Journal of Natural Pesticide Research最新文献

{"title":"Seasonal influence of shade on the disease incidence of Moniliophthora perniciosa in cocoa: Longitudinal study","authors":"Marco Vizuete-Montero ,&nbsp;Hilter Figueroa -Saavedra ,&nbsp;Rolando Torres-Castillo ,&nbsp;Maritza Chaglla-Cango","doi":"10.1016/j.napere.2025.100162","DOIUrl":"10.1016/j.napere.2025.100162","url":null,"abstract":"<div><div>Ecuador’s Amazon region is a global hotspot for fine-flavor cacao production, yet yields are frequently threatened by witches’ broom disease (<em>Moniliophthora perniciosa</em>) which can reduce harvests by more than 30 %. This longitudinal comparative study evaluates the seasonal influence of shade on the disease incidence of cocoa witches’ broom (<em>M. perniciosa</em>) in Ecuadorian Amazon region. Fifteen fine-flavor cacao farms were selected, distributed across the provinces of Sucumbíos and Orellana, establishing experimental plots with controlled shade management and control plots with traditional management. Over 60 months, shade variables were measured, and the incidence of the disease known as “witch’s broom” was assessed. Results indicate that experimental plots exhibited a higher percentage of shade (43.7 %) compared to control plots (35.33 %) during the summer. This increase in shade was correlated with greater disease incidence of <em>M. perniciosa</em>, evidenced by an increase in the number of terminal and floral broom formations. ARIMA models applied revealed that seasonal shade management significantly influences disease incidence, with projections showing stable temporal conditions in experimental plots compared to the seasonal variability in control plots. The research concludes that proper shade management can reduce the incidence of <em>M. perniciosa</em>, providing a more stable and predictable microclimate. These findings underscore the importance of integrating phytosanitary management strategies and sustainable agroforestry practices to mitigate the effects of climate change and improve the resilience of cacao production systems.</div></div>","PeriodicalId":100809,"journal":{"name":"Journal of Natural Pesticide Research","volume":"14 ","pages":"Article 100162"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145157520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artocarpus heterophyllus Lam. leaf extracts: Chemical insights and toxicity assessment against the lesser mealworm Alphitobius diaperinus Panzer (Coleoptera: Tenebrionidae)","authors":"Gabriel da Silva Coutinho ,&nbsp;Nataly Diniz de Lima Santos ,&nbsp;Juliana Vital de Mendonça ,&nbsp;Welton Aaron de Almeida ,&nbsp;Janaina Carla Barbosa Machado ,&nbsp;Júlio César Ribeiro de Oliveira Farias de Aguiar ,&nbsp;Daniela Maria do Amaral Ferraz Navarro ,&nbsp;Marcus Mello Rego de Amorim ,&nbsp;Jeine Emanuele Santos da Silva ,&nbsp;Magda Rhayanny Assunção Ferreira ,&nbsp;Luiz Alberto Lira Soares ,&nbsp;Patrícia Maria Guedes Paiva ,&nbsp;Thiago Henrique Napoleão ,&nbsp;Lucas Gabriel Pita dos Santos ,&nbsp;Emmanuel Viana Pontual","doi":"10.1016/j.napere.2025.100166","DOIUrl":"10.1016/j.napere.2025.100166","url":null,"abstract":"<div><div><em>Alphitobius diaperinus</em>, a pervasive pest in poultry facilities and stored products, poses significant challenges due to its role as a mechanical carrier of pathogens and its resilience to conventional insecticides. In search of eco-friendly alternatives, this study investigated the chemical composition and insecticidal potential of saline (SE) and methanolic (ME) extracts from <em>Artocarpus heterophyllus</em> leaves. Chromatographic analyses (TLC and HPLC-DAD) revealed the presence of cinnamic acid derivatives and flavonoids in both extracts, while terpenes and steroids were detected exclusively in ME. Gas chromatography–mass spectrometry revealed the presence of eleven volatile compounds in each extract, with sesquiterpenes such as β-caryophyllene, α-humulene, and caryophyllene oxide dominating the ME profile, whereas SE predominantly contained long-chain alkanes. Bioassays against <em>A. diaperinus</em> adults showed that ME significantly reduced survival rates (LC₅₀ = 36.99 ± 1.57 mg/mL), while SE was ineffective at comparable concentrations. The insecticidal activity of ME may be linked to the presence of sesquiterpenes, steroids, and flavonoids. These findings position the methanolic extract of <em>Ar. heterophyllus</em> as a promising candidate for the development of plant-based insecticides, potentially contributing to more sustainable and targeted pest control strategies in poultry farming.