Chemical Methodologies最新文献

Simultaneous Determination of Ramipril and Amlodipine Besylate in Tablet Dosage form by First Order Derivative Spectrophotometric Method 一阶导数分光光度法同时测定片剂中雷米普利和苯磺酸氨氯地平的含量

IF 5.6

Chemical Methodologies Pub Date : 2020-06-01 DOI: 10.33945/sami/chemm.2020.4.8

A. Patel, H. M. Jadav, A. Vyas, Ajay I. Patel, Nilesh Patel, A. Chudasama

{"title":"Simultaneous Determination of Ramipril and Amlodipine Besylate in Tablet Dosage form by First Order Derivative Spectrophotometric Method","authors":"A. Patel, H. M. Jadav, A. Vyas, Ajay I. Patel, Nilesh Patel, A. Chudasama","doi":"10.33945/sami/chemm.2020.4.8","DOIUrl":"https://doi.org/10.33945/sami/chemm.2020.4.8","url":null,"abstract":"The aim of present study was to develop a simple, precise, accurate and reproducible spectrophotometric method for simultaneous determination of ramipril and amlodipine besylate by UV-visible spectrophotometer using the first order derivative method. According to our present knowledge, no first order derivative method was reported so far. Thus, in present study it was decided to carry out first order derivative method and it was validated in compliance with ICH (Q2 R1) guideline. Ramipril and amlodipine besylate showed absorbance at the working wavelength of 211.87 nm (zero crossing point of amlodipine besylate) and 254.34 nm (zero crossing point of ramipril) respectively using distilled water as a diluent. Linearity was established over the concentration range of 2-25 μg/mL and 2-50 μg/mL for ramipril and amlodipine besylate with correlation coefficient 0.999 and 0.998 respectively. Accuracy was obtained between 99.91-101.06% and 99.66-100.66% for ramipril and amlodipine besylate respectively. LOD were found to be 0.078 μg/mL and 0.059 μg/mL and LOQ were 0.239 μg/mL and 0.178 μg/mL for ramipril and amlodipine besylate respectively. The results revealed that the developed method is suitable for the routine analysis of determining of ramipril and amlodipine besylate in a tablet dosage form.","PeriodicalId":9896,"journal":{"name":"Chemical Methodologies","volume":"14 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75663509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Preparation of Xanthan Magnetic Biocompatible Nano-Composite for Removal of Ni^2+ from Aqueous Solution 黄原胶磁性生物相容性纳米复合材料去除水中Ni^2+的制备

IF 5.6

Chemical Methodologies Pub Date : 2020-06-01 DOI: 10.33945/sami/chemm.2020.4.9

A. Bozorgian, S. Zarinabadi, A. Samimi

{"title":"Preparation of Xanthan Magnetic Biocompatible Nano-Composite for Removal of Ni^2+ from Aqueous Solution","authors":"A. Bozorgian, S. Zarinabadi, A. Samimi","doi":"10.33945/sami/chemm.2020.4.9","DOIUrl":"https://doi.org/10.33945/sami/chemm.2020.4.9","url":null,"abstract":"This study investigates the uptake of the nickel (II) metal ions from aqueous sources using the xanthan magnetic biocompatible nano-composites. The desired nano-sorbent was first synthesized, analysed, and evaluated by scanning electron microscope (SEM) and Fourier transform infrared spectroscopy and (FT-IR), then used as adsorbent for removing the nickel from aqueous solution. Then the effect of different parameters such as contact time, adsorbent amount, pH, initial concentration, and temperature on the adsorption rate was investigated. The equilibrium time for the stirring state was 60 min and the optimum adsorbent value was 0.1 g and the acidity of 4 was the best pH. The highest removal efficiency was obtained at 97.6%. The kinetic studies of nickel removal by the synthesized adsorbent were performed and the results obtained for batch experiments follow the pseudo-quadratic kinetic model with (R2=0.9987). Equilibrium adsorption studies also revealed that, the adsorption process was in better agreement with the Freundlich isotherm (R2=0.9978). The positive Gibbs free energy (15.08 KJ/mole-1) showed that the process was spontaneous. Also the entropy changes was positive (0.03 KJ/mole-1), indicated an increase in entropy during the adsorption process in the system. Therefore, the adsorption process was associated with increasing the disorder.","PeriodicalId":9896,"journal":{"name":"Chemical Methodologies","volume":"15 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89259820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Isolation and Characterization of Fatty Acid Derivatives from the Stem Barks of Albizia Amara (Fabaceae), Sudanese Medicinal Plant 苏丹药用植物紫花苜蓿茎皮脂肪酸衍生物的分离与鉴定

