Caries Research最新文献

{"title":"Potential of Digital Approaches in Evaluating Rodent Caries.","authors":"Ruqian Yang, Hafeza Chowdhury, Saishaa Gupta, Yuan Liu, Xingyi Lu, Nora Alomeir, TongTong Wu, Yan Wu, Jin Xiao","doi":"10.1159/000550287","DOIUrl":"10.1159/000550287","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to assess the sensitivity, specificity, and accuracy of a digital-based method for caries assessment in a rodent model, compared to a conventional modified-Keyes method.</p><p><strong>Methods: </strong>One hundred and eight mandible molars of Sprague-Dawley rats were collected from a cariogenic caries rodent model, including both caries-free and carious teeth. Smooth surfaces were evaluated using digital photography, whereas sulcal lesions and volumetric quantification were assessed with micro-CT and the Amira software. In the conventional assessment, smooth surfaces were examined under a stereomicroscope with tactile probing, and sulcal surfaces were evaluated on stained, sectioned teeth. Sensitivity, specificity, and accuracy of the digital approaches were calculated, with the conventional method serving as the gold standard. Spearman correlation analysis was conducted between conventional enamel caries scores, combined digital (photography and micro-CT) enamel caries scores, and micro-CT quantified remaining enamel volume.</p><p><strong>Results: </strong>A total of 107 <sc>m</sc> were available for smooth surfaces evaluation, and 98 <sc>m</sc> were included for sulcal surfaces, tooth-level caries detection and enamel lesion assessments. For smooth surfaces, the digital photographic method demonstrated an accuracy of 88.0%, with a sensitivity of 88.8% and a specificity of 85.7%. In the evaluation of sulcal caries, Micro-CT analysis achieved an accuracy of 96.9%, with 100% sensitivity and 87.0% specificity. For tooth-level caries detection, the combined digital approaches of smooth surface photography and sulcal micro-CT slicing achieved 96.9% accuracy, 97.6% sensitivity, and 92.9% specificity.</p><p><strong>Conclusions: </strong>This study demonstrates the efficacy of digital photography and micro-CT in the caries assessment of rodent models. The findings support the establishment of a standardized, nondestructive imaging protocol to enhance consistency in caries research.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-10"},"PeriodicalIF":2.6,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12860558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145877703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Approaches and Treatment Strategies for Deep Carious Lesions among Dentists in Egypt and Saudi Arabia: A Questionnaire-Based Cross-Sectional Study.","authors":"Marwa Baraka, Nourhan Aly, Passent Ellakany, Hisham Abada, Margherita Fontana","doi":"10.1159/000549788","DOIUrl":"10.1159/000549788","url":null,"abstract":"<p><strong>Introduction: </strong>The study objective was to assess and compare the use of diagnostic methods, clinical decision-making, treatment strategies, and attitudes of general dentists, pediatric dentists, and endodontists regarding deep carious lesions (DCL) in Egypt and Saudi Arabia.</p><p><strong>Methods: </strong>A cross-sectional multinational study was conducted in Egypt and Saudi Arabia (January 2023-June 2024). A validated online questionnaire was distributed to 1,000 dentists (734 Egypt; 266 Saudi Arabia), including general practitioners, pediatric dentists, and endodontists. The survey covered demographics, diagnostics, clinical scenarios, treatment strategies, and influencing factors. Data were analyzed using SPSS v26 with descriptive statistics, chi-square tests, and logistic regression (p < 0.05).</p><p><strong>Results: </strong>A total of 500 dentists responded (response rate of 46.0% for Egypt [338/734] and 60.9% for Saudi Arabia [162/266]). Most participants were general practitioners (60.4%) and female (57.8%), with an average of 9 years of clinical experience. Selective caries removal was preferred by 23.2% of general practitioners, 34.2% of pediatric dentists, and 21.8% of endodontists. Multivariable regression analysis showed that selective caries removal was more likely to be chosen by pediatric dentists (adjusted odds ratio [AOR] = 1.38, p = 0.04), dentists practicing in Egypt (AOR = 2.70, p < 0.001), and those who had attended MID courses (AOR = 1.75, p < 0.001). Endodontists demonstrated greater adherence to evidence-based guidelines (AOR = 3.35, p < 0.001), whereas practicing in Egypt (AOR = 0.43, p = 0.002), having more years of experience (AOR = 0.94, p = 0.001), and attending MID courses (AOR = 0.57, p = 0.03) were associated with lower odds of adherence.