Elsevier最新文献

{"title":"Posttraumatic stress disorder and depression trends from 2001 to 2021 among post-9/11 veterans in the U.S. Millennium Cohort Study.","authors":"Judith Harbertson, Cynthia A LeardMann, Toni Rose T Geronimo-Hara, Isabel G Jacobson, Felicia R Carey, Crystal L Lewis, Neika Sharifian, Sheila F Castañeda, Erin L Richard, Nicole Riedel, Aaron I Schneiderman, Edward J Boyko, Rudolph P Rull","doi":"10.1016/j.jad.2026.122338","DOIUrl":"10.1016/j.jad.2026.122338","url":null,"abstract":"<p><p>Approximately one in five veterans may develop a mental health condition, though longitudinal prevalence estimates among post-9/11 veterans are limited. This study examined two decades (2001-21) of posttraumatic stress disorder (PTSD) and depression data from the Millennium Cohort Study. Eligible participants were actively serving at baseline and separated before the 2019-21 follow-up survey (n = 133,575). Probable PTSD (PTSD Checklist) and depression (Patient Health Questionnaire) were assessed. Age- and sex-standardized prevalence estimates for PTSD, depression, and co-occurring PTSD/depression (a four-level, mutually exclusive variable) were calculated for six time points. PTSD increased approximately five-fold (5.2 to 25.2 cases/100 persons) and depression four-fold (3.6 to 15.5 cases/100 persons). For the co-occurring PTSD/depression outcome, a two-fold increase was observed for depression only (1.5 to 2.7 cases/100 persons), while increases for PTSD only (3.1 to 12.4 cases/100 persons), and comorbid PTSD/depression (2.0 to 12.7 cases/100 persons) were four- and six-fold, respectively. In this population-based study, prevalence estimates of PTSD and depression increased over time, with larger increases attributable to PTSD and co-occurring PTSD/depression. These pronounced increases in prevalence estimates warrant consideration for expansion of mental health screening and treatment services among post-9/11 veterans.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"122338"},"PeriodicalIF":5.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging brain structures and adolescent depression and anxiety symptoms: A symptom-oriented approach.","authors":"Qingwen Ding, Divyangana Rakesh, Siya Peng, Xinying Li, Sarah Whittle","doi":"10.1016/j.jad.2026.122396","DOIUrl":"10.1016/j.jad.2026.122396","url":null,"abstract":"<p><strong>Background: </strong>Anxiety and depression show substantial heterogeneity and often emerge in adolescence. However, their brain structural associations from a symptom-oriented perspective remain unclear. This study investigated the symptom structures of adolescent anxiety and depression and identified key brain regions linking brain structure to symptoms.</p><p><strong>Methods: </strong>A total of 1568 adolescents with elevated depressive symptoms and 413 adolescents with elevated anxiety symptoms were identified from the Adolescent Brain Cognitive Development study. Participants completed symptom assessments and underwent Magnetic Resonance Imaging scanning. A total of ten symptom-only networks and symptom-brain networks were constructed to identify the central symptoms and the key brain structure associated with depression and anxiety symptoms.</p><p><strong>Results: </strong>In the symptom-only networks, concentration difficulties emerged as the shared central symptom, while self-hatred and irritability were the unique central symptoms for depression and anxiety, respectively. In the symptom-brain networks, left- and right-pallidum volumes exhibited the highest bridge centrality in connection with depressive symptoms, whereas left-nucleus accumbens volume showed the highest bridge centrality in connection with anxiety symptoms. Cortical structures showed sparse connections with both depressive and anxiety symptoms.</p><p><strong>Conclusion: </strong>Our findings highlight the pallidum and nucleus accumbens as key brain regions linking brain structure to adolescent depressive and anxiety symptoms. These results provide insights into the neural mechanisms of depression and anxiety from a symptom-oriented perspective and may inform targeted interventions for at-risk youth.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"414 ","pages":"122396"},"PeriodicalIF":5.