Canadian journal of ophthalmology. Journal canadien d'ophtalmologie最新文献_第10页

Anatomic and visual outcomes of pars plana vitrectomy in patients with incomplete closure of Zone 3 scleral lacerations.

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-01-31 DOI: 10.1016/j.jcjo.2025.01.010

Sami H Uwaydat, Muhammad Z Chauhan, Pedro S Tetelbom

引用次数: 0

Improvement of stereopsis following strabismus surgery in adults: a retrospective analysis. 成人斜视手术后立体视功能的改善：回顾性分析。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-01-31 DOI: 10.1016/j.jcjo.2024.12.007

Oded Rock, Tiran Golani, Sari David, Mor Vered, Rasha Mosleh, Sharon Armarnik, Tamara Wygnanski-Jaffe

{"title":"Improvement of stereopsis following strabismus surgery in adults: a retrospective analysis.","authors":"Oded Rock, Tiran Golani, Sari David, Mor Vered, Rasha Mosleh, Sharon Armarnik, Tamara Wygnanski-Jaffe","doi":"10.1016/j.jcjo.2024.12.007","DOIUrl":"10.1016/j.jcjo.2024.12.007","url":null,"abstract":"Objective: Adults who undergo strabismus surgery, in addition to cosmesis, could benefit from improved stereopsis. This improvement is associated with the performance of motor skill tasks in young adults; they reduce the risk of tripping or falling during everyday locomotion and improve reading efficiency. This study aimed to assess stereopsis level after strabismus surgery in adults who underwent strabismus surgery for any reason.Methods: Retrospective observational study of adult patients who underwent strabismus surgery at our institution between 2010 and 2022.Results: One hundred and thirty-two patients were included. Postoperatively, 48% had a stereo acuity better than 100 seconds of arc, and only 21.5% had no stereopsis. The most significant factor influencing improved stereopsis after surgery was the angle of strabismus postoperatively (p = 0.018). There was a statistically significant correlation between fusion at a distance and the stereo acuity (p = 0.0337). There was no statistically significant correlation between the stereo acuity level and the strabismus angle of deviation, the strabismus direction (vertical, horizontal, or combined), or the type (esotropia or exotropia) before or after the surgery. Although not statistically significant (p = 0.6579), the underlying cause categories were correlated with the stereo level. Patients with neurological causes demonstrated higher levels of stereopsis, followed by TED, whereas patients with childhood strabismus have the lowest probability of regaining stereopsis after surgery.Conclusions: Although long-standing strabismus reduces the potential for binocularity, surgery may be beneficial and improve stereopsis regardless of the cause of strabismus.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pterygium-like conjunctival nevus: a clinicopathological study.

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-01-30 DOI: 10.1016/j.jcjo.2025.01.009

Satoru Kase, Kiriko Hirooka, Emi Takakuwa, Susumu Ishida

引用次数: 0

A case of VEXAS syndrome with therapy refractive macular involvement. 屈光性黄斑受累治疗的VEXAS综合征1例。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-01-15 DOI: 10.1016/j.jcjo.2025.01.002

Raphael Lechtenboehmer, Matthias M Mauschitz, Frank G Holz, Robert P Finger, Maximilian W M Wintergerst

引用次数: 0

"Blindness" is not a contraindication for voretigene neparvovec-rzyl treatment: a review of 9 cases. “失明”不是voretigene neparvovec-rzyl治疗的禁忌症——对9例病例的回顾。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-01-15 DOI: 10.1016/j.jcjo.2024.12.013

Deepika C Parameswarappa, Kirk A J Stephenson, Mark Seamone, Cynthia X Qian, Rajeev H Muni, Peter J Kertes, Ajoy Vincent, Elise Héon

