Elsevier最新文献

{"title":"Corrigendum to \"Spatial confinement-enhanced CHA system based on tetrahedral DNA nanostructures for sensitive in situ mRNA analysis\" [Talanta 306 (2026) 129764].","authors":"Yujie Wang, Tongtong Pan, Mengru Li, Xiaoyan Dai, Siyong Zhang, Hongmei Fu, Ying Chen, Chang Xue, Zhifa Shen, Liang Xu","doi":"10.1016/j.talanta.2026.130096","DOIUrl":"10.1016/j.talanta.2026.130096","url":null,"abstract":"","PeriodicalId":435,"journal":{"name":"Talanta","volume":" ","pages":"130096"},"PeriodicalIF":6.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148215804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paternal versus maternal depressive symptoms and child internalizing/externalizing problems: a comparative threshold analysis.","authors":"Minna Liu, Hongli Sun, Jiahua Liu, Jie Mi","doi":"10.1016/j.jad.2026.122419","DOIUrl":"10.1016/j.jad.2026.122419","url":null,"abstract":"<p><strong>Background: </strong>Parental depression is a well-established risk factor for child psychopathology, yet most studies focus on mothers. Whether nonlinear patterns with thresholds exist, especially for fathers, remains unclear. This study examines these associations and identified optimal thresholds comparing mothers and fathers.</p><p><strong>Methods: </strong>This cross-sectional study included 21,366 parents (16,258 mothers and 5108 fathers) of children aged 3-6 years in western China. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CESD). Child internalizing and externalizing problems were measured with the Strengths and Difficulties Questionnaire (SDQ). Piecewise logistic regression with grid search identified thresholds, adjusting for demographic and socioeconomic covariates.</p><p><strong>Results: </strong>Higher CES-D scores were associated with increased odds of child problems (all P < 0.001). The gender by CES-D interaction was significant for externalizing problems (P = 0.019), indicating a stronger association in fathers. For internalizing problems, the optimal threshold was a CES-D score of 17 for both mothers and fathers. For externalizing problems, the threshold was lower in fathers (16) than in mothers (21). Below these thresholds, each one-point increase in CES-D score was associated with 10-16% higher odds of child problems. Above the thresholds, the associations were attenuated. Piecewise models fitted significantly better than linear models (all P < 0.001).</p><p><strong>Conclusions: </strong>Fathers' depressive symptoms were associated with child externalizing problems at a lower severity level compared with mothers, suggesting that screening for paternal depression even at subclinical levels may help identify families at elevated risk. The identified thresholds may help generate hypotheses for future longitudinal and clinical validation studies.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"122419"},"PeriodicalIF":5.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148813165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychodynamic characteristics associated with DSM-5 somatic symptom disorder in patients with persistent physical symptoms: A cross-sectional analysis.","authors":"Sabrina Berens, Sebastian Dietsche, Chrysovalandis Schwale, Johannes C Ehrenthal, Jonas Tesarz, Rainer Schaefert","doi":"10.1016/j.jad.2026.122375","DOIUrl":"10.1016/j.jad.2026.122375","url":null,"abstract":"<p><strong>Background: </strong>Persistent physical symptoms (PPS) are distressing bodily complaints that persist irrespective of underlying etiology and represent a descriptive, transdiagnostic umbrella concept. Psychodynamic models highlight attachment-related affect-regulation difficulties and impaired mentalizing as potentially relevant mechanisms. With the introduction of DSM-5, somatic symptom disorder (SSD) was conceptualized as a subgroup within the PPS spectrum characterized by excessive symptom-related thoughts, feelings, and behaviors, requiring re-evaluation of previous psychodynamic findings.</p><p><strong>Methods: </strong>This cross-sectional study (Germany, 02-12/2017) compared three matched groups (96 PPS patients with a positive SSD screen, 96 PPS patients without a positive SSD screen, and 96 healthy controls (HC)) using standardized self-report measures of psychological burden, adverse childhood experiences, attachment, mentalizing, and personality functioning. Symptom-related thoughts, feelings, and behaviors were additionally examined dimensionally across the PPS spectrum.</p><p><strong>Results: </strong>Compared with patients with PPS without SSD, those screening positive for SSD showed higher attachment anxiety (η² = 0.054; small-to-moderate effect), greater impairments in mentalizing (η² = 0.047; small-to-moderate effect), and personality functioning (η² = 0.069; moderate effect). Both PPS groups reported higher attachment avoidance than HC, whereas elevated attachment anxiety was specific to the SSD group. Across the PPS spectrum, psychodynamic impairments were most pronounced at high levels of symptom-related thoughts, feelings, and behaviors.