Canadian journal of ophthalmology. Journal canadien d'ophtalmologie最新文献

{"title":"Resident Perspectives 60–2","authors":"","doi":"10.1016/j.jcjo.2025.02.007","DOIUrl":"10.1016/j.jcjo.2025.02.007","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":"60 2","pages":"Pages e303-e306"},"PeriodicalIF":3.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143637800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitivity of ophthalmologists, residents, and optometrists in identifying peripheral retinal tears on ultra-widefield imaging.","authors":"Jesse J Jung, Xavier Chan, Kai Xiong Cheong, Yee Shan Dan, John Y Cheng, Eric W Lai, Huanye Li, Quan V Hoang","doi":"10.1016/j.jcjo.2025.02.002","DOIUrl":"10.1016/j.jcjo.2025.02.002","url":null,"abstract":"<p><strong>Objective: </strong>To compare the sensitivity of 3 groups of masked graders with varying levels of ophthalmic training to identify peripheral retinal breaks utilizing ultra-widefield orthogonal, directed peripheral steering, and auto-montaged images.</p><p><strong>Design: </strong>Retrospective observational cohort study.</p><p><strong>Participants: </strong>155 patients from a single vitreoretinal specialist's practice.</p><p><strong>Methods: </strong>221 eyes with pretreatment orthogonal, directed-peripheral steering, and auto-montage that underwent laser retinopexy for retinal tears between 2015 and 2021 were divided into 2 groups: treatment-naïve and control. Combined sensitivity and specificity of identifying all retinal breaks on orthogonal, directed-peripheral steering, and auto-montaged imaging were calculated compared with the gold standard of mydriatic, scleral depression examination. Linear probability modeling was performed to calculate the required surface area from auto-montage images to identify breaks that were missed initially on orthogonal images.</p><p><strong>Results: </strong>For orthogonal images, combined sensitivity was highest for ophthalmologists (67.53%), residents (62.34%), and then optometrists (55.84%). The sensitivity increased for orthogonal/steering (ophthalmologists [85.71%], residents [77.92%], and optometrists [67.53%]) and auto-montage (ophthalmologists [85.51%], residents (80.28%), and optometrists [75.00%]). To ensure identification of all tears with auto-montage that was initially missed on grading the orthogonal image, for every 10% increase in montage surface area, there was a 4.8 percentage point (%p) increase in the likelihood of detecting a retinal tear on montage image grading (p = 0.023).</p><p><strong>Conclusions: </strong>Masked graders had moderate sensitivity in identifying retinal breaks with ultra-widefield images. Even with directed-peripheral steering and auto-montage, optometrists had the lowest sensitivity compared to ophthalmology residents and general ophthalmologists and required increased surface area to identify all retinal breaks.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual outcomes of an extended depth of focus intraocular lens in patients with high ocular axial length.","authors":"James Wiens, Brad Hall","doi":"10.1016/j.jcjo.2025.01.019","DOIUrl":"10.1016/j.jcjo.2025.01.019","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the visual outcomes and quality of vision in patients receiving a nondiffractive extended depth of focus (EDOF) intraocular lens (IOL), when implanted in eyes with high ocular axial length (≥24.5 mm).</p><p><strong>Methods: </strong>This was a prospective, single-arm, single-surgeon study. Subjects were bilaterally implanted with the Vivity EDOF IOL (toric and nontoric). At 3 months postoperatively, assessments included binocular and monocular visual acuities at distance (6 m), intermediate (66 cm), and near (40 cm), manifest refraction, and administration of a visual disturbance questionnaire (QUVID) and a satisfaction questionnaire (IOLSAT).