Medical Reports最新文献

Confronting a colossal challenge: A case report and literature review on the diagnosis and management of a 40 cm, 3.3 kg phyllodes tumor 面对巨大的挑战：40 cm， 3.3 kg叶状肿瘤的诊断和治疗的病例报告和文献综述

Medical Reports Pub Date : 2025-07-09 DOI: 10.1016/j.hmedic.2025.100311

Ahmad Jradi , Mohamad Al Qassab , Sereina Ghattas , Nadim Chaarani , Philippe Attieh , Karam Karam , Walid Salamoun

{"title":"Confronting a colossal challenge: A case report and literature review on the diagnosis and management of a 40 cm, 3.3 kg phyllodes tumor","authors":"Ahmad Jradi , Mohamad Al Qassab , Sereina Ghattas , Nadim Chaarani , Philippe Attieh , Karam Karam , Walid Salamoun","doi":"10.1016/j.hmedic.2025.100311","DOIUrl":"10.1016/j.hmedic.2025.100311","url":null,"abstract":"<div><div>With a peak incidence in women of 45–49 years old, phyllodes tumors (PT) are uncommon fibroepithelial neoplasms that make up less than 1 % of all breast tumors. Based on histological features, these tumors are categorized into benign, borderline, and malignant subtypes, with the malignant subtype having the worst prognosis and highest chance of recurrence. Diagnosing PT remains challenging due to its similarities with fibroadenomas (FA), necessitating the use of core needle biopsy for accurate differentiation. Our 59-year-old female patient described in this report had a borderline PTs that had grown to a remarkable 40 × 35 × 10 cm size and was causing serious clinical issues, such as skin ulceration. Following a modified mastectomy, an intermediate-grade PT with negative surgical margins was verified by histological examination. Since the tumor was within 1 mm from the posterior margin, adjuvant radiation therapy was recommended. A comprehensive review of the literature was performed to explore the diagnostic challenges, imaging modalities, histopathological features, and treatment approaches for PT, including surgical resection, the role of radiation therapy, and the limited efficacy of chemotherapy. To guarantee the best possible results for patients with PTs, this case emphasizes the need of early detection and the necessity for precise surgical intervention.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100311"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144597141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A polypoid mucosa-associated lymphoid tissue lymphoma causing gastric outlet obstruction: A case report and literature review 息肉样黏膜相关淋巴组织淋巴瘤引起胃出口梗阻1例报告并文献复习

Medical Reports Pub Date : 2025-07-09 DOI: 10.1016/j.hmedic.2025.100313

Chakib Khoury , Rebal Nahas , Karam Karam , Emanuel-Youssef Dib , Elias Fiani

引用次数: 0

Spontaneous passage of a retained endoscopic capsule prior to scheduled surgery in a Crohn’s disease patient: A case report 克罗恩病患者预定手术前保留内窥镜胶囊的自然通过：一例报告

Medical Reports Pub Date : 2025-07-08 DOI: 10.1016/j.hmedic.2025.100312

Salma Barakat , Sarah Ahmed , Ahmed Rafei , Rawan A. Bedab , Abdelmounem E. Abdo

{"title":"Spontaneous passage of a retained endoscopic capsule prior to scheduled surgery in a Crohn’s disease patient: A case report","authors":"Salma Barakat , Sarah Ahmed , Ahmed Rafei , Rawan A. Bedab , Abdelmounem E. Abdo","doi":"10.1016/j.hmedic.2025.100312","DOIUrl":"10.1016/j.hmedic.2025.100312","url":null,"abstract":"<div><h3>Background</h3><div>Video capsule endoscopy (VCE) is a noninvasive tool used to evaluate small bowel diseases, including Crohn’s disease, suspected small bowel bleeding, malabsorption, and chronic diarrhea. A known complication is capsule retention (CR), particularly in patients with established Crohn’s disease and undetected strictures. While CR often requires endoscopic or surgical removal, spontaneous passage has been reported following medical therapy.</div></div><div><h3>Case summary</h3><div>We present the first documented case in Sudan of a 28-year-old male with Crohn’s disease who experienced capsule retention, followed by spontaneous passage. The patient had a 7-year history of chronic diarrhea, weight loss, and post-defecation abdominal pain. Initial imaging and endoscopy were inconclusive. A small bowel follow-through confirmed luminal patency, and VCE was performed, revealing classic Crohn’s features and suggesting a terminal ileal stricture. Two weeks later, X-ray showed the capsule retained in the right colon, and surgery was planned. However, a follow-up radiograph before surgery confirmed spontaneous passage, likely aided by corticosteroid and mesalamine therapy.</div></div><div><h3>Conclusion</h3><div>This case underscores the importance of evaluating for strictures before VCE in Crohn’s patients. Conservative treatment may promote capsule passage in selected cases, avoiding invasive intervention. Use of patency capsules and cross-sectional imaging is recommended to minimize retention risk.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100312"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144614274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurosarcoidosis masquerading as cerebral metastasis lesion: Case report 以脑转移灶为伪装的神经结节病1例

