Central Plains Medical Journal最新文献

{"title":"Effects of large dose of statins on renal function, vascular endothelial function and levels of inflammatory factor in patients with coronary heart disease complicated with renal insufficiency","authors":"Ai-jie Hou, Wen-guang Li, H. Xue","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.031","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.031","url":null,"abstract":"Objective \u0000To analyze the effects of large dose of rosuvastatin on renal function, vascular endothelial function and levels of inflammatory factor in patients with coronary heart disease complicated with renal insufficiency. \u0000 \u0000 \u0000Methods \u0000Sixty patients with coronary heart disease complicated with renal insufficiency admitted to the Second People’s Hospital from January 2015 to December 2018 were randomly divided into the control group and study group by random number table method, with 30 patients in each group. Patients in the control group were treated with conventional dose of rosuvastatin, and patients in the study group were treated with large dose of rosuvastatin. The renal function, vascular endothelial function, levels of inflammatory factor and incidence of adverse reactions were compared between the two groups. \u0000 \u0000 \u0000Results \u0000There was no significant difference in 24 h urinary protein or serum creatinine between the two groups before treatment (P>0.05); after treatment, the levels of 24 h urinary protein and serum creatinie decreased in both groups, and the study group had higher 24 h urinary protein level than the control group (P 0.05). After treatment, Hcy levels decreased, but NO and eNOS levels increased in both groups; compared to control group, and the Hcy levels in the study group were lower, while NO and eNOS levels were higher (P 0.05). The incidence of adverse reaction of the study group was 33.33% (10/30), higher than the 26.67% (8/30) of the control group, but there was no significant difference in incidence of adverse reactions between the two groups (P>0.05). \u0000 \u0000 \u0000Conclusions \u0000Large dose of rosuvastatin in the treatment of patients with coronary heart disease and renal insufficiency can significantly improve renal function and vascular endothelial function, and reduce inflammation levels, without increasing incidence of adverse reactions. \u0000 \u0000 \u0000Key words: \u0000Large dose; Statins; Coronary heart disease; Renal insufficiency; Renal function; Vascular endothelial function; Inflammatory factors","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"85 1","pages":"103-105"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89013597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of effects of etomidate versus midazolam on hemodynamics and protection of myocardium during tracheal intubation in patients undergoing off-pump coronary artery bypass grafting","authors":"Teng Hu, Zhanjun Zhang, Ren-Chao Liu, Huai-jin Cheng, Ran Li, Jia Shi","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.026","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.026","url":null,"abstract":"Objective \u0000To investigate the effects of etomidate and midazolam on hemodynamics and protection of myocardium during tracheal intubation in patients undergoing off-pump coronary artery bypass grafting (OPCAB). \u0000 \u0000 \u0000Methods \u0000Seventy-eight patients with OPCAB hospitalized in Jiaozuo People’s Hospital from January 2017 to July 2019 were selected, and they were divided into etomidate group (group A, 39 cases) and midazolam group (group B, 39 cases) according to the random number table method. Group A and group B were intravenously injected with etomidate and midazolam respectively; and both groups were intravenously injected with fentanyl + pipecuronium bromide for anesthesia induction, and then were given propofol + piperacium bromide + fentanyl for anesthesia maintenance. The hemodynamics, such as heart rate (HR), mean arterial pressure (MAP), mean pulmonary artery pressure (MPAP), pulmonary artery wedge pressure (PAWP), vascular resistance, such as systemic vascular resistance index (SVRI), pulmonary vascular resistance index (PVRI), and oxygen metabolism, such as mixed venous oxygen saturation (SvO2), oxygen supply index (DO2I), oxygen consumption index (VO2I), were monitored during anesthesia. The above indicators were recorded before tracheal intubation (T0), after intubation immediately (T1), at 1 min after intubation (T2), 5 min after intubation (T3) and 10 min after intubation (T4). Serum cardiac troponin I (cTnI) level was measured before anesthesia, at the end of surgery and at 6, 12 and 24 h after surgery. \u0000 \u0000 \u0000Results \u0000Compared with levels at T0, the HR and MAP were increased at T1 and T2 in both groups, and the HR in group A was lower than that in group B (P 0.05). Compared with levels before anesthesia, the serum cTnI levels in the two groups were increased at the end of surgery and at 6, 12 and 24 h after surgery (P 0.05). \u0000 \u0000 \u0000Conclusions \u0000Compared with midazolam, etomidate is more beneficial to sustaining hemodynamic stability during tracheal intubation in patients with OPCAB during anesthesia induction, and their roles in oxygen metabolism balance and myocardial protection are comparable. \u0000 \u0000 \u0000Key words: \u0000Etomidate; Midazolam; Off-pump coronary artery bypass grafting; Hemodynamics; Vascular resistance; Myocardial injury","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"15 1","pages":"87-91"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84333755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of detection of creatine kinase isoenzyme mass by immunoturbidimetry in the diagnosis of acute myocardial infarction","authors":"Lixia Zhang, Mao Lu, Haixia Du","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.020","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.020","url":null,"abstract":"Objective \u0000To investigate the value of determination of creatine kinase isoenzyme (CKMB) mass by immunoturbidimetry in the diagnosis of acute myocardial infarction. \u0000 \u0000 \u0000Methods \u0000A total of 150 patients with acute myocardial infarction (AMI) admitted to Jincheng General Hospital from June 2018 to June 2019 were enrolled into the observation group. And 150 healthy persons who underwent physical examination in the same period were selected as the control group. Serum levels of cardiac troponin T (cTnT), myoglobin (MYO) and CKMB mass in the two groups were compared. CKMB mass levels in the observation group were measured by electrochemiluminescence and immunoturbidimetry. And the positive detection rates of the two methods were compared. \u0000 \u0000 \u0000Results \u0000The serum cTnT, MYO and CKMB mass levels in the observation group were significantly higher than those in the control group (P 0.05). There was no significant difference in positive rate of CKMB mass between electroluminescence (96.00%, 144/150) and immunoturbidimetry (94.67%, 142/150), P>0.05. \u0000 \u0000 \u0000Conclusions \u0000The detection of CKMB mass is of great significance for the diagnosis of AMI. The results of immunoturbidimetric method in detecting CKMB mass are not significantly different from the electrochemical luminescence, but the former is more suitable for the development of primary hospitals and has a high positive detection rate. \u0000 \u0000 \u0000Key words: \u0000Acute myocardial infarction; Creatine kinase isoenzyme mass; Immunoturbidimetry; Electrochemiluminescence","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"7 1","pages":"67-69"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87480945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-invasive diagnosis of ulcerative colitis","authors":"Lei Lu, Lingbin Kong","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.035","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.035","url":null,"abstract":"Ulcerative colitis (UC) is a kind of chronic and recurrent abnormal immune-mediated intestinal inflammatory enteropathy by various causes. At present, the diagnosis of the disease mainly depends on the clinical manifestations, colonoscopy and biopsy. This diagnosis method is traumatic, time-consuming, expensive, which is difficult to be popularized. The latest research has found that biochemical markers, tomography and gene marker detection have certain diagnostic value for UC, and non-invasive. Now, the non-invasive diagnostic methods of UC are summarized as follows. \u0000 \u0000Key words: \u0000Colitis, ulcerative; Biochemical markers; Tomography; Genetic markers; Diagnosis","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"1 1","pages":"118-122"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79729999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of aspirin combined with atorvastatin on hypertensive patients with diabetes mellitus","authors":"Hongli Xing, Lifang Wang, Mei Ping, Yongping Jia","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.033","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.033","url":null,"abstract":"Objective \u0000To investigate the effects of aspirin combined with atorvastatin on hypertensive patients with diabetes mellitus. \u0000 \u0000 \u0000Methods \u0000One hundred hypertensive patients with diabetes mellitus admitted to the First Hospital of Shanxi Medical University from January 2016 to December 2017 were selected and divided into aspirin group and aspirin combined with atorvastatin group (combined treatment group) according to random number table method, with 50 cases in each group. Patients in aspirin group were treated with aspirin, 100 mg/d; while patients in combined treatment group were treated with aspirin, 100 mg/d, and atorvastatin, 20 mg/d. Blood lipid, urinary albumin, β2-microglobulin (β2-MG), urinary albumin excretion rate (UAER), cardioankle vascular index (CAVI) and ankle brachial index (ABI) of the two groups were measured and compared before and 20 weeks after treatment, and the incidences of non fatal myocardial infarction of the two groups were compared and analyzed