</div></div>","PeriodicalId":100809,"journal":{"name":"Journal of Natural Pesticide Research","volume":"14 ","pages":"Article 100166"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of insecticidal efficacy of aromatic plant leaf oil extracts on the adults of Sitophilus oryzae Linnaeus 1763 (Coleoptera: Curculionidae) and Tribolium castaneum Herbst 1797 (Coleoptera: Tenebrionidae)","authors":"Subramanian Arivoli ,&nbsp;Samuel Tennyson","doi":"10.1016/j.napere.2025.100171","DOIUrl":"10.1016/j.napere.2025.100171","url":null,"abstract":"<div><div>Post-harvest infestation of cereals and pulses by insect pests causes serious qualitative and quantitative losses to stored grains. Indiscriminate use of chemical insecticides have led to negative effects on the environment, pest resistance and resurgence, insecticide resistance, emergence of genetically resistant insect strains, chemical residues in food products and human health effects. Plant oils extracted from aromatic plants exhibit a wide range of insecticidal properties and are regarded as safe substitutes for traditional synthetic insecticides against stored grain insect pests. Hence, the objective of this study was to investigate the potential of oils extracted from aromatic plant leaves against two of the most pervasive and damaging insect pests of stored products worldwide, viz., <em>Sitophilus oryzae</em> and <em>Tribolium castaneum</em>. The aromatic plant leaf oil extracts were analyzed for its phytochemical compounds via GC-MS and tested for its toxicity on the adults of <em>S</em>. <em>oryzae</em> and <em>T</em>. <em>castaneum</em> at dosages of 0.62, 1.25, 2.50, 5.00, and 10.00 µL/L by Petri dish filter paper disc bioassay method. Adult mortality was calculated 24, 48 and 72 h after exposure. <em>Azadirachta indica</em>, <em>Chrysopogon zizaniodes</em>, <em>Citrus sinensis</em> and <em>Mentha piperita</em> achieved 100.0 % adult mortality in <em>S</em>. <em>oryzae</em> at 10.00 µL/L after 72 h of exposure, and their respective LD₅₀ values were 1.02, 1.16, 1.38 and 1.50 µL/L. <em>A</em>. <em>indica</em> and <em>Cymbopogon nardus</em> caused a maximum of 96.6 % and 95.8 % adult mortality in <em>T</em>. <em>castaneum</em>, respectively at 10.00 µL/L after 72 h of exposure, and their respective LD₅₀ values were 1.49 and 1.90 µL/L. <em>A</em>. <em>indica</em>, <em>C</em>. <em>nardus</em>, <em>M</em>. <em>piperita</em> and <em>M</em>. <em>fragrans</em> showed pronounced adult mortality and their toxicity factor ranged from 1.00 to 1.58 against both <em>S</em>. <em>oryzae</em> and <em>T</em>. <em>castaneum</em> after 72 h. The major phytocompounds present in the aromatic plant leaf oil extracts belonged to the class of terpenoids and terpenes. The present study highlighted the significance and scope of aromatic plant leaf oil extracts for the management of <em>S</em>. <em>oryzae</em> and <em>T</em>. <em>castaneum</em> in integrated pest management.</div></div>","PeriodicalId":100809,"journal":{"name":"Journal of Natural Pesticide Research","volume":"14 ","pages":"Article 100171"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145473489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential of bionematicides in suppressing Pratylenchus zeae and changing the bacterial community in the rhizosphere of sugarcane (Saccharum officinarum)","authors":"Mayanna Karlla Lima Costa ,&nbsp;Janderson Moura da Silva ,&nbsp;Sandra Mara Barbosa Rocha ,&nbsp;Romário Martins Costa ,&nbsp;Francisco de Alcântara Neto ,&nbsp;Heriksen Higashi Puerari ,&nbsp;Aurenivia Bonifácio ,&nbsp;Vania Maria Maciel Melo ,&nbsp;Arthur Prudencio de Araujo Pereira ,&nbsp;Ademir Sérgio Ferreira Araujo","doi":"10.1016/j.napere.2025.100156","DOIUrl":"10.1016/j.napere.2025.100156","url":null,"abstract":"<div><div>Sugarcane (<em>Saccharum officinarum L.</em>) is a major global crop for ethanol production and plays a critical role in meeting global bioenergy needs. However, its growth is threatened by nematode parasites, including <em>Pratylenchus zeae</em>, which disrupts root function and reduces productivity. While traditional chemical control presents several issues, the use of bionematicides in biological control is an eco-friendly alternative to managing nematode populations while preserving the microbiome of the rhizosphere. Here, we tested five bionematicides containing microorganisms: i) MicrosAtivos™ (<em>Bacillus subtilis)</em>, ii) Nemacontrol™ (<em>Bacillus amyloliquefaciens),</em> iii) Biotrinsic™ (<em>Pseudomonas oryzihabitans</em>), iv) Quartzo™ (<em>Bacillus subtilis</em> + <em>Bacillus licheniformis</em>), v) Profix™ (<em>Purpureocillium lilacinum</em> + <em>Bacillus