Canadian journal of ophthalmology. Journal canadien d'ophtalmologie最新文献

{"title":"Long-term effects of drusenoid pigment epithelial detachment on the retina and the choroid.","authors":"Marlene Hollaus, Magdalena Baratsits, Irene Steiner, Günther Weigert, Maximilian Pawloff, Georgios Mylonas, Ursula Schmidt-Erfurth, Stefan Sacu","doi":"10.1016/j.jcjo.2025.06.010","DOIUrl":"10.1016/j.jcjo.2025.06.010","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the long-term effects of drusenoid pigment epithelial detachment (DPED) on the overlying inner and outer retinal layers and the underlying choroid.</p><p><strong>Methods: </strong>Forty-two eyes from 33 patients with DPED due to intermediate age-related macular degeneration were included in this prospective observational cohort study, which was conducted from December 2017 until July 2023. Patients underwent spectral-domain optical coherence tomography every 6 months. Evaluated parameters included maximum DPED height (=DPED apex) and location of the DPED apex at baseline; furthermore, DPED height, retinal thickness (RT), visibility of retinal layers, presence of hyperreflective foci (HRF), choroidal thickness (CT), and best-corrected visual acuity (BCVA) at baseline and each follow-up visit, as well as development of macular neovascularization or geographic atrophy.</p><p><strong>Results: </strong>DPED height, RT, and CT did not change significantly during the observation period (all p values > 0.05). DPED height and RT correlated significantly regardless of visit (estimate = -0.36, 95% CI = -0.4 to -0.32; p < 0.0001), DPED height, and CT did not (p > 0.05). Outer retina (estimate = -2.19, 95% Cl = -2.74 to -1.63; p < 0.0001), location in the central millimeter (estimate = -0.79, 95% Cl = -1.31 to -0.27; p = 0.004), and the presence of HRF (estimate = -0.65, 95% Cl = -1.05 to -0.24; p = 0.003) were significantly associated with retinal layer visibility regardless of visit, while DPED height was not (p > 0.05). BCVA was not significantly associated with DPED height, RT, CT, or the number of visible outer and inner retinal layers regardless of visit (all p values > 0.05).</p><p><strong>Conclusions: </strong>Our results indicate that increasing DPED height may significantly reduce the thickness of the overlying retina but not of the underlying choroid. Fewer outer retinal layers were visible compared to the inner retina at the DPED apex. Location in the central millimeter of the macula and presence of HRF also reduced the number of visible retinal layers. Impairment of the retinal morphology, which seems to be more pronounced in the outer than the inner retina, need not be accompanied by functional impairment and can recover in case of DPED regression.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suprachoroidal viscopexy for chronic rhegmatogenous retinal detachment repair with inferior breaks.","authors":"Rajeev H Muni, Isabela Martins Melo, John Park, Aurora Pecaku","doi":"10.1016/j.jcjo.2025.05.024","DOIUrl":"10.1016/j.jcjo.2025.05.024","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of subperiosteal orbital abscess in pediatric population: a comparative study.","authors":"Muhammad Abumanhal, Igal Leibovitch, Dana Niry, Nemer Sayed Ahmad, Daphna Mezad-Koursh, Anat Bachar Zipori, Avraham Abergel, Ran Ben Cnaan","doi":"10.1016/j.jcjo.2025.06.004","DOIUrl":"10.1016/j.jcjo.2025.06.004","url":null,"abstract":"<p><strong>Objective: </strong>To assess clinical and radiological parameters as predictive factors for surgical intervention in children diagnosed with subperiosteal orbital abscess (SPOA).</p><p><strong>Methods: </strong>A retrospective study conducted over 8 years (2016-2023) at a tertiary medical center. A total of 624 children with periorbital/orbital cellulitis were assessed for eligibility. Orbital imaging was performed on 107 children, and 45 were diagnosed with SPOA and included for this study. Patients diagnosed with SPOA were divided into two groups: conservative treatment (n = 20) and surgical intervention (n = 25). Clinical and laboratory parameters were evaluated. Radiological parameters, including abscess volume, abscess dimensions, and proptosis, were measured using three-dimensional imaging techniques.