材料科学最新文献

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Green Carbon Dots/CaCO3/Abamectin Colloidal Pesticide Formulation for Safer and More Effective Pest Management
IF 17.1 1区 材料科学
ACS Nano Pub Date : 2024-12-21 DOI: 10.1021/acsnano.4c12707
Chuang Chen, Guopeng Teng, Weicheng Shen, Yijun Lu, Yuwei Jin, Xue Yuan, Kang Chen, Yue Yuan, Zhengyan Wu, Jia Zhang
{"title":"Green Carbon Dots/CaCO3/Abamectin Colloidal Pesticide Formulation for Safer and More Effective Pest Management","authors":"Chuang Chen, Guopeng Teng, Weicheng Shen, Yijun Lu, Yuwei Jin, Xue Yuan, Kang Chen, Yue Yuan, Zhengyan Wu, Jia Zhang","doi":"10.1021/acsnano.4c12707","DOIUrl":"https://doi.org/10.1021/acsnano.4c12707","url":null,"abstract":"An ideal green leaf-deposited pesticide formulation should offer advantages such as good water dispersibility, strong foliar affinity, sustained or controlled release of active ingredients, photostability and rain-fastness, minimal nontarget toxicity, use of nontoxic organic solvents, and degradable adjuvants. In line with this objective, we present green preparation of a colloidal pesticide formulation using optimized lysine-derived carbon dots (LysCDs)-modified CaCO<sub>3</sub> (LysCDs/CaCO<sub>3</sub>) particles as the carrier and abamectin (Abm) as the active ingredient. The loading capacity of abamectin in this colloidal pesticide (LysCDs/CaCO<sub>3</sub>/Abm) is 1.7 to 2.1 times higher than that of its counterpart (CaCO<sub>3</sub>/Abm) prepared without LysCDs, which is attributed to the increased specific surface area and pore volume of LysCDs/CaCO<sub>3</sub> particles. Due to the acid-induced degradation of CaCO<sub>3</sub>, the release of abamectin for LysCDs/CaCO<sub>3</sub>/Abm is accelerated under weakly acidic conditions, which is accompanied by the release of Ca<sup>2+</sup> ions and the fluorescence changes of LysCDs. The incorporation of LysCDs enhances the photostability and foliar adhesiveness of this colloidal pesticide, resulting in the highest degree of foliar retention when exposed to ultraviolet (UV) light or rainfall, compared to free-form abamectin and CaCO<sub>3</sub>/Abm. This results in the best performance of pest control on <i>Plutella xylostella</i> for LysCDs/CaCO<sub>3</sub>/Abm in both indoor and outdoor tests. Nontarget biocompatibility evaluations show that LysCDs/CaCO<sub>3</sub>/Abm exhibits lower acute toxicity to zebrafish and earthworms than free-form abamectin. In addition, this colloidal pesticide is favored by the minimal residue of the adjuvant material after abamectin release, which is converted into harmless Ca<sup>2+</sup> ions, CO<sub>2</sub>, and LysCDs. Therefore, this work designs a safer and more effective colloidal pesticide formulation to deliver abamectin with minimal adjuvant residue, realizing its trajectory as basically “circular and green”.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"18 797 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142867538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metal-organic framework derived carbon-based composites for high-performance microwave absorption
IF 23.2 2区 材料科学
Advanced Composites and Hybrid Materials Pub Date : 2024-12-21 DOI: 10.1007/s42114-024-01077-0
Shanshan Ran, Kai Sun, Minhui Zhao, Zhongyang Wang, Anoud Saud Alshammari, Mohamed H. Helal, Zeinhom M. El-Bahy, Yuan Yuan, Runhua Fan
{"title":"Metal-organic framework derived carbon-based composites for high-performance microwave absorption","authors":"Shanshan Ran,&nbsp;Kai Sun,&nbsp;Minhui Zhao,&nbsp;Zhongyang Wang,&nbsp;Anoud Saud Alshammari,&nbsp;Mohamed H. Helal,&nbsp;Zeinhom M. El-Bahy,&nbsp;Yuan Yuan,&nbsp;Runhua Fan","doi":"10.1007/s42114-024-01077-0","DOIUrl":"10.1007/s42114-024-01077-0","url":null,"abstract":"<div><p>There is an urgent need to develop high-performance absorbing materials to address the challenges of military stealth and daily electromagnetic pollution. Metal-organic frameworks (MOFs) are considered promising candidates due to their high porosity, large specific surface area, and tunable chemical structures. MOFs can be templates or precursors to transform into porous carbon, porous oxides, and metal-carbon composites at elevated temperatures. This paper reviews