Canadian journal of ophthalmology. Journal canadien d'ophtalmologie最新文献_第9页

Long-term outcomes of the Boston keratoprosthesis: a 15-year follow-up. 波士顿角膜假体的长期疗效：15年随访。

IF 2.8 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-09-01 DOI: 10.1016/j.jcjo.2025.08.005

Allison Bernstein, Youssef Gheth, Wissam Nassrallah, Moncef Berkache, Michel Haagdorens, Mona Harissi-Dagher

{"title":"Long-term outcomes of the Boston keratoprosthesis: a 15-year follow-up.","authors":"Allison Bernstein, Youssef Gheth, Wissam Nassrallah, Moncef Berkache, Michel Haagdorens, Mona Harissi-Dagher","doi":"10.1016/j.jcjo.2025.08.005","DOIUrl":"https://doi.org/10.1016/j.jcjo.2025.08.005","url":null,"abstract":"Objective: Boston keratoprosthesis (KPro) plays an important role in treating complex corneal disease but is associated with many complications. This study addresses correlations and trends found in KPro patients, to understand the evolution and optimize postoperative care to minimize complications.Design: A retrospective case series analyzing outcomes and evolution over 15 years.Participants: 157 eyes of 136 patients who underwent KPro surgery between 2008 and 2022 in Montreal, Quebec.Methods: Mean follow-up of 8.44 ± 4.70 years. Parameters followed included initial graft indication, age, pre-and-post-operative best corrected visual acuity (BCVA), intraocular pressure, cup-to-disc ratio, glaucoma interventions, and postoperative complications.Results: Aniridia was the most common initial graft indication. Fifty-four percent of patients had at least one prior graft failure. The most significant decrease in vision occurred in the first 3 years, followed by a gradual decrease, with 33% of patients retaining BCVA better than 20/200 by 15 years. The best BCVA was significantly better than the initial BCVA. Panocular conditions, such as aniridia, showed quicker visual decline than purely anterior segment pathologies. Retroprosthetic membranes, hypotony, and cystoid macular edema are common complications. Certain complications were seen to be significantly more prevalent in younger populations, although visual acuity and de novo glaucoma development did not differ significantly with age. De novo glaucoma occurred in 63.64%, diagnosed most frequently in the first 2-3 years, with one-third of patients requiring surgical intervention.Conclusions: KPro offers a prolongation of functional vision, but patients must be monitored closely to detect and treat associated complications, especially in the first 5 years postoperatively.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced monofocal versus conventional monofocal intraocular lenses: a systematic review and meta-analysis of randomized controlled trials. 增强型单焦点人工晶状体与传统单焦点人工晶状体：随机对照试验的系统回顾和荟萃分析。

IF 2.8 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-08-25 DOI: 10.1016/j.jcjo.2025.07.010

Nicholas Chieh Loh, Tulsi Kiran Pothakamuri, David Ziyou Chen

{"title":"Enhanced monofocal versus conventional monofocal intraocular lenses: a systematic review and meta-analysis of randomized controlled trials.","authors":"Nicholas Chieh Loh, Tulsi Kiran Pothakamuri, David Ziyou Chen","doi":"10.1016/j.jcjo.2025.07.010","DOIUrl":"https://doi.org/10.1016/j.jcjo.2025.07.010","url":null,"abstract":"Objective: To evaluate the comparative effectiveness of enhanced monofocal (EM) versus conventional monofocal (CM) intraocular lenses (IOLs) in senile cataract surgery, focusing on uncorrected intermediate visual acuity (UIVA) and secondary outcomes.Design: Systematic review and meta-analysis of randomized controlled trials (RCTs).Methods: A systematic literature search was conducted in PubMed, EMBASE, and Cochrane Library on March 8, 2024. RCTs comparing EM IOLs with CM IOLs in senile cataract surgery were included. The primary outcome was postoperative photopic binocular and monocular UIVA. Secondary outcomes included distance-corrected intermediate visual acuity (DCIVA), spectacle-free intermediate vision, binocular reading speed, postoperative visual phenomena, and patient-reported outcomes. The risk of bias was assessed using the Cochrane RoB 2 tool. The study was registered with the international Prospective Register of Systematic Reviews (CRD42024508318).Results: Six RCTs with 429 patients were included. EM IOLs (Tecnis Eyhance ICB00) were implanted in 422 eyes, and CM IOLs in 436 eyes. EM IOLs showed superior binocular UIVA (mean difference [MD]: -0.10 logMAR; 95% CI: -0.13 to -0.08) and monocular UIVA (MD: -0.09 logMAR; 95% CI: -0.11 to -0.06) compared to CM IOLs. EM IOLs also demonstrated superior binocular and monocular DCIVA. No broad significant differences were found between EM and CM IOLs in other secondary outcomes.Conclusions: EM IOLs offer a modest, but significant, improvement in UIVA and DCIVA compared to CM IOLs in senile cataract surgery, with a comparable safety profile. The evidence underscores the potential benefit of EM IOLs in enhancing intermediate vision, although generalizability is subject to the limitations of the included studies.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term prognosis of repeat Type I Boston keratoprosthesis. 重复I型波士顿角膜假体的远期预后。

