Esmail Doustkhah, M. Heydarizadeh, Z. Fathi, H. Mohtasham, S. Rostamnia, Morteza Hasani
{"title":"二硫代氨基甲酸酯修饰spion -壳聚糖纳米生物复合材料对牛血清白蛋白的吸附剂研究","authors":"Esmail Doustkhah, M. Heydarizadeh, Z. Fathi, H. Mohtasham, S. Rostamnia, Morteza Hasani","doi":"10.33945/SAMI/CHEMM.2019.5.5","DOIUrl":null,"url":null,"abstract":"In the present paper, bovine serum albumin (BSA) was studied for extraction case from a buffer solution through a new version of modified magnetic chitosan nanocomposite. Post-modification of this magnetic chitosan led to conversion of amine groups to dithiocarbamate on the surface of chitosan which was wrapped to superparamagnetic iron oxide nanoparticles (SPION). Chitosan was converted to magnetic chitosan over co-precipitation of Fe2+ and Fe3+ under alkali conditions. Amines of chitosan were also converted to dithiocarbamate over the reaction of carbon disulfide. Study of the synthesized support in BSA extraction was achieved in further experiments.","PeriodicalId":9896,"journal":{"name":"Chemical Methodologies","volume":null,"pages":null},"PeriodicalIF":3.5000,"publicationDate":"2019-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Dithiocarbamate Modified SPION-Chitosan Nanobiocomposite, a Promising Adsorbent for Bovine Serum Albumin (BSA)\",\"authors\":\"Esmail Doustkhah, M. Heydarizadeh, Z. Fathi, H. Mohtasham, S. Rostamnia, Morteza Hasani\",\"doi\":\"10.33945/SAMI/CHEMM.2019.5.5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the present paper, bovine serum albumin (BSA) was studied for extraction case from a buffer solution through a new version of modified magnetic chitosan nanocomposite. Post-modification of this magnetic chitosan led to conversion of amine groups to dithiocarbamate on the surface of chitosan which was wrapped to superparamagnetic iron oxide nanoparticles (SPION). Chitosan was converted to magnetic chitosan over co-precipitation of Fe2+ and Fe3+ under alkali conditions. Amines of chitosan were also converted to dithiocarbamate over the reaction of carbon disulfide. Study of the synthesized support in BSA extraction was achieved in further experiments.\",\"PeriodicalId\":9896,\"journal\":{\"name\":\"Chemical Methodologies\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2019-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemical Methodologies\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33945/SAMI/CHEMM.2019.5.5\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Methodologies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33945/SAMI/CHEMM.2019.5.5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Dithiocarbamate Modified SPION-Chitosan Nanobiocomposite, a Promising Adsorbent for Bovine Serum Albumin (BSA)
In the present paper, bovine serum albumin (BSA) was studied for extraction case from a buffer solution through a new version of modified magnetic chitosan nanocomposite. Post-modification of this magnetic chitosan led to conversion of amine groups to dithiocarbamate on the surface of chitosan which was wrapped to superparamagnetic iron oxide nanoparticles (SPION). Chitosan was converted to magnetic chitosan over co-precipitation of Fe2+ and Fe3+ under alkali conditions. Amines of chitosan were also converted to dithiocarbamate over the reaction of carbon disulfide. Study of the synthesized support in BSA extraction was achieved in further experiments.