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden of health comorbidities and associated health care costs in the Australian Genetics of Depression Study using the medication-based Rx-Risk Comorbidity Index.","authors":"Penelope A Lind, Ian B Hickie, Enda M Byrne, Nicholas G Martin, Sarah E Medland","doi":"10.1016/j.jad.2026.122397","DOIUrl":"10.1016/j.jad.2026.122397","url":null,"abstract":"<p><p>Depression is associated with substantial multimorbidity and elevated healthcare utilization. This study characterised treated comorbidities and healthcare costs in participants of the Australian Genetics of Depression Study (AGDS) using pharmaceutical claims data. Linked Pharmaceutical Benefits Scheme (PBS) records from 01/07/2013-31/12/2017 were available for 15,890 AGDS participants. Forty-six chronic conditions were inferred using the validated pharmacy-based Rx-Risk Comorbidity Index based on Anatomical Therapeutic Chemical Classification System codes and PBS item codes. Prevalence estimates were compared with a 4:1 matched non-depressed Australian representative population sample (10PCT) with PBS claims data available from 01/07/2010-31/12/2014. AGDS participants had a higher mean number of inferred comorbidities (4.6 ± 2.9) than individuals in the 10PCT sample (2.0 ± 2.1). Excluding depression, 89.1% of AGDS participants had at least one inferred comorbidity, most commonly pain (51.0%), inflammation/pain (40.3%), and anxiety (32.3%). Metabolic and cardiovascular conditions frequently co-occurred (13.2%). Within AGDS, comorbidity burden was higher among women and increased with age, body mass index, number of depressive episodes and symptoms, and annual healthcare costs. Median annual healthcare costs were approximately 65% higher among AGDS participants with 2-3 inferred comorbidities compared with those with none. This study provides a detailed description of treated comorbidities and associated healthcare costs among Australians living with depression. The findings highlight the substantial multimorbidity burden in this cohort and its association with increased healthcare costs to both the individual and health system.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"414 ","pages":"122397"},"PeriodicalIF":5.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal microstructural alterations as early phenotypes of depression in radiogenomics analysis.","authors":"Shilei Wang, Shuling Ye, Ming Feng, Zhifeng Zhou, Yuting Yang, Qinqin Zhang, KuangChing Lin, Sisi Chen, Fan Lu, Meixiao Shen, Zi Jin","doi":"10.1016/j.jad.2026.122413","DOIUrl":"10.1016/j.jad.2026.122413","url":null,"abstract":"<p><strong>Background: </strong>With the increasing prevalence of depression, there is an urgent clinical need for early screening in depression. The retina offers a promising window for early screening in depression due to its rapid, non-invasive, objective, eye-brain correlated characteristics, but previous research has yielded conflicting alterations in retinal microstructure in depression.</p><p><strong>Methods: </strong>We screened retinal optical coherence tomography and brain magnetic resonance imaging data in the UK Biobank to enroll 23,225 participants for retinal study of depression occurrence, and 1475 participants for the eye-brain association study. We also used genetic data (ID: ebi-a-GCST90014267 and ukb-d-20,448) from the Integrative Epidemiology Unit Open Genome-Wide Association Study for Mendelian randomization analysis. We used Cox regression to assess the association between retinal microstructure and depression risk, Mendelian randomization to infer causality, and mediation analysis to explore retina-brain pathway association.</p><p><strong>Results: </strong>The Cox regression analysis showed that retinal ganglion cell-inner plexiform layer (GCIPL) thickness remained a significant predictor of depression. The Mendelian randomization analysis indicated a positive statistical association between GCIPL thickness and depression. Moreover, there was a significant positive correlation (all p < 0.001) between the volume of specific depression-related brain regions and the GCIPL thickness. Adjusting for age, sex, and head size, the mediation analysis provided preliminary evidence for a potential anatomical pathway linking retinal GCIPL thickness to depression-related brain regions through primary visual cortex and secondary visual cortex volumes.</p><p><strong>Conclusion: </strong>Thickened retinal GCIPL is a potential early phenotype of depression and has a potential association pathway with depression-related brain regions using a radiogenomics approach.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"122413"},"PeriodicalIF":5.