Neurosarcoidosis masquerading as cerebral metastasis lesion: Case report

Abstract

Sarcoidosis is a chronic multisystemic granulomatous disease that is still of an unknown etiology. Neurosarcoidosis refers to the manifestations of sarcoidosis affecting central or peripheral nervous system. Due to its multiorgan tropism, sarcoidosis can mimic a metastatic disease. We report a case of a patient who was initially suspected of having a cerebral metastatic lesion. Subsequent investigations suggested an association with multiple lung lesions, but no primary cancer was identified. Histopathological examination of a biopsied lung nodule revealed noncaseating granulomas, establishing an unexpected diagnosis of sarcoidosis. Following this diagnosis, steroid treatment was initiated, resulting in a favorable response.