Gabriela G Lee, Erick Rivera-Grana, Zelia M Correa, Maura Di Nicola
{"title":"Sympathetic ophthalmia in a patient with ciliary body melanoma and extraocular extension.","authors":"Gabriela G Lee, Erick Rivera-Grana, Zelia M Correa, Maura Di Nicola","doi":"10.1016/j.jcjo.2024.11.009","DOIUrl":"https://doi.org/10.1016/j.jcjo.2024.11.009","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justin Muste, Obinna Ugwuegbu, Param Bhatter, Delaney Ryan, James Bena, Shirley Wu, Molly Snider, Andrew P Schachat, Rishi P Singh, Jeffrey Goshe
{"title":"Inpatient topical glaucoma medication-ordering discrepancies: a study of frequency and risk factors for inaccurate reconciliation.","authors":"Justin Muste, Obinna Ugwuegbu, Param Bhatter, Delaney Ryan, James Bena, Shirley Wu, Molly Snider, Andrew P Schachat, Rishi P Singh, Jeffrey Goshe","doi":"10.1016/j.jcjo.2024.11.006","DOIUrl":"https://doi.org/10.1016/j.jcjo.2024.11.006","url":null,"abstract":"<p><strong>Objective: </strong>To describe the frequency of topical glaucoma medication-ordering discrepancies (MOD) during transitions of care and to explore factors that may be associated with an increased risk of MOD.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Participants: </strong>A random sample of adult patients with primary open-angle glaucoma (POAG) on at least 1 topical glaucoma medication admitted to any Cleveland Clinic facility between January 1, 2012, to January 1, 2023. Study patients must have had at least 1 visit with a Cole Eye Institute ophthalmologist-who diagnosed POAG and prescribed one or more topical glaucoma medications-within 12 months prior to admission.</p><p><strong>Methods: </strong>Charts were manually reviewed for discrepant prescriptions. Logistic regressions were employed to assess potential risk factors.</p><p><strong>Results: </strong>MOD was noted in 288 of 944 (30.5%) encounters. Patient demographics, hospital site, provider type, admitting service, and pharmacy verification did not alter the odds of MOD. Patients on 3 medications experienced MOD most frequently (41.2%) followed by 1 medication (29.3%) and then 2 medications (26.8%) (P = 0.032). Omission was the most common MOD type across all reconciliations followed by substitution, addition, and wrong eye MOD (23.8%, 9.1%, 3.3%, and 0.53%, respectively). Medication discrepancy in a previous hospitalization increased the odds of discrepancy in the next (OR 5.1, 95% CI [3.2-8.4]; P < 0.001). A discrepancy on admission significantly increased MOD rates at transfer and discharge (P < 0.001).</p><p><strong>Conclusions: </strong>Glaucoma MOD occurred in approximately one-third of the inpatient encounters in this study, suggesting incongruence at transitions of care. Patients with inpatient MOD were significantly more likely to have an MOD in subsequent admissions.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kiko Zi Yi Huang, Graham E Trope, Yvonne M Buys, Ya-Ping Jin
{"title":"Unequal access to routine eye exams in Canada: an analysis of government-funded eye exam coverage policy and associated vision health outcomes.","authors":"Kiko Zi Yi Huang, Graham E Trope, Yvonne M Buys, Ya-Ping Jin","doi":"10.1016/j.jcjo.2024.11.008","DOIUrl":"https://doi.org/10.1016/j.jcjo.2024.11.008","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Balas, Alexander J Kaplan, Kaisra Esmail, Solin Saleh, Rahul A Sharma, Peng Yan, Parnian Arjmand
{"title":"Translating ophthalmic medical jargon with artificial intelligence: a comparative comprehension study.","authors":"Michael Balas, Alexander J Kaplan, Kaisra Esmail, Solin Saleh, Rahul A Sharma, Peng Yan, Parnian Arjmand","doi":"10.1016/j.jcjo.2024.11.003","DOIUrl":"https://doi.org/10.1016/j.jcjo.2024.11.003","url":null,"abstract":"<p><strong>Objective: </strong>Our goal was to evaluate the efficacy of OpenAI's ChatGPT-4.0 large language model (LLM) in translating technical ophthalmology terminology into more comprehensible language for allied health care professionals and compare it with other LLMs.</p><p><strong>Design: </strong>Observational cross-sectional study.</p><p><strong>Participants: </strong>Five ophthalmologists each contributed three clinical encounter notes, totaling 15 reports for analysis.