Cardiology in Review最新文献_第2页

Hematological Complications From Transcatheter Aortic Valve Replacement (TAVR): Recognition and Treatment. 经导管主动脉瓣置换术（TAVR）的血液并发症：识别与治疗。

IF 2 4区医学

Cardiology in Review Pub Date : 2024-09-10 DOI: 10.1097/CRD.0000000000000785

Sahil Bhargava, Darshilkumar Maheta, Siddharth Pravin Agrawal, Maharshi Raval, William H Frishman, Wilbert S Aronow

{"title":"Hematological Complications From Transcatheter Aortic Valve Replacement (TAVR): Recognition and Treatment.","authors":"Sahil Bhargava, Darshilkumar Maheta, Siddharth Pravin Agrawal, Maharshi Raval, William H Frishman, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000785","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000785","url":null,"abstract":"Transcatheter aortic valve replacement (TAVR) has emerged as a pivotal intervention for patients with severe aortic stenosis who are at high or prohibitive surgical risk. Although TAVR is a minimally invasive procedure, it is linked to serious hematological problems, most notably thrombosis and bleeding. Numerous factors, such as procedural features, patient comorbidities, and anticoagulation management techniques, contribute to these complications. Bleeding complications can be major, minor, or life-threatening. They can be caused by problems with the vascular access site, anticoagulation medication, or coexisting conditions like renal dysfunction and frailty. Hemoglobin drop, overt bleeding, and hematoma signs must all be closely watched to identify bleeding. Careful selection and modification of anticoagulation medication, the use of vascular closure devices, and timely attention to bleeding sites are examples of management techniques. Thrombotic consequences, which include cerebrovascular accidents and valve thrombosis, are caused by endothelial injury, stent implantation, and patient hypercoagulability. Imaging modalities such as computed tomography and transesophageal echocardiography are used in the crucial process of detection. The goal of preventive care is to maximize anticoagulation regimens that are customized to each patient's risk profile, frequently striking a balance between the risk of thrombosis and bleeding. A multidisciplinary strategy that integrates surgical, hematological, and cardiology expertise is necessary for the effective management of these hematological complications. To improve patient outcomes, ongoing research attempts to improve risk stratification and create safer anticoagulation protocols. This review emphasizes how critical it is to identify bleeding and thrombotic events as soon as possible and treat them promptly to reduce the risk of negative outcomes for TAVR patients.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes of Surgical Versus Transcatheter Aortic Valve Replacement in Obese Patients: A Systematic Review and Meta-Analysis. 肥胖患者手术与经导管主动脉瓣置换术的结果：系统回顾与元分析》。

IF 2 4区医学

Cardiology in Review Pub Date : 2024-09-10 DOI: 10.1097/CRD.0000000000000767

Ileana Anika A Domondon, Deepapriya Jeyakumar, Mohammed Raake, Savitri Poornima Halaharvi, Fabeha Zafar, Samantha A Contreras Vazquez, Yozahandy A Abarca, Snehitha Reddy Goli, Divya Rohra, Farah Shah, Mohammed Sikander, Mohammed Al-Tawil