</p><p><strong>Results: </strong>Age, fever, leukocyte count, and C-reactive protein levels did not significantly differ between the surgical and conservative groups. However, neutrophils to lymphocytes ratio (NLR) was significantly higher in the surgical group (8.1 vs 3.64; p < 0.001). Radiological findings showed that both absolute radiological proptosis (19 mm vs 16.1 mm; p < 0.001), and the difference in proptosis between the affected and fellow eyes (4 mm vs 2.1 mm; p < 0.001) were significantly greater in the surgical group. A relative abscess volume ≥0.11 mL was found to predict the need for surgery with a sensitivity of 88% and specificity of 85%. Anteroposterior and craniocaudal dimensions of the abscess were significantly larger in the surgical group.</p><p><strong>Conclusion: </strong>NLR and radiological parameters, particularly proptosis and abscess volume, are valuable predictors of surgical intervention in children with SPOA. These findings suggest that combining clinical and radiological assessments can improve decision making for treating pediatric orbital infections, potentially guiding timely surgical management.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the performance of Microsoft Copilot, GPT-4 and Google Gemini in ophthalmology","authors":"","doi":"10.1016/j.jcjo.2025.06.015","DOIUrl":"10.1016/j.jcjo.2025.06.015","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":"60 4","pages":"Page e619"},"PeriodicalIF":3.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144614850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of assistive devices in improving reading performance in vision rehabilitation patients.","authors":"Farhad Ghaseminejad, Karen Eden, Wilma M Hopman, Mark Bona","doi":"10.1016/j.jcjo.2025.06.008","DOIUrl":"10.1016/j.jcjo.2025.06.008","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effectiveness of assistive devices in improving the reading performance of patients in a vision rehabilitation clinic.</p><p><strong>Methods: </strong>This is a prospective observational cohort study of patients referred to a hospital-based, urban, vision rehabilitation clinic in Southeastern Ontario. Patient demographics, ophthalmic diagnoses, and reading performance were investigated. Median reading speeds in words per minute (wpm) were compared with and without assistive devices, using the Minnesota Reading tool (MNRead). The relationships between improvement in reading speed and MNRead components (i.e., reading acuity, critical print size, and reading accessibility index), visual acuity, age, level of education, and previous exposure to vision rehabilitation were assessed. Subgroup analyses of patients diagnosed with age-related macular degeneration (AMD) and glaucoma were carried out.</p><p><strong>Results: </strong>A total of 199 patients were included in this study, with 71.9% over the age of 65. Most self-identified as female (68.8%) and Caucasian (93.0%). The median improvement in reading speed with assistive devices was 39.5 wpm (P < 0.001). Improvement in reading speeds was positively correlated with visual acuity (P = 0.005) and inversely correlated with patients' age (P = 0.029). Patients with glaucoma experienced a more substantial increase in reading speed (66.2 wpm) with assistive devices compared to AMD (38.0 wpm). Handheld magnifiers were significantly more effective in AMD patients, as compared to glaucoma.</p><p><strong>Conclusions: </strong>This study provides an overview of a group of patients accessing vision rehabilitation interventions. We use the MNRead-based reading speed assessment to demonstrate the varying effectiveness of assistive devices across different patient groups.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"F. Y. EYE","authors":"","doi":"10.1016/j.jcjo.2025.06.014","DOIUrl":"10.1016/j.jcjo.2025.06.014","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":"60 4","pages":"Page 260"},"PeriodicalIF":3.