Central Plains Medical Journal最新文献

{"title":"Clinical analysis on 16 cases of cerebral rebleeding after stent-assisted embolization of ruptured intracranial aneurysm","authors":"Song Zhang, S. Guan","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.007","url":null,"abstract":"Objective \u0000To analyze the causes and prevention of cerebral rebleeding after stent-assisted embolization of ruptured intracranial aneurysm \u0000 \u0000 \u0000Methods \u0000A total of 655 patients who underwent single-stent-assisted spring coil embolization of an intracranial ruptured aneurysm from January 2011 to December 2017 in the First Affiliated Hospital of Zhengzhou University were selected. Of them, 16 patients with single aneurysms had perioperative surgery-related re-hemorrhage, 4 males and 12 females, aged 21 to 84 years. The re-hemorrhage and clinical outcomes of 16 patients were counted, and the modified Rankin (mRS) score was evaluated. \u0000 \u0000 \u0000Results \u0000The incidence of perioperative rebleeding in 655 patients was 2.4% (16/655). In the 16 cases, 9 cases had intraoper-ative aneurysm rebleeding, 5 cases died, 1 case had mRS score 4 points, and 3 cases mRS score 1 point. There were 7 cases of postoperative rebleeding, 5 cases of aneurysm rebleeding, 4 cases of death, 1 case of decompressive craniectomy after interventional therapy, and mRS score was 4 points at discharge. Two cases of brain parenchymal hemorrhage, 1 case of death, 1 case of cerebral infarction after discontinuation of dual antiplatelet aggregation drugs, mRS score was 2 points at discharge. \u0000 \u0000 \u0000Conclusions \u0000The causes of rebleeding after interventional treatment of ruptured aneurysm are complicated. For surgical rebleeding, the anti-platelet aggregation drugs application scheme can be adjusted according to the patients’situation, or interventional remedy, surgical combined treatment, effective technical level of operators can be used for effective prevention. \u0000 \u0000 \u0000Key words: \u0000Intracranial aneurysm; Subarachnoid hemorrhage; Stent-assisted embolization","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"5 1","pages":"23-25"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76317017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of rebamipide tablets combined with rabeprazole sodium enteric-coated tablets in the treatment of chronic atrophic gastritis","authors":"Y. Xue, Jing Li, Yunfeng Hou","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.031","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.031","url":null,"abstract":"Objective \u0000To analyze the efficacy and safety of rebamipide tablets combined with rabeprazole sodium enteric-coated tablets in the treatment of chronic atrophic gastritis (CAG). \u0000 \u0000 \u0000Methods \u0000A total of 192 CAG patients admitted to Central Hospital of Henan Energy Jiaozuo Coal Industry Group from January 2013 to January 2018 were included and randomly divided into control group and observation group according to the ratio of 1∶1, with 96 cases in each group. Control group was treated with rabeprazole sodium enteric-coated tablets, and observation group was given rebamipide tablets + rabeprazole sodium enteric-coated tablets, and they were treated for 4 weeks. The clinical efficacy, pathological scores (gland atrophy, intestinal metaplasia, dysplasia), gastric function-related indicators, including gastrin-17 (GAS-17), pepsinogen I (PGI), epidermal growth factor (EGF), endothelin-1 (ET-1), Hp eradication rate and safety were compared between the two groups. \u0000 \u0000 \u0000Results \u0000After treatment, the total improvement rate of treatment and negative conversion rate of Hp in observation group were significantly higher than those in control group, (91.67% and 80.21%) vs. (78.12% and 62.50%), the difference was statistically significant (P 0.05), with good safety. \u0000 \u0000 \u0000Conclusions \u0000Rebamipide tablets combined with rabeprazole sodium enteric-coated tablets has obvious effects on CAG, and it can effectively alleviate the clinical symptoms of patients and regulate the levels of gastric function-related indicators, with good safety. \u0000 \u0000 \u0000Key words: \u0000Rebamipide tablets; Rabeprazole sodium enteric-coated tablets; Chronic atrophic gastritis","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"8 1","pages":"100-103"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84149606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant congenital melanocytic nevus and malignant transforation: a case report and literature review","authors":"Jingjing Tang, Xiao-ming Zhao, G. Sheng","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.037","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.037","url":null,"abstract":"Objective \u0000To investigate the diagnosis and differential diagnosis of malignant transformation in children with giant congenital melanocyte nevus (GCMN). \u0000 \u0000 \u0000Methods \u0000The clinical features and results of various auxiliary examinations (including imaging and laboratory) from one GCMN child treated in the First Affiliated Hospital of Zhengzhou University in July 2017 were retrospectively analyzed. And related literature was