</p><p><strong>Conclusions: </strong>Among patients with PPS, those screening positive for SSD showed higher attachment anxiety and impairments in mentalizing and personality functioning. These psychodynamic impairments appear to show a threshold pattern at high levels of symptom-related thoughts, feelings, and behaviors, suggesting that assessment of psychodynamic characteristics may help identify patients for more targeted interventions.</p><p><strong>Trial registry: </strong>[DRKS00011685].</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"122375"},"PeriodicalIF":5.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heritability of postpartum depression in female twin pairs: A Danish population-based cohort study.","authors":"Mette Bliddal, Sofie Egsgaard, Carolyn E Cesta, Dorthe A Pedersen, Sören Möller, Kaare Christensen, Trine Munk-Olsen","doi":"10.1016/j.jad.2026.122432","DOIUrl":"10.1016/j.jad.2026.122432","url":null,"abstract":"<p><strong>Objective: </strong>Postpartum depression (PPD) is a common but severe psychiatric condition following childbirth, and its underlying causes and degree of heritability remain unclear. We aimed to examine the heritability of PPD among parous female twin pairs.</p><p><strong>Method: </strong>We linked data from the Danish Twin Register to nationwide health registers. Zygosity was defined as monozygotic (MZ) or dizygotic (DZ) based on validated questionnaires, and PPD was defined using hospital diagnosis of depressive disorders or filled prescriptions of antidepressant medication during the first year postpartum. We used a classic twin design to estimate genetic variance in PPD liability, applying probandwise concordance rates, tetrachoric correlations, and biometric modeling to decompose phenotypic variance into genetic and environmental components.</p><p><strong>Results: </strong>The study included 10,418 female twins (5209 pairs) born from January 1949 to December 2000. There were 68 PPD-discordant and 10 PPD-concordant MZ pairs and 85 PPD-discordant and 5 PPD-concordant DZ pairs. The probandwise concordance rates were 0.22 (95% confidence interval (CI) 0.13-0.35) for MZ twins and 0.11 (95% CI 0.05-0.23) for DZ twins. The heritability (additive genetic effect) of PPD was 0.60 (95% CI 0.46-0.75) with a corresponding unique environment variance of 0.40 (95% CI 0.25-0.54).</p><p><strong>Conclusion: </strong>The results indicate that heritability explains a substantial part of PPD risk. This knowledge is pivotal to understanding the role of genetics and to reducing the stigma of PPD among new mothers. However, the contribution of environmental and other possible modifiable factors emphasizes the importance of targeted prevention initiatives.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"122432"},"PeriodicalIF":5.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148828588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stakeholders’ expectations versus standard setters’ outcome about crypto assets accounting: A PLS-SEM analysis","authors":"Adriana Tiron-Tudor,&nbsp;Stefania Mierlita,&nbsp;Cristina Stefanescu","doi":"10.1016/j.accinf.2026.100772","DOIUrl":"10.1016/j.accinf.2026.100772","url":null,"abstract":"<div><div>This research aims to explore the interplay between stakeholders and the US accounting standard setter on the accounting treatment of crypto assets. We applied the beliefs-actions-outcomes (BAO) model to capture stakeholders’ expectations, expressed in their comment letters in response to the Financial Accounting Standards Board’s Exposure Draft (FASB’s ED) on Topic 350, and to assess their expectations’ reflection in the revised version of the standard. We analysed the relationship between stakeholders’ beliefs, proposed actions, and the final standard’s outcome using PLS-SEM (partial least squares structural equation modelling) in SmartPLS. Furthermore, we examine whether feedback from the accountancy profession, a significant stakeholder group in this process, acts as a moderator of the belief-action relationship. The results confirm that the beliefs significantly influence the proposed actions but have a minimal impact on the outcome, with a small number of suggestions for improvement being integrated. The involvement of the accountancy profession moderated the relationship between beliefs and actions, only for the scope and measurement categories, reflecting their specialised knowledge and technical expertise. Through empirical results, current research contributes to the debate on crypto asset regulation by examining stakeholders’ expectations and how their participation has influenced this regulatory field, emphasising the standard-setting body’s responsiveness to their input. The study offers theoretical and practical insights into the interplay between stakeholders’ beliefs, their proposed actions, and the development of crypto accounting regulation (the outcome).