IF 2.8 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-08-02 DOI: 10.1016/j.jcjo.2025.06.027

Wissam B Nassrallah, Emma Youhnovska, Mai Katbe, Andre Pollmann, Fady Sedarous, Rayan Tolba, Dominique Geoffrion, Mona Harissi-Dagher

{"title":"Long-term prognosis of repeat Type I Boston keratoprosthesis.","authors":"Wissam B Nassrallah, Emma Youhnovska, Mai Katbe, Andre Pollmann, Fady Sedarous, Rayan Tolba, Dominique Geoffrion, Mona Harissi-Dagher","doi":"10.1016/j.jcjo.2025.06.027","DOIUrl":"10.1016/j.jcjo.2025.06.027","url":null,"abstract":"Objective: The Boston Type I keratoprosthesis (B-KPro) is a synthetic corneal implant used to restore vision in cases of corneal blindness. While the B-KPro can achieve a visual acuity of better than 20/200, it is associated with a risk of implant failure. In cases of failure, a repeat B-KPro may offer another opportunity for vision restoration. This study aims to evaluate the long-term outcomes of patients undergoing repeat B-KPro after failure of the initial implant.Design: This is a retrospective cohort study.Participants: Eighteen patients who underwent two B-KPro implantations in the same eye, with a mean follow-up period of 8.1 ± 4.6 years.Methods: The primary endpoints were the failure rate of the implant and visual acuity at the last follow-up.Results: The failure rate of the repeat B-KPro (11.11% at 5 years) was significantly lower than that of the first B-KPro (88.89% at 5 years) (p < 0.0001) for the repeat cohort. Visual acuity better than 20/200 was achieved in 30.09% and 24.07% of patients at 3 years and 6 years, respectively, following repeat B-KPro, similar to outcomes observed after the first B-KPro. The incidence of phthisis was higher after the repeat B-KPro, but the rates of hypotony, endophthalmitis, corneal melt, and extrusion were lower compared to the first B-KPro.Conclusions: Repeat B-KPro can provide sustained visual acuity better than 20/200 after failure of the initial implant. Further studies with larger cohorts are needed to better understand the risks and benefits associated with repeat B-KPro.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Refractive and visual outcomes of macular edema of prematurity at 9 months, 2 years, and 5 years of age. 早产儿黄斑水肿在9个月、2岁和5岁时的屈光和视力结果。

IF 2.8 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-08-01 DOI: 10.1016/j.jcjo.2025.07.001

Jolan G Wu, Najma M Adan, Masis Ohan, Leona Ding, Alex T Legocki, Thomas B Gillette, Ayesha Shariff, Laura E Grant, Kristina Tarczy-Hornoch, Michelle T Cabrera