reviewed. \u0000 \u0000 \u0000Results \u0000Results of imaging, pathology, bone marrow cytology, immunohistochemistry, flow cytology and other examinations and clinical symptoms were synthetically considered. As a result, this case was diagnosed with malignant GCMN with hepatic and bone-marrow metastases. \u0000 \u0000 \u0000Conclusions \u0000The diagnosis of bone marrow metastasis of malignant melanoma mainly depends on the morphological examination of bone marrow biopsy smear. The definite diagnosis of bone marrow metastasis of malignant melanoma depends on the comprehensive analysis of clinical symptoms, pathological diagnosis, cell morphology and cytochemical staining. \u0000 \u0000 \u0000Key words: \u0000Giant congenital melanocytic nevus; Bone marrow cytology; Pathology","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"1 1","pages":"122-124"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90498171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Levels and clinical significance of homocysteine in serum and D-dimer in plasma of patients with non-small cell lung cancer","authors":"Yu-jiao Feng, Yan Kang, Caili Pei, Xue-ying Tian","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.010","url":null,"abstract":"Objective \u0000To investigate the levels and clinical significance of homocysteine in serum and D-dimer in plasma of patients with non-small cell lung cancer . \u0000 \u0000 \u0000Methods \u0000A total of 126 patients with non-small cell lung cancer who were admitted to Shanxi Provincial Cancer Hospital from June 2016 to July 2019 were selected as the study group, another 126 healthy people who came to hospital for physical examination during the same period were selected as the control group. The serum homocysteine and plasma D-dimer were detected in both groups, and the results were compared between the two groups and within the study group (before and after treatment). \u0000 \u0000 \u0000Results \u0000The serum homocysteine and plasma D-dimer levels in study group were higher than those in control group (P<0.05). In study group, the serum homocysteine and plasma D-dimer levels after treatment were lower than those before treatment (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Serum homocysteine and plasma D-dimer levels can be used as the main reference in the diagnosis of non-small cell lung cancer. \u0000 \u0000 \u0000Key words: \u0000Non-small cell lung cancer; Homocysteine; D-dimer","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"123 1","pages":"32-34"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90870390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application and early clinical efficacy of three-dimensional printed nail guide in atlantoaxial internal fixation","authors":"chaojun Xu, Yingjie Hao, Lei Yu, Guangduo Zhu, Z. Ren, Cheng Peng, Panke Zhang, Jian Zhu","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.005","url":null,"abstract":"Objective \u0000To investigate the application and early clinical efficacy of three-dimensional printed nail guide in atlantoaxial internal fixation. \u0000 \u0000 \u0000Methods \u0000A total of 48 patients with axillary internal fixation assisted by three-dimensional printed nail guides from May 2016 to July 2018 in the First Affiliated Hospital of Zhengzhou University were selected, including 30 cases of atlantoaxial dislocation, 17 cases of atlantoaxial dislocation with odontoid fracture, 1 case of reconstruction of the left vertebral artery rupture in a conventional posterior atlantoaxial internal fixation. The postoperative follow-up period was 15 to 40 months, and the effect was analyzed. \u0000 \u0000 \u0000Results \u0000A total of 192 screws were placed in 48 patients, of them 190 cases in grade 0 (C1 94 screws in C2 96 screws), accounting for 98.96%, 2 cases in grade I (C1), accounting for 1.04%, and 0 case in grade Ⅱ. The acceptance rate was 100%, no nerve or vertebral artery injury occured during operation. The 17 patients with odontoid fractures all healed after operation, and the efficacy evaluation indicators at the last follow-up were improved compared with those before surgery (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The three-dimensional printing navigation template for atlantoaxial internal fixation can assist in the placement of nails, and the placement of nails is more accurate, and the nerve and blood vessel damage during surgery is reduced. \u0000 \u0000 \u0000Key words: \u0000Three-dimensional printing; Navigation template; Atlantoaxial; Internal fixation","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"10 1","pages":"16-19"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76476610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors of cerebral infarction in elderly patients undergoing hip replacement","authors":"Peiqiang Li, Jiajia Li, Hong-xing Ma","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.017","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.017","url":null,"abstract":"Objective \u0000To investigate the risk factors associated with cerebral infarction in elderly patients undergoing hip replacement. \u0000 \u0000 \u0000Methods \u0000A total of 247 elderly patients who underwent hip replacement in Luoyang Central Hospital