Journal of Nanoparticle Research最新文献

Scaling nanopharmaceutical production for personalized medicine: challenges and strategies

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-04-10 DOI: 10.1007/s11051-025-06293-3

Carolina de Souza Cardoso Delfino, Michelle Colão de Paula Pereira, Marcella dos Santos Oliveira, Isabela de Carvalho Favareto, Viviane Silva Valladão, Milena de Oliveira Mota, Maria Victória Barros Costa, Ariane Jesus Sousa-Batista, Tiago Albertini Balbino

{"title":"Scaling nanopharmaceutical production for personalized medicine: challenges and strategies","authors":"Carolina de Souza Cardoso Delfino, Michelle Colão de Paula Pereira, Marcella dos Santos Oliveira, Isabela de Carvalho Favareto, Viviane Silva Valladão, Milena de Oliveira Mota, Maria Victória Barros Costa, Ariane Jesus Sousa-Batista, Tiago Albertini Balbino","doi":"10.1007/s11051-025-06293-3","DOIUrl":"10.1007/s11051-025-06293-3","url":null,"abstract":"<div><p>Nanomedicine has emerged as a transformative field, offering enhanced drug delivery systems with reduced toxicity through the use of nanopharmaceuticals. Scaling up the production of these systems is critical for the successful translation of personalized nanomedicine into clinical practice. This review addresses the challenges and strategies involved in large-scale manufacturing, focusing on key methodologies such as nanocrystallization, extrusion, supercritical fluid technology, and microfluidics. A detailed comparative analysis of these production methods reveals their scalability, cost implications, and impact on nanoparticle characteristics, such as size and reproducibility. Additionally, we examine the complex regulatory landscape, highlighting regional differences in approval requirements from agencies. These regulatory variations pose significant challenges for global manufacturers seeking to scale up production while maintaining compliance with diverse standards. The review also explores the critical role of good manufacturing practices (GMP) and quality-by-design approaches in ensuring batch-to-batch consistency, offering a roadmap for overcoming the technical and regulatory hurdles essential for advancing nanomedicine to widespread clinical applications. Therefore, by addressing these barriers, nanopharmaceuticals hold the potential to revolutionize personalized medicine with more effective, targeted therapies for complex diseases.</p></div>","PeriodicalId":653,"journal":{"name":"Journal of Nanoparticle Research","volume":"27 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143809109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanotechnology-assisted lung cancer diagnosis: biomarkers and imaging

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-04-10 DOI: 10.1007/s11051-025-06270-w

Sina Maskoukian, Ayda Moradi, Mahdi Shokri, Armina Shirangi, Tomasz Bączek, Navid Rabiee, Mohammad Reza Saeb, Mehdi Farokhi, Fatemeh Mottaghitalab

{"title":"Nanotechnology-assisted lung cancer diagnosis: biomarkers and imaging","authors":"Sina Maskoukian, Ayda Moradi, Mahdi Shokri, Armina Shirangi, Tomasz Bączek, Navid Rabiee, Mohammad Reza Saeb, Mehdi Farokhi, Fatemeh Mottaghitalab","doi":"10.1007/s11051-025-06270-w","DOIUrl":"10.1007/s11051-025-06270-w","url":null,"abstract":"<div><p>Lung cancer is one of the most deadly types of cancer, worldwide. It is essential to diagnose lung cancer in the early stage to accelerate the therapeutic process. The progress in nanotechnology-assisted therapies has revolutionized early diagnosis of lung cancer by developing non-invasive, selective, and highly sensitive nanostructures. Nanoparticles (NPs) have been widely used to improve the diagnosis and treatment of lung tumors due to their small size relative to human cells. The NPs can skip the barriers and target the proteins associated with tumor cells through either intracellular or extracellular action. Moreover, by using nanosensors, it is possible to detect specific biomarkers related to lung cancer in the early stages. This review is aimed at summarizing, classifying, and interpreting outcomes of reports on the application of NPs in detecting lung cancer. The survey revealed that NPs are used in three pathways to detect cancer, including detection of biomarkers, detection of cancer cells, and in vivo tumor imaging. Once the significance or limitation of each approach in the diagnosis of lung cancer is examined, their relative relevance is inferred.</p></div>","PeriodicalId":653,"journal":{"name":"Journal of Nanoparticle Research","volume":"27 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143809105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular dynamics simulation of nanoscale cutting mechanisms in single-crystal nickel-based superalloys with various crystal orientations