</p><p><strong>Methods: </strong>Notes were translated into more comprehensible language using ChatGPT-4.0, ChatGPT-4o, Claude 3 Sonnet, and Google Gemini. Ten family physicians, masked to whether the note was original or translated by ChatGPT-4.0, independently evaluated both sets using Likert scales to assess comprehension and utility for clinical decision-making. Readability was evaluated using Flesch Reading Ease and Flesch-Kincaid Grade Level scores. Five ophthalmologist raters compared performance between LLMs and identified translation errors.</p><p><strong>Results: </strong>ChatGPT-4.0 translations significantly outperformed the original notes in terms of comprehension (mean score of 4.7/5.0 vs 3.7/5.0; p < 0.001) and perceived usefulness (mean score of 4.6/5.0 vs 3.8/5.0; p < 0.005). Readability analysis demonstrated mildly increased linguistic complexity in the translated notes. ChatGPT-4.0 was preferred in 8 of 15 cases, ChatGPT-4o in 4, Gemini in 3, and Claude 3 Sonnet in 0 cases. All models exhibited some translation errors, but ChatGPT-4o and ChatGPT-4.0 had fewer inaccuracies.</p><p><strong>Conclusions: </strong>ChatGPT-4.0 can significantly enhance the comprehensibility of ophthalmic notes, facilitating better interprofessional communication and suggesting a promising role for LLMs in medical translation. However, the results also underscore the need for ongoing refinement and careful implementation of such technologies. Further research is needed to validate these findings across a broader range of specialties and languages.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salvatore Parrulli, Matteo Airaldi, Valentina Folegani, Stefano Erba, Andrea Govetto, Federico Zicarelli, Alessandro Invernizzi, Giovanni Staurenghi, Matteo G Cereda
{"title":"Multimodal imaging features of retinal neovascularization in response to 3 anti-VEGF injections.","authors":"Salvatore Parrulli, Matteo Airaldi, Valentina Folegani, Stefano Erba, Andrea Govetto, Federico Zicarelli, Alessandro Invernizzi, Giovanni Staurenghi, Matteo G Cereda","doi":"10.1016/j.jcjo.2024.11.001","DOIUrl":"10.1016/j.jcjo.2024.11.001","url":null,"abstract":"<p><strong>Objective: </strong>To analyze longitudinal changes of retinal neovessels (NV) in eyes with proliferative diabetic retinopathy (PDR) after 3 monthly intravitreal injections (IVI) of ranibizumab by means of different imaging modalities, particularly focusing on optical coherence tomography (OCT) and OCT-angiography (OCT-A) features.</p><p><strong>Methods: </strong>Prospective, monocentric study, Luigi Sacco Hospital, Milan. Consecutive patients with PDR were enrolled. All patients underwent color fundus photography (CFP), fluorescein angiography (FA), SD-OCT, and OCT-A at baseline (t0) and after 3 monthly IVI of ranibizumab (t1). Neovessels (NVs) were classified as flat, elevated, flat-elevated, or table-top using OCT scans and further analyzed on FIJI. Qualitative and quantitative NV characteristics were evaluated. Vessel density (VD) was calculated as the mean of all the white pixels of the NV and expressed as a percentage of the area of the NV (VD = NV area × 100).</p><p><strong>Results: </strong>Thirty-six NVs in 10 patients were studied. The regression of NVs at t1 was partial in 66.7% of cases and complete in 33.3%. Table-top NV demonstrated more frequently a complete regression (P = .03). A significant reduction of the NV area, perimeter, and VD was observed at t1 (P < .001). NVs that showed a complete regression had higher mean VD values at t0 compared with NVs, which showed a partial regression (P = .02). Flat NVs had more frequently a complete vitreous attachment, while table-top showed more often a partial vitreous detachment with focal NV adhesion (P < .05). A complete regression was more often observed for NVs with a partial vitreous detachment and focal NV adhesion at t0 (10/12), while most of the NVs with a complete vitreous attachment showed a partial regression (18/24) (P < .001).</p><p><strong>Conclusions: </strong>The table-top configuration of the neovessel, higher VD values at baseline, and the presence of a focal adhesion of the vitreous over the NV were factors associated with a higher risk of complete regression of the NV in response to 3 monthly IVI of ranibizumab.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}