karam Karam , Elias Fiani

{"title":"Brunner’s gland hamartoma in worsening GERD: A rare case report","authors":"Antonio Al Hazzouri , Bassem Derbas , Philippe Attieh , Karam Karam , Elias Fiani","doi":"10.1016/j.hmedic.2025.100246","DOIUrl":"10.1016/j.hmedic.2025.100246","url":null,"abstract":"<div><h3>Background</h3><div>Brunner’s gland hamartoma is an uncommon, benign duodenal tumor that arises from the Brunner’s glands. It is classified as hyperplasia or hamartoma based on its size. Symptoms include dyspepsia, nausea or postprandial epigastric pain, anemia, gastrointestinal bleed and small bowel obstruction. Its definitive diagnosis is by histopathological findings. We report an unusual case of Brunner’s gland hamartoma presenting as worsening epigastric pain and reflux in a patient with chronic controlled gastroesophageal reflux disease.</div></div><div><h3>Case presentation</h3><div>A 48-years-old female with a history of chronic gastroesophageal reflux disease of 15 years duration on omeprazole, and stage A esophagitis of 4 years duration, presented for worsening epigastric pain and reflux for the past 6 months, with frequent regurgitation of acidic fluid, and postprandial nausea but no vomiting. Esophagogastroduodenoscopy was performed and revealed the presence of a large duodenal polyp. Pathology results were suggestive of Brunner’s gland hamartoma.</div></div><div><h3>Conclusion</h3><div>This article reports a case of Brunner’s gland hamartoma, that is exacerbating a previously controlled gastroesophageal reflux disease, and found incidentally on esophagogastroduodenoscopy. This report highlights the masking of Brunner’s hamartoma by chronic gastroesophageal reflux disease. It also raises awareness of considering this condition as a differential diagnosis in patient with long standing reflux disease that worsens with time.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100246"},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143937110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0