{"title":"Refractive and visual outcomes of macular edema of prematurity at 9 months, 2 years, and 5 years of age.","authors":"Jolan G Wu, Najma M Adan, Masis Ohan, Leona Ding, Alex T Legocki, Thomas B Gillette, Ayesha Shariff, Laura E Grant, Kristina Tarczy-Hornoch, Michelle T Cabrera","doi":"10.1016/j.jcjo.2025.07.001","DOIUrl":"10.1016/j.jcjo.2025.07.001","url":null,"abstract":"Objective: Determine visual and refractive outcomes of cystoid macular edema (CME) in preterm infants at risk for retinopathy of prematurity (ROP).Design: Prospective, observational cohort study.Participants: Premature infants eligible for ROP screening from 2 tertiary hospitals.Methods: Participants underwent awake handheld spectral domain optical coherence tomography (SD-OCT) imaging during their ROP exams. A single, masked pediatric ophthalmologist performed eye examinations, including cycloplegic streak retinoscopy, at 9 months, 2 years, and 5 years of age.Results: Among 94 preterm infants (175 eyes), birth weight was 1 018.09 ± 290.16 g and gestational age 28.38 ± 2.87 weeks. Thirty-two infants (34%) developed CME (mean maximum central foveal thickness 300 ± 350 µm) as newborns. No differences were found between those with versus those without CME in high myopia, mild myopia, mild hyperopia, and high hyperopia at 9 months (p = 1.00; n = 65), 2 years (p = 1.00; n = 47), and 5 years (p = 1.00; n = 31). Mean spherical equivalents (1.89 ± 2.19 vs 1.73 ± 1.15, 1.77 ± 1.92 vs 0.99 ± 1.48, and 1.28 ± 0.74 vs 0.41 ± 1.59 at 9 months, 2 years, and 5 years, respectively; p = 0.87-1.00), visual acuity (p = 0.14-1.00), astigmatism (p = 0.71-1.00), and strabismus (p = 1.00) also did not correlate with a history of CME at any time point.Conclusions: We identified no associations between CME in premature newborns screened for ROP and visual acuity or refractive error at 9 months, 2 years, or 5 years of age.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flieringa scleral fixation ring-assisted Descemet membrane endothelial keratoplasty in complex eyes. 巩膜固定环辅助下角膜内皮移植术在复杂眼中的应用。

IF 2.8 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-07-31 DOI: 10.1016/j.jcjo.2025.07.003

Gabriele Gallo Afflitto, Shafi Balal, Francesco Aiello, Vincenzo Maurino

引用次数: 0

Choroidal features on widefield optical coherence tomography angiography in eyes with circumscribed choroidal hemangioma. 宽视场光学相干断层血管造影眼底限定脉络膜血管瘤的脉络膜特征。

IF 2.8 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-07-31 DOI: 10.1016/j.jcjo.2025.07.002

Judith E Kreminger, Reinhard Told, Stephanie Rokitansky, Adrian Reumueller, Roman Dunavoelgyi, Stefan Sacu

{"title":"Choroidal features on widefield optical coherence tomography angiography in eyes with circumscribed choroidal hemangioma.","authors":"Judith E Kreminger, Reinhard Told, Stephanie Rokitansky, Adrian Reumueller, Roman Dunavoelgyi, Stefan Sacu","doi":"10.1016/j.jcjo.2025.07.002","DOIUrl":"10.1016/j.jcjo.2025.07.002","url":null,"abstract":"Objective: To evaluate choroidal morphologic and vascular findings in eyes with circumscribed choroidal hemangioma (CCH) in a 21 mm × 26 mm widefield (WF) OCT-Angiography (OCTA; VG200D: Intalight Inc., San Jose, CA).Methods: Consecutive patients with CCH were included in this prospective, observational study at the Department of Ophthalmology and Optometry, Medical University of Vienna, Austria. Imaging consisted of ultrasonography and WF-OCTA. Choroidal vascularity index (CVI) and choroidal thickness (CT) were assessed in study eyes (SE) and fellow eyes (FE) using the software of the device. Measurement of CT and CVI excluded the area of CCH and an equivalent area of FE.Results: Nineteen patients (female: n = 9 (47.4%), mean age: 61 ± 11 years) were included in the study. In ultrasonography, the mean largest basal diameter and thickness were 7.32 ± 2.12 mm and 2.81 ± 0.75 mm, respectively. CT was statistically significantly higher in SE, as compared to FE (294.6 ± 74.2 µm vs 239.9 ± 46.8 µm; paired t test p < 0.001), while CVI was statistically significantly lower in SE, as compared to FE (0.44 ± 0.05 vs 0.45 ± 0.05; paired t test: p = 0.012). Intraretinal or subretinal fluid had no statistically significant influence on CT (with fluid: 303.0 ± 84.3 µm vs without fluid: 285.3 ± 65.0 µm; t test: p = 0.619) and CVI (with fluid: 0.42 ± 0.05 vs without fluid: 0.45 ± 0.03; t test: p = 0.185).Conclusions: Intraretinal or subretinal fluid had no impact on CT and CVI of SE. CT is higher and CVI is lower in SE as compared to FE, when excluding the area of CCH in SE and an equivalent area in FE. This suggests that the choroid plays a crucial role in the disease mechanism of CCH.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of developing thyroid eye disease in patients with thyroid dysfunction that received a COVID-19 vaccination. 接种COVID-19疫苗的甲状腺功能障碍患者患甲状腺眼病的风险

