Materials Letters最新文献

Integrating machine-learning and nanotechnology: imatinib-loaded nanomicelles for targeted therapy in MCF-7 breast cancer 整合机器学习和纳米技术：装载伊马替尼的纳米胶束用于MCF-7乳腺癌的靶向治疗

IF 2.7 4区材料科学

Materials Letters Pub Date : 2025-10-02 DOI: 10.1016/j.matlet.2025.139596

Abbas Rahdar , Sonia Fathi-karkan , Mohammad Javad Javid-Naderi , M. Ali Aboudzadeh

{"title":"Integrating machine-learning and nanotechnology: imatinib-loaded nanomicelles for targeted therapy in MCF-7 breast cancer","authors":"Abbas Rahdar , Sonia Fathi-karkan , Mohammad Javad Javid-Naderi , M. Ali Aboudzadeh","doi":"10.1016/j.matlet.2025.139596","DOIUrl":"10.1016/j.matlet.2025.139596","url":null,"abstract":"<div><div>Using machine-learning (ML) algorithms, we developed and characterized imatinib-loaded nanomicelles to enhance tumor-targeted delivery and reduce systemic toxicity. Nanomicelles were synthesized via an F127-mediated oil-in-water self-assembly process, achieving 65 % encapsulation efficiency and a uniform particle size of 257 nm. In-vitro studies showed pronounced pH-responsive release, with accelerated drug liberation at acidic pH (5.4) mimicking the tumor microenvironment and sustained release at physiological pH (7.4). To analyse release kinetics, we applied a supervised ML framework across eight regression algorithms. XGBoost delivered the best accuracy (R<sup>2</sup> = 0.998, MAE = 0.87) with strong cross-validation (CV, R<sup>2</sup> = 0.994). Modeling revealed 38–42 % faster release at pH 5.4, with time–pH interaction explaining 72 % of kinetic variability. These in-vitro results suggest that nanomicelles enable pH-triggered release and that ML can predict release kinetics, warranting further validation in biological systems.</div></div>","PeriodicalId":384,"journal":{"name":"Materials Letters","volume":"404 ","pages":"Article 139596"},"PeriodicalIF":2.7,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145227841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a continuous-flow microfluidic process for microsphere production 微球生产连续流微流控工艺的开发

IF 2.7 4区材料科学

Materials Letters Pub Date : 2025-10-02 DOI: 10.1016/j.matlet.2025.139599

Keerthi Renganathan , Ratnesh Jain , Darshan Chheda , Chandrakanth Gadipelly , Ganesh Gaikwad

引用次数: 0

Graphene-polymer composite for thin-film heating devices 石墨烯-聚合物复合薄膜加热装置

IF 2.7 4区材料科学

Materials Letters Pub Date : 2025-10-02 DOI: 10.1016/j.matlet.2025.139600

Artur Rimovich Yakhin , Azat Ravilevich Yusupov , Azat Faatovich Galiev , Anna Vladimirovna Mikhailova , Danfis Danisovich Karamov

引用次数: 0

Effect of sintering temperature on dielectric constant and electromagnetic shielding of La0.7Ca0.2Sr0.1CrO3 ceramics 烧结温度对La0.7Ca0.2Sr0.1CrO3陶瓷介电常数和电磁屏蔽的影响

IF 2.7 4区材料科学

Materials Letters Pub Date : 2025-09-30 DOI: 10.1016/j.matlet.2025.139595

Chenxu Li , Chuanbing Cheng , Yibo Li , Xuwei Bian , Chengshuai Gao , Xiaoran Zhang , Min Chen , Zhihao Wang , Yang Shen , Yao Liu