</div></div>","PeriodicalId":47170,"journal":{"name":"International Journal of Accounting Information Systems","volume":"57 ","pages":"Article 100772"},"PeriodicalIF":6.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146160150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep without borders starts here: Principles and pathways for sleep health promotion","authors":"Reut Gruber ,&nbsp;Winfried Randerath","doi":"10.1016/j.sleepx.2025.100172","DOIUrl":"10.1016/j.sleepx.2025.100172","url":null,"abstract":"","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"11 ","pages":"Article 100172"},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novelty seeking and rapid symptom improvement across active and sham accelerated iTBS conditions: A pooled individual-patient data analysis.","authors":"Cecilia Chiarenza, Beatriz Araújo Cavendish, Deng Mao, Yichen Zhang, Kevin La Monica, Guo-Rong Wu, Sara De Witte, Paula Horczak, Cisse Geleyn, Maria Salvina Signorelli, Carmen Concerto, Laís Boralli Razza, Chris Baeken","doi":"10.1016/j.jad.2026.122406","DOIUrl":"10.1016/j.jad.2026.122406","url":null,"abstract":"<p><strong>Introduction: </strong>Major depressive disorder (MDD) is highly prevalent and often treatment-resistant. Accelerated intermittent theta burst stimulation (aiTBS) is a promising intervention for treatment-resistant depression (TRD), though outcomes vary. Personality traits have been examined in relation to rTMS outcomes, yet their role in aiTBS remains underexplored. This pooled individual-patient-data analysis of two randomized, sham-controlled trials examined associations between baseline Temperament and Character Inventory (TCI) traits and one-week symptom change, and whether they differed by condition.</p><p><strong>Methods: </strong>The left dorsolateral prefrontal cortex was targeted for 20 sessions over 4 days. Personality was assessed with the TCI, depression severity with the 17-item Hamilton Depression Rating Scale (HDRS-17). TCI-symptom-change associations were examined with a robust linear mixed-effects model, adjusting for age, gender, repeated measurements, and study membership.</p><p><strong>Results: </strong>104 participants were included (M/F 45/59; mean age 40.9 ± 12.7; active/sham 50/54). The model yielded a Time × Novelty Seeking interaction (β = -1.70, p = 0.021): higher baseline Novelty Seeking was associated with faster symptom reduction, without a between-arm difference. However, the interaction did not survive Holm correction across 14 trait-interaction tests (adjusted p = 0.294) and is therefore exploratory. No other interaction reached the uncorrected threshold.</p><p><strong>Conclusions: </strong>Higher baseline Novelty Seeking showed a nominal association with faster symptom reduction, without a difference between active and sham conditions. Because it did not survive multiplicity correction and was not reproduced in within-arm analyses, it is preliminary and may reflect contextual or nonspecific processes. Independent replication is required before temperament assessment can be clinically informative.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"122406"},"PeriodicalIF":5.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient analysis of n-alkanes by high-pressure photoionization-induced NO₂⁺ chemical ionization time-of-flight mass spectrometry.","authors":"Xuefeng Sun, Bo Li, Guolong Wang, Yifan Ding, Anshan Xiao","doi":"10.1016/j.talanta.2026.130161","DOIUrl":"10.1016/j.talanta.2026.130161","url":null,"abstract":"<p><p>Normal alkanes (n-alkanes) are important constituents of anthropogenic volatile organic compounds (VOCs) and petroleum products. Their rapid, sensitive, and selective detection is crucial for environmental monitoring and industrial process control. Conventional GC-based methods are time-consuming, while existing direct MS techniques often suffer from low sensitivity or severe fragmentation. In this study, we introduce a novel high-pressure photon ionization-NO₂⁺ chemical ionization time-of-flight mass spectrometry (HPPI-PNO₂CI-TOFMS) platform for the efficient analysis of C₄-C₁₁ n-alkanes. A vacuum ultraviolet (VUV) lamp is used to photoionize NO₂ reagent gas at pressures of approximately 600-700 Pa, generating NO₂⁺ reactant ions that undergo hydride-transfer reactions with n-alkanes to produce predominantly [M - H]⁺ ions with minimal fragmentation, with [M - H]⁺ branching ratios exceeding 90-96% for C₄-C₁₁ alkanes. Under optimized conditions (1 V, ∼660 Pa), limits of detection (LODs) reach ∼8.6 ppbv for n-butane and 0.21-2.57 ppbv for C₅-C₁₁ n-alkanes with 5 s integration times. The method was successfully applied to refinery gas samples, facilitating the selective and rapid quantification of n-alkanes against complex VOC backgrounds. However, this method does not detect C₁-C₃ n-alkanes and cannot distinguish n-alkanes from their branched or cyclic isomers by mass spectrometry alone. Nevertheless, the HPPI-PNO₂CI-TOFMS thus provides a robust, real-time analytical tool characterized by high sensitivity, clean spectra, and minimal fragmentation, making it well suitable for environmental monitoring, emissions tracking, and industrial process control.