ACS NanoPub Date : 2026-10-20Epub Date: 2026-10-08DOI: 10.1021/acsnano.6c10025
Chenxu Li, Chen Miao, Du Chen, Qianhai Zhou, Chaohuang Chen, Xunheng Jiang, Jie Hou, Wenhao Wu, Kun Yang, Daohui Lin, Lizhong Zhu, Jiang Xu
{"title":"Arsenic Fingerprint and Microbiome Reconstruction of Rhizosphere-Specific Nanophases in Flooded Paddy Soil","authors":"Chenxu Li, Chen Miao, Du Chen, Qianhai Zhou, Chaohuang Chen, Xunheng Jiang, Jie Hou, Wenhao Wu, Kun Yang, Daohui Lin, Lizhong Zhu, Jiang Xu","doi":"10.1021/acsnano.6c10025","DOIUrl":"10.1021/acsnano.6c10025","url":null,"abstract":"<p>Ubiquitous arsenic (As) nanophasesin soils are metastable dueto the size effect and become readily available to rice under floodedconditions, making substantial contributions to the As pool. Here,the chemical characteristics of As nanophases in the rhizosphere asa hotspot for rice-soil-microbe interactions were fingerprinted ata single-particle resolution, revealing their chemical speciationand interactions with soil microbiota. The initial As particle characteristics(speciation and size) governed bioavailability through distinct transformationpathways mediated by particle-specific elemental associations. Specifically,nanoscale As sulfide and ferrihydrite with adsorbed As resulted ingreater rice uptake than their microscale treatments, whereas nanoscalescorodite exhibited a comparable bioavailability. Analyses at theindividual nanoparticle level revealed that 75–90% of As-bearingparticles were associated with other metals regardless of the initialparticle type. Within the As particles associated with Fe, the Fe-to-Asmass ratios ranged from 27 to 41 despite low co-occurrence probabilities(<30%). The redistributions of As, Fe, and associated elements(e.g., Si/Mn/Zr) observed at the individual particle level alignedwith the metabolic capacity of enriched rhizosphere microbiomes todrive biogeochemical cycling. Such microscale interactions might contributeto As transformation and plant resistance. By resolving metastablenanophase behavior at critical soil-plant interfaces, this work providesmechanistic insights into their dynamic speciation and bioavailabilityduring key agricultural phases, advancing predictive frameworks forAs mobility in agroecosystems.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"20 41","pages":"27795–27806"},"PeriodicalIF":17.3,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149151215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS NanoPub Date : 2026-10-20Epub Date: 2026-10-08DOI: 10.1021/acsnano.6c11994
Xueqian Li, Lei Qiao, Wanrong Wang, Yan Xiong, Le Zhang, Guisong Shan, Qiuting Sun, Tao Ding, Xiaoyan He
{"title":"A Bispecific Nanobridge Derived from Immunogenic Tumor Membranes Restores Dendritic Cell–T Cell Crosstalk for Enhanced Solid Tumor Immunotherapy","authors":"Xueqian Li, Lei Qiao, Wanrong Wang, Yan Xiong, Le Zhang, Guisong Shan, Qiuting Sun, Tao Ding, Xiaoyan He","doi":"10.1021/acsnano.6c11994","DOIUrl":"10.1021/acsnano.6c11994","url":null,"abstract":"<p>In solid tumors, communication between dendritic cells(DCs) andT cells is impaired by poor immune infiltration and lack of physicalcontact, limiting current immunotherapies. Here, we develop a bispecificimmune-bridging platform (NVMB) to address these limitations. NVMBconsists of tumor cell membrane-derived nanovesicles enriched withdamage-associated molecular patterns (DAMPs) that activate DCs andsupport T-cell responses. The vesicle surface is further functionalizedwith two aptamers targeting DCs and CD8<sup>+</sup> T cells, respectively,thereby enhancing their spatial proximity and facilitating functionalDC–T cell interactions. This biomimetic design combines colloidalstability with programmable surface functionalization. Mechanistically,NVMB promotes DC–T interactions and enhances activation-associatedphenotypes in both cell populations. In multiple immunocompetent mousetumor models, NVMB suppresses tumor growth, increases intratumoralaccumulation of mature DCs and activated CD8<sup>+</sup> T cells,and reshapes the tumor microenvironment transcriptome toward enhancedantitumor immune responses. Moreover, combination with immune checkpointblockade (ICB) further improves antitumor efficacy compared with eithermonotherapy, supporting the potential of NVMB as a complementary strategyfor enhancing ICB responses. In patient-derived cocultures of circulatingtumor cells (CTCs) and autologous peripheral blood mononuclear cells(PBMCs), NVMB enhances T-cell-mediated clearance of CTCs. These findingssupport NVMB as a stable and modular nanoplatform that integratesimmunogenic signaling with immune-cell spatial coordination, providinga promising strategy for strengthening antitumor immunity and improvingthe efficacy of existing immunotherapies.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"20 41","pages":"27890–27907"},"PeriodicalIF":17.3,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149151248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS NanoPub Date : 2026-10-20Epub Date: 2026-10-08DOI: 10.1021/acsnano.6c10075