{"title":"Effect of sintering temperature on dielectric constant and electromagnetic shielding of La0.7Ca0.2Sr0.1CrO3 ceramics","authors":"Chenxu Li , Chuanbing Cheng , Yibo Li , Xuwei Bian , Chengshuai Gao , Xiaoran Zhang , Min Chen , Zhihao Wang , Yang Shen , Yao Liu","doi":"10.1016/j.matlet.2025.139595","DOIUrl":"10.1016/j.matlet.2025.139595","url":null,"abstract":"<div><div>In this paper, the negative permittivity of perovskite-type La<sub>0.7</sub>Ca<sub>0.2</sub>Sr<sub>0.1</sub>CrO<sub>3</sub> ceramics (LCSCOs) was reported for the first time. The effects of sintering temperature on their conductivity, permittivity, and electromagnetic shielding performance were explored. As the sintering temperature increased, the density of the LCSCOs increased. This enlarged the contact area between the grains and optimized the conductive pathways, consequently improving the electrical conductivity. Due to a certain number of free carriers in the LCSCOs, their collective oscillations resulted in negative permittivity. The elevated sintering temperature promoted the solid solubility of dopant atoms in ceramics, which ultimately resulted in an increase in the absolute values of negative permittivity. The Drude model could explain the negative permittivity. As the sintering temperature increased, the electromagnetic shielding performance of the ceramics improved due to the synergistic effect of increased density and conductivity.</div></div>","PeriodicalId":384,"journal":{"name":"Materials Letters","volume":"404 ","pages":"Article 139595"},"PeriodicalIF":2.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145227833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tribological performance of quenched diamond coatings on pure titanium under dry sliding conditions 干滑动条件下纯钛表面淬火金刚石涂层的摩擦学性能

IF 2.7 4区材料科学

Materials Letters Pub Date : 2025-09-30 DOI: 10.1016/j.matlet.2025.139592

Mahmoud Talaat Youssef , Mohamed Ragab Diab , Ahmed Hamed Oraby , Tomohiro Yoshida , Tsuyoshi Yoshitake , Abdelrahman Zkria Ahmed

引用次数: 0

Preparation and evaluation of a novel Schiff Base as a green corrosion inhibitor for mild steel in 1 M HCl 新型希夫碱绿色缓蚀剂在1 M盐酸中对低碳钢的制备及评价

IF 2.7 4区材料科学

Materials Letters Pub Date : 2025-09-30 DOI: 10.1016/j.matlet.2025.139585

Ruth Caroline Etroubeka, Hanlin Shao, Zhihao Chen, Wenzhong Yang

引用次数: 0

High-performance self-powered flexible photodetectors based on Sb₂Te₃/Te heterojunction nanostructures 基于Sb₂Te₃/Te异质结纳米结构的高性能自供电柔性光电探测器

IF 2.7 4区材料科学

Materials Letters Pub Date : 2025-09-30 DOI: 10.1016/j.matlet.2025.139593

Jiayin Wang , Kefei Cheng , Chuangjian Li , Fan Wang , Xianghan Ye , Kaijia Xu , Yinyin Qian

引用次数: 0

Design of a low-permittivity silicate garnet Ca3Ni2SiV2O12 with reduced sintering temperature 降低烧结温度的低介电常数硅酸盐石榴石Ca3Ni2SiV2O12的设计