{"title":"\"Blindness\" is not a contraindication for voretigene neparvovec-rzyl treatment: a review of 9 cases.","authors":"Deepika C Parameswarappa, Kirk A J Stephenson, Mark Seamone, Cynthia X Qian, Rajeev H Muni, Peter J Kertes, Ajoy Vincent, Elise Héon","doi":"10.1016/j.jcjo.2024.12.013","DOIUrl":"10.1016/j.jcjo.2024.12.013","url":null,"abstract":"Objective: Biallelic RPE65 pathogenic variants may cause Leber congenital amaurosis (LCA). Voretigene neparvovec-rzyl (VN, Luxturna) is the only approved subretinal gene therapy that demonstrated benefit and safety. The eligibility criteria are vague and variable between centres. This is the first comprehensive outcome report of RPE65-LCA patients with World Health Organization blindness criteria vision treated with VN.Design: Multicentre retrospective case series.Participants: Patients meeting the treatment criteria for VN who had best-corrected visual acuity (BCVA) <20/400 or visual field (VF)III4e isopter <10°.Methods: Patients were followed for a mean of 11.1 ± 4.7 months. Age, sex, BCVA, central retinal thickness (CRT), retinal atrophy, VF, full-field stimulus testing (FST), and subjective impressions were assessed.Results: Nine patients met the inclusion criteria (mean: BCVA 1.89 LogMAR, range: 1.4 - 2.7 LogMAR, mean age: 28.7-years-old, range: 17-59 years). Though VF area did not improve, FST improved in patients with better baseline FST (-8.83 dB vs -0.56 dB; p = 0.010), and better VFV4e (7245 vs 341o2; p < 0.001) and III4e (596.1 vs 24.8o2; p = 0.011) area. VA improved in younger (20 vs 32 years; p = 0.011) patients with thinner CRT1mm (155 vs 193 µm; p = 0.038). VFV4e loss occurred in older (38 vs 19 years; p = 0.001) patients with worse baseline V4e area (1728 vs 8159o2; p < 0.001). Subjective improvement in dim light navigation skills occurred in younger patients (20.3 vs 45.3 years; p < 0.001).Conclusions: Blindness is not a contraindication to VN treatment for RPE65-LCA. Superior results correlated with greater baseline FST but not with CRT1mm, provided that measurable outer retinal structures persist.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A national benchmarking survey for quality improvement and safety in ophthalmology 眼科质量改进与安全的国家基准调查。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-01-14 DOI: 10.1016/j.jcjo.2024.11.013

Michael T. Kryshtalskyj , Jeremy Rau , Emi Sanders , Helen Chung , Andrew C. Crichton , Chryssa McAlister , Alex M Ragan

引用次数: 0

Twenty four-hour intraocular pressure fluctuation in treated glaucoma patients: a pilot study. 青光眼治疗患者24小时眼压波动：一项初步研究

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-01-14 DOI: 10.1016/j.jcjo.2024.11.010

Sunil Ruparelia, Rodolfo Bonatti, Jeremy A Murphy, Marcelo T Nicolela, Brennan D Eadie, Balwantray C Chauhan, Oksana M Dyachok, Lesya M Shuba

{"title":"Twenty four-hour intraocular pressure fluctuation in treated glaucoma patients: a pilot study.","authors":"Sunil Ruparelia, Rodolfo Bonatti, Jeremy A Murphy, Marcelo T Nicolela, Brennan D Eadie, Balwantray C Chauhan, Oksana M Dyachok, Lesya M Shuba","doi":"10.1016/j.jcjo.2024.11.010","DOIUrl":"10.1016/j.jcjo.2024.11.010","url":null,"abstract":"Objective: To conduct a pilot study to evaluate and compare the 24-hour habitual intraocular pressure (IOP) and ocular perfusion pressure (OPP) fluctuation in glaucoma patients treated with medical therapy, selective laser trabeculoplasty (SLT) or trabeculectomy.Design: Pilot study.Participants: Criteria for inclusion were patients aged 18 years or older with well-controlled IOP with either maximum tolerated medical therapy, previous SLT, or previous trabeculectomy.Methods: Recruited patients were admitted to the sleep lab for 24-hour serial habitual IOP and blood pressure measurements. IOP and OPP fluctuation among the 3 treatment groups were compared.Results: Thirty three (33) eyes from 33 patients were recruited in this study, including 11 patients in the medical therapy group, 11 patients in the SLT group, and 11 patients in the trabeculectomy group. The medical therapy group was found to have significantly higher 24-hour IOP fluctuation (8.3 ± 1.6 mmHg) than the SLT (3.5 ± 1.9 mmHg) and trabeculectomy (4.3 ± 1.3 mmHg) groups (P < 0.001). Mean 24-hour OPP fluctuation was also significantly higher in the medical therapy group (18.5 ± 4.0 mmHg) than the SLT (11.9 ± 7.3 mmHg) and trabeculectomy (14.1 ± 3.9 mmHg) groups (P < 0.05). No difference in IOP or OPP fluctuation was found between SLT and trabeculectomy groups (P > 0.05).Conclusions: Both SLT and trabeculectomy may be more effective in reducing 24-hour IOP and OPP fluctuation than medical therapy alone. IOP and OPP fluctuation was comparable between SLT and trabeculectomy cohorts. Future studies are warranted to investigate this further.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142884983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-organism fungal keratitis in a novel keratoprosthesis device. 新型角膜假体装置中的双生物真菌性角膜炎。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-01-14 DOI: 10.1016/j.jcjo.2024.11.014