</p><p><strong>Results: </strong>At 3 months postoperatively, 100% (20/20), 100% (20/20), and 65% (13/20) of subjects had binocular visual acuity 20/32 or better at distance, intermediate, and near, respectively. Similar visual acuities were obtained with distance correction. At 3 months postoperatively, 93% of eyes (37/40) had manifest refraction spherical equivalent 0.5 D or less. Patient reported spectacle independence was 95% (19/20), 90% (18/20), and 40% (8/20) at distance, intermediate, and near, respectively. Patient-reported satisfaction with their corrected vision was 95% (19/20). In addition, 70% (14/20), 65% (13/20), and 70% (14/20) of subjects reported never or rarely experiencing starburst, halo, and glare, respectively.</p><p><strong>Conclusions: </strong>The results of this study suggest that the Vivity nontoric and toric IOLs can provide excellent distance and intermediate vision and functional near vision in eyes with high ocular axial length. Good spectacle independence can also be achieved at distance and intermediate, with high reported patient satisfaction and low reported visual disturbances.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual outcomes, quality of vision, and patient satisfaction of a trifocal intraocular lens.","authors":"Marius A Scheepers, Nina M Pasin, Brad Hall","doi":"10.1016/j.jcjo.2025.01.018","DOIUrl":"10.1016/j.jcjo.2025.01.018","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate visual outcomes, patient satisfaction, and quality of vision after bilateral Clareon PanOptix implantation.</p><p><strong>Methods: </strong>This was a prospective, observational, single-arm, single-surgeon, single-site study of the clinical outcomes following implantation of the Clareon PanOptix (toric and nontoric). A total of 28 subjects (56 eyes) completed the study. At 3 months postoperatively, assessments included binocular uncorrected and distance-corrected visual acuity at distance (UDVA, CDVA), intermediate (UIVA, DCIVA; 60 cm), and near (UNVA, DCNVA; 40 cm), refraction, and patient-reported outcomes on a satisfaction questionnaire (IOLSAT) and a visual disturbance questionnaire (QUVID).</p><p><strong>Results: </strong>Mean postoperative binocular CDVA, DCIVA, and DCNVA were -0.02 ± 0.09, 0.03 ± 0.11, 0.04 ± 0.07 logMAR, respectively. In addition, mean binocular UDVA, UIVA, and UNVA were 0.00 ± 0.09, 0.06 ± 0.11, 0.03 ± 0.06 logMAR, respectively. Mean postoperative manifest refraction spherical equivalent (MRSE) was 0.01 ± 0.23 D and 96% of eyes had MRSE of 0.5 D or less. The percentage of subjects reporting spectacle independence at distance, intermediate, and near was 100%, 100%, and 89%, respectively. Moreover, 89% of subjects rated their satisfaction as \"Satisfied\" or \"Very Satisfied.\" Additionally, 0%, 8%, and 7% of subjects were \"bothered quite a bit\" or \"bothered very much\" by starbursts, halos, and glare, respectively.</p><p><strong>Conclusions: </strong>Patients in this study who were implanted with the Clareon PanOptix intraocular lens had excellent refractive and visual outcomes and reported good spectacle independence at distance, intermediate, and near, high overall satisfaction, and low visual disturbances.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First reported autosomal recessive macular and cone dystrophy linked to homozygous PRPH2 variant in two Calabrian families.","authors":"Yi Zhai, Brian G Ballios","doi":"10.1016/j.jcjo.2025.02.003","DOIUrl":"10.1016/j.jcjo.2025.02.003","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optic nerve sheath fenestration for young patients with papilledema secondary to cerebral sinovenous thrombosis: a case series.","authors":"Lauren C Ditta, Asim F Choudhri, Andrew J Gienapp, Paul Klimo","doi":"10.1016/j.jcjo.2025.02.004","DOIUrl":"10.1016/j.jcjo.2025.02.004","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of 7 artificial intelligence-based intraocular lens power calculation formulas in medium-long eyes: 2-center study.","authors":"Wiktor Stopyra, Oleksiy Voytsekhivskyy, Andrzej Grzybowski","doi":"10.1016/j.jcjo.2025.01.020","DOIUrl":"10.1016/j.jcjo.2025.01.020","url":null,"abstract":"<p><strong>Objective: </strong>To compare accuracy of 7 artificial intelligence (AI)-based intraocular lens (IOL) power calculation formulas in medium-long eyes DESIGN: Retrospective observational study.