IF 5.6

Chemical Methodologies Pub Date : 2020-06-01 DOI: 10.33945/sami/chemm.2020.4.1

I. Abdurrahman, Yang Cai-Xiab

引用次数: 8

Theoretical Study of the Reaction Among Isocyanide, Dialkyl Acetylenedicarboxylate and Acetic Anhydride: The Investigation of the Reaction 异氰酸酯、二烷基乙炔二羧酸酯和乙酸酐反应的理论研究:反应的研究

IF 5.6

Chemical Methodologies Pub Date : 2020-06-01 DOI: 10.33945/sami/chemm.2020.4.11

Batoul Maki̇abadi̇, M. Zakari̇anezhad, Fahimeh Koorkinejad, H. Mehdizadeh

{"title":"Theoretical Study of the Reaction Among Isocyanide, Dialkyl Acetylenedicarboxylate and Acetic Anhydride: The Investigation of the Reaction","authors":"Batoul Maki̇abadi̇, M. Zakari̇anezhad, Fahimeh Koorkinejad, H. Mehdizadeh","doi":"10.33945/sami/chemm.2020.4.11","DOIUrl":"https://doi.org/10.33945/sami/chemm.2020.4.11","url":null,"abstract":"In this work, stepwise reaction mechanism of the [2+3] cycloaddition reaction among alkyl isocyanides (contains tert-butyl isocyanide, cyclo hexyl isocyanide) with dialkyl acetylenedicarboxylate (contains dimethyl acetylenedicarboxylate, diethyl acetylenedicarboxylate and di-tert-butyl acetylenedicarboxylate) at the presence of acetic anhydride was investigated both in the gas phase and in solvent was studied theoretically. The potential energy of all structures participated in the reaction path was evaluated. The geometry of all the structures participated during the reaction path, the rate-determining step, and potential competitive routes during the reaction coordinate were evaluated. Also, dielectric constant effect of the solvent, the effect of substituted alkyl groups on the potential energy surfaces, and the best product configuration were investigated based upon the quantum mechanical calculations. For better understanding of the molecular interaction, the natural bond orbital method (NBO) and AIM analysis were applied. The results indicated that, the first step of the reaction was recognized as rate-determining step and the reaction rate was predicted to be dependent on the concentration of alkyl isocyanides and dialkyl acetylenedicarboxylate. It was also found that, the electron donating of different alkyl groups was not the main factor for the variation in the potential energy surfaces of the reaction; however, the steric factor of the bulky alkyl groups participating in the reaction path was found to be the main factor.","PeriodicalId":9896,"journal":{"name":"Chemical Methodologies","volume":"62 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75022000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Green Chemistry: Principles, Applications, and Disadvantages 绿色化学:原理、应用和缺点

IF 5.6

Chemical Methodologies Pub Date : 2020-06-01 DOI: 10.33945/SAMI/CHEMM.2020.4.4

Wanisa Abdussalam-Mohammed, A. Ali, Asma Omar Errayes

{"title":"Green Chemistry: Principles, Applications, and Disadvantages","authors":"Wanisa Abdussalam-Mohammed, A. Ali, Asma Omar Errayes","doi":"10.33945/SAMI/CHEMM.2020.4.4","DOIUrl":"https://doi.org/10.33945/SAMI/CHEMM.2020.4.4","url":null,"abstract":"This work provides an overview on applicability of 12 principles of green chemistry. Green chemistry is a term that indicates the creation of chemical products and procedures that reduces the use and production of harmful materials. The goals of green chemistry for protecting the environment can be achieved via several main directions. Some of them are bio-catalysis, use of alternative repeatable raw materials (biomass), alternative reaction solution (such as ionic liquids, supercritical fluids, water), alternative reaction circumstances (microwave activation) as well as to new photocatalytic reactions. Moreover, keep natural resources on earth without using harmful materials is the main objective of green chemistry. By changing patterns of consumption and production, steps are being taken to decrease the pollution and harmful waste, which considered being one of the important goals of green chemistry. Also, it was found that, it is so serious to develop alternative technologies that are safer for both human health and the environment to prevent any further damage to human health and the environment such as reducing release of dangerous chemicals to air leading to reduce damage to lungs. In addition, design safer chemical found to be a good opportunity to improve some chemical methods via producing cleaner and cheaper products in industrial processes when harmful chemicals are replacing with biological enzymes. For all the reasons outlined here, in this review, 12 principles of green chemistry are outlined with their applications, where shows how green chemistry reduces the impact of chemical processes on the environment and how their benefit can be achieved. And, also disadvantages of 12 principles are discussed, as well.","PeriodicalId":9896,"journal":{"name":"Chemical Methodologies","volume":"30 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78001193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 31