the synthesis strategies and recent advancements in MOF-derived carbon-based composites. The impact of various components and unique microstructures on these composites’ microwave absorption (MA) properties is analyzed. The discussion encompasses a range of composites, including porous carbon (PC) composites (such as metal/PC, metal oxide/PC, and metal/metal oxide/PC), as well as MOF derivatives combined with graphene, carbon nanotubes (CNTs), and carbon fibers (CFs). Additionally, the challenges and future directions regarding developing carbon-based microwave-absorbing materials (MAMs) derived from MOFs are discussed. This review aims to provide researchers with a comprehensive understanding of the design techniques pertinent to MOF-derived carbon-based composites in high-efficiency MAMs. </p></div>","PeriodicalId":7220,"journal":{"name":"Advanced Composites and Hybrid Materials","volume":"8 1","pages":""},"PeriodicalIF":23.2,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142859557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 4-year assessment of the qualitative characteristics of Slovenian barbecue lump charcoal and its compliance with the EN 1860-2 standard
IF 2.4 3区 农林科学
European Journal of Wood and Wood Products Pub Date : 2024-12-21 DOI: 10.1007/s00107-024-02164-1
Alessio Mencarelli, Darja Stare, Stefano Grigolato, Rosa Greco, Matevž Triplat
{"title":"A 4-year assessment of the qualitative characteristics of Slovenian barbecue lump charcoal and its compliance with the EN 1860-2 standard","authors":"Alessio Mencarelli,&nbsp;Darja Stare,&nbsp;Stefano Grigolato,&nbsp;Rosa Greco,&nbsp;Matevž Triplat","doi":"10.1007/s00107-024-02164-1","DOIUrl":"10.1007/s00107-024-02164-1","url":null,"abstract":"<div><p>The use of charcoal as a barbecue fuel is a widespread practice around the world. The quality of charcoal is essential to ensure the efficacy and safety of the grilling process. The European standards EN 1860-2:2023 establish the minimum quality requirements for barbecue charcoal for domestic and professional use. Given the significant variability in charcoal production techniques and raw materials, it is crucial to assess whether the commercial products available on the European market comply with standard regulatory requirements. This study evaluated the quality of barbecue charcoal available on the European market over four years: 2020, 2021, 2023, and 2024. A total of 42 charcoal bags were analyzed. Physical and chemical analyses were performed according to the referenced standards. The values obtained were compared with the limits required by the standards. The results revealed a high variability in the qualitative characteristics of charcoal among samples of different brands, both within the same year and in different years. Almost all of the samples analyzed (39) did not meet the standard limits. The most critical factors were low fixed carbon values and granulometry with high percentages of fine and coarse fractions. These findings suggest the need for improved regulations and stricter quality control to mitigate consumer risks.</p></div>","PeriodicalId":550,"journal":{"name":"European Journal of Wood and Wood Products","volume":"83 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142859739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing the Tribological Performance of MAO Coatings through Hydrostatic Extrusion of cp-Ti
IF 6.2 2区 材料科学
Journal of Alloys and Compounds Pub Date : 2024-12-21 DOI: 10.1016/j.jallcom.2024.178246
Ł. Maj, F. Muhaffel, A. Jarzębska, A. Trelka, K. Trembecka-Wójciga, J. Kawałko, M. Kulczyk, M. Bieda, H. Çimenoğlu