IF 2.8 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-07-30 DOI: 10.1016/j.jcjo.2025.06.017

Linus Amarikwa, Patcharaporn Chandraparnik, Karen M Wai, Ehsan Rahimy, Benyam Kinde, Euna Koo, Chase Ludwig, Chrysoula Dosiou, Prithvi Mruthyunjaya, Andrea L Kossler

{"title":"Risk of developing thyroid eye disease in patients with thyroid dysfunction that received a COVID-19 vaccination.","authors":"Linus Amarikwa, Patcharaporn Chandraparnik, Karen M Wai, Ehsan Rahimy, Benyam Kinde, Euna Koo, Chase Ludwig, Chrysoula Dosiou, Prithvi Mruthyunjaya, Andrea L Kossler","doi":"10.1016/j.jcjo.2025.06.017","DOIUrl":"10.1016/j.jcjo.2025.06.017","url":null,"abstract":"Objective: To assess the risk of developing thyroid eye disease (TED) after mRNA COVID-19 vaccination in patients with thyroid dysfunction.Design: A retrospective cohort study.Participants: All patients with hyperthyroidism with no history of TED prior to March 2021 and no history of another orbital inflammatory disease.Methods: The rates of TED in patients that received or did not receive any type of COVID-19 vaccination were compared. TED incidence was also compared in those receiving influenza and Tdap vaccines. All patient records were identified using the TriNetX network (Cambridge, MA). Propensity score matching (PSM) was done to control for differences in baseline demographics and medical comorbidities. The primary outcome was the relative risk of developing TED after COVID-19 vaccination.Results: A total of 373,909 patients with hyperthyroidism and no signs of TED were identified. After matching and assessing for vaccination status, 69,378 patients were in the COVID-19 vaccine and no COVID-19 vaccine cohorts. We found that COVID-19 vaccination resulted in an increased risk of developing TED when compared with the no COVID-19 vaccine (RR = 1.49, 95% CI: 1.39-1.58), Tdap (RR = 1.80, 95% CI: 1.56-2.06), and influenza cohorts (RR = 1.68, 95% CI: 1.49-1.88).Conclusions: Patients with underlying hyperthyroidism demonstrated an increased risk of developing TED following COVID-19 vaccination. Although further studies are required to confirm these findings, patients with underlying autoimmune thyroid dysfunction should receive education on the signs and symptoms of TED and be monitored for the development of TED after COVID-19 vaccination.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biomarkers of microvascular retinal perfusion in OCTA indicative of coronary heart disease. OCTA显示冠心病的微血管视网膜灌注生物标志物。

IF 2.8 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-07-29 DOI: 10.1016/j.jcjo.2025.06.022

Maximilian Pawloff, Natasa Jeremic, Azin Zarghami, Matthias Hasun, Andreas Pollreisz, Marlene Hollaus, Markus Ritter, Irene Steiner, Ursula Schmidt-Erfurth