{"title":"Outcomes of Surgical Versus Transcatheter Aortic Valve Replacement in Obese Patients: A Systematic Review and Meta-Analysis.","authors":"Ileana Anika A Domondon, Deepapriya Jeyakumar, Mohammed Raake, Savitri Poornima Halaharvi, Fabeha Zafar, Samantha A Contreras Vazquez, Yozahandy A Abarca, Snehitha Reddy Goli, Divya Rohra, Farah Shah, Mohammed Sikander, Mohammed Al-Tawil","doi":"10.1097/CRD.0000000000000767","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000767","url":null,"abstract":"Transcatheter aortic valve implantation (TAVI) has been increasingly preferred over surgical aortic valve replacement (SAVR) for treating patients with severe aortic stenosis and intermediate to high surgical risk. Recent studies have indicated that obesity may confer protective benefits in cardiac surgery, known as the obesity paradox. We conducted a systematic review and meta-analysis to explore how obesity influences outcomes of TAVI versus SAVR. We searched and reviewed relevant studies comparing TAVI and SAVR in obese patients with aortic stenosis indexed in PubMed, Embase, and Scopus databases. Data from 5 studies with 16,161 patients (TAVI, n = 2951; SAVR, n = 13,210) were included. There was a lower incidence of postprocedural in-hospital mortality [risk ratio (RR), 0.64; 95% confidence interval (CI), 0.41-0.98; P = 0.04], acute kidney injury (RR, 0.53; 95% CI, 0.38-0.73; P = 0.0001), and shorter duration of in-hospital stay (mean difference: -3.35; 95% CI, -4.93 to -1.76; P = 0.0001) in TAVI versus SAVR. There was no significant difference in the risk of postoperative stroke (RR, 0.93; 95% CI, 0.29-3.02; P = 0.91), major bleeding (RR, 0.71; 95% CI, 0.47-1.07; P = 0.10), and myocardial infarction (RR, 0.64; 95% CI, 0.39-1.06; P = 0.08) between TAVI and SAVR. Higher incidences of PPM implantation (RR, 2.0; 95% CI, 1.38-2.90; P = 0.0003) and major vascular complications (RR, 1.51; 95% CI, 1.01-2.27; P = 0.05) were observed with TAVI. In obese patients, TAVI offers similar results as in the general population when compared with SAVR, except for increased vascular complications. An individualized approach can lead to optimal outcomes in this subpopulation.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vasopressor-Inotropic Score: Review of Literature. 血管加压-肌注评分：文献综述。

IF 2 4区医学

Cardiology in Review Pub Date : 2024-09-10 DOI: 10.1097/CRD.0000000000000781

Jackeline Flores, Kenneth Nugent

{"title":"Vasopressor-Inotropic Score: Review of Literature.","authors":"Jackeline Flores, Kenneth Nugent","doi":"10.1097/CRD.0000000000000781","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000781","url":null,"abstract":"Patients undergoing cardiac surgery often receive vasopressor and inotropic medications during the surgical procedure and during intensive care unit (ICU) management following surgery. Patients with cardiogenic shock, septic shock, and other clinical disorders associated with shock also receive vasopressor medications during their ICU care. The level of support and the duration of support are likely associated with outcomes, including mortality and new organ dysfunction, such as acute kidney injury. The vasopressor-inotropic score provides a simple method to determine the level of support during the care of these patients; this score includes the infusion rates of norepinephrine, epinephrine, dopamine, dobutamine, and other inotropic medications. It has been studied in patients undergoing cardiac surgery, coronary artery bypass grafting, cardiac transplantation, left ventricular assist device implantation, septic shock, and traumatic brain injury. Higher scores are associated with poor outcomes and complications during ICU care. The studies analyzed in this review demonstrate the utility of the vasopressor-inotropic score in a variety of clinical disorders associated with shock. Electronic medical record systems should develop algorithms to calculate this score and provide continuous up-to-date measurements. This could help clinicians identify patients at risk for mortality and important complications, such as acute kidney injury.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond the Gut: Exploring Cardiovascular Implications of Celiac Disease. 超越肠道：探索乳糜泻对心血管的影响。

IF 2 4区医学

Cardiology in Review Pub Date : 2024-09-10 DOI: 10.1097/CRD.0000000000000782

Sakshi Verma, Verkha Kumari, De-Kee Yangzom, Fnu Anamika, Kanishk Aggarwal, Bhupinder Singh, Rohit Jain

引用次数: 0

High- Versus Low-Dose Paclitaxel-Coated Balloons for Femoropopliteal Disease: A systematic review and meta-analysis. 高剂量与低剂量紫杉醇涂层球囊治疗股骨头疾病：系统回顾和荟萃分析。

