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Creatine Kinase (CK) elevation: An unusual presentation of celiac disease
Medical Reports Pub Date : 2025-02-01 DOI: 10.1016/j.hmedic.2024.100151
Jasmin Martin , Reshma Patel , Narayanan Venkatasubramani
{"title":"Creatine Kinase (CK) elevation: An unusual presentation of celiac disease","authors":"Jasmin Martin ,&nbsp;Reshma Patel ,&nbsp;Narayanan Venkatasubramani","doi":"10.1016/j.hmedic.2024.100151","DOIUrl":"10.1016/j.hmedic.2024.100151","url":null,"abstract":"<div><div>Celiac disease (CD) is an autoimmune disorder triggered by ingestion of gluten-containing products. Elevated Creatine Kinase (CK) etiologies include rhabdomyolysis, myocardial infarction or inflammatory myopathies. Very few reports of the association between CD and myopathies. Herein, we reported a 15-year-old with myalgia and weight loss, elevated CK, diagnosed with CD.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100151"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveiling rifampicin-resistant tuberculosis: A rare presentation as breast abscess in a 48-year-old patient-A case report
Medical Reports Pub Date : 2025-02-01 DOI: 10.1016/j.hmedic.2025.100161
Sandip B. Patil , Drishti L. Dulani , Valay N. Ashara , M. Ramya , Anil A. Pardeshi
{"title":"Unveiling rifampicin-resistant tuberculosis: A rare presentation as breast abscess in a 48-year-old patient-A case report","authors":"Sandip B. Patil ,&nbsp;Drishti L. Dulani ,&nbsp;Valay N. Ashara ,&nbsp;M. Ramya ,&nbsp;Anil A. Pardeshi","doi":"10.1016/j.hmedic.2025.100161","DOIUrl":"10.1016/j.hmedic.2025.100161","url":null,"abstract":"<div><div><em>Tuberculous mastitis</em> (TM) is a rare manifestation of tuberculosis (TB) that presents challenges in diagnosis and management. We present a case of a 48-year-old female enrolled in the endTB-Q trial who developed rifampicin-resistant TM, masquerading as a breast abscess. Despite a history of drug-sensitive TB and adherence to the antitubercular drug regimen, the patient later developed a breast lump during the trial. Imaging revealed an ill-defined lesion in the right breast, which was later confirmed as tuberculosis through molecular testing. Rifampicin resistance was detected, requiring a tailored treatment approach. The patient responded well to antitubercular therapy and lumpectomy. This highlights the importance of vigilance in diagnosing extrapulmonary TB manifestations, particularly in high TB burden settings. This case underscores the need for multidisciplinary management strategy for atypical presentations of TB.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100161"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An occult primary sclerosing cholangitis unmasked by cholangiography: A case report
Medical Reports Pub Date : 2025-02-01 DOI: 10.1016/j.hmedic.2025.100168
Karam Karam , Johny Salem , Sarah Jalloul , Lynn Daoud , Pierre Hani
{"title":"An occult primary sclerosing cholangitis unmasked by cholangiography: A case report","authors":"Karam Karam ,&nbsp;Johny Salem ,&nbsp;Sarah Jalloul ,&nbsp;Lynn Daoud ,&nbsp;Pierre Hani","doi":"10.1016/j.hmedic.2025.100168","DOIUrl":"10.1016/j.hmedic.2025.100168","url":null,"abstract":"<div><div>Primary sclerosing cholangitis (PSC) is a chronic and cholestatic liver disease. Inflammation, fibrosis and destruction of intra and extra-hepatic ducts are the hallmarks of PSC. Another similar immune-mediated cholangiopathy is primary biliary cholangitis (PBC) in which only intrahepatic ducts are affected and approximately 90–95 % of patients are found to be positive for anti-mitochondrial antibody (AMA). We herein present a rare case of a 50-year-old female presenting with arthralgias who was found to have anti-mitochondrial antibody (AMA)-positive PSC; a marker usually found to be exclusive to PBC. This manuscript adds an interesting layer of complexity to the differential diagnosis whereby a diagnosis of PSC should not be excluded in the setting of a positive AMA.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100168"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug-induced liver injury and the urgent need for improved diagnostic test