{"title":"Enhancing the Tribological Performance of MAO Coatings through Hydrostatic Extrusion of cp-Ti","authors":"Ł. Maj, F. Muhaffel, A. Jarzębska, A. Trelka, K. Trembecka-Wójciga, J. Kawałko, M. Kulczyk, M. Bieda, H. Çimenoğlu","doi":"10.1016/j.jallcom.2024.178246","DOIUrl":"https://doi.org/10.1016/j.jallcom.2024.178246","url":null,"abstract":"This study investigates the influence of plastic deformation of commercially pure titanium (cp-Ti) substrates on the tribological performance of micro-arc oxidation (MAO) coatings. Hydrostatic extrusion (HE) was employed to refine the microstructure of cp-Ti, producing ultrafine-grained (UFG) titanium, which was compared with coarse-grained (CG) cp-Ti. Both substrates were subjected to the MAO process, and the fabricated MAO coatings were analysed through X-ray diffraction (XRD), electron microscopy techniques (SEM and TEM), energy dispersive spectrometry, atomic force microscopy (AFM), and tribological testing (hardness, scratch and wear tests). The results show that HE-treated cp-Ti substrates promoted faster and thicker MAO coating formation, with superior adhesion and tribological properties compared to CG cp-Ti. The UFG substrate led to increased hardness and wear resistance, largely due to the higher density of grain boundaries and electrical resistance of the substrate, which accelerated oxide layer growth. It has been demonstrated that plastic deformation of the substrate via HE significantly enhances the performance of MAO coatings, providing improved surface protection for biomedical applications.","PeriodicalId":344,"journal":{"name":"Journal of Alloys and Compounds","volume":"31 1","pages":""},"PeriodicalIF":6.2,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142867159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of N substitution for Ni on the high-temperature oxidation resistance of GX40CrNiSi25-12 austenitic heat-resistant steel
IF 6.2 2区 材料科学
Journal of Alloys and Compounds Pub Date : 2024-12-21 DOI: 10.1016/j.jallcom.2024.178244
Qi Gao, Pengfei Xing, Guanyu Jiang, Mengwu Wu
{"title":"Effect of N substitution for Ni on the high-temperature oxidation resistance of GX40CrNiSi25-12 austenitic heat-resistant steel","authors":"Qi Gao, Pengfei Xing, Guanyu Jiang, Mengwu Wu","doi":"10.1016/j.jallcom.2024.178244","DOIUrl":"https://doi.org/10.1016/j.jallcom.2024.178244","url":null,"abstract":"In this paper, the effect of nitrogen (N) substitution for nickel (Ni) on the high-temperature oxidation resistance of austenitic heat-resistant steel was investigated based on GX40CrNiSi25-12 austenitic heat-resistant steel. The study also analyzed the differences in oxidation resistance among the test steels using oxidation thermodynamics and kinetics, as well as investigated how the morphology and structure of the oxide film impact high-temperature oxidation resistance. The results indicated that the introduction of the N element facilitated the formation of a protective oxide layer within the test steel, which impeded further reactions between the internal metal elements and external oxygen. The uniformly formed SiO<sub>2</sub> oxide layer significantly enhances the adhesion of the oxide film to the substrate, effectively preventing the shedding of oxides. Additionally, N promotes the development of chromium (Cr)-rich bands, which play a crucial role in inhibiting the growth of surface oxides and reducing the overall thickness of the oxide film. Moreover, the presence of N leads to improved densification of the surface oxide layer. This dense structure is instrumental in restricting ion diffusion, thereby decreasing the weight gain rate associated with high-temperature oxidation in the tested steel. Specifically, when the nitrogen content reached 0.32%, the oxidized weight gain and weight gain rate were reduced by 76.6% and 76.9%, respectively, compared to the steel without N addition. In conclusion, the substitution of nitrogen for nickel provides a highly effective means of enhancing the high-temperature oxidation resistance of austenitic heat-resistant steel. This research offers valuable insights for the future design of Ni-saving austenitic heat-resistant steel materials.","PeriodicalId":344,"journal":{"name":"Journal of Alloys and Compounds","volume":"5 1","pages":""},"PeriodicalIF":6.2,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142867161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and Characterization of Gold-Nanoparticle-Loaded Block Copolymer Vectors for Biomedical Applications: A Multivariate Analysis
IF 9.5 2区 材料科学
ACS Applied Materials & Interfaces Pub Date : 2024-12-21 DOI: 10.1021/acsami.4c16915
Talita de Francesco, Devon Richtsmeier, Seoyoon Lee, Magdalena Bazalova-Carter, Matthew G. Moffitt
