{"title":"Noise in clinical data: insights from assessment of aortic stenosis by echocardiography.","authors":"Joshua N Lloyd, Guy P Armstrong","doi":"10.1186/s12947-026-00372-8","DOIUrl":"10.1186/s12947-026-00372-8","url":null,"abstract":"","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"24 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13137482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xu Yanping, Yang Xiaojuan, Wu Jiali, Yang Xue, Pan Lu, Wang Xiaohong, Yang Ying, Wang Ying, Cao Wei, Na Lisha
{"title":"Quantitative assessment and prognostic value of myocardial work indices in sepsis-induced cardiomyopathy patients with left ventricular systolic dysfunction.","authors":"Xu Yanping, Yang Xiaojuan, Wu Jiali, Yang Xue, Pan Lu, Wang Xiaohong, Yang Ying, Wang Ying, Cao Wei, Na Lisha","doi":"10.1186/s12947-026-00370-w","DOIUrl":"10.1186/s12947-026-00370-w","url":null,"abstract":"","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"24 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ava R DeLonais-Parker, Spencer H Hobbs, Taylor R Coffman, Michael F Kanan, Yanqing Lyu, Elsa J Treiber, Rushda F Mansuri, Barbara C Okeke, Krista L Lentine, Mina M Benjamin
{"title":"Association of left atrial volume and function parameters with cardiovascular outcomes following kidney transplantation.","authors":"Ava R DeLonais-Parker, Spencer H Hobbs, Taylor R Coffman, Michael F Kanan, Yanqing Lyu, Elsa J Treiber, Rushda F Mansuri, Barbara C Okeke, Krista L Lentine, Mina M Benjamin","doi":"10.1186/s12947-026-00369-3","DOIUrl":"10.1186/s12947-026-00369-3","url":null,"abstract":"<p><strong>Purpose: </strong>Left atrial (LA) volume and strain parameters have been associated with cardiovascular outcomes in several cardiac pathologies, yet their role in predicting major adverse cardiovascular events (MACE) in kidney transplant (KT) recipients has not been explored.</p><p><strong>Methods: </strong>We retrospectively reviewed the records of adult KT recipients from our institution (2015-2024). We utilized baseline echocardiograms routinely acquired during KT workup to measure LA volumetrics and strain. MACE was the study's primary endpoint, defined as cardiovascular death, nonfatal myocardial infarction, stroke, major arrhythmias or heart failure hospitalization. Logistic regression, Kaplan-Meier and Cox proportional hazards regression were performed to evaluate the association between LA parameters and MACE.</p><p><strong>Results: </strong>Of 518 patients who underwent kidney transplant, 377 were in sinus rhythm with an acceptable quality echocardiogram (male, 56.7%; mean age 53.7 ± 13.1 years). Over a median follow up duration of 5.3 ± 2.3 years from KT, 82 patients reached the study endpoint. Kaplan-Meier analysis showed significantly lower MACE-free survival in patients with abnormal LA strain. After adjusting for confounding variables in the Cox Proportional Hazards model, of all LA parameters, lower LAScd (HR 0.94, 95% CI 0.89-0.98, p = 0.003), and LASr (HR 0.97, 95% CI 0.94-0.995, p = 0.02) were independently associated with MACE.</p><p><strong>Conclusion: </strong>In this retrospective single center study, LA strain parameters particularly LASr and LAScd were independently associated with MACE after KT. LA strain might have a role in risk stratification in this population.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"24 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12951988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147324716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian E Berg-Hansen, Rasmus Bach Sindre, Lisa M D Grymyr, Cecilie Linn Aas, Stig Urheim, Judy Hung, Dana Cramariuc
{"title":"Prognostic implications of impaired three-dimensional left atrial function and stiffness in primary mitral regurgitation.","authors":"Christian E Berg-Hansen, Rasmus Bach Sindre, Lisa M D Grymyr, Cecilie Linn Aas, Stig Urheim, Judy Hung, Dana Cramariuc","doi":"10.1186/s12947-026-00368-4","DOIUrl":"10.1186/s12947-026-00368-4","url":null,"abstract":"","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"24 1","pages":"6"},"PeriodicalIF":1.6,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12908262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146200037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new insight on imaging characteristics of pericoronary adipose tissue for cardiovascular risk.","authors":"Jiacheng Zhu, Dongxue Wu, Bo Han","doi":"10.1186/s12947-025-00362-2","DOIUrl":"10.1186/s12947-025-00362-2","url":null,"abstract":"","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"24 1","pages":"1"},"PeriodicalIF":1.6,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12862913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Murat Karaçam, Barkın Kültürsay, Azmican Kaya, Seda Tanyeri, Deniz Mutlu, Süleyman Çagan Efe, Çağdaş Bulus, Gülümser Sevgin Halil, Halit Eminoğlu, Kaan Kırali, Rezzan Deniz Acar
