材料科学最新文献

{"title":"Skin-inspired high-strength, adhesive, healable and smart thermoregulation hydrogel sensors for multi-sensing <i>via</i> one-pot PET-RAFT.","authors":"Yifan Yan, Wenqing Wang, Chudan Zhang, Menghan Guo, Liran Zhang, Pengfei Qi, Rui Wang","doi":"10.1039/d5mh01449b","DOIUrl":"https://doi.org/10.1039/d5mh01449b","url":null,"abstract":"<p><p>Currently, smart hydrogel sensors with excellent physicochemical properties and exceptional sensitivity to multiple external stimuli demonstrate considerable potential in various simulations of human skin's functions. In this study, a poly(<i>N</i>-isopropylacrylamide) (PNIPAM)/polypyrrole (PPy) and <i>para</i>-aramid nanofiber (ANF) composite hydrogel (NPAH) was synthesized under ultraviolet irradiation using photoinduced electron transfer reversible addition-fragmentation chain transfer (PET-RAFT) technology. The incorporation of PPy and ANFs resulted in a substantial enhancement of hydrogel mechanical strength, from 0.1069 MPa for the PNIPAM hydrogel (NH) to 0.9190 MPa for the NP₅₈A₄H composite. Furthermore, NP₅₈A₄H exhibited remarkable self-healing (91% tensile strength recovery after 6 h healing) and potent adhesive properties (enhanced contact with a material interface) when adhering to various substrates. The NP₅₈A₄H sensor demonstrated an effective response to temperature (relative resistance change is 1.2% °C^-1) and strain (GF = 1.37) variations, as well as the capacity to detect tension and monitor human movement. Moreover, the photothermal conversion capability of PPy accelerated the lower critical solution temperature (LCST) phase transition of PNIPAM to 31.9 °C and it possessed selectivity in transmitting light in the visible band of solar radiation and could facilitate the \"transparent-opaque\" transition to realize the thermoregulation up to a 9.6 °C temperature difference. The proposed NP₅₈A₄H with excellent integrated properties, especially the high mechanical strength, self-healing, self-adhesiveness and sensitive dual-sensing of temperature and strain, shows great potential for simulation of the human skin to perception of touch, pressure and ambient temperature simultaneously, indicating promising applications in the fields of wearable healthcare, human-machine interfaces, and intelligent thermal management.</p>","PeriodicalId":87,"journal":{"name":"Materials Horizons","volume":" ","pages":""},"PeriodicalIF":10.7,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145342212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease.","authors":"Xiaoyi Zhou, Jia Cong, Rongguang Peng, Dichen Yang, Chenchen Dong, Jing Xie, Jiqi Yan, Jie Kuang, Fubin Li, Leng Siew Yeap, Xiaoyan Xie, Haolong Yin, Rulai Han, Liyun Shen, Yulin Zhou, Guang Ning, Shu Wang, Weiqing Wang, Lei Ye","doi":"10.1002/advs.202508449","DOIUrl":"https://doi.org/10.1002/advs.202508449","url":null,"abstract":"<p><p>Graves' disease (GD) is an autoimmune disorder primarily targeting the thyroid tissue. While major histocompatibility complex (MHC)-dependent B cell activation and thyroid-stimulating hormone receptor (TSHR) autoantibody production are central to GD, the intrathyroidal immune landscape remains largely unexplored. Through single-cell RNA sequencing (scRNA-seq), this work constructed a comprehensive immune cell atlas, revealing dominant IFN-γ-secreting CD4⁺ T cells, expanded T peripheral helper (Tph) cells, CD11c⁺ atypical B cells, and CD8⁺ effector T cells. Notably, stress-surveilling γδ T/NK cells are enriched in GD. Thyroid follicular cells (TFCs) in GD exhibited a stressed phenotype, and in vitro functional assays showed that they promote γδ T cell activation and proliferation. γδ T cells may recruit conventional type 1 dendritic cells (cDC1) via XCL1/XCL2, suggesting a potential link to adaptive immune reorganization. These findings suggest an additional MHC-independent pathway linking TFC stress to autoimmune activation via γδ T cells in GD pathogenesis.