{"title":"Synthesis and Characterization of Gold-Nanoparticle-Loaded Block Copolymer Vectors for Biomedical Applications: A Multivariate Analysis","authors":"Talita de Francesco, Devon Richtsmeier, Seoyoon Lee, Magdalena Bazalova-Carter, Matthew G. Moffitt","doi":"10.1021/acsami.4c16915","DOIUrl":"https://doi.org/10.1021/acsami.4c16915","url":null,"abstract":"Gold nanoparticles (GNPs) encapsulated in amphiphilic block copolymers are a promising system for numerous biomedical applications, although critical information on the effects of various preparation variables on the structure and properties of this unique type of nanomaterial is currently missing from the literature. In this research, we synthesized GNPs functionalized with thiol-terminated polycaprolactone (PCL-GNPs) before encapsulating them into poly(ε-caprolactone)-<i>b</i>-poly(ethylene glycol) (PCL-<i>b</i>-PEG) micellar nanoparticles via nanoprecipitation to yield GNP-loaded polymeric nanoparticles (GNP-PNPs). We explored the role of different manufacturing variables (water volume, PCL-<i>b</i>-PEG to PCL-GNP ratio, and PEG block length) on the sizes, morphologies, GNP occupancies, colloidal gold concentrations, and time stability of GNP-PNPs. Despite our motivation to increase colloidal gold concentrations for K-edge CT imaging applications, there was only moderate variation in the concentration of colloidal gold (<i>c</i><sub>Au</sub> = ∼100–150 μg/mL) over the range of investigated experimental variables; however, postformulation exposure to compressed air flow provided samples with increased gold concentrations and CT contrast above the visual threshold in imaging phantoms. The range of formulation variables also had only a weak effect on mean effective hydrodynamic diameters (<i>d</i><sub>h,eff</sub> = ∼150 nm). Statistical analysis of TEM images revealed that the mean number of GNPs within GNP-PNP vectors smaller than 50 nm, <i>Z</i><sub>ave,<i>d</i>&lt;50 nm</sub>, is generally higher for preparations involving PCL-<i>b</i>-PEG with the shorter of the two different PEG block lengths. Preparations with the shorter PEG block length copolymer were also found to produce GNP-PNP colloids with greater time stability in <i>d</i><sub>h,eff</sub> and <i>c</i><sub>Au</sub>. Consistent with our previous study using MB-MDA-231 cells, we found increased gold uptake in MCF-7 cells with increasing <i>Z</i><sub>ave,<i>d</i>&lt;50 nm</sub>. This study provides a roadmap for optimizing important figures of merit for existing biomedical applications, including CT imaging and radiotherapy sensitization, and for developing new diagnostic and therapeutic strategies using GNP-PNPs.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"13 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving nucleation of ALD films via the ion implantation pretreatment approach: Calculation and experiments
IF 6.7 2区 材料科学
Applied Surface Science Pub Date : 2024-12-21 DOI: 10.1016/j.apsusc.2024.162179
Dachen Deng, Xing Yan, Ling Tang, Yang Luo, Hua Li, Ye Xu, Liuhe Li, Mingyue Han
{"title":"Improving nucleation of ALD films via the ion implantation pretreatment approach: Calculation and experiments","authors":"Dachen Deng, Xing Yan, Ling Tang, Yang Luo, Hua Li, Ye Xu, Liuhe Li, Mingyue Han","doi":"10.1016/j.apsusc.2024.162179","DOIUrl":"https://doi.org/10.1016/j.apsusc.2024.162179","url":null,"abstract":"As a highly recommended approach, the atomic layer deposition (ALD) is widely applied to prepare the nanoscale thin films. To enable the development of ALD in high-quality films, overcoming the non-uniform film growth caused by heterogeneous distribution of reactive sites become vital and attractive nowadays. In this work, efforts for improving the nucleation of iridium (Ir) films on the rhenium (Re) substrates have been made using the pretreatment of plasma immersion ion implantation (PIII) combining with the magnetron sputtering. The related theories of this novel pretreatment method have been studied using the density functional theory (DFT) calculation. The ALD films prepared on the pretreated surfaces were characterized to investigate effects of pretreatment on the microstructure and elemental distribution for nucleation uniformity and film quality. Calculation and experimental results demonstrate that the ion implantation pretreatment on