Medical ReportsPub Date : 2025-04-24DOI: 10.1016/j.hmedic.2025.100228
Marco Nezzo , Beatrice Carreri , Matteo Madonna , Daniele Morosetti , Renato Argirò , Valerio Da Ros , Federico Sabuzi , Francesco Garaci
{"title":"Endovascular Glubran 2 and coiling embolization of a pulmonary artery pseudoaneurysm: A case report","authors":"Marco Nezzo , Beatrice Carreri , Matteo Madonna , Daniele Morosetti , Renato Argirò , Valerio Da Ros , Federico Sabuzi , Francesco Garaci","doi":"10.1016/j.hmedic.2025.100228","DOIUrl":"10.1016/j.hmedic.2025.100228","url":null,"abstract":"<div><div>Pulmonary artery pseudoaneurysm (PAP) is a rare but potentially life-threatening condition that necessitates prompt diagnosis and intervention. PAP is commonly associated with hemoptysis, which, when massive (>300 ml/day), carries a 50 % mortality rate. We present the case of a 63-year-old male with a history of chronic obstructive pulmonary disease (COPD) associated with recent episodes of pneumonia, tobacco use and hypertension who was admitted to the emergency department with high fever, productive cough, dyspnea, chest pain and hypoxia with subsequent development of hemoptysis. An urgent chest CT angiogram (CTA) revealed a 15-by-17 mm central enhancing area arising from the right pulmonary artery in the upper-to-mid right lobe within a cavitating pneumonitis parenchymal lung consolidation, compatible with a pulmonary artery pseudoaneurysm. The patient underwent successful endovascular embolization using Glubran 2 and metallic coils. Post-procedural imaging confirmed complete occlusion of the pseudoaneurysm, with no residual flow and resolution of hemoptysis.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100228"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From darkness to light: A child`s battle for the sight–A rare case report with review of literature","authors":"Ankur Vivek, Arpan Mitra, Akansha Jain, Nayana Bhuyan, Vijaya Nath Mishra, Abhishek Pathak","doi":"10.1016/j.hmedic.2025.100216","DOIUrl":"10.1016/j.hmedic.2025.100216","url":null,"abstract":"<div><div>Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological entity marked by distinctive clinical features and corroborated by Magnetic Resonance Imaging. Despite its alarming presentation, PRES is often reversible with appropriate management, showing favourable radiographic and clinical outcomes. Scorpion bite leading to PRES is a rare clinical presentation. Here we have described a case of 4 year old girl with a history of scorpion bite presented with headache, vomiting and seizure with altered sensorium. Based on imaging findings and excluding all other possible causes, diagnosis of PRES was considered. With appropriate treatment there was significant improvement in her symptoms. This is the first case reported from Asia, and it aligns with previous documented reports indicating the potential for scorpion bite to induce PRES. In the context of scorpion stings, PRES is hypothesized to result from a catecholamine surge causing endothelial dysfunction, blood-brain barrier disruption, and autonomic dysregulation. This case underscores the potential of scorpion stings to cause PRES, emphasizing the importance of early recognition and intervention. Further research is required to know the underlying mechanisms and improve management strategies.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100216"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143918291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-23DOI: 10.1016/j.hmedic.2025.100219
Wajiha Arshad , Alifa Sabir , Sahab Ahmad , Muhammad Azam , Abdur Rehman , Arham Ihtesham , Shahzaib Maqbool , Saba Shafiq
{"title":"Surgical retrieval of fractured guidewire during percutaneous coronary intervention: A case report","authors":"Wajiha Arshad , Alifa Sabir , Sahab Ahmad , Muhammad Azam , Abdur Rehman , Arham Ihtesham , Shahzaib Maqbool , Saba Shafiq","doi":"10.1016/j.hmedic.2025.100219","DOIUrl":"10.1016/j.hmedic.2025.100219","url":null,"abstract":"<div><div>Percutaneous coronary intervention (PCI) is a common treatment for coronary artery disease, but rare complications, such as guidewire fracture, can occur. This report describes a 63-year-old Southeast Asian male with inferior wall myocardial infarction (IWMI) who underwent primary PCI at a secondary care center. While revascularizing the right coronary artery (RCA), the guidewire fractured during left circumflex artery (LCX) stenting. Transferred to a tertiary unit in an unstable condition, redo-angiography revealed the fractured guidewire lodged in the distal left main stem (LMS). After unsuccessful percutaneous retrieval attempts, the patient underwent coronary artery bypass grafting (CABG). The guidewire was successfully retrieved from the LMS and aorta. Although rare, guidewire fractures during PCI can cause severe complications like vessel perforation, thrombus, and embolization. Early detection and management, including surgical intervention when required, are vital to prevent life-threatening outcomes.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100219"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143870436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-23DOI: 10.1016/j.hmedic.2025.100214
Luis E. Martínez-Bravo , Diego A. Hidalgo-Díaz , Ricardo Téllez-Marroquín