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-substrate-based full-color fluorescent probe TPE-4PA@Tb/Eu-GMP-acac ICPs for alkaline phosphatase detection and its on-site application for algal bloom alert.","authors":"Yuanyue Wu, Chunqian Yu, Yiwen Min, Changshun Chen, Ke Zhou, Wanying Zhai, Tianshu Zhou, Jingjing Deng","doi":"10.1016/j.talanta.2026.130159","DOIUrl":"10.1016/j.talanta.2026.130159","url":null,"abstract":"<p><p>The development of rapid, on-site analytical methods and test strips for alkaline phosphatase activity (APA) is crucial for addressing drinking water safety crises, as it enables eutrophication assessment and algal bloom warnings under phosphorus-limited conditions. In this study, we incorporate aggregation-induced emission luminogen (AIEgen) guest TPE-4PA into bimetallic lanthanide-based infinite coordination polymers (Tb/Eu-GMP ICPs). TPE-4PA exhibits unprecedented binding preference for Tb³⁺ over Eu³⁺, triggering coordination-induced emission (CIE) at 450 nm and modulating the antenna effect (AE) and the tandem energy transfer (TER) from Tb³⁺ to Eu³⁺. Subsequently, acetylacetone (acac) was further introduced to yield TPE-4PA@Tb/Eu-GMP-acac ICPs with an appropriate full-color fluoresce response capability. The addition of alkaline phosphatase (ALP) hydrolyzes GMP and TPE-4PA dual substrates, resulting in reduced characteristic emission of the bimetallic Ln-ICP host at 493, 548, 593, 619 and 703 nm, increased monomer emission of TPE-4PA at 392 nm, as well as the solvent-driven AIE of the enzymatic product TPE-4OH at 430 nm, which constitutes a novel ratiometric ALP sensing mechanism with pale-purple to blue fluorescence color shifts. Featuring high sensitivity, doubly assured selectivity, and operational simplicity, this \"all-in-one\" probe enables real-time APA monitoring via dual-substrate kinetics and is suitable for on-site ALP test strip development. Moreover, the unique color transition point of the dual-substrate-based TPE-4PA@Tb/Eu-GMP-acac ICPs probe can be designed to signal an APA surge prior to algal bloom onset, which holds significant potential for the development of microalgae pollution early-warning systems, thereby safeguarding drinking water safety.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"310 ","pages":"130159"},"PeriodicalIF":6.7,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148300521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ferrous iron-induced secondary mineral formation regulates organic carbon bioavailability and methane recovery from iron-enhanced primary sludge.","authors":"Feifei Chu, Fangmei Cheng, Xiaomeng Zhang, Liyan Wei, Xinhou Zhang, Yun Chen, Lei Zhao, Fei Yang, Nan Shen","doi":"10.1016/j.biortech.2026.135638","DOIUrl":"10.1016/j.biortech.2026.135638","url":null,"abstract":"<p><p>Iron salt-based chemically enhanced primary treatment effectively captures organic carbon from municipal wastewater, providing a concentrated substrate for methane recovery through anaerobic digestion. However, methane production from iron salt-based chemically enhanced primary sedimentation (Fe-CEPS) sludge remains substantially lower than expected, and the mechanisms responsible for this reduction remain poorly understood. Here, the relationship between iron-bound organic carbon (Fe-OC) formation and methane production was investigated by combining anaerobic digestion experiments with iron mineral-glucose model systems. Increasing Fe dosage reduced methane yield from 221.1 to 74.7 mL CH₄ g^-1 VS while promoting Fe-OC accumulation. A strong negative correlation was observed between Fe-OC content and methane production. Fresh Fe-CEPS sludge contained only limited Fe-OC (<10% of total organic carbon), whereas Fe-OC accounted for approximately 26% of total organic carbon after anaerobic digestion, indicating that Fe-OC formed predominantly during digestion rather than during coagulation. Iron speciation analyses revealed extensive Fe(III) reduction accompanied by secondary iron mineral formation. Model experiments further demonstrated that Fe(II)-induced mineral transformation increased mineral crystallinity, enhanced organic carbon stabilization, reduced carbon bioavailability, and consequently suppressed methane production. Scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy further revealed progressively stronger spatial associations between organic carbon and iron minerals as mineral crystallinity increased. These findings reveal a previously unrecognized mechanism whereby Fe(II)-induced secondary iron mineral formation promotes Fe-OC accumulation and reduces organic carbon bioavailability during anaerobic digestion. Regulating iron mineral transformation may therefore represent an effective strategy for improving methane recovery from iron-enhanced primary sludge.