IF 2 4区医学

Cardiology in Review Pub Date : 2024-09-10 DOI: 10.1097/CRD.0000000000000771

Gan Jin, Zhaokun Sun, Chunjiang Liu, Miaojun Xu

{"title":"High- Versus Low-Dose Paclitaxel-Coated Balloons for Femoropopliteal Disease: A systematic review and meta-analysis.","authors":"Gan Jin, Zhaokun Sun, Chunjiang Liu, Miaojun Xu","doi":"10.1097/CRD.0000000000000771","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000771","url":null,"abstract":"To evaluate the comparative effectiveness of high- and low doses of paclitaxel in endovascular revascularization procedures for patients with femoropopliteal disease. The databases (Embase, PubMed, Scopus, and Web of Science) were searched for studies that had compared outcomes of high-dose and low-dose paclitaxel-coated balloons (PCBs) in the treatment of patients with femoropopliteal disease. Randomized controlled trials and nonrandomized comparative studies (eg, cohort studies and case-control studies) were eligible for inclusion. The primary outcomes of interest were patency rates, risk of restenosis, and clinically-driven target lesion revascularization (CD-TLR). Pooled effect sizes were reported as relative risk (RR) with 95% confidence intervals (CI). The analysis included 7 studies. High-dose PCB use was associated with higher patency (RR, 1.10; 95% CI, 1.00-1.21), reduced risk of restenosis (RR, 0.60; 95% CI, 0.46-0.79), and reduced need for CT-TLR (RR, 0.57; 95% CI, 0.41-0.79) compared to low-dose PCB. Rates of limb salvage (RR, 1.01; 95% CI, 0.99-1.04), freedom from major adverse limb events (RR, 1.39; 95% CI, 0.79-2.42), and overall survival (RR, 1.02; 95% CI, 0.99-1.05) were comparable in the 2 groups. There was no evidence of publication bias. High-dose PCB correlates with superior outcomes in patients with femoropopliteal disease, particularly in terms of better vascular patency, reduced restenosis risk, and lower need for target lesion revascularization, compared to low-dose PCB.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prophylactic Effect of Aspirin and Other Medicine on Cerebral Infarction for Patients with Cardiovascular Diseases Risk Factors: A Systemic Review and Meta-Analysis. 阿司匹林和其他药物对心血管疾病危险因素患者脑梗塞的预防效果：系统回顾与元分析》。

IF 2 4区医学

Cardiology in Review Pub Date : 2024-09-10 DOI: 10.1097/CRD.0000000000000778

Binfei Gong, Weijiang Ye

{"title":"Prophylactic Effect of Aspirin and Other Medicine on Cerebral Infarction for Patients with Cardiovascular Diseases Risk Factors: A Systemic Review and Meta-Analysis.","authors":"Binfei Gong, Weijiang Ye","doi":"10.1097/CRD.0000000000000778","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000778","url":null,"abstract":"Stroke, as a type of cardiovascular disease (CVD) and cerebrovascular disease, has the risk of causing death or disability in patients. Aspirin, as an antipyretic and analgesic drug, can also treat or prevent CVDs. Previous studies have had conflicting results on the preventive effect of aspirin on cerebral infarction for patients with CVD risk factors. This review was carried out through a meticulous search of the Web of Science and PubMed databases. Articles were included or excluded based on predefined criteria. In terms of heterogeneity, a fixed effect model was utilized when I2 was less than 50%. Conversely, if the studies were deemed clinically comparable, a random effect model was implemented. The findings suggest that medical intervention significantly mitigates the risk of cerebral infarction in patients predisposed to CVDs [odds ratio (OR), 0.85; 95% confidence interval (CI), 0.74-0.98; P = 0.03]. Interestingly, the preventive efficacy of medication appears to be higher in men (OR, 0.82; 95% CI, 0.72-0.94; P = 0.004) than in women (OR, 0.84; 95% CI, 0.69-1.01; P = 0.06). However, in terms of stroke prevention, no significant difference was observed between the use of aspirin (OR, 0.90; 95% CI, 0.76-1.06; P = 0.19) and other medications (OR, 0.65; 95% CI, 0.31-1.38; P = 0.26).","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anticoagulation Strategies in Post-LAA Closure Ablation for Atrial Fibrillation: A Research Imperative. 心房颤动 LAA 封闭消融术后的抗凝策略：研究的当务之急。