</p><p><strong>Methods: </strong>The data of patients with eyes with an axial length of 24.5 mm to 25.99 mm, who underwent phacoemulsification between May 2018 and September 2023 were analyzed. Inclusion criteria were complete biometric and refractive data. Exclusion criteria were intraoperative or postoperative complications, previous eye surgery, or corneal diseases, postoperative best-corrected visual acuity less than 0.8 and corneal astigmatism greater than 2.0 D. Prior to cataract surgery, IOL power was calculated using a Zeiss IOLMaster 700 (Carl Zeiss Meditec AG, Jena, Germany). The power of the implanted IOL was randomly selected from the outcomes of one of the following formulas, i.e., SRK/T, Holladay 2, or Barrett Universal II. Three months after phacoemulsification, refraction was measured. Postsurgery, IOL power calculations were performed using the following formulas: Hill-RBF 3.0, Kane, PEARL-DGS, Ladas Super Formula AI (LSF AI), Hoffer QST, Karmona, and Nallasamy. The main outcome measures used were SD, since prediction error (PE) was zeroed, and the percentage of eyes with PE was within ±0.50 D.</p><p><strong>Results: </strong>One hundred eighty-four eyes with axial lengths of between 24.50 mm and 25.97 mm, were studied. The Karmona formula obtained the lowest SD (0.322) just before Hill-RBF 3.0 (0.324) and Pearl-DGS (0.334), however, without statistical significance (p > 0.05). The highest percentage of eyes with PE within ±0.50 D was achieved by Karmona (89.67%) ahead of Hill-RBF 3.0, LSF AI and Pearl-DGS (all equally 87.50 each) without statistical significance (p > 0.490).</p><p><strong>Conclusions: </strong>All studied AI-based formulas provided highly accurate outcomes in medium-long eyes.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"G-ROP versus WINROP for retinopathy of prematurity screening: a Calgary perspective.","authors":"Rahul Moorjani, Emi Sanders, Kyla Lavery, Ayman Abou Mehrem, Ravina Anand, Stephanie A Dotchin","doi":"10.1016/j.jcjo.2025.02.001","DOIUrl":"10.1016/j.jcjo.2025.02.001","url":null,"abstract":"<p><strong>Objective: </strong>Retinopathy of prematurity (ROP) remains one of the leading causes of childhood blindness. The current screening criteria in Canada have extremely high sensitivity but low specificity, leading to unnecessary examinations of neonates. Moreover, a screening algorithm that reduces the burden of screening is urgently needed owing to the increase in neonatal survival after extreme premature delivery, combined with the limited number of physicians qualified to screen for ROP. This retrospective study aimed to validate and compare the accuracy of the postnatal growth and ROP (G-ROP) and Weight, Insulin-like growth factor-1, Neonatal Retinopathy of Prematurity (WINROP) models for identifying neonates at risk for developing treatment-requiring ROP in a Canadian cohort.</p><p><strong>Design: </strong>Single-center retrospective cohort study conducted in Calgary, Alberta, Canada. Data from preterm infants born between 23- and 31-week gestational age or birth weight less than or equal to 1 250 grams were analyzed. A total of 1 001 infants were included in the study. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value for WINROP, and G-ROP algorithms were assessed in identifying neonates at risk of treatment-requiring ROP.</p><p><strong>Results: </strong>The WINROP algorithm yielded 95.7% sensitivity in identifying infants requiring ROP treatment compared to 100% sensitivity with the G-ROP model. Specificity for treatment-requiring ROP for WINROP was 41.7% and G-ROP was 30.4%.</p><p><strong>Conclusions: </strong>The G-ROP model was found to be more appropriate in our cohort, lending itself seamlessly to clinical care, while providing 100% sensitivity and greater specificity compared to current screening guidelines in our cohort.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of ginkgo biloba extract on macula and peripapillary perfusion examined using optical coherence tomography angiography.","authors":"Kevin Hodgson, Mathew M Palakkamanil, Angela Zhang, Oksana M Dyachok, Corey A Smith, Marcelo T Nicolela, Balwantray C Chauhan, Lesya M Shuba","doi":"10.1016/j.jcjo.2025.01.015","DOIUrl":"10.1016/j.jcjo.2025.01.015","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effect of ginkgo biloba extract (GBE) on optical coherence tomography angiography (OCT-A) macula and peripapillary perfusion parameters among patients with treated early-to-moderate primary open-angle glaucoma.