</p>","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":"e08449"},"PeriodicalIF":14.1,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145342306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Interface Modification of Electron-Beam-Evaporated NiOx for High-Performance Perovskite Solar Cells.","authors":"Qiyu Shi,Le Wei,Yudong Shao,Jiale Su,Bitao Chen,Disheng Yao,Jilin Wang,Shuyi Mo,Bing Zhou,Guoyuan Zheng,Fei Long","doi":"10.1021/acsami.5c15868","DOIUrl":"https://doi.org/10.1021/acsami.5c15868","url":null,"abstract":"Nickel oxide (NiOx) is considered an ideal hole transport layer (HTL) in inverted perovskite solar cells (PSCs) due to its excellent carrier mobility and low cost. Electron-beam-evaporated NiOx (E-beam-NiOx) exhibits exceptional commercial potential due to its process compatibility. However, there are surface defects in E-beam-NiOx, which are incompatible with perovskite (PVK) and limit its development. In this work, we used [4-(3,6-dimethyl-9H-carbazol-9-yl)butyl]phosphonic acid (Me-4PACz) as a self-assembled monolayer (SAM) and l-α-glycerylphosphorylcholine (GPC) to double modify the buried interface of E-beam-NiOx films. SAM is used to modify interface defects of NiOx, while GPC improves the wetting property and uniformity of the interface. Under the joint modification of SAM and GPC, the interface defects of NiOx films were passivated, and the hole extraction ability of HTL was improved. At the same time, the growth quality of PVK films was improved, and the energy level matching between NiOx and PVK was optimized. After optimization, the small-area (0.0575 cm2) PSCs achieved a champion power conversion efficiency (PCE) of 23.31%, providing an effective strategy and direction for the preparation of high-efficiency PSCs by E-beam-NiOx.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"33 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing DNA and RNA Modification Detection via Nanopore Sequencing.","authors":"Bo He,Yu Fan,Jizhou Liu,Yuting Chen,Jinmin Yang,Huifen Xiang,Jinying Peng,Chengqi Yi","doi":"10.1021/acsnano.5c11784","DOIUrl":"https://doi.org/10.1021/acsnano.5c11784","url":null,"abstract":"DNA/RNA modifications are crucial for biological processes. To understand their regulatory mechanisms, precise mapping and quantification of these modifications are essential. Although next-generation sequencing can detect the location and stoichiometry of modifications, complex treatments are required, hindering efficiency and long-range analysis. In contrast, nanopore sequencing eliminates the need for additional treatment and PCR amplification, thus preserving DNA/RNA modification information. It enables modifications to be identified and quantified directly at the single-molecule level. Therefore, nanopore sequencing facilitates long-read, real-time modification detection, and has gained widespread applications. This perspective introduces the principles of nanopore sequencing, evaluates its strengths/weaknesses, and critically examines its broader real-world applications. To expand the utility of nanopore sequencing further, we discuss the current challenges and suggest future directions.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"56 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Downshifting Luminescence Rare-Earth Nanoparticles for High-Resolution In Vivo Imaging at NIR IIb/c Window.","authors":"Zihang Yu,Qianqian Ran,Mengfei Li,Shihui Wen,Haocheng Gao,Yuezhong Xian,Cuiling Zhang","doi":"10.1021/acs.nanolett.5c04506","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c04506","url":null,"abstract":"Rare-earth nanoparticles (RENPs) operating in the NIR-IIb/c (1600-2000 nm) window hold great promise for bioimaging due to superior spatial resolution and deep tissue penetration. However, achieving high-brightness RENPs with precise emission control remains a significant challenge. Here, we report the rational design of highly Tm3+-doped α-phase core@shell@shell@shell RENPs with a cascade Nd3+-sensitized energy transfer architecture. Optimized RENPs exhibited a quantum yield (QY) of ∼23.5% in the NIR-IIb/c region under 980 nm excitation and achieved a QY of ∼11.3% under 808 nm excitation. Notably, the emission efficiency of highly Tm3+-doped systems (≥8%) is strongly dependent on the thickness of the intermediate Yb3+ shell, while low Tm3+ doping levels (≤4%) show minimal sensitivity to shell thickness. Furthermore, the engineered RENPs exhibit excellent biocompatibility and enable high-contrast deep-tissue vascular imaging in vivo. Our work provides a promising strategy for developing next-generation RENPs tailored for high-performance, noninvasive NIR-IIb/c bioimaging applications.