Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz最新文献

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Gesundheitliche Beurteilung von Materialien und Gegenständen für den Lebensmittelkontakt im Rahmen des Lebensmittel- und Futtermittelgesetzbuches : 228. Mitteilung. 根据《食品和饲料法》对与食品接触有关的材料和物品进行健康评估:228。.说明
IF 1.7 4区 医学
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Pub Date : 2025-07-01 DOI: 10.1007/s00103-025-04072-y
{"title":"Gesundheitliche Beurteilung von Materialien und Gegenständen für den Lebensmittelkontakt im Rahmen des Lebensmittel- und Futtermittelgesetzbuches : 228. Mitteilung.","authors":"","doi":"10.1007/s00103-025-04072-y","DOIUrl":"https://doi.org/10.1007/s00103-025-04072-y","url":null,"abstract":"","PeriodicalId":9562,"journal":{"name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","volume":"68 7","pages":"838-842"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Implementation research-effective implementation of evidence-based interventions into practice]. [实施研究——将循证干预措施有效地落实到实践中]。
IF 1.7 4区 医学
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Pub Date : 2025-07-01 Epub Date: 2025-07-04 DOI: 10.1007/s00103-025-04088-4
Charbel El Bcheraoui, Johanna Hanefeld, Lars Schaade
{"title":"[Implementation research-effective implementation of evidence-based interventions into practice].","authors":"Charbel El Bcheraoui, Johanna Hanefeld, Lars Schaade","doi":"10.1007/s00103-025-04088-4","DOIUrl":"10.1007/s00103-025-04088-4","url":null,"abstract":"","PeriodicalId":9562,"journal":{"name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","volume":"68 7","pages":"715-717"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum zu: Impfen: Prävention von Infektionskrankheiten und ihren Folgen. 疫苗:预防传染病及其后果。
IF 1.7 4区 医学
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Pub Date : 2025-07-01 DOI: 10.1007/s00103-025-04058-w
Maren Mylius, Joseph Kuhn
{"title":"Erratum zu: Impfen: Prävention von Infektionskrankheiten und ihren Folgen.","authors":"Maren Mylius, Joseph Kuhn","doi":"10.1007/s00103-025-04058-w","DOIUrl":"10.1007/s00103-025-04058-w","url":null,"abstract":"","PeriodicalId":9562,"journal":{"name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","volume":" ","pages":"827"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Piloting an electronic death certificate (eTB app)-physicians' user experiences]. [试行电子死亡证明(eTB应用程序)-医生的用户体验]。
IF 1.7 4区 医学
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Pub Date : 2025-07-01 Epub Date: 2025-06-02 DOI: 10.1007/s00103-025-04082-w
Sebastian Brunner, Michaela Hesse, Diana Borucki, Ulrich Vogel, Martin Mücke, Gülay Ateş
{"title":"[Piloting an electronic death certificate (eTB app)-physicians' user experiences].","authors":"Sebastian Brunner, Michaela Hesse, Diana Borucki, Ulrich Vogel, Martin Mücke, Gülay Ateş","doi":"10.1007/s00103-025-04082-w","DOIUrl":"10.1007/s00103-025-04082-w","url":null,"abstract":"<p><strong>Background: </strong>Funded by the Federal Ministry of Health, the Federal Institute for Drugs and Medical Devices, in cooperation with the Federal Statistical Office, developed an electronic death certificate app and tested it in two federal states to assess its user-friendliness and acceptance. Death certificates are filled out by hand and pass through various offices for transcription and coding before cause of death statistics are published. The certificates are often incorrect and difficult to read. In Germany, there are 16 different forms depending on the federal state, and none of them meet World Health Organization (WHO) requirements for international comparability.</p><p><strong>Methods: </strong>A mixed-methods approach was used with validated questionnaires and semi-structured guided interviews (February to September 2023). The quantitative data were analysed descriptively with SPSS and the qualitative data were analysed using content analysis with MAXQDA.</p><p><strong>Results: </strong>In two federal states, a total of 89 out of 201 physicians completed the surveys and a further 11 were interviewed. Almost all respondents (n = 70) have a positive attitude towards digitalisation in healthcare (94%), see a benefit in processes and organisation (93%) and have no concerns about data security (73%). The majority confirmed the user-friendliness of the eTB app. The qualitative data highlighted that plausibility checking, error prevention and improved readability were convincing arguments in favour of the eTB app.</p><p><strong>Conclusion: </strong>The eTB app is easy to use and useful. In particular, the fast data transfer makes the eTB app an important milestone in digitalization. Improvements are required for use in practice.</p>","PeriodicalId":9562,"journal":{"name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","volume":" ","pages":"818-826"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leveraging research steering committees for stakeholder engagement: a multifaceted strategy in Brazilian implementation projects. 利用研究指导委员会促进利益相关者参与:巴西实施项目的多方面战略。
IF 1.7 4区 医学
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Pub Date : 2025-07-01 Epub Date: 2025-05-31 DOI: 10.1007/s00103-025-04081-x
Carlos Alberto Dos Santos Treichel, Maria Giovana Borges Saidel, Ana Laura Salomé Lourencetti, Maria Fernanda Lirani Dos Reis, Angela Pereira Figueiredo, Bianca Brandão da Silva, Rosana Teresa Onocko Campos