subtilis</em> + <em>Bacillus licheniformis</em>) to suppress <em>P. zeae</em> in sugarcane roots and soil. Biotrinsic™ (<em>P. oryzihabitans)</em> demonstrated the highest efficiency, reducing <em>P. zeae</em> populations by approximately 64 % in the soil and 81 % in the roots. Similarly, Nemacontrol™ (<em>B. amyloliquefaciens</em>) achieved reductions of 63 % in the soil and 72 % in the roots. In contrast, Quartzo™ (<em>B. subtilis</em> + <em>B. licheniformis</em>) exhibited the lowest efficiency, with reductions of 47 % in the soil and 30 % in the roots. While suppressing <em>P. zeae</em>, these treatments induced only minor changes in the structure of native bacterial communities in the rhizosphere. These results highlight the effectiveness of specific bionematicides, particularly <em>P. oryzihabitans</em> and <em>B. amyloliquefaciens</em>, in suppressing <em>P. zeae</em> while preserving the native rhizosphere microbiome, showing the potential of these biological tools for nematode management in sugarcane cultivation.</div></div>","PeriodicalId":100809,"journal":{"name":"Journal of Natural Pesticide Research","volume":"14 ","pages":"Article 100156"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Paederia foetida L. volatile oil as a green insecticide against groundnut seed beetles (Caryedon serratus)","authors":"Lalit Chowdhury ,&nbsp;Sarada Prasad Mohapatra ,&nbsp;Manoja Das","doi":"10.1016/j.napere.2025.100149","DOIUrl":"10.1016/j.napere.2025.100149","url":null,"abstract":"<div><div>The groundnut bruchid, <em>Caryedon serratus</em> is a significant pest of stored groundnut (<em>Arachis hypogaea</em> L., family: Fabaceae, order: Fabales) grains. The pest negatively impacts peanut quality and market acceptance as they internally consume seeds. A study was carried out in the laboratory to determine whether the volatile oil found in the aerial portions of <em>Paederia foetida</em> L. is effective in controlling the groundnut pest <em>Caryedon serratus</em>. The morphological characters, molecular taxonomy, and systematic position of the plant were identified. The volatile oils present in the plant parts were extracted using Clevenger's apparatus and tested as a natural biopesticide against <em>C. serratus</em>. The active phytocompounds found in <em>P. foetida</em> volatile oil were identified by gas chromatography and mass spectrometry (GCMS). Two concentrations of the volatile oil, such as 50 % and 100 %, were applied for 96 h to different stages of <em>C. serratus</em> in the laboratory condition. Both concentrations significantly reduced the mortality rate of <em>C. serratus</em> eggs and adults. The maximum percentages of reduced hatching of eggs and death of larvae of the insects were 95.6 ± 0.07 % and 92.0 ± 0.10 %, respectively. The application of volatile oil resulted in an imbalance in the sex ratio of the insect, and the value was 0.30. The percentage of adult mortality of <em>C. serratus</em> was 91.0 ± 0.02 % after 4 days of the volatile oil treatment. Further, the oil also affected the fecundity of females developed from <em>C. serratus</em> eggs as well as the various developmental phases of insects. The investigation concludes that outcomes are limited to laboratory conditions only, and an extensive field validation is required before recommending large-scale application.</div></div>","PeriodicalId":100809,"journal":{"name":"Journal of Natural Pesticide Research","volume":"14 ","pages":"Article 100149"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144831386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential of moroccan entomopathogenic nematodes in controlling polyphagous fruit flies, Drosophila melanogaster (Meigen, 1830) and D. simulans (Sturtevant, 1919), under variable abiotic conditions in strawberry agroecosystems","authors":"Najwa Seddiqi Kallali ,&nbsp;Nabila El Alami ,&nbsp;Salah-Eddine Laasli ,&nbsp;Samake Broulaye ,&nbsp;Youssef Benseddik ,&nbsp;Khalid Khfif ,&nbsp;Abdelmalek Boutaleb-Joutei ,&nbsp;Abderrahman Ouijja ,&nbsp;Fouad Mokrini ,&nbsp;Rachid Lahlali","doi":"10.1016/j.napere.2025.100153","DOIUrl":"10.1016/j.napere.2025.100153","url":null,"abstract":"<div><div><em>Drosophila</em> species, specifically <em>Drosophila melanogaster</em> (Meigen, 1830) and <em>Drosophila simulans</em> (Sturtevant<em>,</em> 1919), are one of the most economically damaging pests in red berry production systems, particularly strawberry crops. Insect pests have traditionally been controlled through the application of chemical insecticides, which can severely damage the environment and pose serious risks to human