{"title":"Unmasking tuberculosis - Immune reconstitution inflammatory syndrome manifested as meningitis","authors":"Luis E. Martínez-Bravo , Diego A. Hidalgo-Díaz , Ricardo Téllez-Marroquín","doi":"10.1016/j.hmedic.2025.100214","DOIUrl":"10.1016/j.hmedic.2025.100214","url":null,"abstract":"<div><div>Unmasking tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) is an inflammatory reaction to HIV infection that is developed after antiretroviral therapy is initiated and a tuberculosis diagnosis is made within three months. We described a young male living with HIV who developed unmasking TB-IRIS, which manifested as tuberculous meningitis. Steroids and antitubercular treatment were initiated with a good clinical response, but the patient later developed acute respiratory distress syndrome. In the context of unmasking TB-IRIS, both entities are unusually concurrent. This case illustrates a rare but fatal complication that could develop in individuals living with HIV following antiretroviral and antitubercular treatment.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100214"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143870243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combination of airway pressure release ventilation and furosemide-induced metabolic alkalosis in a pediatric patient with severe acute respiratory distress syndrome: A case report","authors":"Norihiko Tsuboi, Kaoru Tsuboi, Eisaku Nashiki, Shotaro Matsumoto, Satoshi Nakagawa","doi":"10.1016/j.hmedic.2025.100217","DOIUrl":"10.1016/j.hmedic.2025.100217","url":null,"abstract":"<div><div>Lung protective strategy is widely accepted in ventilator management for acute respiratory distress syndrome (ARDS). In addition to ventilator-induced lung injury, care must be taken to prevent patient self-inflicted lung injury while preserving the patient’s spontaneous breathing. We propose a new concept that furosemide-induced metabolic alkalosis may play a pulmonary protective role in ventilator management for ARDS. We present a pediatric patient with severe ARDS who was successfully treated with a combination of airway pressure release ventilation (APRV) and furosemide administration. The patient’s spontaneous breathing effort was reduced during APRV due to metabolic alkalosis and PaCO<sub>2</sub> remained over 60 mmHg while pH was maintained around 7.4.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100217"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143870242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rare case of female fragile X syndrome with uncommon association of hyperglycemia and diabetic ketoacidosis managed conservatively in a low resource setting – A case report","authors":"Md. Deluwar Hussen , Zareen Tabassum , Zahin Shahriar , Rukiya Nurjahan , Afefa khanam Mohona , Fareha Rezwana","doi":"10.1016/j.hmedic.2025.100210","DOIUrl":"10.1016/j.hmedic.2025.100210","url":null,"abstract":"<div><h3>Introduction</h3><div>Fragile X Syndrome (FXS) is the second most dominant cause of lifelong learning disability and the most common inherited cause of autism. While FXS is explicitly diagnosed in males, females show mild features thus early diagnosis is complicated in areas with no access to genetic testing and molecular diagnosis. Here, we report a case of FXS in a female patient with a rare manifestation of DKA.</div></div><div><h3>Case presentation</h3><div>This case was a 16-year-old female admitted with unconsciousness and hyperglycemia diagnosed with DKA. Additional physical examination showed signs typical for FXS such as long face, narrow brow, large ears, and connective tissue dysfunction in the form of flat foot and joint hypermobility. Due to limited resources molecular testing was not done, but clinical index of suspicion for FXS was high given the family history and physical examination.</div></div><div><h3>Discussion</h3><div>This case portrays the key signs and symptoms in diagnosing FXS in females as most of these signs are likely to be mild. This form of presentation with DKA is not usual in patients diagnosed with FXS and should serve as a reminder that there may be rare association. The absence of genetic testing in low income areas exacerbates the problem of diagnosis.</div></div><div><h3>Conclusion</h3><div>This case demonstrates that, despite the absence of genetic confirmation, symptoms of this condition can be identified in a patient early enough, and the results can be improved. Family history and the physical examination should be emphasized in these situations.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100210"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-21DOI: 10.1016/j.hmedic.2025.100208
Kartavya Kumar Verma, Nighat Hussain
{"title":"A challenging case of acute lymphoblastic leukemia with bone marrow necrosis","authors":"Kartavya Kumar Verma, Nighat Hussain","doi":"10.1016/j.hmedic.2025.100208","DOIUrl":"10.1016/j.hmedic.2025.100208","url":null,"abstract":"<div><h3>Background</h3><div>Acute lymphoblastic leukemia (ALL) is the most prevalent hematological malignancy in children. The use of corticosteroids without an accurate diagnosis can result in serious complications. In this discussion, we highlight a case of undiagnosed ALL in which corticosteroid treatment created diagnostic dilemmas and led to delays in diagnosis. Additionally, we examine the value of special stains, immunohistochemistry, and comprehensive diagnostic approaches in managing this intricate case.</div></div><div><h3>Case report</h3><div>An 18-year-old male arrived at our facility exhibiting severe cachexia. He had previously sought treatment for fever, malnutrition, and headaches. Bone marrow and peripheral blood examinations displayed significant cytopenia across all lineages with marrow necrosis. Upon reviewing his medical history, we discovered that he had been treated with corticosteroids, which suppressed all blood lineages and hindered the ability to diagnose ALL. The patient was diagnosed with ALL based on the results of the peripheral blood smear analysis and flow cytometry performed seven days after the bone marrow examination.</div></div><div><h3>Conclusion</h3><div>This case indicates that even a few doses of corticosteroids can modify the presentation of undiagnosed ALL, making diagnosis challenging due to the bone marrow's response to anti-inflammatory medications. Therefore, a comprehensive workup is crucial before initiating any treatment, including corticosteroids, as they can disrupt the precise haematological diagnostic parameters necessary for identifying conditions like leukemia.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100208"},"PeriodicalIF":0.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-20DOI: 10.1016/j.hmedic.2025.100207