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-04-09 DOI: 10.1007/s11051-025-06304-3

Ping Zhang, Lingling Ning, Tengfei Zhang, Yan Yu

{"title":"Molecular dynamics simulation of nanoscale cutting mechanisms in single-crystal nickel-based superalloys with various crystal orientations","authors":"Ping Zhang, Lingling Ning, Tengfei Zhang, Yan Yu","doi":"10.1007/s11051-025-06304-3","DOIUrl":"10.1007/s11051-025-06304-3","url":null,"abstract":"<div><p>This study employs molecular dynamics simulations to investigate the nanoscale cutting behavior and dislocation evolution of single-crystal nickel-based superalloys under various crystallographic orientations and cutting conditions. The analysis focuses on shear strain, stress distribution, atomic structure transformation, and dislocation dynamics throughout the cutting process. The key results reveal distinct orientation-dependent behaviors. Under a 30° rotation about the X-axis (X30), increasing the cutting depth leads to a reduction in localized shear strain, while stress distribution exhibits pronounced regional patterns and the emergence of periodic twin boundaries. In the case of a 45° rotation (X45), the shear strain concentration reaches its peak, accompanied by depth- and orientation-dependent transformations of twin boundaries. For the 90° rotation (X90), cutting depth exerts a significant influence on both stress and shear strain distributions. Structurally, the X30 orientation is characterized by twin boundaries containing amorphous atoms. At X45, hexagonal close-packed (HCP) atomic layers initially form, with their extent varying according to the cutting depth. In the X90 configuration, both amorphous and body-centered cubic (BCC) atomic structures are markedly increased at a depth of 20 Å. Dislocation analysis further reveals orientation-specific trends. The X30 case features various non-standard dislocations whose densities change with cutting length. At X90, distinct dislocation types such as 1/2 < 110 > and 1/6 < 112 > emerge at specific depths, while other dislocation densities remain relatively low.</p></div>","PeriodicalId":653,"journal":{"name":"Journal of Nanoparticle Research","volume":"27 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnetic Ru catalyst in Heck, Suzuki, and Sonagashira C–C coupling reactions

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-04-08 DOI: 10.1007/s11051-025-06296-0

Hadieh Rahbar Kafshboran, Soheila Ghasemi

{"title":"Magnetic Ru catalyst in Heck, Suzuki, and Sonagashira C–C coupling reactions","authors":"Hadieh Rahbar Kafshboran, Soheila Ghasemi","doi":"10.1007/s11051-025-06296-0","DOIUrl":"10.1007/s11051-025-06296-0","url":null,"abstract":"<div><p>A thermo-responsive ruthenium catalyst was developed by grafting poly (<i>N</i>-isopropyl acrylamide) on silica-modified iron oxide nanoparticle core–shell (Fe<sub>3</sub>O<sub>4</sub>@Si) through free-radical polymerization process. The amino-functionalized support was obtained by exposing it to ethylenediamine. Further, the as-prepared compound was treated with ethylenediaminetetraacetic acid (EDTA), followed by embellishment with Ru NPs to form a well-organized heterogeneous catalytic structure (Fe<sub>3</sub>O<sub>4</sub>@Si-modified PNIPAAm-Ru). This unique system exhibits several remarkable features, including a broad distribution of catalytic sites, exceptional thermal stability, and the utilization of environmentally friendly solvents. Additionally, it offers significant features like easy separation and recyclability of the catalyst waste. Various characterization methods proved catalyst structure properly. The catalyst demonstrated a remarkable role in the carbon–carbon cross-coupling transformations of Sonogashira-Hagihara, Suzuki–Miyaura, and Mizoroki–Heck using different aryl halides under TBAB, copper, and amine-free conditions. One key advantage of this catalytic system is its ability to be reused for a minimum of 8 repetitions without any considerable decline in activity, structural changes, or leaching.</p></div>","PeriodicalId":653,"journal":{"name":"Journal of Nanoparticle Research","volume":"27 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green synthesized nano starch: preparation and emerging avenues in food industry 绿色合成纳米淀粉：制备方法和食品工业的新途径