health. An environmentally friendly alternative for controlling and managing pests is biological control using entomopathogenic nematodes (EPNs) as a possible biological control agent. This study evaluated the virulence of four indigenous Moroccan EPN strains, <em>Steinernema feltiae</em> (SF-MOR9, SF-MOR10) and <em>Heterorhabditis bacteriophora</em> (HB-MOR1, HB-MOR2) under controlled laboratory and greenhouse conditions against third instar larvae of <em>D. melanogaster</em> and <em>D. simulans</em>. Bioassays examined the effects of abiotic factors: two temperatures (25 °C and 28 °C), three photoperiods (light, obscurity, and 12:12 h L/O), three doses of EPNs (25, 50, 100 IJs cm^-²), and two substrate sources (soil and fruit). Nematode efficacy varied significantly with temperature, photoperiod, species, and dose. <em>H. bacteriophora</em> strains, particularly HB-MOR2, achieved consistent mortality rates exceeding 97 % under optimal conditions. These findings highlight the potential of indigenous Moroccan EPNs, especially <em>H. bacteriophora,</em> as sustainable biological control agents for integrated pest management (IPM) of <em>Drosophila</em> species in strawberry agroecosystems</div></div>","PeriodicalId":100809,"journal":{"name":"Journal of Natural Pesticide Research","volume":"14 ","pages":"Article 100153"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145019236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Side-effects of Beauvericin Nano-Chitosan formulation on some economic and physiological characteristics of Bombyx mori L","authors":"Leila Yousefi-Lardeh ,&nbsp;Arash Zibaee ,&nbsp;Farjad Rafeie ,&nbsp;Ramin Abdoli","doi":"10.1016/j.napere.2025.100168","DOIUrl":"10.1016/j.napere.2025.100168","url":null,"abstract":"<div><div>Beauvericin is a cyclic hexadepsipeptide mycotoxin produced mainly by <em>Beauveria bassiana</em> and <em>Fusarium</em> spp. This mycotoxin has insecticidal, antimicrobial, antiviral, and cytotoxic properties hence it may be potentially used as a pesticide and medicine in some specific areas. Following our previous study on production a chitosan-based nano-formulation of beauvericin to control mulberry snout moth, the current study was designed to determine whether the nano-formulation may affect physiological mechanisms and economic characteristics of <em>Bombyx mori</em> L. Results showed the statistical decrease of nutritional indices except for approximate digestibility. Statistical decrease was also recorded in the activity of digestive enzymes except for lipase and amino-peptidase that were in accordance of findings on the nutritional indices. In contrast, chitosan-based nano-formulation of beauvericin significantly induced the activity of antioxidant enzymes except for superoxide dismutase. The chitosan-based nano-formulation of beauvericin statistically decreased the weight of pupae and cocoon compared to control. Since we used LC₅₀ concentration of beauvericin in nano-formulation, it may be concluded that beauvericin had a severe effect on <em>B. mori</em> so there should be a reasonable period between spraying against <em>G. pyloalis</em> and utilization of leaves by <em>B. mori</em>.</div></div>","PeriodicalId":100809,"journal":{"name":"Journal of Natural Pesticide Research","volume":"14 ","pages":"Article 100168"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145332381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of femtosecond laser irradiation on survival and morphology of Tribolium castaneum","authors":"Heba Abdel-Tawab ,&nbsp;Shawky M. Aboelhadid ,&nbsp;Aya E. Mohamed ,&nbsp;Tarek Mohamed","doi":"10.1016/j.napere.2025.100172","DOIUrl":"10.1016/j.napere.2025.100172","url":null,"abstract":"<div><div>The use of chemical fumigants such as methyl bromide and phosphine to control red flour beetle has a negative impact on human health and environment. Moreover, effectiveness of these compounds has declined due to emergence of pesticides resistance. This emphasizes the need for safer and more sustainable alternatives. Physical control methods such as laser pulses represent powerful and environmentally safe option. Therefore, the present study investigated effectiveness of femtosecond laser light (FSL) on the survival of adult and larval stages of <em>Tribolium castaneum</em>. Femtosecond laser irradiation at 370 nm wavelength, 150 mW power, and 5 min exposure time induced 0 % survivability of adult and larval stages of <em>T. castaneum.