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"138 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural Insights and Functional Dynamics of β-Lactoglobulin Fibrils.","authors":"Rebecca Sternke-Hoffmann,David Rhyner,Genki Terashi,Bilal Muhammad Qureshi,Roland Riek,Jason Greenwald,Daisuke Kihara,Viviane Lutz-Bueno,Jinghui Luo","doi":"10.1021/acs.nanolett.5c04125","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c04125","url":null,"abstract":"Amyloid fibrils from β-lactoglobulin (β-LG), a major whey protein, have attracted interest for nanotechnology due to their biocompatibility, tunable surface chemistry, and ability to bind functional molecules. They serve as scaffolds for metal nanoparticle synthesis, carriers for bioactive compounds, and building blocks for nanomaterials with tailored mechanical and optical properties. However, their dynamic architecture remains incompletely understood, limiting their rational design. Here, we combine cryo-electron microscopy (cryo-EM), small-angle X-ray scattering (SAXS), and molecular dynamics (MD) simulations to investigate β-LG fibrils formed under mildly denaturing conditions. Cryo-EM reveals a monomeric polymorph with a conserved core (Leu1-Ala34) and a disordered \"fuzzy coat\". Flexible domains were modeled and evaluated by MD, identifying one stable conformation (Asn90-Thr97). The ionic strength reduced the coat flexibility and promoted iron binding, suggesting environmental responsiveness. These findings link fibril flexibility to functional potential, offering mechanistic insight into engineering β-LG-based nanomaterials.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"81 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eco-Friendly Nanoarchitectonics for Durable, Self-Cleaning, and Efficient Subambient Radiative Cooling Coatings.","authors":"Yongxian Sun,Junhui He","doi":"10.1021/acsami.5c17341","DOIUrl":"https://doi.org/10.1021/acsami.5c17341","url":null,"abstract":"Passive daytime radiative cooling (PDRC) can contribute to the mitigation of global warming by dissipating heat into outer space without energy consumption. However, challenges persist in developing radiative cooling coatings with high optical performances, environmental adaptability, and multifunction synergy, limiting their practical applications. Here, an eco-friendly spray-coating approach was employed to prepare a Si3N4/Al2O3&SiO2-PCM PDRC coating (SASPRC) based on an innovative design of spectral complementarity and synergy within atmospheric windows. The coating exhibits remarkable solar reflectance of 97.3% and infrared emissivity of 97.7%, achieving an average cooling effect of 8.2 °C below ambient temperature in direct sunlight. By incorporating phase change material (PCM), it delivers a net daily cooling power of 90.03 W m-2, surpassing that without PCM (86.79 W m-2). In addition to the remarkable optical characteristics and exceptional subambient cooling performance, SASPRC also demonstrates stable self-cleaning capability with a water contact angle of 165.3°, superior mechanical robustness, and excellent chemical durability. This rational design presents a viable strategy for developing high-performance radiative coolers that simultaneously address the environmental adaptability, ecological sustainability, and durability of coatings and global warming as the ultimate goal.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"10 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145339041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-Assembled Multifunctional Supraparticle Films for Label-Free Direct SERS Quantitation of Weakly Adsorbing Molecules in Serum.","authors":"Yingrui Zhang,Chunchun Li,Weilong Liu,Yunpeng Huang,Ziwei Ye,Steven E J Bell,Yikai Xu,Xiang Ma","doi":"10.1021/acsami.5c17582","DOIUrl":"https://doi.org/10.1021/acsami.5c17582","url":null,"abstract":"Detecting and quantifying molecular species at trace levels is crucial for understanding fundamental processes in chemistry and biology; however, the complexity of real-life samples renders their direct analysis extremely challenging. Here, we demonstrate a surface-enhanced Raman spectroscopic approach for the direct