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-04-07 DOI: 10.1007/s11051-025-06285-3

Valiathan Sreejit, Radhakrishnan Preetha, S Asmath Mubeena, Suresh Dhananjay

{"title":"Green synthesized nano starch: preparation and emerging avenues in food industry","authors":"Valiathan Sreejit, Radhakrishnan Preetha, S Asmath Mubeena, Suresh Dhananjay","doi":"10.1007/s11051-025-06285-3","DOIUrl":"10.1007/s11051-025-06285-3","url":null,"abstract":"<div><p>Green synthesis techniques have recently achieved significant attention due to their eco-friendliness and feasibility. The research on the production of nanoparticles from starch is gaining momentum since starch is non-toxic, renewable, and affordable. Reviews on the green synthesis of nano starch and its applications within the food industry are notably rare. This review illuminates the green synthesis of nano starch, highlighting its significant role in the food industry as a reinforcement agent for food packaging, a rheological modifier, an emulsion stabilizer, a nano-delivery system for food and nutraceutical bioactive constituents, a fat replacer, an antimicrobial stabilizer, and prebiotics. Green techniques for nano starch synthesis, such as enzyme hydrolysis, electrospinning, electrospraying, nanoprecipitation, self-assembly, cold plasma treatment, ball milling, ultrasonication, and high-pressure homogenization, have been delineated in this review. Nano starch, which is made using environmentally friendly methods, has special qualities like being biodegradable, biocompatible and having better barrier properties. These make it a great choice for use in the food industry. The health and safety aspects of administering green synthesized nano starch have been discussed. This review offers an overview of the green synthesis of nano starch and its utilization in the food industry that paves the way to the sustainable development of food industries.</p></div>","PeriodicalId":653,"journal":{"name":"Journal of Nanoparticle Research","volume":"27 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gold nanoparticles modified porous GaN electrode for electrochemical determination of catechol

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-04-07 DOI: 10.1007/s11051-025-06310-5

Xin Chen, Xiaoyun Li, Yan Zhang, Miaorong Zhang, Jianguo Tang

引用次数: 0

Core–shell structural PLGA nanoparticle of astaxanthin fabricated via micelle template for sustained release in vitro and long-term hepatoprotective effect in vivo

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-04-04 DOI: 10.1007/s11051-025-06301-6

Yuan Zhu, Peiqi Lu, Youwu Liao, Michael Adu-Frimpong, Zhihui Zou, Zhou Jin, Chengwei Wang, Min Peng, Houping Peng, Jingze Xu, Ying Xu, Jiangnan Yu, Ximing Xu