</p><p><strong>Design: </strong>Clinical trial.</p><p><strong>Participants: </strong>Seventeen patients with early-to-moderate (≥10 dB MD) primary open-angle glaucoma were matched to 17 control patients based on age, sex, and glaucoma status. A total sample size of 34 was determined for effect size 0.5, alpha 0.05, power 0.81, and critical t = 2.03. Normality was confirmed using the Kolmogorov-Smirnov and Shapiro-Wilk tests.</p><p><strong>Methods: </strong>The intervention was 120 mg oral GBE twice daily for 4 months. OCT-A scans (15° × 15°) of the macula and peripapillary retina were acquired, two-dimensional projection slab images of the superficial vascular complex were exported, and image analysis was performed. Student's t test was used to compare perfusion density between groups, and between baseline and follow-up for each group. The main outcomes were perfusion density of the superficial vascular complex of the macula and the peripapillary region.</p><p><strong>Results: </strong>Comparison between baseline and 4 months' supplementation with GBE revealed no significant change in perfusion density in the macular area, 0.32 (0.04) versus 0.30 (0.04); p = 0.17, and was significantly lower in the peripapillary area, 0.44 (0.05) versus 0.42 (0.04); p = 0.02. No differences were observed in the control group.</p><p><strong>Conclusion: </strong>Four-month supplementation with GBE did not result in clinically significant improvement in macula or peripapillary perfusion density in patients with treated early-to-moderate primary open-angle glaucoma. Larger studies are needed to confirm an absence of neuroprotective effects of GBE.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicopathological comparison of benign eyelid tumours in tertiary care centers in Lima and Montreal from 2010 to 2019.","authors":"Katherine Jara, Emma Youhnovska, Emily Marcotte, Lelia Marroquín, Jorge Villalobos, Yuliana Alvarez, Asami Kawaguchi, Erick Urbano, Jose Velasco-Stoll, Pedro Muro, Christian El-Hadad, Bryan Arthurs, Miguel N Burnier","doi":"10.1016/j.jcjo.2025.01.008","DOIUrl":"10.1016/j.jcjo.2025.01.008","url":null,"abstract":"<p><strong>Objective: </strong>The eyelids are complex structures composed of various tissues. As such, a wide array of lesions exist that affect the eyelids. Clinical diagnosis of these lesions is essential to differentiate benign from malignant ones. Although accurate, some cases are misdiagnosed. Histopathology remains the crucial step in the final diagnosis of eyelid lesions. The objective of the study is to describe and compare the clinicopathological diagnosis of benign eyelid tumours between two tertiary care centers, one in South America and the other in North America, from 2010 to 2019.</p><p><strong>Methods: </strong>We reviewed 1 935 tumours at the McGill University Health Centre (MUHC)-McGill University Ocular Pathology and Translational Research Laboratory and 1 256 tumours collected at \"Dr. Jose Antonio Avendaño Valdez\" Ocular Pathology at the Instituto Nacional de Oftalmologia Peru (INO) (2010-2019). Demographic information and clinical and histopathological diagnoses were collected in an anonymized fashion.</p><p><strong>Results: </strong>The average age was 61.04 years at MUHC and 47.44 years at INO, benign tumours accounted for 78.11 % and 79.84%, respectively. The three most frequent benign tumour were squamous cell papilloma, nevus, and seborrheic keratosis at both sites. Lesions most commonly affected the upper and lower eyelid. 2.32% at the MUHC and 1.35% at the INO of cases were clinically misdiagnosed as benign tumours but confirmed malignant by histopathology.</p><p><strong>Conclusion: </strong>The most common lesions were squamous cell papilloma, nevus, and seborrheic keratosis, although the most common diagnosis varied, likely due to environmental factors differing at each site. Histopathology is essential for the accurate diagnosis of eyelid tumours.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}