Medical Reports Pub Date : 2025-07-07 DOI: 10.1016/j.hmedic.2025.100310

O. Lahjouji , I. Chaouche , H. Ouazzani , A. Akammar , N. El Bouardi , M. Haloua , M.Y. Alaoui Lamrani , M. Boubbou , M. Maâroufi , B. Alami

引用次数: 0

Spinal epidural abscess in infants: Case report and review of the literature 婴儿脊髓硬膜外脓肿：病例报告及文献复习

Medical Reports Pub Date : 2025-07-05 DOI: 10.1016/j.hmedic.2025.100303

Tomas Leng , Ayesha Ali

{"title":"Spinal epidural abscess in infants: Case report and review of the literature","authors":"Tomas Leng , Ayesha Ali","doi":"10.1016/j.hmedic.2025.100303","DOIUrl":"10.1016/j.hmedic.2025.100303","url":null,"abstract":"<div><div>Spinal epidural abscess (SEA) is an uncommon but serious condition in children, where timely diagnosis is essential to avoid permanent neurological complications. Diagnosing SEA in pediatric patients, particularly in infants, is challenging due to nonspecific symptoms such as fever and pain, which are often difficult to interpret and can lead to delayed or missed diagnoses. This report details the case of a 10-month-old otherwise healthy infant with an extensive SEA, where fluorine-18 fluorodeoxyglucose PET/CT (F-FDG PET CT) was effectively used to confirm the diagnosis. Additionally, we conducted a comprehensive literature review from January 2000 to October 2024 to explore clinical presentations and imaging considerations unique to infants with SEA. Of the 124 cases reviewed, 13 met our inclusion criteria. The most common symptoms were fever and irritability, followed by motor deficits. The primary pathogen was MSSA, affecting the cervical spine in most cases, and the majority of infants received antibiotics, with most undergoing neurosurgical intervention, and no deaths were reported in the cohort. This case, along with the review, underscores the importance of early recognition and advanced imaging approaches in enhancing diagnostic accuracy and improving outcomes for pediatric SEA. F-FDG PET CT can be diagnostically useful in certain infant cases of occult bacteremia where no obvious infection source is identified.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100303"},"PeriodicalIF":0.0,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144571194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pericardial decompression syndrome after small-volume pericardiocentesis: A case report when even less is too much 小容积心包穿刺后心包减压综合征1例

Medical Reports Pub Date : 2025-07-05 DOI: 10.1016/j.hmedic.2025.100309

Ahmed Basuoni , Marwa Ahmed , Karim Abdel Hakim , Sulaiman Al Maqbali , Waleed DawElbeit

{"title":"Pericardial decompression syndrome after small-volume pericardiocentesis: A case report when even less is too much","authors":"Ahmed Basuoni , Marwa Ahmed , Karim Abdel Hakim , Sulaiman Al Maqbali , Waleed DawElbeit","doi":"10.1016/j.hmedic.2025.100309","DOIUrl":"10.1016/j.hmedic.2025.100309","url":null,"abstract":"<div><h3>Background</h3><div>Pericardial decompression syndrome (PDS) is a rare but potentially life-threatening complication following pericardial drainage, typically associated with large-volume effusion removal of more than 1 L within 1 h.</div></div><div><h3>Case summary</h3><div>We report the case of a 62-year-old man with metastatic thymic carcinoma and severe mitral regurgitation who developed acute pulmonary edema and transient left ventricular dysfunction following pericardiocentesis. Despite draining only 600 mL of pericardial fluid, the patient developed respiratory failure, pulmonary edema and required mechanical ventilation. Echocardiography revealed a drop in ejection fraction and elevated filling pressures. Prompt recognition and supportive management, including diuresis and intensive care monitoring, led to full recovery of cardiac function within days.</div></div><div><h3>Conclusion</h3><div>This case highlights that PDS may develop even after small-volume pericardial drainage in patients with compromised cardiac reserve. Proposed mechanisms include preload-afterload mismatch, myocardial stunning, and adrenergic withdrawal. Awareness, early diagnosis, and careful pericardial fluid removal are key to preventing and managing PDS even in draining small amount especially with underlying structural heart disease or baseline reduced left ventricular function.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100309"},"PeriodicalIF":0.0,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144571192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intestinal spirochetosis 肠道螺旋体病