{"title":"Core–shell structural PLGA nanoparticle of astaxanthin fabricated via micelle template for sustained release in vitro and long-term hepatoprotective effect in vivo","authors":"Yuan Zhu, Peiqi Lu, Youwu Liao, Michael Adu-Frimpong, Zhihui Zou, Zhou Jin, Chengwei Wang, Min Peng, Houping Peng, Jingze Xu, Ying Xu, Jiangnan Yu, Ximing Xu","doi":"10.1007/s11051-025-06301-6","DOIUrl":"10.1007/s11051-025-06301-6","url":null,"abstract":"<div><p>This study aimed to prepare core–shell structural PLGA nanoparticles of astaxanthin (ASTA-PLGA@M) via micelle template for sustained release in vitro and long-term hepatoprotective effects in vivo. The morphology, mean particle size, zeta potential, polydispersity index (PDI), and drug loading efficiency of optimized formulation were investigated. Meanwhile, the physicochemical characterizations including X-ray diffraction (XRD) and attenuated total reflectance-Fourier transform infrared (ATR-FTIR) of ASTA-PLGA@M were evaluated to prove the successful encapsulation of astaxanthin. The in vitro release of astaxanthin from ASTA-PLGA@M in four different media was sustained slowly for 120 h. An in vivo release study also demonstrated that ASTA-PLGA@M nanoparticles enhanced oral bioavailability significantly. In addition, the hepatoprotective effects of astaxanthin on oxidative stress (OS) accompanied by apoptosis in acute hepatic damage caused by carbon tetrachloride (CCl<sub>4</sub>) in mice were investigated. ASTA-PLGA@M nanoparticles provide a clear elevating effect on the activity of SOD and inhibit the increase of MDA during acute liver damage caused by CCl4. Moreover, histopathological analysis was conducted to study the long-term hepatoprotective effects of ASTA-PLGA@M for further application of astaxanthin in functional food or clinical use.</p></div>","PeriodicalId":653,"journal":{"name":"Journal of Nanoparticle Research","volume":"27 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143769730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In situ growth of Bi0 and BiOBr on Bi-MOF nanoribbons via chemically bond for boosting the photocatalytic chlortetracycline removal by MOF framework, oxygen vacancies, and mediator-based Z-scheme heterojunction 通过化学键在 Bi-MOF 纳米带上原位生长 Bi0 和 BiOBr，利用 MOF 框架、氧空位和基于介质的 Z 型异质结提高光催化去除金霉素的能力

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-04-03 DOI: 10.1007/s11051-025-06298-y

Ziqi Yang, Fengyan Ma, Yu Zhang, Meihua Ling, Hong Zheng, Yan Yu, Li Li

{"title":"In situ growth of Bi0 and BiOBr on Bi-MOF nanoribbons via chemically bond for boosting the photocatalytic chlortetracycline removal by MOF framework, oxygen vacancies, and mediator-based Z-scheme heterojunction","authors":"Ziqi Yang, Fengyan Ma, Yu Zhang, Meihua Ling, Hong Zheng, Yan Yu, Li Li","doi":"10.1007/s11051-025-06298-y","DOIUrl":"10.1007/s11051-025-06298-y","url":null,"abstract":"<div><p>Design of chemically bonded heterojunction with oxygen vacancies is a serviceable method to facilitate the performance of metal-organic framework (MOFs). Herein, Bi–MOF as bismuth source and frame, chemically bonded close-contact Bi/BiOBr@Bi–MOF heterojunction with intact backbone was successfully developed by two-step easy in situ halogenation and photoreduction of Bi–MOF. The halide amount and photoreduction time regulate the BiOBr and metal Bi loading amount and oxygen defects concentration. Bi/BiOBr@Bi–MOF-5-1 revealed the best photocatalytic efficiency (rate constant) of 97.1% (0.0607 min<sup>−1</sup>) toward chlortetracycline (CTC) after full-spectrum light irradiation for 60 min. The rate constants were 7.2, 2.2, and 2.2 times higher than Bi–MOF, BiOBr, and Bi/BiOBr-5 without MOF structure, respectively, which is owing to the synergistic effect among Bi–MOF framework, OVs, and mediator-based Z-scheme heterojunction by chemically bonding with metal Bi as carrier transfer bridge. This study provides a broad prospect for reasonable design and flexible synthesis of semiconductor/MOF heterojunction with Bi–MOF as nice precursor.</p></div>","PeriodicalId":653,"journal":{"name":"Journal of Nanoparticle Research","volume":"27 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The current use of nanotechnology in the fight against antimicrobial resistance: promising approaches to global health challenge