Synthesis and Characterization of Aluminium Sulphide (Al2S3) Thin Films 硫化铝(Al2S3)薄膜的合成与表征

IF 5.6

Chemical Methodologies Pub Date : 2019-11-01 DOI: 10.33945/sami/chemm.2019.6.4

I. Ikhioya, B. Ijabor, G. M. Whyte, F. Ezema

{"title":"Synthesis and Characterization of Aluminium Sulphide (Al2S3) Thin Films","authors":"I. Ikhioya, B. Ijabor, G. M. Whyte, F. Ezema","doi":"10.33945/sami/chemm.2019.6.4","DOIUrl":"https://doi.org/10.33945/sami/chemm.2019.6.4","url":null,"abstract":"The synthesis of Al2S3 thin film was carryout using electrodeposition technique. The electrodeposition bath system is composed of a source of cation (i.e. AlSO4.17H2O for Al2+) and a source of anion (i.e. Na2SO4 for S2-). Indium doped Tin Oxide (ITO) was used as the cathode while the anode was carbon and fluorine electrode. The temperature was varied by heating the entire precursor using a standard heating mantle with temperature ranges from 20 °C- 120 °C and the growth of Al2S3 thin films was carried out using the temperature range from 50 °C-80 °C at interval of 10 °C which later was converted to Kelvin. The XRD was found to be of wurtzite-like structure as hexagonal crystal structure that corresponds to 100, 110 and 111 plane. All the samples deposited at different temperature are crystalline in nature with lattice constant, (). Scanning electron microscopy (SEM) was carried out to reveal the micro-structural properties of aluminium sulphide thin films material. It was observed that as the wavelength of the incident radiation increases the absorbance of the material decreases. The sample deposited at 353 K recorded the highest absorbance at 380 nm. The sample deposited at 333 K recorded the highest transmittance at 1180 nm. Al2S3 film has a low transmittance less than 30% in the visible wavelength 520–720 nm and less than 60% transmittance in the near infrared wavelength 760–1200 nm which showed that as the wavelength of the incident radiation increases the transmittance of the films increases. The resistivity of the material decreases as the temperature and thickness of the materials increases while the conductivity of the material increases as the temperature and thickness of the material increases. The band gap energy of Al2S3 thin films deposited at (323 K-353 K) as obtained from the plot is given as 2.4-3.0 eV.","PeriodicalId":9896,"journal":{"name":"Chemical Methodologies","volume":"32 1","pages":""},"PeriodicalIF":5.6,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74895875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Vanadium(IV) Schiff base Complex: Synthesis, Characterization, Crystal Structure and Thermal Decomposition into V2O5 Particles 钒(IV)希夫碱配合物:合成、表征、晶体结构和热分解成V2O5颗粒

IF 5.6

Chemical Methodologies Pub Date : 2019-11-01 DOI: 10.33945/SAMI/CHEMM.2019.6.3

A. D. Khalaji, M. Ghorbani, S. J. Peyghoun, N. Feizi, A. Akbari, W. Hornfeck, M. Dušek, V. Eigner

引用次数: 1

Lithium–functionalization of Pyrrole–n–carboxylic Acids (n=1, 2, 3) 吡咯- n -羧酸(n= 1,2,3)的锂功能化

IF 5.6

Chemical Methodologies Pub Date : 2019-11-01 DOI: 10.33945/SAMI/CHEMM.2019.6.5

N. Ghasemi, M. Mirzaei

引用次数: 4

Theoretical Study of First Singlet Excited State of Para-Substituted Platinabenzene Complexes 对取代铂-苯配合物第一单重态激发态的理论研究

IF 5.6

Chemical Methodologies Pub Date : 2019-11-01 DOI: 10.33945/sami/chemm.2019.6.7

Gholamreza Ghane Shalmani, R. Ghiasi, A. Marjani

引用次数: 1

Evaluation of Ground and Excited State Dipole Moments of 2(3)-tetra(tert-butylphenoxy)phthalocyaninato Zinc(II) from Solvatochromic Data 从溶剂变色数据评价2(3)-四(叔丁基苯氧基)酞菁锌(II)的基态和激发态偶极矩

IF 5.6

Chemical Methodologies Pub Date : 2019-11-01 DOI: 10.33945/sami/chemm.2019.6.6

A. Ogunsipe, Patrick C. Bokolo

引用次数: 1