IF 2 4区医学

Cardiology in Review Pub Date : 2024-09-05 DOI: 10.1097/CRD.0000000000000788

Ali Saad Al-Shammari, Hamza Tariq, Ahmed Ibrahim, Amira Mohamed Taha, Ammar Sattar Ibrahim, Mohammed Hado, Narayanan Chockalingam, Muhie Dean Sabayon, Haider Al Taii

引用次数: 0

Transcatheter Aortic Valve Implantation (TAVI) in Bicuspid Aortic Valve Disease: A Systematic Review. 双尖瓣主动脉瓣疾病的经导管主动脉瓣植入术（TAVI）：系统回顾。

IF 2 4区医学

Cardiology in Review Pub Date : 2024-09-05 DOI: 10.1097/CRD.0000000000000784

Christopher J Goulden, Kelly Wright, Samina Alim, Nikhil Patel, Mahnoor Irfan, Dilşat Onay, Cameron Sabet, Dang Nguyen, Amer Harky

{"title":"Transcatheter Aortic Valve Implantation (TAVI) in Bicuspid Aortic Valve Disease: A Systematic Review.","authors":"Christopher J Goulden, Kelly Wright, Samina Alim, Nikhil Patel, Mahnoor Irfan, Dilşat Onay, Cameron Sabet, Dang Nguyen, Amer Harky","doi":"10.1097/CRD.0000000000000784","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000784","url":null,"abstract":"Transcatheter aortic valve implantation (TAVI) is effective and safe, but its outcomes for patients with bicuspid aortic valve (BAV) disease are relatively unclear. A comprehensive search of PubMed, Medline, and Google Scholar till November 2023 yielded studies evaluating TAVI in BAV patients. Inclusion criteria were applied, and data were extracted on clinical and procedural outcomes, including echocardiographic measures and complications. Statistical analyses included descriptive statistics, subgroup analysis, and sensitivity analysis. From the 29 studies covering 8045 BAV patients, the mean age was found to be 72.5 ± 10.35 years with a male predominance of 56.4% ± 7.9%. TAVI was significantly beneficial, decreasing the mean aortic gradient from 46.9 to 10.4 mm Hg postprocedure and increasing aortic valve area, evidencing improved hemodynamics. A high procedural success rate of 93.3% was noted, predominantly through femoral access. However, complications included pacemaker need (12.6%), minor bleeding, and acute kidney injury. All-cause mortality escalated from 3.7% perioperatively to 16.8% after 1 year. Hazard ratios and P values highlighted significant outcomes: perioperative hazard ratio for mortality at 3.7% (P < 0.05), reduction in perioperative versus postoperative gradients (P < 0.001), and increase in postoperative aortic valve area (P < 0.001). The need for postdilatation was less than predilatation (P < 0.05), and significant differences were noted in device sizes (P < 0.05). TAVI in BAV patients showed good perioperative outcomes but with moderate complication rates. Notably, there was a significant rise in 1-year mortality, underscoring the importance of careful patient selection and strict postoperative care. More studies are necessary to determine long-term results and refine procedures for this group.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142131944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Supranormal Left Ventricular Function With Major Adverse Cardiovascular Events: A Systematic Review of Literature. 左心室功能超常与主要不良心血管事件的关系：文献系统回顾

IF 2 4区医学

Cardiology in Review Pub Date : 2024-09-05 DOI: 10.1097/CRD.0000000000000783

Abdul Rahim, Muhammad Umer Riaz Gondal, Farman Ali, Asif Ullah, Atta Ul Haq Burki, Danesh Kumar, Hari Vishal, Arham Iqbal, Jahanzeb Malik