{"title":"Leveraging research steering committees for stakeholder engagement: a multifaceted strategy in Brazilian implementation projects.","authors":"Carlos Alberto Dos Santos Treichel, Maria Giovana Borges Saidel, Ana Laura Salomé Lourencetti, Maria Fernanda Lirani Dos Reis, Angela Pereira Figueiredo, Bianca Brandão da Silva, Rosana Teresa Onocko Campos","doi":"10.1007/s00103-025-04081-x","DOIUrl":"10.1007/s00103-025-04081-x","url":null,"abstract":"<p><strong>Introduction: </strong>Research steering committees (RSCs) are increasingly recognized as a strategy for stakeholder engagement. Drawing on the experiences of participants from three RSCs involved in health care implementation projects in Brazil, this study aims to examine the contributions of RSCs to implementation research based on their impact on implementation outcomes.</p><p><strong>Methods: </strong>This descriptive, exploratory, qualitative study was conducted between August and December 2024. Shared appreciation groups with eight researchers facilitated consensus on RSC operationalization. Additionally, semistructured interviews with 12 RSC members from three research projects explored the contributions to stakeholder engagement and implementation outcomes. Data were analyzed using thematic content analysis.</p><p><strong>Results: </strong>Thirteen discrete implementation strategies were identified within four categories: use evaluative and iterative strategies, adapt and tailor to context, develop stakeholder interrelationships, and train and educate stakeholders. The RSCs influenced six implementation outcomes: acceptability, adoption, appropriateness, feasibility, penetration, and sustainability. Appropriateness and feasibility emerged as the most prominent outcomes.</p><p><strong>Conclusion: </strong>Research steering committees constitute a multifaceted implementation strategy that fosters structured stakeholder engagement. By integrating multiple implementation strategies, they enhance collaboration, contextual adaptation, and shared governance. Their impact on appropriateness and feasibility highlights their relevance as a support mechanism for implementation success and sustainability.</p>","PeriodicalId":9562,"journal":{"name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","volume":" ","pages":"747-757"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging community-engaged research and implementation science methods to advance public health practice. 连接社区参与的研究和实施科学方法,以促进公共卫生实践。
IF 1.7 4区 医学
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Pub Date : 2025-07-01 Epub Date: 2025-06-05 DOI: 10.1007/s00103-025-04079-5
Margaret A Handley, Lucía Abascal Miguel, Lisa Marie Thompson, Jennifer Velloza
{"title":"Bridging community-engaged research and implementation science methods to advance public health practice.","authors":"Margaret A Handley, Lucía Abascal Miguel, Lisa Marie Thompson, Jennifer Velloza","doi":"10.1007/s00103-025-04079-5","DOIUrl":"10.1007/s00103-025-04079-5","url":null,"abstract":"<p><p>Addressing public health challenges through equitable, evidence-based strategies remains a pressing global need. Implementation science bridges research and practice, offering methods to improve intervention design, delivery, and evaluation. Concurrently, community-engaged research embeds equity and trust into public health initiatives. This paper introduces selected community engagement methods and related implementation science approaches to address characteristic common constraints in public health practice, illustrated with real-world examples. Adapting the Knowledge to Action framework, we present a discussion of community-engaged methods and accompanying case studies. The discussion follows four phases present in applied public health research: (1) identifying and defining the problem, (2) designing and modifying the intervention, (3) evaluating the intervention, and (4) communicating and disseminating findings. For each phase, we highlight common barriers, recommend methods, and present case studies such as rapid qualitative methods, human-centered design, and participatory data analysis. Case studies demonstrate these methods' effectiveness in addressing common constraints. These approaches ensured that interventions were culturally tailored, contextually relevant, and evidence-based.</p>","PeriodicalId":9562,"journal":{"name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","volume":" ","pages":"797-808"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing noncommunicable public health programs: A system dynamics approach to understanding reach, maintenance, and implementation costs. 加强非传染性公共卫生规划:了解覆盖范围、维护和实施成本的系统动力学方法。
IF 1.7 4区 医学
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Pub Date : 2025-07-01 Epub Date: 2025-05-30 DOI: 10.1007/s00103-025-04069-7
Simon Keith Chiu, Alix Hall, Louise Freebairn