</p>","PeriodicalId":258,"journal":{"name":"Bioresource Technology","volume":" ","pages":"135638"},"PeriodicalIF":8.2,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148757002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LexA deficiency confers enhanced thermotolerance and glycogen accumulation in Methylomicrobium buryatense.","authors":"Shuqi Guo, Yamin Jing, Xiaohan Huang, Binghui Liu, Maximilian Lackner, Qiang Fei","doi":"10.1016/j.biortech.2026.135635","DOIUrl":"10.1016/j.biortech.2026.135635","url":null,"abstract":"<p><p>Systematic mining of heat stress factors is pivotal for constructing robust microbial cell factories. However, the genetic basis underlying thermotolerance remains poorly understood in C1 gas-utilizing chassis. Here, we identified LexA as a key regulator governing thermotolerance and glycogen accumulation in the methanotroph Methylotuvimicrobium buryatense 5GB1C. Through ultraviolet mutagenesis coupled with adaptive laboratory evolution, we developed a thermotolerant evolved strain 5C27. Whole-genome resequencing and transcriptomic analysis revealed global transcriptional reprogramming underlying the heat tolerance phenotype. Notably, LexA was sharply downregulated at 40 °C and identified as a core regulatory factor for thermoadaptation. Transcriptomic analysis indicated that the acquired thermotolerance arises from coordinated regulation of oxidative stress response, energy metabolism, and cellular homeostasis. Subsequent validation experiments demonstrated that lexA deficiency simultaneously conferred enhanced thermotolerance and redirected intracellular carbon flux, resulting in increased glycogen production that exceeded wild-type levels even at the optimal growth temperature of 30 °C. Collectively, our work demonstrated for the first time that LexA plays a critical regulatory role in thermotolerance of methanotrophs. This discovery also provides a foundation for advancing the development of thermotolerant cell factories and promotes the deployment of C1-gas industrial biomanufacturing.</p>","PeriodicalId":258,"journal":{"name":"Bioresource Technology","volume":" ","pages":"135635"},"PeriodicalIF":8.2,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148757702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute co-exposure to urban particulate matter and aircraft noise elicits lung-centered immune-redox proteomic remodeling in mice.","authors":"Corrado Ameli, Bharath Anila Bhuvanendran Nair, Amalie Schufri Klinkby, Marin Kuntic, Matthias Oelze, Ivana Kuntic, Elle Wilson, Omar Hahad, Alex von Kriegsheim, Thomas Münzel, Reka Toth, Andreas Daiber, Petr V Nazarov, Adelina Rogowska-Wrzesinska","doi":"10.1016/j.envpol.2026.129165","DOIUrl":"10.1016/j.envpol.2026.129165","url":null,"abstract":"<p><p>Particulate air pollution and transportation noise frequently co-occur, but their combined molecular effects are poorly defined. We used data-independent acquisition (DIA) LC-MS/MS proteomics to profile lung, brain, and heart from male C57BL/6J mice exposed for 3 days to NIST SRM 1648a urban particulate matter (PM), aircraft noise (NOISE), PM + NOISE, or control conditions. The exposure model is the acute co-exposure paradigm previously characterized with orthogonal functional, redox, and inflammatory endpoints by Kuntic et al. The lung was the dominant responsive organ. PM + NOISE produced the broadest pulmonary response and the strongest induction of immune and macrophage-associated proteins, including acute-phase, particle-handling, interferon-linked, and phagosome-associated markers. This immune signal was accompanied by NADPH oxidase and iron-handling components, altered epithelial barrier markers, and endothelial and extracellular-matrix perturbation. The principal pulmonary modules agreed with orthogonal endpoints previously measured in the parent exposure experiment, including pulmonary NOX-2 and HO-1 protein, in situ reactive oxygen species formation, Cd68 and Mcp-1 transcripts, circulating cytokines, increased systolic blood pressure, impaired endothelium-dependent relaxation of the aorta, and cerebral and retinal arteriolar microvascular dysfunction. Brain and heart responses were lower in amplitude and involved selective redox, neuronal, contractile, metabolic and matrix-associated programs. Observed-versus-expected analyses showed that most stress-responsive proteins scaled proportionally, whereas a smaller set enriched for ribosome, RNA-processing, and chromatin functions was constrained. Integration with transcriptomic data showed strong mRNA-protein concordance in lung and greater transcript-protein divergence in brain and heart. Acute co-exposure therefore increases early pulmonary immune-redox burden without uniform additive escalation across molecular systems.