Kaiyue Peng, Chieh Tsao, Hendrik Utzat, Eran Rabani
{"title":"Selective Biexciton Generation under Energy-Time Entangled Quantum Light in Quantum Dots","authors":"Kaiyue Peng, Chieh Tsao, Hendrik Utzat, Eran Rabani","doi":"10.1021/acsnano.6c10075","DOIUrl":"10.1021/acsnano.6c10075","url":null,"abstract":"<p>Quantumlight provides opportunities for controllingmultiphotonabsorption beyond the classical limits. Here, we investigate biexcitongeneration in nanocrystal quantum dots driven by energy-time-entangledphoton pairs generated via spontaneous parametric downconversion.We show that frequency–time correlations between pairs of photonsincrease the population of biexcitons over excitons, thereby lendingspecificity to the excitation of many-body states. By employing athree-level model, we demonstrate that biexciton generation dependsnontrivially on the photon entanglement time and pump bandwidth. Wefind that maximizing efficiency requires an optimally shaped entangledphoton field rather than simply scaling parameters for a monotonicimprovement. Extending to a realistic CdSe/CdS core–shell quantumdot containing many excitonic states coupled to the quantum field,we demonstrate that increasing the biphoton arrival-time entanglement(closer arrival time) enhances constructive pathway interference andexpands accessible excitation channels while preserving better energy-conservationin excitation than classical light when generating biexcitons. Furthermore,tuning the time-correlation properties enables selective excitationof closely spaced biexciton states. These results establish entangledphotons as tools for selective excitation and control of higher-orderexcited states in quantum-confined systems.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"20 41","pages":"27807–27817"},"PeriodicalIF":17.3,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149151249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bing-Xuan Shi,Timo Weintraut,Thomas Demuth,Sabrina Sicolo,Boburmirzo Juraev,Sebastian L. Benz,Burak Aktekin,Kilian Vettori,Yuriy Yusim,Karsten Albe,Kerstin Volz,Anja Henss,Felix H. Richter
{"title":"Nanoscale Surface Modification of Li6PS5Cl Particles To Stabilize Lithium Solid-State Battery Interfaces","authors":"Bing-Xuan Shi,Timo Weintraut,Thomas Demuth,Sabrina Sicolo,Boburmirzo Juraev,Sebastian L. Benz,Burak Aktekin,Kilian Vettori,Yuriy Yusim,Karsten Albe,Kerstin Volz,Anja Henss,Felix H. Richter","doi":"10.1021/acsami.6c13206","DOIUrl":"https://doi.org/10.1021/acsami.6c13206","url":null,"abstract":"Thiophosphate solid electrolytes (SEs) may enable the energy storage transformation to solid-state batteries, but interface instability and lithium dendrite formation significantly limit their practical application. To address these challenges, we present a scalable N-methyl-2-pyrrolidone (NMP) surface modification to boost the performance of Li6PS5Cl (LPSCl) SE. This NMP surface modification on LPSCl improves electrochemical stability of the SE in the positive electrode and stabilizes the lithium-metal interface when used as a separator. When used as SE in positive electrode and separator, the modified LPSCl (m-LPSCl) increases the first cycle discharge capacity by ∼11 mAh g–1 at a current density of 0.21 mA cm–2 and improves capacity retention by 10% over pristine LPSCl (p-LPSCl) after 100 cycles. As a separator, higher critical current density is reached with m-LPSCl (1.6 mA cm–2) than with p-LPSCl (1 mA cm–2) before shorting of the cell. For the pair of single-crystal LiNiO2 (LNO)-positive electrode and lithium metal-negative electrode, m-LPSCl enables over 100 stable cycles, significantly outperforming the cell with p-LPSCl, which shorts after 25 cycles. Overall, this study introduces a scalable method for modifying LPSCl by solvent treatment that improves positive electrode performance and increases stability of the lithium metal-negative electrode interface.