the Re substrate effectively modifies the surface microstructure, increases the density of active sites, and contributes to a well-modulated surface with enhanced homogeneity and affinity. The films deposited on the pretreated surface exhibit more uniform grain size, higher nucleation density, shorter grain spacing and thinner thickness. Our results may pave the way for the deposition of high-quality ALD films on low affinity surfaces.","PeriodicalId":247,"journal":{"name":"Applied Surface Science","volume":"53 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142867015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preparation of ultra-high dispersed monolayer of perfluoroepoxy-oligomer grafted graphene oxide and its application prospects in fluorinated functional materials
IF 6.7 2区 材料科学
Applied Surface Science Pub Date : 2024-12-21 DOI: 10.1016/j.apsusc.2024.162176
Yuan-Qi Wang, Bing-Yu Han, Jia-Xing Zhu, Jian-Gang Chen, Yingzhe Liu, Shukun Shen, Yinglei Wang, Zhao-Tie Liu, Zhong-Wen Liu, Jian Lu
{"title":"Preparation of ultra-high dispersed monolayer of perfluoroepoxy-oligomer grafted graphene oxide and its application prospects in fluorinated functional materials","authors":"Yuan-Qi Wang, Bing-Yu Han, Jia-Xing Zhu, Jian-Gang Chen, Yingzhe Liu, Shukun Shen, Yinglei Wang, Zhao-Tie Liu, Zhong-Wen Liu, Jian Lu","doi":"10.1016/j.apsusc.2024.162176","DOIUrl":"https://doi.org/10.1016/j.apsusc.2024.162176","url":null,"abstract":"An integrated strategy of ultrasound-enhanced graft/esterification of graphene oxide (GO) with hexafluoropropylene oxide oligomer ((HFPO)<sub>n</sub>-COX) (UEGGH) is successfully proposed/established to prepare the highly dispersed GO monolayer (F<sub>n</sub>GO-U). A series of F<sub>n</sub>GO-U is efficiently achieved in mild conditions with controllable structure via UEGGH, and characterized via FTIR, XPS, Raman, XRD, FETEM and AFM. By systematically experimental investigation and computational simulations, the key role of the fluorinated chains and ultrasound is discerned. It is proved that the ultrasound may synergistically enhance the intercalation, graft/esterification and exfoliation of GO with (HFPO)<sub>n</sub>-COX. Importantly, owing to the special repulsion among the grafted fluorinated chains and its effective inhibition to the spontaneous aggregation, F<sub>n</sub>GO-U exists most dominantly in monolayer, and can be excellently dispersed in solvents, liquid (fluorinated) oligomers and polymer solutions. Finally, F<sub>n</sub>GO-U is intentionally introduced/dispersed into PVDF-HFP and PFPE to evaluate/consolidate its superiority, and to develop its application in fluorinated functional materials. It was found that the mechanical properties and ionic conductivity of the prepared F<sub>n</sub>GO-U/PVDF-HFP composite membranes are approximately three times higher than those of PVDF-HFP membranes. Moreover, the wear volume of the prepared F<sub>n</sub>GO-U/PFPE composite lubricants is dramatically reduced to almost less than one fifth of magnitude compared to that of PFPE.","PeriodicalId":247,"journal":{"name":"Applied Surface Science","volume":"13 1","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142867020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced chemodynamic therapy for biofilm eradication: A self-supplied H2O2 nanoplatform with integrated photothermal property
IF 10.9 1区 材料科学
Journal of Materials Science & Technology Pub Date : 2024-12-21 DOI: 10.1016/j.jmst.2024.11.040
Dongxu Jia, Haixin Zhang, Wei Yang, Xinyan Zheng, Hu Xu, Yanxia Zhang, Qian Yu
{"title":"Enhanced chemodynamic therapy for biofilm eradication: A self-supplied H2O2 nanoplatform with integrated photothermal property","authors":"Dongxu Jia, Haixin Zhang, Wei Yang, Xinyan Zheng, Hu Xu, Yanxia Zhang, Qian Yu","doi":"10.1016/j.jmst.2024.11.040","DOIUrl":"https://doi.org/10.1016/j.jmst.2024.11.040","url":null,"abstract":"Bacterial biofilm infections, characterized by high mortality and challenging recovery, pose a significant global health risk. Developing innovative antibacterial materials and therapies, particularly those that mitigate resistance, is essential for effectively addressing biofilm-associated infections. Chemical dynamic therapy (CDT), which