Chloe Lahoud , Toni Habib , Michel Al Achkar , Tyler Grantham , Nissar Ahmed
{"title":"A rare case of massive colonic distention secondary to undiagnosed colon adenocarcinoma","authors":"Chloe Lahoud , Toni Habib , Michel Al Achkar , Tyler Grantham , Nissar Ahmed","doi":"10.1016/j.hmedic.2025.100207","DOIUrl":"10.1016/j.hmedic.2025.100207","url":null,"abstract":"<div><h3>Introduction</h3><div>Colonic distention is a critical condition arising from various abdominal pathologies. It necessitates both timely diagnosis and intervention to prevent severe complications such as ischemia or perforation.</div></div><div><h3>Case</h3><div>We present the case of a 69-year-old male with an 8-month history of progressive abdominal distention, minimal bowel movements, occasional vomiting, and significant weight loss. Imaging revealed high-grade colonic dilatation with a severe diffuse stool burden. Consequently, a self-expandable metallic stent (SEMS) was placed successfully, relieving the obstruction and serving as a bridge to elective surgical management.</div></div><div><h3>Conclusion</h3><div>This case highlights the subtle and insidious progression of symptoms in some patients with malignant colonic obstruction, sometimes leading to a delayed presentation and diagnosis. It emphasizes the role of SEMS as an effective, minimally invasive intervention as a bridge for definitive surgical management. Early recognition and intervention in cases of progressive colonic distention are critical to optimizing patient outcomes.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100207"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ReportsPub Date : 2025-04-18DOI: 10.1016/j.hmedic.2025.100206
Valentina Picariello , Andrea Sibilio , Francesca Brandini , Sara Puglisi , Debora Anconelli , Sofia Nosseir , Luca Saragoni , Dolores Santini
{"title":"Metaplastic breast cancer with heterologous mesenchymal differentiation (osseous and chondroid): A case report and review of the literature","authors":"Valentina Picariello , Andrea Sibilio , Francesca Brandini , Sara Puglisi , Debora Anconelli , Sofia Nosseir , Luca Saragoni , Dolores Santini","doi":"10.1016/j.hmedic.2025.100206","DOIUrl":"10.1016/j.hmedic.2025.100206","url":null,"abstract":"<div><div>This report describes a rare case of metaplastic breast carcinoma (MpBC) with heterologous mesenchymal differentiation (osseous and chondroid) in a 72-year-old woman. The patient presented with a lump in the right breast which initially posed diagnostic difficulties due to its unusual radiological features. Imaging studies, including mammography, ultrasound, and MRI, revealed a tumor with mesenchymal differentiation, which was confirmed by ultrasound-guided core-needle biopsy. We discuss the clinical course, the typical resistance to chemotherapy seen in MpBC, and the surgical treatment undertaken, comparing these findings with data from the current literature. This case highlights the need for a comprehensive multimodal evaluation for an accurate diagnosis of MpBC.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"12 ","pages":"Article 100206"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interconnected pathophysiology: Psoriatic lesions bridging the skin and oral mucosa in an elderly patient","authors":"Akanksha Singh , Rika Singh , Praveen Kumar Rathore , Pushpendra Singh","doi":"10.1016/j.hmedic.2025.100196","DOIUrl":"10.1016/j.hmedic.2025.100196","url":null,"abstract":"<div><h3>Objectives</h3><div>Psoriasis is a chronic inflammatory skin condition that can present in various forms, including oral lesions, which are less frequently reported. This case highlights the challenges posed by the absence of histopathological confirmation through biopsy in diagnosing oral psoriasis, relying instead on clinical correlation and exclusion of other conditions.</div></div><div><h3>Methods</h3><div>We present a case of a 61-year-old male patient with a long-standing history of skin psoriasis who developed significant oral lesions. A clinical diagnosis of oral psoriasis was made based on the clinical features, exclusion of other conditions, and the patient's history, despite the lack of an oral biopsy.</div></div><div><h3>Results</h3><div>After 3 months of treatment with topical corticosteroids and systemic methotrexate, the patient showed significant improvement, with reduced oral lesions and substantial clearance of skin plaques.</div></div><div><h3>Conclusion</h3><div>This case underscores the interconnected nature of skin and oral psoriasis, emphasizing the need for histopathological confirmation in ambiguous cases. However, clinical correlation can be an effective diagnostic approach when histopathology is unavailable. A multidisciplinary approach is essential for managing such complex cases.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"11 ","pages":"Article 100196"},"PeriodicalIF":0.0,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}