Affiliated to Zhengzhou University from March 2016 to March 2019 were selected, including 20 patients with cerebral infarction (infarction group) and 227 patients without cerebral infarction (non infarction group). The clinical data of the two groups were compared, and the risk factors of cerebral infarction were analyzed by logistic analysis. \u0000 \u0000 \u0000Results \u0000The general data of the two groups showed significant differences in age, body mass index (BMI), history of cerebral infarction, history of diabetes, history of hypertension and disease type (P 0.05). The perioperative anticoagulation, anesthesia methods, intraoperative hypotension, and American Society of Nesthesiologists (ASA) grades had significant difference between groups (P 69 years), history of cerebral infarction, diabetes, BMI (>24 kg/m2), history of hypertension, intraoperative hypotension, ASA grade (≥3), general anesthesia were independent risk factors associated with cerebral infarction (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Age (>69 years), history of cerebral infarction, diabetes, BMI (>24 kg/m2), history of hypertension, intraoperative hypotension, ASA grade (≥3), general anesthesia are independent risk factors associated with cerebral infarction in elderly patients undergoing hip replacement. \u0000 \u0000 \u0000Key words: \u0000Aged; Hip replacement; Perioperative period; Cerebral infarction","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"80 1","pages":"55-58"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75955178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of ultrasound interventional biopsy in diagnosis of phyllode tumors of breast","authors":"Xiaona Liu","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.018","url":null,"abstract":"Objective \u0000To investigate the diagnostic value of interventional ultrasound biopsy for phyllode tumor of breast (PTB). \u0000 \u0000 \u0000Methods \u0000Forty-eight female patients with PTB diagnosed by surgical pathological examination from April 2016 to June 2018 in Datong Coal Mine General Hospital were selected. Forty-eight patients were 30 to 65 years old, 36 cases were benign PTB, 7 cases were borderline, and 5 cases were malignant. The ultrasound imaging manifestations of patients were analyzed, and the accuracy between the results of ultrasound interventional biopsy and surgical pathological diagnosis were calculated. \u0000 \u0000 \u0000Results \u0000The accuracy of ultrasound interventional biopsy in the diagnosis of PTB was 95.83% (46/48), and the proportions of benign, borderline, and malignant diagnostis of PTB were 34/36 (94.44%), 7/7, and 5/5. The ultrasound images of 34 patients with benign PTB and 9 patients with bordering PTB showed lobulated tumors, major diameter <5.0 cm, solid internal echo, clear edges, no or small blood flow signals, and 5 patients with PTB malignant tumors were round or oval, with a length of ≥5.0 cm, the internal echos were cystic, the edges were blurred, and the blood flow signals were abundant. \u0000 \u0000 \u0000Conclusions \u0000Ultrasound interventional biopsy has high accuracy in the diagnosis of PTB, and can provide imaging information such as location, long diameter, and morphology of tumor, and can provide basis for subsequent surgical treatment. \u0000 \u0000 \u0000Key words: \u0000Phyllode tumor of breast; Ultrasound interventional biopsy; Pathological examination","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"18 1","pages":"58-60"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85269756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of clinical and imaging findings of Hirschsprung disease versus allied Hirschsprung disease","authors":"Changqing Lin","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.016","url":null,"abstract":"Objective \u0000To compare the clinical and imaging findings of children with Hirschsprung’s disease and allied Hirschsprung’s disease. \u0000 \u0000 \u0000Methods \u0000A total of 80 children with Hirschsprung’s disease and allied Hirschsprung’s disease who were admitted to the Department of Radiology of Shanxi Children’s Hospital from September 2014 to October 2019 were selected as the subjects of this study. According to the results of pathological examination, they were divided into group A (children with Hirschsprung’s disease, n=37) and group B (children with allied Hirschsprung’s disease, n=43). The clinical data of patients in group A and group B were analyzed retrospectively. Both groups received X-ray and barium enema before pathological examination. The clinical data, X-ray and barium enema results were compared and analyzed. \u0000 \u0000 \u0000Results \u0000There was no significant difference in sex, mean age, gestational age, delivery mode, clinical manifestation, anal examination between the two groups (P>0.05). In group A, the proportion of transitional segment (83.78%) was significantly higher than that in group B (6.98%), the proportion of irregular contraction in group A (37.84%) was significantly lower than that in group B (88.37%), the difference was statistically significant (P 0.05); the residual sites of barium between the two groups after 24 hours of barium enema were compared, the differences