Mobin Abdi, Erica Darian-Smith, Gilad Litvin, David S Rootman, Clara C Chan

引用次数: 0

Bilateral corneal perforation secondary to immunotherapy for metastatic melanoma. 转移性黑色素瘤免疫治疗继发双侧角膜穿孔1例。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-01-14 DOI: 10.1016/j.jcjo.2024.11.011

Prem A H Nichani, Alonso Gutierrez Guerinoni, David S Rootman, Clara C Chan

引用次数: 0

Subsequent intraocular lens surgery in eyes with combined versus sequential phacovitrectomy. 联合晶状体切除术与序贯晶状体切除术在眼内的后续人工晶状体手术。

IF 3.3 4区医学

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-01-14 DOI: 10.1016/j.jcjo.2024.11.012

Fatma F Shakarchi, Ahmed F Shakarchi, Mohamed K Soliman, Abdallah A Ellabban, Ahmed B Sallam

{"title":"Subsequent intraocular lens surgery in eyes with combined versus sequential phacovitrectomy.","authors":"Fatma F Shakarchi, Ahmed F Shakarchi, Mohamed K Soliman, Abdallah A Ellabban, Ahmed B Sallam","doi":"10.1016/j.jcjo.2024.11.012","DOIUrl":"10.1016/j.jcjo.2024.11.012","url":null,"abstract":"Objective: To determine the risk factors for subsequent intraocular lens (IOL) surgery among eyes undergoing either combined or sequential phacovitrectomy.Design: Retrospective cohort study.Participants: Adult patients undergoing phacoemulsification at 8 United Kingdom National Health Service clinical centers between July 2003 and March 2015. Patients undergoing surgery for a dropped nucleus fragment, glaucoma, or iris problems were excluded.Methods: The eyes were categorized into 3 groups: with previous vitrectomy, undergoing combined phacovitrectomy, and with both previous vitrectomy and current combined phacovitrectomy. These groups were compared based on preoperative ocular and systemic factors, intraoperative findings, and the subsequent need for a second IOL surgery. The Poisson model was used to calculate adjusted relative risks (aRR).Results: 5,215 eyes were included: 2,124 with previous vitrectomy, 2,512 with combined phacovitrectomy, and 579 eyes with previous vitrectomy and currently combined phacovitrectomy. The risk of subsequent IOL surgery was 0.6% (reference group) in eyes with previous vitrectomy, 1.6% (aRR 2.6, CI: 1.4-5.1) in eyes with current combined phacovitrectomy, and 3.3% (aRR 3.8, CI: 1.7-8.3) in eyes with previous plus current combined phacovitrectomy. Other significant risk factors were age (aRR 0.98/year), pseudoexfoliation (aRR 6.76, CI: 2-28), zonular dialysis (aRR 10.6, CI: 4.8-24), scleral buckle in the current surgery (aRR 8.05, CI: 4-14), and the use of silicone oil (aRR 3.6, CI: 1.6-8.4) compared to no tamponade.Conclusions: Combined phacovitrectomy was associated with a higher risk of IOL complications than sequential surgery. This information is useful for planning surgery in patients requiring both cataract and retinal surgeries.","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142892249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0