by follow-up. \u0000 \u0000 \u0000Results \u0000Compared with preoperative levels, the levels of total cholesterol and low-density lipoprotein cholesterol of the two groups were reduced, and the levels of CAVI and ABI were improved after treatment (P 0.05). However, the urinary albumin, triacylglycerol, UAER and β2-MG in the combined treatment group were decreased after treatment (P<0.05). During the median follow-up period, the incidence of major endpoints in non fatal myocardial infarction in aspirin group was higher than that in combined treatment group (P<0.05). Multiple stepwise regression analysis showed that the risk factors of arterial stiffness and microalbuminuria were diastolic pressure, systolic pressure, 2 h postprandial blood glucose and fasting blood glucose. \u0000 \u0000 \u0000Conclusions \u0000The combined use of aspirin and atorvastatin can significantly reduce the level of urinary microprotein in patients with hypertension and diabetes mellitus, alleviate arterial stiffness, effectively reduce the incidence of non fatal myocardial infarction. And the study finds that arterial stiffness and microalbuminuria are directly related to blood pressure and blood glucose level. \u0000 \u0000 \u0000Key words: \u0000Aspirin; Atorvastatin; Hypertension; Diabetes mellitus; Arterial stiffness; Non fatal myocardial infarction","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"82 1","pages":"110-114"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82483734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical analysis of 200 cases of cervical intraepithelial neoplasia","authors":"Lina Xu","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.017","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.017","url":null,"abstract":"Objective \u0000To investigate the diagnosis and treatment of cervical intraepithelial neoplasia (CIN). \u0000 \u0000 \u0000Methods \u0000The clinical records and data of 200 patients with CIN diagnosed and treated in Shanxi Provincial People’s Hospital from January 2017 to January 2018 were retrospectively analyzed. All patients were diagnosed by three-step screening of the cervix, including thin-prep liquid-based cytology test (TCT) and/or human papilloma virus (HPV) detection, colposcopy and histopathology of the cervix. Loop electrosurgical excision procedure (LEEP) was performed according to patient’swillingness and HPV infection condition to diagnose cervix. For patients with cervical cancer diagnosed by patholgical examination, total laparoscopic extrafascial hysterectomy was performed. The TCT examination of cervix, colposcopy biopsy, operation and 1-year follow-up of all patients were observed. \u0000 \u0000 \u0000Results \u0000A total of 141 cases of low-grade squamous intraepithelial lesion (LSIL) and high-grade squamous intraepithelial lesion (HSIL) were detected by TCT of cervix among 200 CIN patients, and the diagnostic coincidence rate of TCT was 70.50%; while a total of 63 cases of CIN Ⅱ and CIN Ⅲ were detected by histopathology, and 45 cases of HSIL were detected by TCT, the diagnostic coincidence rate of TCT was 71.42%; 137 cases of CIN Ⅰ were detected by histopathology, 96 cases of LSIL were detected by TCT, and the diagnostic coincidence rate of TCT was 70.07%. A total of 163 cases of LSIL and HSIL were determined by colposcopy in 200 CIN patients, with the diagnostic accuracy of 81.50%; 63 cases of CIN Ⅱ and CIN Ⅲ were determined by histopathology, while 50 cases of HSIL were determined by colposcopy, with the diagnostic accuracy of 79.36%; 137 cases of CIN Ⅰ were determined by histopathology, and 113 cases of LSIL were determined by colposcopy, with the diagnostic accuracy of 82.48%. Among the 137 LSIL patients confirmed by histopathology, with cytological examination results showing cannot exlude high-grade squamous intraepithe lial lesion, aged over 45 years, and with lesions lasting for over 1 year, 52 patients underwent diagnostic LEEP operation. Among the 63 cases of HSIL confirmed by histopathology, 58 cases were treated by LEEP. Among the 63 HSIL patients, 5 patients with positive examination results in margin were given cytology + HPV + colposcopy every 6 months; and 4 of 5 patients were diagnosed as cervical cancer IA 1 stage by pathology, then the 4 patients were treated by total laparoscopic extrafascial hysterectomy after LEEP. Up to the end of 12-month follow-up, no CIN residue or cervical cancer recurrence was detected, but there were 8 cases of CIN recurrence. \u0000 \u0000 \u0000Conclusions \u0000Early diagnosis of precancerous cervical lesions and timely development of reasonable treatment are the key points to prevent and treat cervical cancer. \u0000 \u0000 \u0000Key words: \u0000Diagnosis; Precancerous cervical lesions; Treatment; Clinical analysis","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"27 5","pages":"57-60"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72607797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Levels and significance of pepsinogen, gastrin 17 in serum in patients with chronic atrophic