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-04-02 DOI: 10.1007/s11051-025-06290-6

Gideon Sadikiel Mmbando, Ombeni Ally, Shedrack Reuben Kitimu

{"title":"The current use of nanotechnology in the fight against antimicrobial resistance: promising approaches to global health challenge","authors":"Gideon Sadikiel Mmbando, Ombeni Ally, Shedrack Reuben Kitimu","doi":"10.1007/s11051-025-06290-6","DOIUrl":"10.1007/s11051-025-06290-6","url":null,"abstract":"<div><p>Antimicrobial resistance (AMR) is a worldwide health emergency that requires creative solutions beyond the use of traditional antibiotics. Nanotechnology is a viable substitute that offers fresh methods to fight resilient microbial strains. Unfortunately, there is currently a lack of information available regarding the use of nanotechnology to lessen the AMR challenge worldwide. This review examined the present application of nanotechnology to combat AMR. Different nanomaterials, such as metallic, polymeric, and lipid-based nanoparticles, are highlighted, along with their mechanisms of action, which include rupturing microbial membranes and producing reactive oxygen species. The review also looks at how nanotechnology is used in medical device coatings, drug delivery systems, and improving the effectiveness of current antibiotics. Notwithstanding its potential, issues like environmental effects, regulatory barriers, and safety concerns need to be addressed. Future directions should focus on the need for international collaboration as well as the application of nanotechnology into various antimicrobial tactics like bacteriophage and antimicrobial peptides. This review highlights the significant role that nanotechnology can play in combating AMR.</p></div>","PeriodicalId":653,"journal":{"name":"Journal of Nanoparticle Research","volume":"27 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A DFT study on Ni-Ru core–shell nanoparticles: structure, stability, electronic and magnetic properties 关于 Ni-Ru 核壳纳米粒子的 DFT 研究：结构、稳定性、电子和磁性能

IF 2.1 4区材料科学

Journal of Nanoparticle Research Pub Date : 2025-04-02 DOI: 10.1007/s11051-025-06300-7

Zhengkai Li, Peiyun Li, Zihao Wang, Ruinan Di, Yizhen Wu, Hui Shi, Jishu Li

{"title":"A DFT study on Ni-Ru core–shell nanoparticles: structure, stability, electronic and magnetic properties","authors":"Zhengkai Li, Peiyun Li, Zihao Wang, Ruinan Di, Yizhen Wu, Hui Shi, Jishu Li","doi":"10.1007/s11051-025-06300-7","DOIUrl":"10.1007/s11051-025-06300-7","url":null,"abstract":"<div><p>Monometallic and bimetallic core–shell nanoparticles (MCSNPs and BCSNPs) exhibit excellent stability, electronic, magnetic and the surface chemical properties due to their combination of metallicity and unique core–shell structure. BCSNPs further has synergistic effects. In this study, we systematically studied the geometrical structure, stability, charge transfer, electronic, and magnetic properties of the 13-, 33- and 55-atom Ni-Ru CSNPs using the density functional theory (DFT) calculations. The results show that Ru@Ni BCSNPs with a Ni surface shell are thermodynamically more favorable than the Ni@Ru BCSNPs with a Ru surface shell. Bader charge analysis illustrates that the Ru surface shell of the Ni@Ru BCSNPs displays a negative charge, while the Ni surface shell of the Ru@Ni BCSNPs exhibits a positive charge or approximately electrically neutral. Charge transfer leads to the shift of the d-band centers and further affects the reactivity. Ru@Ni and Ni@Ru BCSNPs have a higher chemical activity than the corresponding Ni or Ru MCSNPs except Ni@Ru<sub>12</sub>. In addition, the Ni@Ru BCSNPs have significantly stronger magnetism when the Ru atoms segregate on surface region. For the MCSNPs of Ru, the size of the particles has an impact on their total magnetic moments.</p></div>","PeriodicalId":653,"journal":{"name":"Journal of Nanoparticle Research","volume":"27 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0