</p><p><strong>Conclusions: </strong>Pediatric dentists, practitioners in Egypt, and those with training in minimally invasive dentistry were more likely to favor selective caries removal, whereas endodontists demonstrated the highest adherence to AAE guidelines and tended to prefer more invasive treatment strategies. Despite strong evidence supporting conservative approaches for managing DCLs in vital teeth, invasive strategies were still commonly reported among respondents. Greater implementation of evidence-based, patient-centered treatment strategies is needed among dentists in Egypt and Saudi Arabia.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-12"},"PeriodicalIF":2.6,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145877655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous Evaluation of Three Alternative Models to Animal Caries Testing for Assessing the Anticaries Efficacy of Monofluorophosphate Dentifrices.","authors":"Malgorzata Klukowska, Tiffany Hare, Michael A Kaminski, Nataliya Gurich, Julie M Grender, Aaron R Biesbrock, Eva Schneiderman, Anderson T Hara, Domenick T Zero, Samuel St John","doi":"10.1159/000550119","DOIUrl":"10.1159/000550119","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to simultaneously assess three alternative models to animal caries testing - an in situ remineralization model, an in vivo salivary fluoride clearance model, and a modified in vitro pH cycling model - for measuring the anticaries efficacy of dentifrices containing monofluorophosphate (MFP) up to 2,800 ppm F.</p><p><strong>Methods: </strong>A series of MFP dentifrices were prepared at 250, 1,100, and 2,800 ppm F as MFP in a silica abrasive base with a placebo toothpaste (fluoride-free). Model #1: in a randomized crossover trial, in situ remineralization (% surface microhardness recovery of partially demineralized enamel) and enamel fluoride uptake (microbiopsy) were assessed over 7, 14, and 21 days in 15 participants. Model #2: in vivo salivary fluoride clearance was evaluated in 26 participants using a randomized, crossover design by measuring salivary fluoride concentration over 30 min following 2 min of brushing. Model #3: a modified in vitro pH cycling model with pre-hydrolyzed (2N HCl) MFP dentifrice supernatants was used to evaluate lesion progression over 19 days with 6 h demineralization and 17 h remineralization daily (Monday-Friday with weekend remineralization) and twice daily morning and afternoon 2-min dentifrice slurry treatments on 10 teeth per dentifrice.</p><p><strong>Results: </strong>There was a statistically significant impact of dose (p < 0.001) observed in all three models, and the three models are highly correlated with one another and with animal caries testing results (Spearman's ρ > 0.77, p < 0.0001). In situ hardening, fluoride uptake, and fluoride area under the curve clearance showed linear relationships with MFP dose. Acid hydrolysis successfully liberated ionic fluoride and lesion progression in pH cycling was exponentially suppressed with fluoride dose.</p><p><strong>Conclusion: </strong>The in situ, in vivo, and modified in vitro models each provided dose-responsive and sensitive measures of MFP activity. Importantly, the modification of pH cycling for MFP hydrolysis enabled a well-developed laboratory protocol to be adapted to an important fluoride source. These approaches appear to offer viable alternatives to animal caries models for evaluating the efficacy of MFP-containing dentifrices and each could be chosen in different settings to understand the impact of MFP-containing dentifrices on caries prevention.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-11"},"PeriodicalIF":2.6,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145809623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caries Detection in Primary Molars with Bitewing Radiographs through Deep Learning Based-Object Detectors.","authors":"Zhi Qin Tan, Ilana Felix Pinho, Ryan Banks, Xiongjie Chen, Laura Regina Antunes Pontes, Mariana Minatel Braga, Fausto Medeiros Mendes, Yunpeng Li","doi":"10.1159/000550079","DOIUrl":"10.1159/000550079","url":null,"abstract":"<p><strong>Introduction: </strong>Automated methods for caries detection among children can help triage children with greater need for treatment and assist clinicians in achieving a more accurate diagnosis of caries lesions. Therefore, we aimed to develop artificial intelligence algorithms based on various object detectors for detecting and staging caries lesions in primary molars using bitewing radiographs.</p><p><strong>Methods: </strong>We used a dataset of 1,023 bitewing radiographs of primary molars from children aged 3-10 years. The radiographs were annotated by two examiners using a dedicated annotation platform to draw bounding boxes corresponding to four different primary caries severity stages. Five popular deep learning object detection algorithms were trained to detect the annotated caries and evaluated with various performance metrics, considering three different thresholds: all lesions, dentine caries lesions, and dentine caries lesions requiring operative treatment.