Chemical Methodologies最新文献_第3页

Green Synthesis of ZnO Nanoparticles via Sol-gel Method and Investigation of Its Application in Solvent-free Synthesis of 12-Aryl-tetrahydrobenzo[α]xanthene-11-one Derivatives Under Microwave Irradiation 溶胶-凝胶法绿色合成纳米ZnO及其在微波辐射下无溶剂合成12-芳基四氢苯并[α]杂蒽-11- 1衍生物中的应用研究

IF 5.6

Chemical Methodologies Pub Date : 2019-08-20 DOI: 10.33945/SAMI/CHEMM.2019.6.2

Saeid Taghavi Fardood, A. Ramazani, Farzaneh Moradnia, Z. Afshari, Sara Ganjkhanlu, F. Zare

引用次数: 28

Dithiocarbamate Modified SPION-Chitosan Nanobiocomposite, a Promising Adsorbent for Bovine Serum Albumin (BSA) 二硫代氨基甲酸酯修饰spion -壳聚糖纳米生物复合材料对牛血清白蛋白的吸附剂研究

IF 5.6

Chemical Methodologies Pub Date : 2019-07-15 DOI: 10.33945/SAMI/CHEMM.2019.5.5

Esmail Doustkhah, M. Heydarizadeh, Z. Fathi, H. Mohtasham, S. Rostamnia, Morteza Hasani

引用次数: 4

Studies on Isora Fibers Mixed with 1% Ricinoleic Acid Reinforced with Polypropylene 聚丙烯增强1%蓖麻油酸混纺Isora纤维的研究

IF 5.6

Chemical Methodologies Pub Date : 2019-06-03 DOI: 10.33945/SAMI/CHEMM.2019.6.9

A. U. Santhoskumar, N. Chitra

引用次数: 0

Metal-Organic Framework MIL-53(Fe) as a highly efficient reusable catalyst for the synthesis of 2-aryl-1H-benzimidazole 金属-有机骨架MIL-53(Fe)作为2-芳基- 1h -苯并咪唑合成的高效可重复使用催化剂

IF 5.6

Chemical Methodologies Pub Date : 2019-05-29 DOI: 10.33945/SAMI/CHEMM.2019.6.8

Azadeh Nozarie

引用次数: 9

Green Synthesis of Benzimidazole Derivatives: an Overview on Green Chemistry and Its Applications 苯并咪唑衍生物的绿色合成:绿色化学及其应用综述

IF 5.6

Chemical Methodologies Pub Date : 2019-03-26 DOI: 10.33945/SAMI/CHEMM.2019.6.1

M. Asif

{"title":"Green Synthesis of Benzimidazole Derivatives: an Overview on Green Chemistry and Its Applications","authors":"M. Asif","doi":"10.33945/SAMI/CHEMM.2019.6.1","DOIUrl":"https://doi.org/10.33945/SAMI/CHEMM.2019.6.1","url":null,"abstract":"The chemical substances in our environment are rising day by day. Only some of them are degraded, but most of them are non-degradable. These non-degradable substances produce pollutions which cause instability, harm or discomfort to the ecosystem as pollutions and create a risk to the environment. To reduce the possibility of a system we must reduce the risk not by altering the effect but by the cause. Thus, green chemistry (GC) concept was introduced, and it is a rapidly emerging field of chemistry. The GC is the design of chemical products and procedures that decrease or remove the use and production of harmful substances. In recent years, various heterocyclic compounds have appeared owing to the extensive varieties of their pharmacological activities. Benzimidazole is a heterocyclic aromatic compound. It is a vital and advantaged structure in medicinal chemistry and plays a role with ample therapeutic activities like analgesic, anti-inflammatory, antiulcer, antihypertensive, antibacterial, antiviral, antifungal, anticancer and antihistaminic. Because of its value, the processes for their synthesis have become a focus of synthetic chemists. Therefore, this review aims at compiling the chemistry of differently substituted benzimidazoles and some other methods. Conventional methods of synthesis need longer heating time, complicated and tedious apparatus set up which result in high cost and pollution in contrast to greener methods which are inexpensive.","PeriodicalId":9896,"journal":{"name":"Chemical Methodologies","volume":"56 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2019-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84504383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Improving degradation of polyethylene /acrylic dextrose with ground nut powder 用坚果粉改善聚乙烯/丙烯酸葡萄糖的降解

IF 5.6

Chemical Methodologies Pub Date : 2019-03-02 DOI: 10.22034/AJGC.2019.159847.1119

S. Umapathi, Jaya Chitra Natarajan

引用次数: 0

In Silico Study of Metoclopramide as A Small Molecule of Dopamine D2 Receptor: a Quantum-Mechanical (QM) Based Molecular Docking Treatment 甲氧氯普胺作为多巴胺D2受体小分子的计算机研究:量子力学(QM)分子对接处理

IF 5.6

Chemical Methodologies Pub Date : 2019-01-29 DOI: 10.22034/AJGC.2019.152832.1111

M. Nabati, Hossein Mohammadnejad-Mehrabani, Abdolnaser Tavakkoli, M. Mazidi, E. Lohrasbi, Afshar Gravand, Hamideh Sabahnoo

{"title":"In Silico Study of Metoclopramide as A Small Molecule of Dopamine D2 Receptor: a Quantum-Mechanical (QM) Based Molecular Docking Treatment","authors":"M. Nabati, Hossein Mohammadnejad-Mehrabani, Abdolnaser Tavakkoli, M. Mazidi, E. Lohrasbi, Afshar Gravand, Hamideh Sabahnoo","doi":"10.22034/AJGC.2019.152832.1111","DOIUrl":"https://doi.org/10.22034/AJGC.2019.152832.1111","url":null,"abstract":"The present research exploration will contain studying the molecular structure, bonds nature, stability, reactivity and electronic properties of the title molecule.The molecular optimization and all theoretical computations were carried out by density functional theory (DFT) method using the hybrid B3LYP (Becke, three-parameter, Lee-Yang-Parr) exchange-correlation functional employing the 6-31G(d,p) basis set of theory. Quantum-mechanical (QM) computations of the molecular structure geometry of the molecule under study were calculated with scaled quantum mechanics. The global reactivity descriptors like energy gap (Eg), ionization potential (IP), electron affinity (EA), chemical hardness (η), chemical softness (S), electronegativity (χ), electronic chemical potential (µ) and electrophilicity index (ω) can be obtained from the energies of the frontier molecular orbitals (HOMO and LUMO). The calculated global reactivity indices indicated that metoclopramide which was a stable small molecule can bind with the residues of the dopamine D2 receptor (D2R). Molecular docking studies showed that the steric interactions of the ligand with the residues Phe 198, Phe 382, Ala 122, Thr 119, Ser 197, Trp 386, Phe 390, Val 115, Cys 118 and Asp 114 from the protein binding site are the main binding modes between the ligand and the receptor.","PeriodicalId":9896,"journal":{"name":"Chemical Methodologies","volume":"32 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87021008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6