IF 2.7 4区材料科学

Materials Letters Pub Date : 2025-09-30 DOI: 10.1016/j.matlet.2025.139594

Yang li, Xueling Hu, Yanjun Liu, Zejun Jiang

{"title":"Design of a low-permittivity silicate garnet Ca3Ni2SiV2O12 with reduced sintering temperature","authors":"Yang li, Xueling Hu, Yanjun Liu, Zejun Jiang","doi":"10.1016/j.matlet.2025.139594","DOIUrl":"10.1016/j.matlet.2025.139594","url":null,"abstract":"<div><div>A novel garnet composition, Ca<sub>3</sub>Ni<sub>2</sub>SiV<sub>2</sub>O<sub>12</sub>, was designed by incorporating both Si and V into the tetrahedral sites. The ceramics were synthesized via the conventional solid-state reaction method and sintered between 1080 and 1160 °C. X-ray diffraction and Rietveld refinement confirmed the formation of a pure cubic garnet phase (space group <em>Ia-3d</em>) across all temperatures. Microstructural analysis revealed that densification and grain growth improved with increasing sintering temperature. Optimal microwave dielectric properties were achieved at 1140 °C: a dielectric constant (<em>ε</em>ᵣ) of 8.2, a <em>Q</em> × <em>f</em> value of 21,960 GHz, and a temperature coefficient of resonant frequency (τ<sub><em>f</em></sub>) of approximately −45 ppm/°C. These results demonstrate that the strategic co-substitution of Si and V effectively lowers the sintering temperature while maintaining commendable dielectric performance, making Ca<sub>3</sub>Ni<sub>2</sub>SiV<sub>2</sub>O<sub>12</sub> a potential material for low-permittivity applications.</div></div>","PeriodicalId":384,"journal":{"name":"Materials Letters","volume":"404 ","pages":"Article 139594"},"PeriodicalIF":2.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145227827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tuning the magnetic ground state of CuCrO2 by Ge substitution 用Ge取代调整CuCrO2的磁性基态

IF 2.7 4区材料科学

Materials Letters Pub Date : 2025-09-29 DOI: 10.1016/j.matlet.2025.139574

Phantira Rattanathrum , Teerasak Kamwanna

{"title":"Tuning the magnetic ground state of CuCrO2 by Ge substitution","authors":"Phantira Rattanathrum , Teerasak Kamwanna","doi":"10.1016/j.matlet.2025.139574","DOIUrl":"10.1016/j.matlet.2025.139574","url":null,"abstract":"<div><div>Polycrystalline CuCr<sub>0.95</sub>Ge<sub>0.05</sub>O<sub>2</sub> was synthesized by a conventional solid-state reaction. X-ray diffraction confirmed the rhombohedral delafossite structure (R–3m). The refined lattice parameters are nearly identical to standard values, indicating Ge incorporation with minor distortion. Scanning electron microscopy (SEM) revealed hexagonal-like grains averaging of 3.6 ± 0.9 μm. Magnetic characterization showed weak ferromagnetism at low temperatures and paramagnetism at room temperature. Zero-field-cooled susceptibility identified a Curie temperature (<em>T</em><sub>C</sub>) of 139.3 ± 0.4 K, and Curie–Weiss fitting yielded a Curie constant (<em>C</em> = 1.425 ± 0.002), a Curie–Weiss temperature (Θ = −138.8 ± 0.4 K), and an effective magnetic moment (<em>μ</em><sub>eff</sub> = 3.37 μ<sub>B</sub>), consistent with the Cr<sup>3+</sup> sublattice. Additional field-dependent magnetization (<em>M</em>–<em>H</em>) loops near <em>T</em><sub>C</sub> revealed hysteresis in the 110–135 K range, with coercivity decreasing nearly linearly with temperature. Extrapolation yielded <em>T</em><sub>C</sub> = 139.8 ± 3.6 K, consistent with susceptibility results. These findings demonstrate that Ge substitution preserves the delafossite structure of CuCrO<sub>2</sub> while inducing weak ferromagnetic ordering, offering a route to tune the magnetic ground state.</div></div>","PeriodicalId":384,"journal":{"name":"Materials Letters","volume":"404 ","pages":"Article 139574"},"PeriodicalIF":2.7,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145227840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Robust filament formation via defect engineering in Mn: SrTiO3 for oxygen vacancy driven RRAM device 通过缺陷工程在Mn: SrTiO3中形成氧空位驱动RRAM器件的坚固灯丝

IF 2.7 4区材料科学

Materials Letters Pub Date : 2025-09-29 DOI: 10.1016/j.matlet.2025.139571

Durairaj Murugan , Gowtham Velpandi , Ranjith Ramadurai

引用次数: 0