</p><p><strong>Results: </strong>For staging caries lesions, the DINO model achieved higher concordance with a weighted kappa score of 0.713 on the test dataset, outperforming other object detectors. The DINO model achieved the highest sensitivity for detecting all caries lesions (0.509) while also attaining the highest sensitivity and accuracy in identifying dentine caries requiring operative treatment, at 0.659 and 0.980, respectively. However, YOLOv7 also achieved good performance, with specificity values exceeding 0.99 and accuracy values exceeding 0.92 across all thresholds.</p><p><strong>Conclusions: </strong>The DINO and YOLOv7 algorithms perform well at detecting caries on primary molars in bitewings, highlighting their potential for clinical application at aiding clinicians in daily practice.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-9"},"PeriodicalIF":2.6,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145780290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are Area-Level Socioeconomic Factors Associated with Dental Caries and Tooth Loss? A Systematic Review.","authors":"Mariél de Aquino Goulart, Rafaela Soares Rech, Mario Vianna Vettore, Roger Keller Celeste","doi":"10.1159/000550120","DOIUrl":"10.1159/000550120","url":null,"abstract":"<p><strong>Introduction: </strong>Area-level socioeconomic factors are within the social determinants of health, encompassing conditions in which people are born, grow, live, work, and age, which influence health beyond individual characteristics. This review examined the association between area-level socioeconomic factors and dental caries and tooth loss. The hypothesis was that individuals residing in more socioeconomically deprived areas experience higher odds of dental caries and tooth loss, independent of individual socioeconomic status.</p><p><strong>Methods: </strong>A systematic search was conducted in PubMed, Scopus, Embase, and Web of Science. Studies reporting clinical or self-reported dental caries or tooth loss and evaluating area-level socioeconomic deprivation or income (neighbourhood, municipality, or region) using multilevel models were included.</p><p><strong>Results: </strong>Of 4,671 screened records, 44 studies (41 cross-sectional) published from 2006 to 2024 were included. The most common exposures were area socioeconomic deprivation indices (n = 24), area average income (n = 21), and the Human Development Index (HDI) (n = 13). Quantitative synthesis was precluded by heterogeneity of aggregation levels, outcomes (tooth loss, caries experience, and untreated caries), and outcome measurement (dichotomous/continuous). Most studies adjusted for individual-level socioeconomic factors (82%). The hypothesised association was most consistent for tooth loss (e.g., functional dentition or edentulism, 6/6 studies), at a medium level of aggregation (13/15), and for the HDI (10/13). Studies using ordered categories frequently demonstrated clear socioeconomic gradients.</p><p><strong>Conclusion: </strong>The findings support the hypothesis that residing in more affluent areas is associated with better oral health outcomes, specifically lower levels of tooth loss and, to a lesser extent, dental caries, after adjusting for individual-level socioeconomic factors.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-14"},"PeriodicalIF":2.6,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145780261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Erosive Tooth Wear and Sociodemographic Background Factors, Restorative Dental Treatment Need, and Periodontal Health among Young Finnish Men: A Cross-Sectional Epidemiological Study.","authors":"Pernelle Moilanen, Antti Kämppi, Jari Päkkilä, Mika Huttunen, Sari Räsänen, Annakaisa Muhonen, Pertti Patinen, Leo Tjäderhane, Vuokko Anttonen, Tarja Tanner","doi":"10.1159/000549983","DOIUrl":"10.1159/000549983","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to determine the level of erosive tooth wear (ETW) in young, healthy Finnish men in relation to their sociodemographic background; the number of decayed, missing due to caries, and filled teeth in their permanent dentition (DMFT); and Community Periodontal Index (CPI). Studies on the association between ETW and periodontal health, as well as those related to sociodemographic factors, have so far been inconclusive, indicating a need for further research on these associations.</p><p><strong>Methods: </strong>The data used in this study were collected from the database of the \"Oral Health of Finnish Conscripts 2021\" project, including clinical and survey data from healthy Finnish males (n = 1,712) in their early twenties. Basic Erosive Tooth Wear Examination (BEWE) scoring was used to evaluate the ETW level. Distributions and mean BEWE sum score values excluding wisdom teeth were calculated. Cross-tabulation together with a χ2 test and binary logistic regression analysis were used to evaluate increased risk (BEWE sum score ≥3) for ETW. A geomap was used to illustrate the prevalence and severity of ETW across various regions of Finland.