on-site detection and quantification of trace analytes in real-life samples. The key to our approach is the creation of multifunctional plasmonic films via interfacial self-assembly using colloidal Au@Prussian blue (PB) supraparticles as the functional building block. The supraparticles contain 3-dimensional hot-spots that give rise to strong plasmonic near-field enhancement, while the PB shell acts simultaneously as a molecular sieve and internal standard to induce selective analyte adsorption and to calibrate signal fluctuations. This enables direct identification and quantitation of a range of weakly adsorbing targets in biological and environmental samples using a portable Raman spectrometer, which paves the way for rapid on-site chemical analysis in important applications, including therapeutic drug monitoring and environmental analysis.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"51 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145339045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defect-Dominated Superhydrophobicity: Unraveling Failure Mechanisms for Scalable and Durable Coating Applications.","authors":"Dong Wang,Kangkang Wu,Zhuang Ma,Jiangnan Liu,Yanbo Liu,Xinchun Tian","doi":"10.1021/acsami.5c14911","DOIUrl":"https://doi.org/10.1021/acsami.5c14911","url":null,"abstract":"Superhydrophobic (SH) coatings hold immense potential for industrial applications, yet their widespread adoption has been hindered by fast performance degradation under real-world conditions. This study investigates multiscale defect formation and its performance implications in SiC whisker/silicone resin/PTFE nanoparticle SH coatings, serving as a model for the widely used nanoparticle-based SH composites. By varying PTFE content (1-10 parts), we identified that though micrometer-scale inhomogeneities affected initial wettability, localized regions with low nanoscale roughness (\"defects\") governed long-term SH stability. The optimized formulation (4:2:8 mass ratio) with a uniform nanoscale morphology (Ra = 71.6 nm) exhibited exceptional performance metrics, including a highly stable Cassie state against rainfall flushing (167 mL/s) and waterjet impinging (24.13 m/s, We ≈ 21000), a low ice adhesion strength of 0.8 kPa at -15 °C, and a prolonged plastron stability of >24 days and up to a 96-fold improvement over unoptimized compositions under shear slurry-pot flow (Re ≈ 4200000). These findings provide both fundamental insights into defect-dominated failure mechanisms and practical guidelines for the scalable manufacturing of robust superhydrophobic surfaces.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"20 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145339048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Donor-Acceptor Boron Difluoride Complexes for Bipolar Exciplex Emitters in Organic Light-Emitting Diodes.","authors":"Stepan Kutsiy,Oleksandr Bezvikonnyi,Andrii Hotynchan,Dmytro Volyniuk,Roman Luboradzki,Hanna M Zinchenko,Agnieszka Wisniewska,Pavlo Stakhira,Juozas Vidas Grazulevicius,Mykhaylo A Potopnyk","doi":"10.1021/acsami.5c17456","DOIUrl":"https://doi.org/10.1021/acsami.5c17456","url":null,"abstract":"Four 1,3-thiazole/selenazole-containing boron difluoride complexes with donor-acceptor architectures were designed, synthesized, and thoroughly spectroscopically characterized. X-ray crystallographic analysis revealed that in the solid state the molecules adopt twisted conformations that effectively suppress detrimental π-π stacking. At the same time, numerous intermolecular hydrogen-bonding interactions stabilize the packing, leading to remarkably high solid-state photoluminescence quantum yields of up to 37%. Consistent with these structural features, the dyes exhibit clear aggregation-induced emission enhancement in tetrahydrofuran-water mixtures. Beyond their photophysical properties, the complexes also demonstrate favorable semiconducting behavior. When incorporated as exciplex-forming emitters in organic light-emitting diodes, they enabled efficient device operation with external quantum efficiencies reaching up to 14.9%.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"4 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145339102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}