Medical Reports Pub Date : 2025-02-01 DOI: 10.1016/j.hmedic.2025.100170
Yoshiyasu Takefuji
{"title":"Drug-induced liver injury and the urgent need for improved diagnostic test","authors":"Yoshiyasu Takefuji","doi":"10.1016/j.hmedic.2025.100170","DOIUrl":"10.1016/j.hmedic.2025.100170","url":null,"abstract":"<div><div>A review conducted by the National Library of Medicine has associated antibiotics, antidepressants, and other medications with liver damage. Researchers examined thousands of cases, investigating risk factors, diagnostic challenges, and the role of gut bacteria. They particularly focused on specific medications, including doxycycline and cyclophosphamide. There is an urgent need for the development of more accurate diagnostic tests for human Drug-Induced Liver Injury (DILI). The new findings underscore the necessity for improved diagnostic tools, such as biomarkers, to identify drug-induced liver injury effectively.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100170"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Primary neuro-endocrine carcinoma of the oral cavity – Report of a rare case” [Med. Rep. 9 (2025) 100140]
Medical Reports Pub Date : 2025-02-01 DOI: 10.1016/j.hmedic.2024.100150
Pyne Rudra , Sil Shiladitya , Ghosh Subhankar , Saha Nilanjana
{"title":"Corrigendum to “Primary neuro-endocrine carcinoma of the oral cavity – Report of a rare case” [Med. Rep. 9 (2025) 100140]","authors":"Pyne Rudra ,&nbsp;Sil Shiladitya ,&nbsp;Ghosh Subhankar ,&nbsp;Saha Nilanjana","doi":"10.1016/j.hmedic.2024.100150","DOIUrl":"10.1016/j.hmedic.2024.100150","url":null,"abstract":"","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100150"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Necrosis of the greater omentum: A rare complication after Hartmann's pouch reversal surgery
Medical Reports Pub Date : 2025-02-01 DOI: 10.1016/j.hmedic.2024.100149
Rashed W. Alweshah , Ibrahim Fathi , Mostafa M. Farag , Mohamed Yassin , Ayman Nabawi
{"title":"Necrosis of the greater omentum: A rare complication after Hartmann's pouch reversal surgery","authors":"Rashed W. Alweshah ,&nbsp;Ibrahim Fathi ,&nbsp;Mostafa M. Farag ,&nbsp;Mohamed Yassin ,&nbsp;Ayman Nabawi","doi":"10.1016/j.hmedic.2024.100149","DOIUrl":"10.1016/j.hmedic.2024.100149","url":null,"abstract":"<div><div>Omental infarction, a rare condition marked by disrupted blood flow to the omentum and subsequent tissue necrosis, is an unusual complication of colorectal surgery. Even more exceptional is its occurrence following Hartmann’s pouch reversal procedure. We present a case of a 32-year-old male patient who was operated on for perforated diverticulitis. An initial sigmoidectomy combined with the creation of a Hartmann's pouch and descending colostomy was performed. Two months later, a Hartmann's reversal procedure was conducted. Four days postoperatively, the patient developed a fever, leukocytosis (26.18 × 10 ³/µL), and foul wound discharge. Computed tomography (CT) revealed suspicion of greater omental necrosis and an omental abscess, which was confirmed during an emergency laparotomy and surgically treated. Postoperatively, the patient was managed with targeted antibiotics, and his recovery was uneventful, leading to discharge in good health. This case highlights the need to consider rare complications such as omental abscesses and necrosis following colorectal surgeries. We discuss the rarity of this complication, its pathophysiology, and review related literature to provide a comprehensive understanding of the condition.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100149"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful mаnаgement of а twisted ovаriаn dermoid cyst during the second trimester of pregnаncy: А cаse report