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144614726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative use of PreserFlo MicroShunt for managing post-XEN avascular bleb in Posner-Schlossman Syndrome.","authors":"Javier García-Bardera, Julián García-Feijoo, Laura Morales-Fernández, José María Martínez-de-la-Casa","doi":"10.1016/j.jcjo.2025.06.006","DOIUrl":"10.1016/j.jcjo.2025.06.006","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood banks saving sight: collaboration for successful treatment of ligneous conjunctivitis.","authors":"Eileen Javidi, Simon Javidi, Patrick Hamel, Melissa Girard, Marc Germain, Marie-Claude Robert","doi":"10.1016/j.jcjo.2025.06.013","DOIUrl":"10.1016/j.jcjo.2025.06.013","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to report the presentation and outcomes of three cases of ligneous conjunctivitis (LC) treated successfully with topical plasminogen concentrate (TPC).</p><p><strong>Design: </strong>Aggregate results of three n-of-1 clinical trials.</p><p><strong>Participants: </strong>Three patients from a tertiary pediatric health care center with a recent diagnosis of LC due to plasminogen deficiency.</p><p><strong>Methods: </strong>Three patients with LC and low serum plasminogen activity were enrolled in n = 1 clinical trials. Patients received hourly TPC eye drops in the affected eye, tapered per treatment response to once daily.</p><p><strong>Results: </strong>The first patient presented with Streptococcus pyogenes corneal ulcer and pseudomembranes (PMs) in his right eye following an upper respiratory tract infection. Despite aggressive topical antibiotics and subsequent addition of topical corticosteroids, corneal perforation occurred. Urgent penetrating keratoplasty, peeling of the PMs, and amniotic membrane transplantation were performed to both upper and lower palpebral conjunctivas. PMs recurred rapidly, prompting further investigation and the diagnosis of LC. The patient was started on hourly TPC and improved promptly, with complete resolution of PMs after 4 weeks. The second and third patients were started on the TPC protocol shortly after presentation. They showed resolution of PMs after 3 weeks and 1 week, respectively. Two patients were stable under maintenance TPC once daily at last follow-up with no recurrences. One patient had PM recurrence with upper respiratory tract infections, requiring intermittent increases of TPC to hourly dosage.</p><p><strong>Conclusions: </strong>Despite regulatory barriers, TPC yielded highly favorable outcomes in these challenging cases of LC.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relapse of B-cell acute lymphoblastic leukemia revealed by multiple ocular locations.","authors":"Lauriana Solecki, Anne Sophie Gauthier, Arnaud Sauer","doi":"10.1016/j.jcjo.2025.06.012","DOIUrl":"https://doi.org/10.1016/j.jcjo.2025.06.012","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative predictors of success of iStent placement with cataract surgery.","authors":"Gurkaran S Sarohia, Christopher J Rudnisky","doi":"10.1016/j.jcjo.2025.06.007","DOIUrl":"10.1016/j.jcjo.2025.06.007","url":null,"abstract":"<p><strong>Objective: </strong>To investigate and assess the intraoperative predictors for successful 1-year outcomes of iStent inject for patients with open angle glaucoma.</p><p><strong>Design: </strong>Retrospective case series.</p><p><strong>Participants: </strong>Patients who underwent combined iStent inject placement and cataract surgery between October 2018 and August 2022.</p><p><strong>Methods: </strong>A priori predictors of interest included the number of stents placed, the number of clicks required to place them, stent spacing, intraoperative reflux of blood from the stent, and observed flow of aqueous through external vasculature. The primary outcome was the intraocular pressure (IOP) medication index.</p><p><strong>Results: </strong>This study included 99 eyes of 57 patients. The mean preoperative IOP was 14.9 (±3.7) mm Hg, and mean number of drops were 1.7 (±0.7). The mean postoperative follow-up was 15.6 (±5.9) months. The mean postoperative IOP was 13.6 (±6.1) mm Hg and medication reduction was -1.5 (±4.2 mm Hg). Using the IOP medication index, 92.6% of eyes were categorized as having a successful procedure. Multivariate analysis showed that flow in both one (p = 0.030) and two (p = 0.034) stents were independent predictors of success after 1 year.</p><p><strong>Conclusions: </strong>The IOP medication index showed a statistically significant association between flow from both 1 and 2 stents. Flow can be used as a predictor by surgeons to change patients' surgical plans intraoperatively and to monitor patients more closely postoperatively.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}