</p><p><strong>Results: </strong>ETW is common among young Finnish men as almost two-thirds (63.0%) of the subjects had signs of erosive lesions. Severe ETW (BEWE sum score ≥9) was rare (3.2%). More severe ETW was associated with poorer overall oral health as the DMFT and CPI values were both higher with an exacerbated level of erosion. Restorative treatment need (D >0) and periodontal treatment need (CPI ≥2) were also associated with ETW. Living in urban areas and older age were associated with a higher prevalence and severity of ETW. A distinct variation in the increased risk for ETW was observed between various regions of Finland.</p><p><strong>Conclusion: </strong>Poorer dental and periodontal health, as well as place of residence, were associated with higher severity of ETW. The progressive and irreversible nature of the condition underscores the importance of early detection.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-11"},"PeriodicalIF":2.6,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145780306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental Caries in Preschool Twins: Coincidences, Heritability, and Associated Factors in a Cross-Sectional Census-Based Study.","authors":"Letícia Caminha Aguiar Lopes, Francisca Aline da Silva Matias-Santos, Maria Eduarda Matos Sousa, Viviane Oliveira do Nascimento, Marta Maria Alves Pereira, Cacilda Castelo Branco Lima, Lúcia de Fátima Almeida de Deus Moura, Marina de Deus Moura de Lima, Marcoeli Silva de Moura","doi":"10.1159/000549992","DOIUrl":"10.1159/000549992","url":null,"abstract":"<p><strong>Introduction: </strong>Dental caries is a sugar-dependent biofilm disease influenced by multiple factors, yet the genetic contribution to its development remains a subject of debate.</p><p><strong>Methods: </strong>A cross-sectional census study was conducted with preschool children aged from 3 to 5 years old in Teresina, Brazil. Twin pairs (monozygotic [MZ] or dizygotic [DZ]) with complete or mixed primary dentition up to the eruption of the permanent lower incisors were included. Uncooperative children were excluded. Data were collected through questionnaires and clinical examinations using the ICDAS index. Tetrachoric correlations and multinomial logistic regression were used to assess coincidences. Multilevel Poisson regression identified associated factors (p < 0.05).</p><p><strong>Results: </strong>Of the 325 eligible twin pairs, 219 (67.4%) participated in the data collection (87 MZ and 132 DZ). MZ twins exhibited a strong positive correlation for the presence of any lesion (rMZ = 0.776) and a very strong positive correlation for ICDAS 4+ lesions (rMZ = 0.920). DZ twins exhibited a moderate positive correlation for any lesion (rDZ = 0.581) and a strong positive correlation for ICDAS 4+ lesions (rDZ = 0.634). Environmental variables explained up to 50.6% of the variance in hierarchical models. Risk factors included being aged 4 to 5 years (OR = 2.650; p = 0.001), breastfeeding for 6 months or longer (OR = 2.172; p = 0.005), use of fluoride-free toothpaste (OR = 2.444; p = 0.004) and presence of hypomineralization of second primary molars (OR = 2.198; p = 0.005). Fluoridated water (OR = 0.239; p = 0.001) was a protective factor.</p><p><strong>Conclusion: </strong>While environmental factors play a significant role in the onset of dental caries, genetic factors may contribute to the development of the disease.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-11"},"PeriodicalIF":2.6,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145780249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Household Food Insecurity and Dental Caries Experience in Adolescents from Southern Brazil.","authors":"Danieli Londero da Silveira, Jessica Klöckner Knorst, Bruna Brondani, Mateus Zilch Scheuermann, Fabian Calixto Fraiz, Thiago Machado Ardenghi","doi":"10.1159/000549933","DOIUrl":"10.1159/000549933","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the study was to describe the association between household food insecurity and the prevalence of cavitated dental caries lesions in adolescents.</p><p><strong>Methods: </strong>This is a cross-sectional study nested within a 13-year cohort study that began in 2010 with a representative sample of preschool children aged 1-5 years from Santa Maria, southern Brazil. Participants were followed up in several phases of the cohort study, and this analysis used data from the most recent reevaluation, when individuals were aged between 14 and 18 years. Dental caries was assessed using the World Health Organization (WHO) criteria (cavitated caries lesions). Household food insecurity was measured using the Brazilian Food Insecurity Scale (EBIA), considering households with individuals under 18 years of age. The association between the presence of different levels of household food insecurity and caries experience was analyzed using adjusted Poisson regression models. Results are presented as mean ratios (MR) with 95% Confidence Intervals (95% CI).