{"title":"Enhancing noncommunicable public health programs: A system dynamics approach to understanding reach, maintenance, and implementation costs.","authors":"Simon Keith Chiu, Alix Hall, Louise Freebairn","doi":"10.1007/s00103-025-04069-7","DOIUrl":"10.1007/s00103-025-04069-7","url":null,"abstract":"<p><strong>Introduction: </strong>Noncommunicable diseases (NCDs) cause an estimated 41 million deaths globally each year, with cardiovascular diseases, cancers, chronic respiratory diseases, and diabetes being the leading contributors. Modifiable risk factors elevate the risk of NCDs. Despite the availability of effective prevention programs, their consistent implementation remains limited, highlighting the need for strategies to improve delivery and reduce costs. The reach, efficacy, adoption, implementation, and maintenance (RE-AIM) framework and system modelling can help in understanding and improvement of the implementation and maintenance of public health initiatives.</p><p><strong>Methods: </strong>This research used a system dynamics model to explore hypothetical pathways between reach, maintenance, and the cost-related components of implementation within the RE-AIM framework. Scenarios explored the influence of strategies for enhancing reach and maintenance and the resulting impact on participation and cost.</p><p><strong>Results: </strong>Scenarios that considered alternative pathways to engagement (i.e. enhanced reach strategies) and re-engagement led to higher participation rates by utilising alternative pathways and reducing dependence on initial reach. However, this increased overall program costs due to the population cycling between engagement and disengagement.</p><p><strong>Conclusion: </strong>This modelling study highlights the complex non-linear relationships that affect the implementation of public health prevention, emphasising the need for support strategies to maintain engagement. The study shows that while alternative pathways to reach can improve participation, disengagement remains a significant challenge, impacting overall costs. Sustainment strategies that are both effective and cost-efficient are crucial for maintaining engagement and enhancing the effectiveness of public health programs.</p>","PeriodicalId":9562,"journal":{"name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","volume":" ","pages":"769-777"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tackling schistosomiasis in fisherfolk communities in Uganda: Enablers and challenges for implementing paediatric schistosomiasis mass drug administration from the perspective of district health authorities. 乌干达渔民社区的血吸虫病防治:从地区卫生当局的角度实施儿科血吸虫病大规模药物管理的推动因素和挑战。
IF 1.7 4区 医学
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Pub Date : 2025-07-01 Epub Date: 2025-06-06 DOI: 10.1007/s00103-025-04066-w
Lisa Sophie Reigl, Isabelle L Lange, Orkan Okan, Stella Neema, Andrea S Winkler
{"title":"Tackling schistosomiasis in fisherfolk communities in Uganda: Enablers and challenges for implementing paediatric schistosomiasis mass drug administration from the perspective of district health authorities.","authors":"Lisa Sophie Reigl, Isabelle L Lange, Orkan Okan, Stella Neema, Andrea S Winkler","doi":"10.1007/s00103-025-04066-w","DOIUrl":"10.1007/s00103-025-04066-w","url":null,"abstract":"<p><strong>Background: </strong>Schistosomiasis remains a significant public health issue in Uganda, particularly among fishing communities. This study, nested within a larger community-based study (ADOPT) on introducing a new child-friendly praziquantel formulation for schistosomiasis, arpraziquantel, explored enablers and challenges perceived by district health authorities for implementing a mass drug administration (MDA) programme with arpraziquantel.</p><p><strong>Methods: </strong>Respondents in this cross-sectional study were purposively selected in Bugiri and Hoima districts, Uganda. Key informant interviews were conducted in July 2022 and thematically analysed using the World Health Organization health system building blocks framework.</p><p><strong>Results: </strong>In general, arpraziquantel is expected to be widely accepted, though some may oppose it for religious or political reasons, belief in witchcraft as a cause of schistosomiasis, or fear of side effects. High awareness of disease burden and the acceptance of the existing schistosomiasis MDA for adults and school-aged children were identified as enablers for successful implementation. Key implementation challenges include limited resources for sustained biannual MDAs, adequate remuneration of village health teams (VHTs), inadequate staff training, time constraints, uneven VHT workload, and weaknesses in the referral systems. Migration, difficulties sensitising mobile parents, and delayed meals due to poverty-complicating drug absorption requiring a full stomach-further hinder efforts.</p><p><strong>Discussion: </strong>This study underscores the importance of addressing health systems' challenges through targeted measures to ensure effective and sustainable MDA of arpraziquantel, including enhanced training of VHTs and other staff, sensitisation of parents and key stakeholders at all levels, and adequate responses to potentially emerging side effects.</p>","PeriodicalId":9562,"journal":{"name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","volume":" ","pages":"778-786"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Narrowing the health equity gap. How can implementation science proactively facilitate the cultural adaptation of public health innovations? 缩小卫生公平差距。实施科学如何积极促进公共卫生创新的文化适应?
