A pesticide powder prepared from four Chinese herbal medicine extracts as the active ingredient: Optimization of preparation process and quality examination

Zeyi Luo, Shengjun Ma, Yanyan Zhang, Hui Li, Yuting Yuan
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Abstract

To optimize the preparation process of a wettable powder using four traditional Chinese medicine extracts, namely Artemisia argyi Lévl. et Van., Sophora alopecuroides L., Hippophae rhamnoides L. and Juniperus sabina L., which are used as raw materials for the production of traditional Chinese medicine extract wettable powder, by adding suitable carriers and additives. Traditional Chinese medicine extract wettable powder was prepared by directly mixing the raw materials, carriers, and additives, followed by grinding and sieving. Types of carriers, dispersants, wetting agents, the ratio of dispersant to wetting agent, and the amount of additives were examined as factors in the optimization of the preparation process for the wettable powder using the orthogonal experimental design method, based on the single-factor experiment. When the carrier is bentonite, the dispersant is calcium lignosulfonate, the wetting agent is tide laundry detergent, the ratio of dispersant to wetting agent is 1: 9, the amount of additives added is 15 %, the comprehensive score of the prepared wettable powder is the highest, being up to 80.64 %, the quality inspection meets the general requirements. The optimized preparation process of the traditional Chinese medicine extract wettable powder is demonstrated to be feasible and provides a reference and technical support for further development and subsequent field trials of extract powders.
以四种中草药提取物为有效成分制备农药粉剂:工艺优化及质量检验
以艾叶四种中药提取物为原料,优选可湿性粉剂的制备工艺。等车。以苦参、沙棘、桧为原料,通过添加合适的载体和添加剂,制备中药提取液可湿性粉剂。采用原料、载体、助剂直接混合,粉碎、过筛的方法制备中药提取液可湿性粉剂。在单因素试验的基础上,采用正交试验设计方法,考察了载体类型、分散剂、润湿剂、分散剂与润湿剂的配比、添加剂的用量等因素对可湿性粉剂制备工艺的影响。当载体为膨润土,分散剂为木质素磺酸钙,润湿剂为潮汐洗衣粉,分散剂与润湿剂的比例为1:9,添加剂添加量为15 %时,制备的可湿性粉剂综合得分最高,可达80.64 %,质量检验符合一般要求。优选的中药提取液可湿性粉剂制备工艺是可行的,为提取液粉剂的进一步开发和后续的田间试验提供了参考和技术支持。
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