gastritis","authors":"H. Su","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.010","url":null,"abstract":"Objective \u0000To analyze the levels of serum pepsinogen, gastrin 17 (G-17) in patients with chronic atrophic gastritis and their clinical significance. \u0000 \u0000 \u0000Methods \u0000A total of 196 patients with gastroduodenal disease who underwent gastroscopy in Linfen Central Hospital from January 2016 to January 2019 were selected as the study objects. According to the results of gastroscopy, they were divided into chronic atrophic gastritis group and non-atrophic gastritis group, with 98 cases in each group. The patients in chronic atrophic gastritis group were further divided into atrophic gastric body inflammation group (34 cases), atrophic gastric antrum inflammation group (42 cases), and the whole atrophic gastric multifocal gastritis group (22 cases) according to the lesion sites. The levels of serum pepsinogen Ⅰ (PG Ⅰ), pepsinogen Ⅱ (PG Ⅱ) and G-17 were measured by enzyme-linked immunosorbent assay. And pepsinogen ratio (PGR), PG Ⅰ/PG Ⅱ, was calculated. Qualitative detection of Helicobacter pylori (Hp) was performed by 13C urea breath test. The levels of PGⅠ, PGⅡ, PGR, and G-17 in each group were analyzed and compared among groups. \u0000 \u0000 \u0000Results \u0000The levels of serum PG Ⅰ and G-17 in the chronic atrophic gastritis group were significantly lower than those in the non-atrophic gastritis group (P 0.05), the difference in PGR between the two groups was statistically significant (P 0.05). \u0000 \u0000 \u0000Conclusions \u0000Decreased levels of PGⅠ, PGR and G-17 are biological markers of chronic atrophic gastritis. Large-scale population screening and screening for chronic atrophic gastritis can be performed based on serum PGⅠ and PGR cutoffs, and further examination with gastroscopy can improve the early diagnostic rate of gastric cancer. \u0000 \u0000 \u0000Key words: \u0000Stomach neoplasms; Chronic atrophic gastritis; Pepsinogen I; Pepsinogen Ⅱ; Gastrin 17; Pepsinogen ratio","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"29 1","pages":"33-36"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73902225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between bacterial infection and pancreatic leakage after pancreaticoduodenectomy","authors":"Xu Jian, Miao Yu, Quan Shen, Jia Meng","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.005","url":null,"abstract":"Objective \u0000To analyze the relationship between postoperative infection and pancreatic leakage after pancreaticoduodenectomy, and to provide a reference and guidance for the application of antibiotics postoperative. \u0000 \u0000 \u0000Methods \u0000A total of 400 patients treated by pancreaticoduodenectomy from July 2014 to December 2018 in Henan Provincial People’s Hospital were enrolled. According to the severity of pancreatic leakage and pancreatic fistula, all patients were divided into non pancreatic fistula group (250 cases), biochemical leakage group (98 cases) and B/C pancreatic fistula group (52 cases). The postoperative infection, occurrence and severity of pancreatic leakage were counted. And the relationship between bacterial infection and pancreatic leakage was analyzed. \u0000 \u0000 \u0000Results \u0000Among the three groups, the bacterial infection rate was 4.00% (10/250) in the non pancreatic fistula group, 18.36% (18/98) in the biochemical leakage group, and 90.38% (47/52) in the B/C pancreatic fistula group, and the difference was statistically significant among the three groups (all P<0.05). In the B/C pancreatic fistula group, there were 40 patients with B-level pancreatic leakage, of which 36 patients had positive bacterial culture; and 12 patients in this group were with C-level pancreatic leakage, of which 11 patients were with positive bacterial culture. There was a significant difference in bacterial infection between B-level and C-level pancreatic fistula patients (P<0.05). Among the patients with positive result of bacterial culture within one week after operation, there were 15 cases with grade B pancreatic leakage and 9 cases with grade C pancreatic leakage; among the patients with positive result of bacterial culture one week after operation, 21 patients had grade B pancreatic leakage and 2 patients had grade C pancreatic leakage. There was no significant difference in the bacterial spectrum of patients with pancreatic leakage at different stages. \u0000 \u0000 \u0000Conclusions \u0000Bacterial infection is a risk factor for pancreatic leakage after pancreaticoduodenectomy, and the earlier the bacterial infection occurs, the worse the pancreatic leakage progress. \u0000 \u0000 \u0000Key words: \u0000Pancreaticoduodenectomy; Bacteria infection; Pancreatic leakage","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"46 1","pages":"16-18"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85464145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic management of foreign bodies in the upper gastrointestinal tract: a retrospective study on 570 cases","authors":"Xiaodi