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"14 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fabrication of Microwave-Responsive Confined NaCl in Polydopamine","authors":"Guxia Wang,Yingdong Wei,Mimi Xu,Dan Li,Shengwei Guo","doi":"10.1021/acsami.6c14835","DOIUrl":"https://doi.org/10.1021/acsami.6c14835","url":null,"abstract":"Microwave-responsive nanoparticles hold promising applications in microwave thermal therapy and electromagnetic shielding; however, fabricating nanoparticles with high energy conversion efficiency remains challenging. This study leverages the catechol and amino groups in polydopamine (PDA) molecules to achieve simultaneous loading of Na+ and Cl– ions. Through potassium persulfate oxidation to protonate PDA's amino groups for Cl– adsorption, followed by Tris-base pH adjustment to facilitate Na+ binding with catechol groups, we successfully confined sodium chloride (NaCl) within PDA via layer-by-layer assembly, creating highly efficient NaCl@PDA microwave-responsive nanoparticles. Systematic investigation revealed that toluene and potassium persulfate dosage significantly influenced nanoparticle size, with 2 g of potassium persulfate yielding uniform spherical nanoparticles (≈149 nm diameter) with well-defined morphology. Through systematic optimization of the NaCl content, we found that a loading of 36.0 wt % endowed the nanoparticles with exceptional thermal conversion performance under ultralow-power microwave irradiation (2 W, 2450 MHz), achieving 53 °C within 600 s demonstrating 1.7-fold and 1.4-fold faster heating rates compared to physiological saline and pure PDA nanoparticles, respectively. The synthesized nanoparticles exhibit superior microwave responsiveness, showing great potential for applications in microwave thermal therapy and stealth coating technologies.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"11 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuying Wang,Jiayao Wulan,Qiliang Huang,Pengyue Zhao,Chong Cao,Yuqing Lin,Lidong Cao
{"title":"Hydrogel Microneedle-Enabled In Situ Monitoring of Leaf Nitric Oxide for Evaluating NO Nanoprodrug-Mediated Salt Stress Alleviation in Maize","authors":"Yuying Wang,Jiayao Wulan,Qiliang Huang,Pengyue Zhao,Chong Cao,Yuqing Lin,Lidong Cao","doi":"10.1021/acsami.6c16130","DOIUrl":"https://doi.org/10.1021/acsami.6c16130","url":null,"abstract":"Chemical signals in living plants are spatially confined, rapidly consumed, and strongly dependent on the delivery history of exogenous regulators, creating a need for bioelectronic interfaces that can interrogate molecular dynamics directly within intact tissues. Here, we integrate a nitric oxide (NO) nanoprodrug with a conductive hydrogel microneedle platform to connect controlled molecular delivery, in planta electrochemical readout, and downstream biological responses in living maize. The working electrode comprises a poly(vinyl alcohol)/aramid nanofiber (PVA/ANF) hydrogel containing FeMo-N/C and an MXene conductive network. The hydrated microneedle architecture provides tissue-conformal contact and analyte transport, FeMo-N/C enhances the NO-associated electrochemical response, and MXene improves interfacial charge transfer. The resulting platform responds to NO from 1 nM to 100 μM with a detection limit of 0.3 nM and discriminates NO from representative electroactive plant interferents. Chitosan nanoparticles containing S-nitroso-mercaptosuccinic acid were used to moderate NO release, and the microneedle interface resolved treatment-dependent leaf signals over 7 days under salt stress. Signal attenuation by the NO scavenger cPTIO supported the NO-related origin of the electrochemical response. The time-resolved readout was accompanied by improved growth, reduced lipid peroxidation, changes in osmotic and antioxidant responses, and altered expression of stress-responsive genes. This delivery–bioelectronics–analysis framework provides a materials-based strategy for evaluating reactive nanoprodrugs and interrogating transient chemical signaling in living plants.