</p><p><strong>Results: </strong>Of the 406 adolescents assessed, 300 parents or guardians (73.9%) completed the food and nutrition insecurity questionnaire. Approximately 56.0% (95% CI: 50.2-61.7%) of households experienced some degree of food and nutrition insecurity. The prevalence of cavitated dental caries lesions was 38.0% (95% CI: 32.5-43.8%). Adolescents living in households with mild or moderate food insecurity had on average 62% higher mean surfaces with cavitated dental caries (MR 1.62; 95% CI: 1.28-2.06) than their counterparts without food insecurity. The presence of severe food insecurity was also associated with about twice the mean surface with cavitated dental caries (MR 1.92; 95% CI: 1.35-2.73).</p><p><strong>Conclusion: </strong>In addition to the nutritional consequences, food insecurity compromises oral health and should be a priority to reduce social inequalities in oral diseases.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-8"},"PeriodicalIF":2.6,"publicationDate":"2025-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145687205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on the Letter to the Editor Titled \"Modifying Diagnostic Terminology May Promote Evidence-Based Care\" by S.M.H. Nainar.","authors":"Vita Maciulskiene, Bente Nyvad, Fausto M Mendes","doi":"10.1159/000549772","DOIUrl":"10.1159/000549772","url":null,"abstract":"","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-2"},"PeriodicalIF":2.5,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145676310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Performance of an Intraoral Scanner for Caries Detection on Permanent Tooth Surfaces.","authors":"Anne-Marie Agius, Juliana No Cortes, Arthur R G Cortes, Nikolai J Attard, Gabriella Gatt","doi":"10.1159/000549789","DOIUrl":"10.1159/000549789","url":null,"abstract":"<p><strong>Introduction: </strong>Intraoral scanners with fluorescence technology (IOSFT) include a caries detection feature in addition to their standard scanning function. The aim of this study was to determine the diagnostic performance of the caries detection tool of the IOSFT Trios 4® on permanent premolar and molar surfaces when compared to visual and radiographic International Caries Detection and Assessment System (ICDAS).</p><p><strong>Methods: </strong>Participants (n = 71, age 6-88 years) were examined under standardised conditions using ICDAS criteria for visual caries detection of occlusal and smooth surfaces. Bitewing (BW) radiographs were used to examine proximal surfaces using ICDAS radiographic criteria. Finally, participants underwent an intraoral scan of both the maxilla and the mandible according to the manufacturer's instructions. The automated caries detection (ACD) output on the IOSFT software was compared to the visual ICDAS scores obtained clinically for occlusal and free smooth (buccal and lingual) surfaces; the IOSFT caries detection output was compared to radiographic ICDAS scores from BW radiographs for interproximal (mesial and distal) surfaces. Sensitivity, specificity, and accuracy values for each tooth surface were calculated.</p><p><strong>Results: </strong>Out of 3,684 permanent tooth surfaces examined, 461 surfaces with dental caries were included in the analysis. 392 were initial lesions (ICDAS 1-2), while 69 were moderate/severe (ICDAS 3-6). There was a moderate positive correlation (r = 0.4, p < 0.001) when comparing all ICDAS scores to IOSFT ACD categories for unrestored permanent occlusal surfaces. IOSFT ACD accuracy was higher for moderate/advanced lesions (ICDAS 3-6) lesions when compared to initial (ICDAS 1-2) ones (81% vs. 37.7%). For unrestored smooth surfaces, weak positive correlations were found when comparing all ICDAS scores to IOSFT ACD categories (r = 0.19, p < 0.001). Accuracy results for smooth surfaces were 93.5% for moderate/advanced and 77.1% for initial lesions. Correlations between BW ICDAS scores and IOSFT ACD scores for proximal surfaces were weak (r = 0.07, p = 0.019). Diagnostic accuracy was higher for moderate/advanced lesions when compared to initial ones (83.5% vs. 40.4%). There was a weak correlation between IOSFT ACD categories and ICDAS/visual categories for restored occlusal surfaces (r = 0.029, p = 0.68).</p><p><strong>Conclusion: </strong>IOSFT cannot currently replace visual and radiographic exams for caries detection.</p>","PeriodicalId":9620,"journal":{"name":"Caries Research","volume":" ","pages":"1-16"},"PeriodicalIF":2.6,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145676354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}