</em> While, using femtosecond laser light at 400 nm wavelength under the same parameters resulted in complete inhibition of survivability in adults, and larval survival decreased to 33.33 %. Scanning electron microscopy (SEM) analysis of larvae revealed that 370 nm irradiation wavelength caused visible physical damage, including deformations in the dorsal cuticle, shrinkage of the abdominal surface and pygopods, loss of setae, and bulging. Similarly, the laser treatment of <em>T. castaneum</em> adults led to a reduction in elytra sensilla density and shrinkage of the ovipositor. In conclusion, femtosecond laser light showed pesticidal activity and induced physical damage against <em>T. castaneum</em>. Further studies are required to evaluate this effect under the field conditions.</div></div>","PeriodicalId":100809,"journal":{"name":"Journal of Natural Pesticide Research","volume":"14 ","pages":"Article 100172"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Artemisia essential oils as natural larvicides for Culex mosquito control","authors":"Abdellatif Alami ,&nbsp;Yassine Ez zoubi ,&nbsp;Mouhcine Fadil ,&nbsp;Fatima zahrae Radi ,&nbsp;Meriem El Hallabi ,&nbsp;Mohammed Ouali Alami ,&nbsp;Abdellah Farah","doi":"10.1016/j.napere.2025.100141","DOIUrl":"10.1016/j.napere.2025.100141","url":null,"abstract":"<div><div>Vector-borne diseases account for approximately 17 % of all infectious diseases, posing a significant threat to global health. Mosquitoes, among the most notorious vectors, transmit deadly pathogens such as West Nile virus, dengue, and malaria, contributing to over 700,000 deaths annually—disproportionately affecting vulnerable populations. The overuse of synthetic pesticides has led to environmental pollution and widespread pest resistance, necessitating the development of eco-friendly alternatives, including plant-derived essential oils (EOs). <em>Artemisia</em> species (Asteraceae family) produce diverse bioactive compounds, such as terpenoids and sesquiterpene lactones, which demonstrate potent larvicidal activity against mosquito vectors like <em>Culex pipiens</em>. This review explores the botanical characteristics, chemical composition, and bioactive properties of <em>Artemisia</em> species, focusing on their EOs as natural bioinsecticides. Special attention is given to the larvicidal efficacy of <em>Artemisia</em> EOs against <em>C. pipiens</em> and recent advancements in encapsulation techniques to enhance their longevity and effectiveness. Given the escalating challenges of insecticide resistance and mosquito-borne diseases, <em>Artemisia</em> EOs represent a sustainable and promising alternative for integrated vector control strategies.</div></div>","PeriodicalId":100809,"journal":{"name":"Journal of Natural Pesticide Research","volume":"13 ","pages":"Article 100141"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144563268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heraclenin, a bioactive furanocoumarin from fruits of Aegle marmelos induces potent insecticidal effects on Spodoptera frugiperda","authors":"Haripriya Shanmugam ,&nbsp;Ramkumar Haran ,&nbsp;Selva Rani Suppu Ramu ,&nbsp;Shanthi Mookiah ,&nbsp;Saranya Nallusamy","doi":"10.1016/j.napere.2025.100144","DOIUrl":"10.1016/j.napere.2025.100144","url":null,"abstract":"<div><div>The study evaluates the insecticidal efficacy of heraclenin, a natural compound purified from bael (<em>Aegle marmelos</em>) fruits, against <em>Spodoptera frugiperda</em> (fall armyworm), a major agricultural pest. Bioassay results demonstrated that heraclenin induces substantial larval mortality, achieving 86.66 % mortality at 1000 mg/L after 72 h of exposure. In addition, heraclenin exhibited a dose-dependent antifeedant effect, with a 93.69 % reduction in feeding activity observed at the highest concentration tested. Sub-lethal doses significantly inhibited larval growth, resulting in reduced weight gain and extended developmental periods, signifying its growth-regulatory potential. Molecular docking and dynamics simulations revealed stable binding interaction between heraclenin and the acetylcholinesterase enzyme of <em>S. frugiperda</em>, supporting its neurotoxic mode of action. Interestingly, <em>in silico</em> ADMET analysis indicated a favorable safety profile, suggesting minimal human toxicity risk. These findings provide strong evidence for developing heraclenin as a safe and environmentally sustainable biopesticide for effective crop protection, though further field evaluations are required.</div></div>","PeriodicalId":100809,"journal":{"name":"Journal of Natural Pesticide Research","volume":"13 ","pages":"Article 100144"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144614376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}