Medical Reports Pub Date : 2025-02-01 DOI: 10.1016/j.hmedic.2025.100158
Oussama lamzouri , Imane Benhamou , Lamyae Errami , Chatbi Zainab , Hafsa Taheri , Hanane Saadi , Ahmed Mimouni
{"title":"Successful mаnаgement of а twisted ovаriаn dermoid cyst during the second trimester of pregnаncy: А cаse report","authors":"Oussama lamzouri ,&nbsp;Imane Benhamou ,&nbsp;Lamyae Errami ,&nbsp;Chatbi Zainab ,&nbsp;Hafsa Taheri ,&nbsp;Hanane Saadi ,&nbsp;Ahmed Mimouni","doi":"10.1016/j.hmedic.2025.100158","DOIUrl":"10.1016/j.hmedic.2025.100158","url":null,"abstract":"<div><div>Ovаriаn torsion is а rаre but serious complicаtion during pregnаncy, pаrticulаrly when аssociаted with lаrge ovаriаn mаsses. This cаse report presents а 42-yeаr-old grаvidа 2 pаrа 1 womаn with а history of cesаreаn section, who presented to the emergency depаrtment аt 16 weeks of gestаtion with аcute аbdominаl pаin. Clinicаl exаminаtion reveаled а pаlpаble left-sided mаss, аnd ultrаsound confirmed аn 11 cm twisted ovаriаn dermoid cyst. Initiаlly, а lаpаroscopic аpproаch wаs аttempted, but due to the lаrge size of the mаss аnd the grаvid uterus, the procedure wаs converted to а lаpаrotomy. А cystectomy wаs successfully performed, preserving the ovаry, аnd histopаthologicаl exаminаtion confirmed а benign dermoid cyst. The pаtient hаd аn uneventful postoperаtive recovery аnd wаs mаnаged with tocolytics to prevent uterine contrаctions. Follow-up ultrаsound demonstrаted а heаlthy intrаuterine pregnаncy, аnd the pаtient continued to receive routine prenаtаl cаre without further complicаtions. This cаse highlights the importаnce of timely intervention in ovаriаn torsion during pregnаncy to prevent potentiаl complicаtions such аs ovаriаn necrosis аnd fetаl loss. Аlthough lаpаroscopy is the preferred surgicаl аpproаch in mаny cаses, this report illustrаtes thаt lаpаrotomy remаins а sаfe аnd effective option when аnаtomicаl constrаints аre present. Surgicаl decision-mаking must be individuаlized bаsed on the size of the mаss, gestаtionаl аge, аnd clinicаl presentаtion to ensure fаvorаble outcomes for both the mother аnd fetus. This cаse underscores the need for flexibility in surgicаl mаnаgement аnd close monitoring postoperаtively.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100158"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Caesarean section in a patient with Aortico pulmonary window: A peculiar case report
Medical Reports Pub Date : 2025-02-01 DOI: 10.1016/j.hmedic.2024.100142
Sandeep Kundra, Snimer K. Sidhu, Shaveta Kundra, Erajot K. Sandhu, Jaspal Kaur
{"title":"Successful Caesarean section in a patient with Aortico pulmonary window: A peculiar case report","authors":"Sandeep Kundra,&nbsp;Snimer K. Sidhu,&nbsp;Shaveta Kundra,&nbsp;Erajot K. Sandhu,&nbsp;Jaspal Kaur","doi":"10.1016/j.hmedic.2024.100142","DOIUrl":"10.1016/j.hmedic.2024.100142","url":null,"abstract":"<div><h3>Background</h3><div>Aortopulmonary window (APW), results from failure of septation of the aorticopulmonary trunk during the fifth to eight weeks of gestational age. Patients with APWs rarely survive beyond early life stages without surgical interventions. Herein, we report anesthetic management of a woman who survived this disorder into adulthood and presented in a pregnant state and was taken up for cesarean delivery.</div></div><div><h3>Case presentation</h3><div>A 29 year female presented with 39 weeks pregnancy. Examination revealed a systolic murmur and cardiomegaly. Echocardiography revealed APW with left to right shunt. An emergency cesarean section under General Anesthesia (GA) was performed due to commencement of labor pains without adequate cervix dilatation.</div></div><div><h3>Conclusion</h3><div>The anesthetic management of a patient with APW is challenging, however, the present case describes the use of general anesthesia with good maternal and neonatal outcomes.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100142"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Desmoplastic ameloblastoma: A multicentric study of 18 case series with literature review