Medical Reports Pub Date : 2025-07-05 DOI: 10.1016/j.hmedic.2025.100308

Bipneet Singh , Jack Visser , Sakshi Bai , Jahnavi Ethakota , Palak Grover , Gurleen Kaur , Syed-Mohammed Jafri

{"title":"Intestinal spirochetosis","authors":"Bipneet Singh , Jack Visser , Sakshi Bai , Jahnavi Ethakota , Palak Grover , Gurleen Kaur , Syed-Mohammed Jafri","doi":"10.1016/j.hmedic.2025.100308","DOIUrl":"10.1016/j.hmedic.2025.100308","url":null,"abstract":"<div><div>Intestinal spirochetosis involves the colonization of the colonic epithelium by Brachyspira. Patients may be asymptomatic or present with diarrhea, abdominal pain, and bloating. It generally affects immunocompromised individuals. Diagnosis requires colonoscopy with biopsies and specific staining, often missed due to its rarity. Treatment typically involves metronidazole, with macrolides as alternatives, but relapse can occur, necessitating better follow-up and documentation. We present four cases that highlight diverse presentations and responses to treatment. A 36-year-old male with multiple sclerosis (MS) and psoriasis, who experienced symptom resolution with metronidazole; a 23-year-old male with abdominal pain and diarrhea, who improved with clarithromycin; an 86-year-old diabetic with chronic diarrhea who responded to metronidazole but experienced a relapse; and a 54-year-old male with HIV-AIDS, who was treated for concurrent H. pylori with no recurrence. Diagnostic challenges arise due to symptom variability and slow growth on culture. Treatment with metronidazole is effective but prone to relapse, possibly due to spirochete translocation within colonic crypts. More research is needed to establish clear diagnostic markers, understand epidemiological patterns, and develop effective long-term treatments.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100308"},"PeriodicalIF":0.0,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144597142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ewing sarcoma of maxilla masquerading as odontogenic lesion; And role of NKX2.2 for confirmatory diagnosis: A rare case report 假造牙源性病变的上颌骨尤文氏肉瘤NKX2.2在确诊中的作用：罕见病例报告

Medical Reports Pub Date : 2025-07-05 DOI: 10.1016/j.hmedic.2025.100306

Nikita Kashyap , Debarati Ray , Divya Nadiminti , S. Aravindan , Jay Gopal Ray

引用次数: 0

Disseminated intravascular coagulation: An unexpected signpost to ulcerative colitis: A case report 弥散性血管内凝血：溃疡性结肠炎的意外提示：1例报告

Medical Reports Pub Date : 2025-07-04 DOI: 10.1016/j.hmedic.2025.100304

Toni Habib , Chloe Lahoud , Zaid Khamis , Muhammad Abdullah , Hadi Itani , Hassan Al Moussawi

引用次数: 0

Progressive neck deformation after intramedular cervical tumor removal by laminoplasty approach 椎板成形术切除颈髓内肿瘤后进行性颈部变形

Medical Reports Pub Date : 2025-07-03 DOI: 10.1016/j.hmedic.2025.100305

Dmytro Ishchenko

{"title":"Progressive neck deformation after intramedular cervical tumor removal by laminoplasty approach","authors":"Dmytro Ishchenko","doi":"10.1016/j.hmedic.2025.100305","DOIUrl":"10.1016/j.hmedic.2025.100305","url":null,"abstract":"<div><div>Posterior approaches are usually used for the removal of tumors localized in the spinal canal, employing laminectomy techniques with the possibility of subsequent laminoplasty. However, even when bone defects are replaced with autografts, studies have shown a high likelihood of postoperative deformities, particularly in cases involving multisegment laminoplasty and radiotherapy. This risk increases with multisegmented laminoplasty and subsequent radiotherapy exposure. This study presents a clinical case of treating a patient with an intramedullary tumor from C2-Th1 after surgery using the laminoplasty technique, followed by adjuvant radiotherapy. After treatment, the patient developed pathological kyphosis of the cervical spine, with a Cobb angle of 82°. A comprehensive treatment approach was employed, which included fixation and traction in a HALO-vest apparatus, followed by anterior corporodesis and posterior occipitospinal fusion to achieve satisfactory correction and prevent further deformities and secondary spinal cord injuries. Deformities are a common complication of laminoplasty without additional stabilization. The contributing factors include the use of multilevel approaches, adjuvant radiotherapy, and pre-existing segmental instability. Careful planning is required to prevent pathological kyphosis and secondary spinal cord injury. This planning should consider the volume of bone defects, fixation techniques, subsequent treatment, initial range of motion, and type of primary physiological curvature.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"13 ","pages":"Article 100305"},"PeriodicalIF":0.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0