Value of detection of creatine kinase isoenzyme mass by immunoturbidimetry in the diagnosis of acute myocardial infarction

Abstract

Objective To investigate the value of determination of creatine kinase isoenzyme (CKMB) mass by immunoturbidimetry in the diagnosis of acute myocardial infarction. Methods A total of 150 patients with acute myocardial infarction (AMI) admitted to Jincheng General Hospital from June 2018 to June 2019 were enrolled into the observation group. And 150 healthy persons who underwent physical examination in the same period were selected as the control group. Serum levels of cardiac troponin T (cTnT), myoglobin (MYO) and CKMB mass in the two groups were compared. CKMB mass levels in the observation group were measured by electrochemiluminescence and immunoturbidimetry. And the positive detection rates of the two methods were compared. Results The serum cTnT, MYO and CKMB mass levels in the observation group were significantly higher than those in the control group (P 0.05). There was no significant difference in positive rate of CKMB mass between electroluminescence (96.00%, 144/150) and immunoturbidimetry (94.67%, 142/150), P>0.05. Conclusions The detection of CKMB mass is of great significance for the diagnosis of AMI. The results of immunoturbidimetric method in detecting CKMB mass are not significantly different from the electrochemical luminescence, but the former is more suitable for the development of primary hospitals and has a high positive detection rate. Key words: Acute myocardial infarction; Creatine kinase isoenzyme mass; Immunoturbidimetry; Electrochemiluminescence