Jing, Xuexiu Zhang, Xiaofang Guo, B. Gao, Jianning Yao, Chunfeng Wang, Lian-feng Zhang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.007","url":null,"abstract":"Objective \u0000To investigate the pathogenesis and treatment of foreign bodies in the upper digestive tract in the Central Plain of China. \u0000 \u0000 \u0000Methods \u0000A total of 570 patients with foreign bodies in the upper gastrointestinal tract treated in the First Affiliated Hospital of Zhengzhou University from March 2015 to March 2019 were selected. The types of foreign bodies, location of impaction, complications, selection of instruments and methods of removal of them were analyzed retrospectively. \u0000 \u0000 \u0000Results \u0000Among the 570 patients, 323 persons were males and 247 persons were females, with an average age of 47 years. Date pits were the most common ingested foreign bodies (24.2%, 138/570), and the esophagus was the most common lodgment site (73.2%, 417/570). Time from foreign incarceration to treatment was 6 h to 30 d, and the average hospitalization rate was 62.3% (339/570). The primary clinical symptom was retrosternal pain. The complication rate was (58.1%, 331/570), which was relatively high. Two patients underwent surgery to remove foreign bodies for esophageal perforation, and one pationt died due to treatment failure. \u0000 \u0000 \u0000Conclusions \u0000Endoscopic management is a safe and highly effective procedure for extracting ingested foreign bodies. Rapid endoscopic intervention should be provided to reduce the risk of complications. \u0000 \u0000 \u0000Key words: \u0000Foreign body; Upper digestive tract; Endoscopy","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"1 1","pages":"22-24"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76746268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of detection values of acid-fast bacilli in sputum by direct smear versus liquid-based cytology smear","authors":"Wenzhe Wu, X. Tian","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.018","url":null,"abstract":"Objective \u0000To compare the detection values of direct smear and liquid-based cytology smear in the detection of acid-fast bacilli in sputum. \u0000 \u0000 \u0000Methods \u0000A total of 4 000 patients with tuberculosis admitted to Binzhou Central Hospital from May 2018 to May 2019 were selected. One sputum sample at night and one sputum sample at morning were collected from every patients. Finally, 8 000 specimens were enrolled in the study in total. Direct smear method and liquid-based cytology smear method were used to detect the 8 000 specimens. And the positive detection rates of acid-fast bacilli in sputum by two methods were recorded. \u0000 \u0000 \u0000Results \u0000The positive detection rates of acid-fast bacilli in the morning sputum sample by liquid-based cytology smear and direct smear were 30.33% (2 426/4 000) and 21.55% (1 724/4 000), respectively, and the positive detection rates of the night sputum samples by the two methods were 22.34% (1 787/4 000) and 12.40% (992/4 000) respectively. Compared with the night sputum samples, the positive detection rates of acid-fast bacilli in the morning sputum samples by two detection methods were higher, and the difference was statistically significant (P<0.05). Compared with direct smear method, the positive rates of acid-fast bacilli in the morning sputum samples and in the night sputum samples detected by liquid-based cytology smear method were higher, and the difference was statistically significant (P<0.05). Among the 8 000 specimens, the positive rates of salivary sputum, mucus sputum, blood sputum and purulent sputum detected by liquid-based cytology smear method were 14.52% (108/744), 12.09% (429/3 548), 65.49% (334/510) and 49.00% (1 567/3 198), respectively, And the positive detection rates of salivary sputum, mucus sputum, blood sputum and purulent sputum detected by direct smear method were 2.96% (22/744), 8.26% (293/3 548), 42.35% (216/510) and 36.34% (1 162/3 198), respectively. Compared with salivary sputum, mucus sputum and purulent sputum, the positive detection rates of acid-fast bacilli in blood sputum by the two methods were higher, and the difference was statistically significant (P<0.05). Compared with the direct smear method, the positive detection rates of sputum, mucus sputum, blood sputum and purulent sputum by liquid based cytology smear method were higher, and the difference was statistically significant (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The application of liquid-based cytology smear in the detection of acid-fast bacilli in sputum can effectively diagnose pulmonary tuberculosis and provide a basis for clinical diagnosis and treatment. \u0000 \u0000 \u0000Key words: \u0000Tuberculosis; Mycobacterium tuberculosis; Liquid-based cytology smear; Detection technology of acid-fast bacilli","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"1 1","pages":"60-63"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84268877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}