Choroidal features on widefield optical coherence tomography angiography in eyes with circumscribed choroidal hemangioma.

IF 2.8 4区医学 Q1 OPHTHALMOLOGY

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Pub Date : 2025-07-31 DOI:10.1016/j.jcjo.2025.07.002

Judith E Kreminger, Reinhard Told, Stephanie Rokitansky, Adrian Reumueller, Roman Dunavoelgyi, Stefan Sacu

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引用次数: 0

Abstract

Objective: To evaluate choroidal morphologic and vascular findings in eyes with circumscribed choroidal hemangioma (CCH) in a 21 mm × 26 mm widefield (WF) OCT-Angiography (OCTA; VG200D: Intalight Inc., San Jose, CA).

Methods: Consecutive patients with CCH were included in this prospective, observational study at the Department of Ophthalmology and Optometry, Medical University of Vienna, Austria. Imaging consisted of ultrasonography and WF-OCTA. Choroidal vascularity index (CVI) and choroidal thickness (CT) were assessed in study eyes (SE) and fellow eyes (FE) using the software of the device. Measurement of CT and CVI excluded the area of CCH and an equivalent area of FE.

Results: Nineteen patients (female: n = 9 (47.4%), mean age: 61 ± 11 years) were included in the study. In ultrasonography, the mean largest basal diameter and thickness were 7.32 ± 2.12 mm and 2.81 ± 0.75 mm, respectively. CT was statistically significantly higher in SE, as compared to FE (294.6 ± 74.2 µm vs 239.9 ± 46.8 µm; paired t test p < 0.001), while CVI was statistically significantly lower in SE, as compared to FE (0.44 ± 0.05 vs 0.45 ± 0.05; paired t test: p = 0.012). Intraretinal or subretinal fluid had no statistically significant influence on CT (with fluid: 303.0 ± 84.3 µm vs without fluid: 285.3 ± 65.0 µm; t test: p = 0.619) and CVI (with fluid: 0.42 ± 0.05 vs without fluid: 0.45 ± 0.03; t test: p = 0.185).

Conclusions: Intraretinal or subretinal fluid had no impact on CT and CVI of SE. CT is higher and CVI is lower in SE as compared to FE, when excluding the area of CCH in SE and an equivalent area in FE. This suggests that the choroid plays a crucial role in the disease mechanism of CCH.

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宽视场光学相干断层血管造影眼底限定脉络膜血管瘤的脉络膜特征。

目的：评价21 mm × 26 mm宽视场（WF） oct -血管造影(OCTA；VG200D: Intalight Inc., San Jose， CA)。方法：连续的CCH患者被纳入奥地利维也纳医科大学眼视光学学系的前瞻性观察性研究。影像学包括超声、WF-OCTA。使用该设备软件对研究眼（SE）和伴眼（FE）的脉络膜血管指数（CVI）和脉络膜厚度（CT）进行评估。CT和CVI的测量排除了CCH的面积和等效的FE面积。结果：共纳入19例患者（女性：n = 9(47.4%)，平均年龄61±11岁）。超声检查显示，平均最大基底直径为7.32±2.12 mm，厚度为2.81±0.75 mm。SE组CT评分高于FE组（294.6±74.2µm vs 239.9±46.8µm）；配对t检验p < 0.001)， SE组CVI低于FE组(0.44±0.05 vs 0.45±0.05；配对t检验：p = 0.012)。视网膜内或视网膜下积液对CT的影响无统计学意义(积液：303.0±84.3µm vs无积液：285.3±65.0µm；t检验：p = 0.619)和CVI(有液：0.42±0.05 vs无液：0.45±0.03；T检验：p = 0.185)。结论：视网膜下液和视网膜下液对SE的CT和CVI无影响。当排除SE中的CCH面积和FE中的等效面积时，SE中的CT高于FE， CVI低于FE。这表明脉络膜在CCH的发病机制中起着至关重要的作用。

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来源期刊

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 医学-眼科学

CiteScore

3.20

自引率

4.80%

发文量

223

审稿时长

38 days

期刊介绍： Official journal of the Canadian Ophthalmological Society. The Canadian Journal of Ophthalmology (CJO) is the official journal of the Canadian Ophthalmological Society and is committed to timely publication of original, peer-reviewed ophthalmology and vision science articles.