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":" ","pages":"129165"},"PeriodicalIF":7.2,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149035992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temperature shapes a modular division of labor among soil fungi to facilitate antibiotic dissipation.","authors":"Jiawen Yin, Yue Zhang, Wenhai Luo, Yanwen Ma, Ying Sun","doi":"10.1016/j.envpol.2026.129241","DOIUrl":"10.1016/j.envpol.2026.129241","url":null,"abstract":"<p><p>The antibiotics used in veterinary medicine accumulate in agricultural soils, where their persistence selects for antibiotic-resistance genes (ARGs). Soil fungi possess diverse metabolic enzyme systems and substantial potential for antibiotic biodegradation, but how temperature shapes fungal community succession and the functional pathways involved in antibiotic removal remains poorly understood. Herein, soils with histories of no fertilizer and organic fertilizer application (UF and OF, respectively) were spiked with 21 tetracyclines, quinolones and sulfonamides at approximately 2 mg kg^-1 per compound and incubated for 18 months at natural (NT; monthly mean of approximately 15 °C, ranging from -5.6 °C to 28.1 °C), constant (CT, 20 °C), and low (LT, 4 °C) temperatures. Dissipation kinetics were combined with fungal community and metagenomic profiling, co-occurrence networks, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway-residual correlations. Dissipation was slower in OF (total-antibiotic half-life [DT₅₀] of 22-58 d) than in UF (DT₅₀ of 18-44 d). Temperature exerted a stronger effect, with dissipation fastest at NT (DT₅₀ of 18-22 d) and slowest at LT (DT₅₀ of 44-58 d); ARGs followed the same trend, declining less than the parent compounds and least of all at LT. Temperature restructured the fungal community (PERMANOVA, P ≤ 0.018), chiefly by replacing taxa rather than by nested loss. Fungal-assigned KEGG pathways were inversely correlated with residual antibiotic concentrations (Spearman's ρ = -0.34 to -0.54, P < 0.05) and fell into three candidate functional modules: antibiotic capture and transport, oxidative transformation, and intracellular transformation. Across all temperatures the community retained a capture-and-transport core, for which no significant temperature contrast was detected, whereas oxidative and intracellular transformation were both less abundant at LT. Temperature therefore influences soil antibiotic dissipation by reshaping fungal community structure and redistributing annotated potential among complementary fungal functions. Accounting for this temperature dependence can improve bioremediation strategies for antibiotic-contaminated agricultural soils.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"410 ","pages":"129241"},"PeriodicalIF":7.2,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149056800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-entropy multimetallic nitrogen-doped carbon for robust ammonium-ion storage.","authors":"Hucheng Fu, Yiting Xu, Yizhang Yang, Yanchen Chen, Qiuyan Luo, Yiping Xu, Juguo Dai, Dongxu Li, Qiaoyun Qin, Andreu Cabot, Conghui Yuan, Guorong Chen, Lizong Dai","doi":"10.1016/j.jcis.2026.141010","DOIUrl":"10.1016/j.jcis.2026.141010","url":null,"abstract":"<p><p>Ammonium ions (NH₄⁺), owing to their abundance, low cost, and environmental friendliness, have emerged as promising non-metallic charge carriers for next-generation aqueous energy storage systems. However, the lack of suitable electrode materials has so far hindered their practical application. In this study, we report the development of a high-entropy multimetallic electrode material comprising uniformly dispersed Mn, Fe, Co, Ni, and Cu species on a conductive graphitized nitrogen-doped carbon framework. This engineered electrode enables high-performance symmetric NH₄⁺-ion supercapacitors. The multi-metal doping strategy significantly increases the density of electroactive sites, reduces NH₄⁺ diffusion barriers, and enhances structural stability. The optimized electrodes deliver a high specific capacitance of 836 F g^-1 at 1 A g^-1 and demonstrate excellent cycling performance, retaining 97.2% of their initial capacity and nearly 100% Coulombic efficiency after 50,000 cycles in a three-electrode system. Moreover, the assembled symmetric devices achieve energy densities exceeding 53 Wh kg^-1 at a power density of 891 W kg^-1. Density functional theory calculations confirm that the synergistic interaction among multiple metal centers optimizes NH₄⁺ adsorption and charge distribution, accounting for the superior electrochemical performance.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"723 ","pages":"141010"},"PeriodicalIF":9.6,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148325341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}