Comparison of clinical and imaging findings of Hirschsprung disease versus allied Hirschsprung disease

Abstract

Objective To compare the clinical and imaging findings of children with Hirschsprung’s disease and allied Hirschsprung’s disease. Methods A total of 80 children with Hirschsprung’s disease and allied Hirschsprung’s disease who were admitted to the Department of Radiology of Shanxi Children’s Hospital from September 2014 to October 2019 were selected as the subjects of this study. According to the results of pathological examination, they were divided into group A (children with Hirschsprung’s disease, n=37) and group B (children with allied Hirschsprung’s disease, n=43). The clinical data of patients in group A and group B were analyzed retrospectively. Both groups received X-ray and barium enema before pathological examination. The clinical data, X-ray and barium enema results were compared and analyzed. Results There was no significant difference in sex, mean age, gestational age, delivery mode, clinical manifestation, anal examination between the two groups (P>0.05). In group A, the proportion of transitional segment (83.78%) was significantly higher than that in group B (6.98%), the proportion of irregular contraction in group A (37.84%) was significantly lower than that in group B (88.37%), the difference was statistically significant (P 0.05); the residual sites of barium between the two groups after 24 hours of barium enema were compared, the differences were not statistically significant (P>0.05); the diameter of colon between the two groups was compared, the difference was not statistically significant (P>0.05); the angle between the dilated segment and the transitional segment/spasm segment was larger in group A than that in group B (P<0.05). Conclusions The clinical data of children with Hirschsprung’s disease and allied Hirschsprung’s disease are similar, but there are significant differences between them by X-ray barium enema. Key words: Hirschsprung disease; Allied Hirschsprung disease; Clinical manifestation; Imaging findings