Medical Reports Pub Date : 2025-02-01 DOI: 10.1016/j.hmedic.2024.100148
Madhusudan Astekar , Roopa Rao , Karpagaselvi Sanjai , Krishna Sireesha Sundaragiri , Gaurav Sapra , Shylaja Sanjeevareddygari , Srikant Natarajan , Sima P. Odedra
{"title":"Desmoplastic ameloblastoma: A multicentric study of 18 case series with literature review","authors":"Madhusudan Astekar ,&nbsp;Roopa Rao ,&nbsp;Karpagaselvi Sanjai ,&nbsp;Krishna Sireesha Sundaragiri ,&nbsp;Gaurav Sapra ,&nbsp;Shylaja Sanjeevareddygari ,&nbsp;Srikant Natarajan ,&nbsp;Sima P. Odedra","doi":"10.1016/j.hmedic.2024.100148","DOIUrl":"10.1016/j.hmedic.2024.100148","url":null,"abstract":"<div><div>Ameloblastoma is the second most common odontogenic tumour and the most common one to be reported histopathologically. The six histological variants of ameloblastoma are well established in the diagnosis of ameloblastoma, among which desmoplastic type still presents challenges to clinicians. In this multi-centric case series, we have complied with various clinical, radiological and histopathological parameters to better understand a unique variant from cases diagnosed between 1993 and 2023. The calculated mean age for desmoplastic ameloblastoma in the present case series was 55.5 years, with a higher female predilection and two-thirds of cases in the anterior mandible. Radiologically, Type I and II were the predominant presentation. Histopathologically, stromal hyalinization and osteoplasia were noted. The 61.1 % of cases were associated with another sub-type of ameloblastoma. The varied presentation has necessitated a rethink of using newer radiological techniques for early diagnosis, treatment planning and newly defined histopathological criteria for ‘Hybrid’ ameloblastoma.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100148"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disseminated coccidioidomycosis following travel to an endemic region and COVID-19 infection: Case report and case-based literature review
Medical Reports Pub Date : 2025-02-01 DOI: 10.1016/j.hmedic.2025.100164
Iqra Qazi, Nicole Hancock
{"title":"Disseminated coccidioidomycosis following travel to an endemic region and COVID-19 infection: Case report and case-based literature review","authors":"Iqra Qazi,&nbsp;Nicole Hancock","doi":"10.1016/j.hmedic.2025.100164","DOIUrl":"10.1016/j.hmedic.2025.100164","url":null,"abstract":"<div><div>Coccidioidomycosis, also known as valley fever, is a fungal infection caused by inhalation of soilborne spores. It primarily affects the respiratory system and presents with symptoms ranging from mild flu-like illness to severe pneumonia. Here we report a case of a 68-year-old male with fevers, worsening fatigue, and rash following a recent COVID-19 diagnosis. The patient had traveled to Florida, Arizona, Mexico, and Nevada within a month prior to symptom onset. Imaging revealed a lung nodule with associated mediastinal lymphadenopathy. Biopsy confirmed disseminated coccidioidomycosis. This case emphasizes the necessity of including coccidioidomycosis in the differential diagnosis for patients with respiratory symptoms and rashes, particularly those with recent travel to endemic regions. Heightened clinical awareness and prompt diagnostic evaluation are crucial for timely management.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100164"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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