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"63 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Magnetic Phase Diagram of Cr2Te3: The Hidden Role of Layer Stacking","authors":"Cyriack Jego,Thierry Sauvage,Nicolas Gauthier,Quentin Guillet,Jean-François Jacquot,Isabelle Gomes de Moraes,Damien Caliste,Pascal Pochet,Denis Jalabert,Hanako Okuno,Thomas Olsen,Alain Marty,Matthieu Jamet","doi":"10.1021/acs.nanolett.6c03322","DOIUrl":"https://doi.org/10.1021/acs.nanolett.6c03322","url":null,"abstract":"Using two-dimensional (2D) van der Waals (vdW) ferromagnets in spintronic devices can enhance their performance through well-controlled vdW interfaces and reduced power consumption. Cr2Te3 appears as a promising candidate because of its strong perpendicular magnetic anisotropy, but the Curie temperature is limited to 180 K. In this work, we use annealing in air to uncover the magnetic phase diagram of Cr2Te3. We correlate magnetic properties with layer stacking and the interlayer distance; both depend strongly on the annealing temperature. In particular, disorder in layer stacking plays a key role in the magnetic properties of Cr2Te3 and more generally of vdW ferromagnets. By annealing at 375 °C, we can eventually raise the Tc of Cr2Te3 up to 303 K in the epitaxial Cr2Te3/WSe2 vdW heterostructure with in-plane magnetic anisotropy. This work provides a simple method to control the magnetic properties of 2D ferromagnets and incorporate them into spintronics devices.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"234 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sn/Cl Co-Doped ZnO Cathode Interfacial Layer for High-Performance Organic Photodetectors","authors":"Zhihuan Miao,Muyi Fu,Runze Zhou,Kaiming Zhu,Yao Xu,Zhikun Yu,Kai Zhang","doi":"10.1021/acsami.6c15059","DOIUrl":"https://doi.org/10.1021/acsami.6c15059","url":null,"abstract":"Organic photodetectors (OPDs) hold significant promise for applications spanning medical monitoring, bioimaging and night vision due to their unique advantages, such as flexibility, light weight, and potential for large-area fabrication. Nevertheless, the dark current density (Jd) of OPDs exhibits a pronounced increase under applied reverse bias, which consequently degrades the specific detectivity (D*). To tackle this challenge, this work proposes an interface engineering strategy based on Sn/Cl co-doped ZnO (SCZO). The doping effectively reduces oxygen defects in ZnO, causing the valence band maximum (VBM) to shift downward, thereby suppressing hole injection under bias and reducing Jd. Experiments show that the SCZO-based device exhibits a Jd of 4.05 × 10–11 A cm–2 at –0.1 V, nearly one order of magnitude lower than that of the control device (4.07 × 10–10 A cm–2). Notably, the SCZO-based OPD enables real-time and accurate monitoring of human heart rate, demonstrating its considerable potential for health-monitoring applications. Furthermore, OPDs incorporating the SCZO interface exhibit excellent imaging performance under 820 nm illumination. These findings underscore the significant potential of SCZO-based OPDs for flexible, wearable health monitoring and near-infrared imaging applications.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"10 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS NanoPub Date : 2026-10-20DOI: 10.1021/acsnano.6c11666
Aidan Delgado,Carolin Dusold,James Wu,Jingwei Jiang,Christina M. Dadich,Adam Cronin,Steven G. Louie,Felix R. Fischer
{"title":"Low Energy Excitations in a [4]Triangulene Honeycomb Antiferromagnet","authors":"Aidan Delgado,Carolin Dusold,James Wu,Jingwei Jiang,Christina M. Dadich,Adam Cronin,Steven G. Louie,Felix R. Fischer","doi":"10.1021/acsnano.6c11666","DOIUrl":"https://doi.org/10.1021/acsnano.6c11666","url":null,"abstract":"Carbon-based synthetic lattices offer a versatile platform for the realization and control of correlated quantum effects at the nanoscale. Advances in on-surface synthesis have enabled the fabrication of increasingly complex molecular frameworks, providing opportunities for the exploration and engineering of custom tailored electronic and magnetic phases. Here, we report the design, on-surface synthesis, and characterization of a two-dimensional (2D) covalent organic framework (COF) assembled from D3h symmetric S = 3/2 [4]triangulene building blocks arranged in a honeycomb structure. Combined scanning probe microscopy and spectroscopy, corroborated by first-principles density functional theory (DFT) and GW calculations, establish an antiferromagnetic (AFM) insulating ground state. Low energy spectroscopy resolves spin excitations in both one-dimensional (1D) chains and extended 2D networks, providing direct insight into the emergent spin dynamics and establishing a modular platform to explore quantum magnetism in a π-conjugated organic system.","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"13 1","pages":""},"PeriodicalIF":17.1,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}