{"title":"Prognostic and functional value of left atrial indices in advanced heart failure.","authors":"Murat Karaçam, Barkın Kültürsay, Azmican Kaya, Seda Tanyeri, Deniz Mutlu, Süleyman Çagan Efe, Çağdaş Bulus, Gülümser Sevgin Halil, Halit Eminoğlu, Kaan Kırali, Rezzan Deniz Acar","doi":"10.1186/s12947-026-00366-6","DOIUrl":"10.1186/s12947-026-00366-6","url":null,"abstract":"","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"24 1","pages":"5"},"PeriodicalIF":1.6,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12825284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relationship between epicardial fat tissue, endothelial function, and coronary flow reserve in coronary microvascular disease patients.","authors":"Mengjiao Li, Yingying Huang, Linghui Bai, Wei Li, Chenbo Chu, Hui Liu","doi":"10.1186/s12947-025-00365-z","DOIUrl":"10.1186/s12947-025-00365-z","url":null,"abstract":"<p><strong>Background: </strong>Coronary microvascular disease (CMVD) is a major cause of hospitalization for a considerable number of patients with ischemia with non-obstructive coronary arteries (INOCA), with coronary flow reserve (CFR) reduction being the main feature of CMVD. However, imaging methods for CMVD evaluation are still lacking. This study aimed to investigate associations among epicardial fat thickness (EFT), endothelial function assessed by flow-mediated dilation (FMD), and CFR in patients with CMVD, and to evaluate their predictive value for CMVD diagnosis.</p><p><strong>Methods: </strong>CFR was measured by regadenoson stress echocardiography, while EFT and FMD were measured by transthoracic echocardiography and brachial artery vascular ultrasound in 66 subjects with INOCA. Multivariable logistic regression and receiver operating characteristic analysis were performed.</p><p><strong>Results: </strong>Twenty-nine patients were categorized into the CFR decreased group (CFR < 2.0), and thirty-seven patients were separated into the CFR normal group (CFR ≥ 2.0). EFT was significantly higher in the CFR decreased group (6.063 ± 1.732 mm vs. 5.95 ± 1.718 mm, P = 0.003), while FMD was significantly lower in the CFR decreased group [4.05 (3.10, 5.40) vs. 5.30 (4.85, 7.30), P = 0.011]. EFT was an independent predictor for CMVD [odds ratio: 5.084, 95% confidence interval: 1.498-17.251, P = 0.009]. A cut-off value of EFT > 5.51 mm predicted CMVD with 90% sensitivity and 71% specificity. FMD was not an independent predictor for CMVD, but when FMD < 4.65%, it predicted CMVD with 60% sensitivity and 83% specificity.</p><p><strong>Conclusions: </strong>EFT and FMD may serve as potential evaluation methods for CMVD in patients with INOCA. EFT was independently associated with the presence of CMVD in this cohort, offering significant clinical diagnostic insights. EFT is a novel independent predictor of CMVD in this specific population, while FMD provides complementary diagnostic value for risk stratification. These non-invasive markers may help to improve risk stratification in patients with microvascular dysfunction.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"24 1","pages":"2"},"PeriodicalIF":1.6,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12794452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Saad Al-Shammari, Ahmed Sermed Al Sakini, Mohammed Tarek Hasan, M Rafiqul Islam, Maryam Shahzad, Razan Adib Alsawadi, Shanmukh Sai Pavan Lingamsetty, Ahmed Ibrahim, Mohammed Dheyaa Marsool, Mohammed Elgebaly, Rohit Masih
{"title":"The predictive value of right ventricle speckle tracking echocardiography in patients undergoing cardiac surgery, a systematic review and meta-analysis.","authors":"Ali Saad Al-Shammari, Ahmed Sermed Al Sakini, Mohammed Tarek Hasan, M Rafiqul Islam, Maryam Shahzad, Razan Adib Alsawadi, Shanmukh Sai Pavan Lingamsetty, Ahmed Ibrahim, Mohammed Dheyaa Marsool, Mohammed Elgebaly, Rohit Masih","doi":"10.1186/s12947-025-00364-0","DOIUrl":"10.1186/s12947-025-00364-0","url":null,"abstract":"<p><strong>Background: </strong>Right ventricular (RV) dysfunction is a critical predictor of adverse outcomes in cardiac surgery patients. The assessment of right ventricular global longitudinal strain (GLS) echo has emerged as a promising tool for detecting early RV dysfunction. This meta-analysis evaluates the predictive value of RV GLS in these patients.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted. The primary outcomes included pooled diagnostic performance measures, including sensitivity, specificity, and the diagnostic odds ratio (DOR). A multiple-cutoff model was employed to determine the optimal RV-GLS threshold.</p><p><strong>Results: </strong>Ten observational studies involving 583 patients were included. RV-GLS demonstrated strong diagnostic accuracy, with a pooled area under the summary receiver operating characteristic curve (AUC) of 0.90 (95% CI: 0.82-1.00). The pooled DOR was 6.34 (95% CI: 3.20-12.57) with no heterogeneity (I² = 0%). Sensitivity was 0.79 (95% CI: 0.69-0.86; I² = 57.2%) and specificity was 0.78 (95% CI: 0.71-0.84; I² = 20.8%). The risk of publication bias was low (LFK index = 0.6). A multiple-threshold model identified - 15.25% as the optimal RV-GLS cutoff, achieving balanced sensitivity and specificity of 0.7423.</p><p><strong>Conclusions: </strong>RV-GLS demonstrates excellent predictive value for RV dysfunction in cardiac surgery patients.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"4"},"PeriodicalIF":1.6,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12822055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145780269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}