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"310 ","pages":"130161"},"PeriodicalIF":6.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148300593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¹O₂-driven photobleaching pathways of xanthene dyes: A comparative study via LC-QTOF-MS/MS analysis and FT-IR spectroscopy.","authors":"Simone Bassini, Victoria Beltran, Nick Sleegers, Andrea Marchetti, Koen Janssens, Alexander L N van Nuijs, Karolien De Wael","doi":"10.1016/j.talanta.2026.130176","DOIUrl":"10.1016/j.talanta.2026.130176","url":null,"abstract":"<p><p>Singlet oxygen (¹O₂)-driven photodegradation is a key factor that controls the stability of xanthene dyes and a mechanism of their photobleaching is still lacking. Here, we report a comparative photodegradation study of five xanthene dyes (i.e., erythrosin B, eosin Y, fluorescein, phloxine B and rose bengal) under illumination conditions maximizing ¹O₂ generation. Time-resolved degradation was analyzed mainly by LC-QTOF-MS and FTIR spectroscopy, enabling identification of major intermediates and allowing the description of a general degradation mechanism. Despite the different molecular structures, only two different pathways were identified: i) all dyes were consecutively oxidized, yielding a major product with partial cleavage of the tricyclic xanthene core; ii) dyes lacking chlorine substitution on the peripheral benzoate ring presented a faster route, leading to complete chromophore breakdown and formation of low molecular weight oxidation products. These results show a relationship between structure and degradation pathway and provide important insights relevant to design, lifetime and conservation of xanthene-based dyes.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"310 ","pages":"130176"},"PeriodicalIF":6.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustained cognitive and functional effects of pro-cognitive interventions for bipolar disorder: A systematic review of randomised controlled trials.","authors":"Michail Kalfas, Anna Tröger, Elliot Hampsey, Rebecca Strawbridge, Kamilla W Miskowiak, Sameer Jauhar, Allan H Young, Dimosthenis Tsapekos","doi":"10.1016/j.jad.2026.122390","DOIUrl":"10.1016/j.jad.2026.122390","url":null,"abstract":"<p><p>A substantial proportion of individuals with bipolar disorder (BD) experience considerable cognitive deficits. Existing systematic reviews have evaluated the efficacy of pro-cognitive interventions in BD, but have not established whether any cognitive benefits translate into functional improvements, with evidence for sustained functional effects remaining limited. A systematic search was conducted on MEDLINE, EMBASE, PsycINFO and Cochrane Library from inception until 21 May 2026. Eligible studies were randomised controlled trials (RCTs) in BD reporting cognitive or functional outcomes at three or more months following a pro-cognitive intervention, or examining the translation of cognitive benefits into improvements in functional outcomes at any timepoint. Seven unique RCTs plus three secondary analyses of these trials (n = 615) met the inclusion criteria. Approximately 13% (7/55) of RCTs identified in the search of pro-cognitive interventions in adult BD assessed cognitive or functional outcomes at least 3 months after treatment end. Of the seven unique RCTs, most evaluated cognitive remediation (CR; k = 4). The average follow-up length was 4 months (range: 3-6 months). Three of the four RCTs examining CR reported cognitive benefits at 3 to 6 months, whereas only one CR RCT found consistent functional effects at 3 months. Evidence on the translation of cognitive benefits to functional improvements is scarce and inconsistent. Most trials examining pro-cognitive interventions do not examine whether potential benefits are sustained or whether they translate into improvements in real-world functioning. CR appears to be a promising intervention for achieving durable cognitive gains in BD, although evidence for sustained effects of other interventions is limited.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"414 ","pages":"122390"},"PeriodicalIF":5.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}