were not statistically significant (P>0.05); the diameter of colon between the two groups was compared, the difference was not statistically significant (P>0.05); the angle between the dilated segment and the transitional segment/spasm segment was larger in group A than that in group B (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The clinical data of children with Hirschsprung’s disease and allied Hirschsprung’s disease are similar, but there are significant differences between them by X-ray barium enema. \u0000 \u0000 \u0000Key words: \u0000Hirschsprung disease; Allied Hirschsprung disease; Clinical manifestation; Imaging findings","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"35 1","pages":"51-54"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85072414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of efficacy of oxaliplatin versus paclitaxel in combination with 5-fluorouracil chemotherapy in patients with gastric cancer after radical operation","authors":"Hongduo Jiao, Ruinuo Jia, Lingling Zhang, Bian-Ying Li","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.033","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.033","url":null,"abstract":"Objective \u0000To compare and analyze the chemotherapy value of oxaliplatin + 5-fluorouracil and paclitaxel + 5-fluorouracil after radical gastrectomy. \u0000 \u0000 \u0000Methods \u0000A total of 150 patients with gastric cancer who underwent radical gastrectomy in the First Affiliated Hospital of Henan University of Science and Technology from January 2014 to July 2016 were divided into study group (n=75) and control group (n=75). The patients in study group received oxaliplatin + 5-fluorouracil chemotherapy and the patients in control group received paclitaxel + 5-fluorouracil chemotherapy. The long-term effect, adverse reactions and quality of life of the two groups were recorded. \u0000 \u0000 \u0000Results \u0000The progression free survival time was compared between the two groups, the difference was not statistically significant (P>0.05); the recurrence rate, tumor free survival rate, metastasis rate and mortality were compared between the two groups, the differences were not statistically significant (P>0.05); chemotherapy drug-related myelosuppression (25.33%) and elevation of alanine aminotransferase (1.33%) in study group were lower than those in control group (49.33%, 9.33%), the differences were not statistically significant (P>0.05); adverse reactions of other chemotherapy drugs between the two groups were compared, the differences were not statistically significant (P>0.05); WHOQOL-100 scores were compared between the two groups before chemotherapy, the differences were not statistically significant (P>0.05); the score of WHOQOL-100 in the control group after chemotherapy was significantly lower than that before chemotherapy (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Chemotherapy with oxaliplatin + 5-fluorouracil and paclitaxel + 5-fluorouracil is effective after radical gastrectomy for gastric cancer, but the former is safe and beneficial to the quality of life of patients. \u0000 \u0000 \u0000Key words: \u0000Gastric cancer; Oxaliplatin; Paclitaxel; 5-fluorouracil; Radical operation","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"1 1","pages":"107-110"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73268232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution and drug resistance of Escherichia coli producing extended-spectrum β-lactamase","authors":"Ying Zhang, Wei Liu","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.013","url":null,"abstract":"Objective \u0000To investigate the clinical distribution and drug resistance of Escherichia coli producing extended-spectrum β-lactamase (ESBLs). \u0000 \u0000 \u0000Methods \u0000A total of 506 Escherichia coli strains were detected in Kaifeng Central Hospital from January 2016 to December 2017. The strains were isolated from 506 inpatients with non-digestive infections. The K-B disk diffusion method was used to detect drug resistance, and phenotypic confirmatory test was used to test the producing ESBLs strains. The strains distribution were recorded and their drug resistance conditions were analyzed. \u0000 \u0000 \u0000Results \u0000The 506 strains of Escherichia coli were more common in the respiratory tract (40.32%, 204/506), followed by the urinary tract (21.74%, 110/506), of which 116 strains (22.92%, 116/506) produced ESBLs. Both producing ESBLs strains and non-ESBLs strains did not show obvious resistance to imipenem, ertapenem, meropenem, and tigecycline. The drug resistance rate of producing ESBLs strains to other commonly used antibiotics was higher than that of non-ESBLs strains (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Escherichia coli is mainly related to lower respiratory tract and urinary system infections. ESBLs-producing strains are more resistant than non-ESBLs strains. \u0000 \u0000 \u0000Key words: \u0000Escherichia coli; Producing extended-spectrum β-lactamase; Respiratory tract infection","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"46 1","pages":"41-44"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87556705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}