{"title":"Biomarkers of microvascular retinal perfusion in OCTA indicative of coronary heart disease.","authors":"Maximilian Pawloff, Natasa Jeremic, Azin Zarghami, Matthias Hasun, Andreas Pollreisz, Marlene Hollaus, Markus Ritter, Irene Steiner, Ursula Schmidt-Erfurth","doi":"10.1016/j.jcjo.2025.06.022","DOIUrl":"10.1016/j.jcjo.2025.06.022","url":null,"abstract":"Objective: To assess changes in retinal perfusion and microvascular architecture associated with coronary artery stenosis (CAS) due to coronary heart disease (CHD) and establish optical coherence tomography angiography (OCTA) as a noninvasive screening tool for CHD.Methods: In this cross-sectional exploratory study, 982 eyes of 512 patients that underwent coronary angiography due to suspected CHD were included. All patients underwent OCTA to quantify perfusion density (PD) and fractal dimension (FD) within the superficial and deep vascular plexus in 1 mm, 3 mm, and 6 mm rings placed over the macula and optic nerve head (ONH).Results: The study investigated the association between maximal stenosis and retinal microvascular parameters in 512 patients. In the superficial retinal plexus, significant negative associations were found between cardiac stenosis and retinal perfusion density (PD) (p = 0.0091) and fractal dimension (FD) (p = 0.0014) in the inner ring. Similar associations were observed in the deep plexus (PD: p = 0.047; FD: p = 0.013). In the outer ring, mean PD and FD were lower in the left compared to the right eye (PD, superficial: p < 0.0001, deep: p < 0.0001; FD, superficial: p < 0.0001, deep: p = 0.0012). However, no significant associations were found in the optic nerve head. Overall, the study suggests that retinal microvascular parameters may serve as indicators of stenosis presence, especially in specific retinal regions and layers, providing insights into potential noninvasive methods for cardiovascular risk assessment.Conclusions: Retinal microvasculature parameters, such as PD and FD, may serve as indicators of CAS. Retinal imaging with OCTA might offer a noninvasive screening modality for cardiovascular risk assessment.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utility of optical coherence tomography in anticipation of visual outcomes in endophthalmitis. 光学相干断层扫描在眼内炎视力预后预测中的应用。

IF 2.8 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-07-29 DOI: 10.1016/j.jcjo.2025.06.025

Sloane McTavish, Sandra Hoyek, Marisa Tieger, Elizabeth Rossin, David Wu, James Harris, Nimesh A Patel

{"title":"Utility of optical coherence tomography in anticipation of visual outcomes in endophthalmitis.","authors":"Sloane McTavish, Sandra Hoyek, Marisa Tieger, Elizabeth Rossin, David Wu, James Harris, Nimesh A Patel","doi":"10.1016/j.jcjo.2025.06.025","DOIUrl":"10.1016/j.jcjo.2025.06.025","url":null,"abstract":"Objective: To investigate whether specific findings on optical coherence tomography (OCT) in patients with endophthalmitis are correlated with visual prognosis.Design: A single-center, retrospective, consecutive series.Participants: Patients with endophthalmitis at Massachusetts Eye and Ear (2011-2021) who underwent spectral-domain OCT imaging were included.Methods: OCT images were assessed over time, as well as their association with final best-corrected visual acuity.Results: Out of the 429 eyes of 419 patients included, 232 eyes of 222 patients had available OCT data. The most common OCT finding was epiretinal membrane, with its incidence increasing over time and peaking at 6 months, after accounting for any media opacity that might obscure an underlying ERM. Mean central macular thickness and foveal thickness were lower in patients with good vision compared with patients with vision <20/100 at final follow-up (p = 0.023 and p < 0.001, respectively). Intraretinal fluid was more frequent in exogenous endophthalmitis (p = 0.038), whereas vitritis was more prevalent in endogenous endophthalmitis (p = 0.004). Absence of view and presence of subretinal fluid on OCT were associated with worse visual outcomes.Conclusions: Endophthalmitis leads to varying pathology on optical coherence tomography based on the exogenous or endogenous subtype. Epiretinal membrane formation is the most common and increases over time. Certain findings, such as subretinal fluid, increased central macula thickness, and absence of view portend a worse visual outcome.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144682101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alexia without agraphia secondary to glioblastoma multiforme. 多形性胶质母细胞瘤继发的失读症，无书写障碍。

IF 2.8 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-07-28 DOI: 10.1016/j.jcjo.2025.06.009

Rui Tang, Rhys Ishihara, Pamela Davila Siliezar, Noor A Laylani, Peter Mortensen, Andrew G Lee

引用次数: 0