IF 1.7 4区 医学
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Pub Date : 2025-07-01 Epub Date: 2025-05-21 DOI: 10.1007/s00103-025-04057-x
Zoe Fehlberg, Marlena Klaic, Samantha Croy, Stephanie Best
{"title":"Narrowing the health equity gap. How can implementation science proactively facilitate the cultural adaptation of public health innovations?","authors":"Zoe Fehlberg, Marlena Klaic, Samantha Croy, Stephanie Best","doi":"10.1007/s00103-025-04057-x","DOIUrl":"10.1007/s00103-025-04057-x","url":null,"abstract":"<p><p>While the ambitions of innovation in public health are usually geared towards improving health outcomes, an unintended consequence of the innovation process is that it can exacerbate health inequity. People who are disproportionately excluded from accessing the benefits from innovations in public health include, among others, minoritised racial and ethnic communities. Advancing racial and ethnic health equity by centring attention on systemic factors influencing health inequalities-for example, how structural racism influences public health-has gained much focus among researchers, including those in implementation science. Implementation science is a field ideally placed to actively intervene and enhance an equitable process of innovation. One of the key pieces in working towards implementing public health innovation that promotes health equity is progressing the science of adaptation. Cultural adaptation requires systematic changes to an intervention, context, or implementation activity to ensure the relevance and fit for a population, whilst retaining fidelity to the evidence-based components. In this discussion, we propose five implementation science approaches to proactively facilitate cultural adaptation in public health innovation and promote health equity. We discuss (1) structuring cultural adaptation through a formal process and (2) using theory, (3) incorporating inclusive and participatory approaches to cultural adaptation, (4) conceptualising cultural adaptation as an implementation strategy, and (5) investigating cultural adaptation to implementation science data collection tools. Further, we use an example of a precision public health program to exemplify a framework for reporting and making adaptations. Implementation science can use the practice of adaptation as part of the inclusive and equity-driven approaches to the implementation of public health innovation.</p>","PeriodicalId":9562,"journal":{"name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","volume":" ","pages":"809-817"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contextual factors of implementing APOL1 genetic testing into living kidney donor clinical evaluation. 在活体肾供者临床评价中实施APOL1基因检测的相关因素
IF 1.7 4区 医学
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Pub Date : 2025-07-01 Epub Date: 2025-06-11 DOI: 10.1007/s00103-025-04068-8
James L Merle, Marissa C Kuo, Jessica Gacki-Smith, Akansha Agrawal, John Friedewald, Elisa J Gordon, Justin D Smith
{"title":"Contextual factors of implementing APOL1 genetic testing into living kidney donor clinical evaluation.","authors":"James L Merle, Marissa C Kuo, Jessica Gacki-Smith, Akansha Agrawal, John Friedewald, Elisa J Gordon, Justin D Smith","doi":"10.1007/s00103-025-04068-8","DOIUrl":"10.1007/s00103-025-04068-8","url":null,"abstract":"<p><strong>Background: </strong>Living donor kidney transplantation (LDKT) is the preferred treatment for patients with end-stage kidney disease, offering longer graft survival and improved quality of life. However, LDKT poses risks to living donors. Black living donors face disproportionately higher risks of postdonation kidney disease than White counterparts, necessitating deeper understanding of the factors contributing to this disparity. This study evaluated the implementation of the APOL1 Genetic Testing and Counseling Program at two transplant centers to improve donors' informed decision-making, which entailed examining the contextual factors influencing its adoption and sustainment.</p><p><strong>Methods: </strong>We conducted a mixed-methods evaluation involving semistructured interviews guided by the Consolidated Framework for Implementation Research and surveys with transplant nephrologists to identify facilitators and barriers of intervention implementation.</p><p><strong>Results: </strong>Eleven nephrologists participated. Key facilitators included alignment with clinical priorities, strong organizational support, and value attributed to the intended goal of enhancing donors' informed consent process and to the integration of culturally sensitive counseling practices. Key barriers included time constraints and the need for clear evidence-based guidelines. Participants reported high acceptability, appropriateness, feasibility, and sustainability of the APOL1 Program.</p><p><strong>Conclusion: </strong>Our study identified facilitators and barriers that should be addressed to ensure the APOL1 program's sustainment and potential to improve donors' informed consent. Future research should leverage system-level implementation strategies to overcome identified barriers when taking the APOL1 Genetic Testing and Counseling Program to scale.</p>","PeriodicalId":9562,"journal":{"name":"Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz","volume":" ","pages":"758-768"},"PeriodicalIF":1.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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