{"title":"Association of Supranormal Left Ventricular Function With Major Adverse Cardiovascular Events: A Systematic Review of Literature.","authors":"Abdul Rahim, Muhammad Umer Riaz Gondal, Farman Ali, Asif Ullah, Atta Ul Haq Burki, Danesh Kumar, Hari Vishal, Arham Iqbal, Jahanzeb Malik","doi":"10.1097/CRD.0000000000000783","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000783","url":null,"abstract":"This systematic review aims to assess the prognostic implications of supranormal left ventricular ejection fraction (snLVEF) in cardiovascular disease, particularly heart failure (HF), and explore its association with major adverse cardiovascular events (MACE). A comprehensive search of electronic databases was conducted to identify relevant studies examining the relationship between snLVEF and cardiovascular outcomes. Studies utilizing various imaging modalities, including echocardiography, cardiac positron emission tomography, computed tomography, and cardiac magnetic resonance imaging, were included. Data extraction and quality assessment were performed according to predefined criteria. The review identified several studies investigating the association between snLVEF and cardiovascular outcomes. Findings revealed an increased risk of MACE, including HF hospitalization and stroke, in patients with snLVEF, particularly in women. Coronary microvascular dysfunction and autonomic dysregulation were proposed mechanisms underlying these associations. However, conflicting results were observed when focusing exclusively on snLVEF, with some studies reporting similar outcomes between snLVEF and other HF subgroups. snLVEF (>65%) appears to be associated with an elevated risk of MACE, particularly in women, suggesting a U-shaped mortality curve. However, the prognostic implications may vary among HF patients, necessitating further research to elucidate the specific contributions of HF phenotypes and comorbidities. These findings underscore the importance of tailored risk assessment and management strategies for patients with snLVEF, particularly in the context of HF.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142131943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association Between Cardiovascular Disease and Dementia: A Review of Trends in Epidemiology, Risk Factors, Pathophysiologic Mechanisms, and Clinical Implications. 心血管疾病与痴呆之间的关联：流行病学趋势、风险因素、病理生理学机制和临床意义综述》（A Review of Trends in Epidemiology, Risk Factors, Pathophysiologic Mechanisms, and Clinical Implications）。

IF 2 4区医学

Cardiology in Review Pub Date : 2024-09-01 Epub Date: 2023-03-22 DOI: 10.1097/CRD.0000000000000523

Maya Pandit, William H Frishman

{"title":"The Association Between Cardiovascular Disease and Dementia: A Review of Trends in Epidemiology, Risk Factors, Pathophysiologic Mechanisms, and Clinical Implications.","authors":"Maya Pandit, William H Frishman","doi":"10.1097/CRD.0000000000000523","DOIUrl":"10.1097/CRD.0000000000000523","url":null,"abstract":"With increases in life expectancy and the size of the aging population, cognitive decline and neurodegenerative pathologies are expected to increase in the next few decades. Age-related increases in risk for dementia and cardiovascular disease have been researched widely. Epidemiology trends reveal a predicted increase of neurodegenerative disease to more than 65 million by 2030 in the United States. There are several risk factors for the development of cardiovascular disease that have been widely studied for their impact on dementia; such as: diabetes, hypertension, and hyperlipidemia. Several pathophysiologic mechanisms exist by which cardiovascular disease could impact dementia including cerebral hypoperfusion, reactive oxidative species, and increased cleavage of amyloid precursor protein into amyloid beta plaques and accumulation of neurofibrillary tangles. Emerging evidence also suggests that treatment of cardiovascular disease risk factors could reduce the risk of dementia development. In this review, we seek to examine the relationship between cardiovascular disease and dementia by examining epidemiologic trends, common risk factors, pathophysiologic mechanisms and implications for clinical management.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9525425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0