relies on hydroxyl radicals (·OH) generated from hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) to eliminate bacteria, has demonstrated potential in treating planktonic infections. However, traditional CDT is less effective against biofilm-related infections due to limited endogenous H<sub>2</sub>O<sub>2</sub> and the protective extracellular polymeric matrix within biofilms. In this study, a composite nanoplatform based on CuO<sub>2</sub> with self-supplying H<sub>2</sub>O<sub>2</sub> capabilities and Fe<sub>3</sub>O<sub>4</sub> with photothermal properties was designed to improve CDT efficacy for biofilm eradication. The Fe<sub>3</sub>O<sub>4</sub>/CuO<sub>2</sub> composite nanoparticles (FC NPs) were synthesized by incorporating CuO<sub>2</sub> into hollow mesoporous Fe<sub>3</sub>O<sub>4</sub> using an in-situ growth technique. Within the mildly acidic biofilm microenvironment, CuO<sub>2</sub> decomposes to release Cu<sup>2+</sup> and H<sub>2</sub>O<sub>2</sub>. The Cu<sup>2+</sup> subsequently catalyzes the Fenton-like conversion of the released H<sub>2</sub>O<sub>2</sub> into ·OH. Concurrently, near-infrared (NIR) irradiation of Fe<sub>3</sub>O<sub>4</sub> generates significant heat, boosting ·OH production and increasing bacterial membrane permeability, thereby enhancing bacterial vulnerability to ·OH. This nanoplatform demonstrated remarkable CDT efficacy, eradicating over 99.99% of methicillin-resistant <em>Staphylococcus aureus</em> (MRSA) and 99.97% of <em>Pseudomonas aeruginosa</em> biofilms within five minutes of NIR irradiation <em>in vitro</em>. Furthermore, <em>in vivo</em> experiments validated the nanoplatform's ability to eradicate biofilms and facilitate the healing of MRSA-infected wounds without adverse effects. This H<sub>2</sub>O<sub>2</sub> self-supplying and heat-enhancing approach presents a promising strategy to overcome the limitations of CDT in biofilm-related infection treatment.","PeriodicalId":16154,"journal":{"name":"Journal of Materials Science & Technology","volume":"76 1","pages":""},"PeriodicalIF":10.9,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142867155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements of thermoelectric nanomaterials in ROS-mediated broad-spectrum antibacterial therapies for wound healing
IF 10.9 1区 材料科学
Journal of Materials Science & Technology Pub Date : 2024-12-21 DOI: 10.1016/j.jmst.2024.11.039
Shiyu Jia, Cai Qi, Shengduo Xu, Lei Yang, Qiang Sun
{"title":"Advancements of thermoelectric nanomaterials in ROS-mediated broad-spectrum antibacterial therapies for wound healing","authors":"Shiyu Jia, Cai Qi, Shengduo Xu, Lei Yang, Qiang Sun","doi":"10.1016/j.jmst.2024.11.039","DOIUrl":"https://doi.org/10.1016/j.jmst.2024.11.039","url":null,"abstract":"Thermoelectric (TE) materials, with the ability to convert heat into electrical energy, can generate micro-electrical fields at electronic interfaces with biological systems, making them applicable in electric-catalyzing as nanozymes, and modulate the infected microenvironment of skin wounds. Thereby, by harnessing temperature differences <em>in vitro</em> or <em>in vivo</em>, TE nanomaterials can provide antimicrobial reactive oxygen species (ROS) by catalyzing redox reactions, thereby accelerating wound healing by suppressing infection. However, despite their promising potential, there is still a lack of comprehensive understanding of the antimicrobial mechanisms, biocompatibility, and practical applications of TE nanomaterials in wound healing, as this is a newly-emerged sub-area of energy-related biomedical applications. This review aims to address this gap by highlighting the emerging progress of TE materials in wound healing, clarifying their mechanism and advances, emphasizing their potential challenges for commercialization and clinical use, and proposing novel design strategies of TE nanomaterials for effective antibacterial performance.","PeriodicalId":16154,"journal":{"name":"Journal of Materials Science & Technology","volume":"83 1","pages":""},"PeriodicalIF":10.9,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142867156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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