Cardiology in Review最新文献

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Review and Key Takeaways of the 2021 Percutaneous Coronary Intervention Guidelines. 2021年经皮冠状动脉介入治疗指南的回顾和关键要点。
IF 2 4区 医学
Cardiology in Review Pub Date : 2025-03-01 Epub Date: 2023-09-20 DOI: 10.1097/CRD.0000000000000608
Haris Patail, Atul Bali, Tanya Sharma, William H Frishman, Wilbert S Aronow
{"title":"Review and Key Takeaways of the 2021 Percutaneous Coronary Intervention Guidelines.","authors":"Haris Patail, Atul Bali, Tanya Sharma, William H Frishman, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000608","DOIUrl":"10.1097/CRD.0000000000000608","url":null,"abstract":"<p><p>The 2021 Percutaneous Coronary Intervention guidelines completed by American College of Cardiology/American Heart Association/Society for Cardiovascular Angiography and Interventions provide a set of guidelines regarding revascularization strategies. With emphasis on equity of care, multidisciplinary heart team use, revascularization for acute coronary syndrome, and stable ischemic heart disease, the guidelines create a thorough framework with recommendations regarding therapeutic strategies. In this comprehensive review, our aim is to summarize the 2021 revascularization guidelines and analyze key points regarding each recommendation.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":"178-186"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41119622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Concise Review of Marfan Syndrome with a Congenital Cardiac Surgery Focus. 以先天性心脏外科为重点的马凡氏综合症简明综述。
IF 2 4区 医学
Cardiology in Review Pub Date : 2025-03-01 Epub Date: 2024-10-24 DOI: 10.1097/CRD.0000000000000619
Andrew D Vogel, Gabriela M Galan, T Konrad Rajab
{"title":"A Concise Review of Marfan Syndrome with a Congenital Cardiac Surgery Focus.","authors":"Andrew D Vogel, Gabriela M Galan, T Konrad Rajab","doi":"10.1097/CRD.0000000000000619","DOIUrl":"10.1097/CRD.0000000000000619","url":null,"abstract":"<p><p>Marfan syndrome is named after Antoine Marfan, who described a 5-year-old child with congenital elongation of the digits and other skeletal abnormalities in 1896. While Marfan syndrome is a systemic connective tissue disorder predominantly involving the skeletal, cardiovascular, and ocular systems, the cardiovascular system presents the most life-threatening complications. Most cardiovascular pathologies surround the left ventricular outflow tract and aorta, with aortic dissection requiring emergent surgical management to the progression of mitral regurgitation requiring elective surgery. Intensive care management, along with a tailored approach to the surgical management of a patient with Marfan syndrome, is critical to their survival. Current surgical operations for patients include aortic root surgery, valve-sparing root replacements, aortic root replacements with conduits, and mitral valve repairs. Further research is necessary to determine the molecular, endovascular, pharmaceutical, and surgical management of Marfan syndrome. This review attempts to concisely discuss the diagnosis, complications, and medical and intensive care management of Marfan syndrome while further divulging on the surgical management of those with this disease process.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":"166-170"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142495706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left Atrial Appendage Closure: What Do We Know? 左心耳闭合:我们知道些什么?
IF 2 4区 医学
Cardiology in Review Pub Date : 2025-03-01 Epub Date: 2023-08-29 DOI: 10.1097/CRD.0000000000000601
Savalan Babapoor-Farrokhran, Jafar Alzubi, Zachary Port, Risheek Kaul, Roozbeh Tarighati Rasekhi, Ali Babapour Farrokhran, Naveen Sooknanan, Philip C Wiener, Ola Khraisha, William H Frishman, Sumeet K Mainigi, Wilbert S Aronow
{"title":"Left Atrial Appendage Closure: What Do We Know?","authors":"Savalan Babapoor-Farrokhran, Jafar Alzubi, Zachary Port, Risheek Kaul, Roozbeh Tarighati Rasekhi, Ali Babapour Farrokhran, Naveen Sooknanan, Philip C Wiener, Ola Khraisha, William H Frishman, Sumeet K Mainigi, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000601","DOIUrl":"10.1097/CRD.0000000000000601","url":null,"abstract":"<p><p>Atrial fibrillation (AF) is the most common arrhythmia in the United States and the most common cause of embolic cerebrovascular events, with the majority of these thrombi originating in the left atrial appendage. The left atrial appendage (LAA) has separate developmental, ultrastructural, and physiological characteristics from the left atrium. Although LAA anatomy is highly variable, it can be categorized into 4 types: cactus, cauliflower, chicken wing, and windsock. The cauliflower type is associated with higher stroke risk in patients with nonvalvular AF. Although the cornerstone of therapy to prevent embolic strokes from AF has been anticoagulation with thrombin inhibitors, a large group of patients are unable to tolerate anticoagulation due to bleeding. This has led to the development and advancement of multiple surgical and percutaneous LAA closure devices to prevent embolic cerebrovascular accidents without the need for anticoagulation. In this article, we discuss the outcomes of major studies that utilized surgical LAA occlusion and its effectiveness. Furthermore, we summarize nonsurgical methods of LAA closure and future directions regarding LAA closure.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":"153-159"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10103705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PCSK9 Inhibitors - A New Hope for Dyslipidemia in HIV. PCSK9抑制剂——治疗HIV血脂异常的新希望
IF 2 4区 医学
Cardiology in Review Pub Date : 2025-03-01 Epub Date: 2023-11-29 DOI: 10.1097/CRD.0000000000000587
Sanjana Datla, Sundeep Kumar
{"title":"PCSK9 Inhibitors - A New Hope for Dyslipidemia in HIV.","authors":"Sanjana Datla, Sundeep Kumar","doi":"10.1097/CRD.0000000000000587","DOIUrl":"10.1097/CRD.0000000000000587","url":null,"abstract":"<p><p>Cardiovascular disease has become increasingly prevalent in the HIV population. Antiretroviral therapy and HIV itself independently increase the risk of dyslipidemia. While statins are currently the predominant therapy to treat dyslipidemia in HIV patients, drug-drug interactions and adverse drug events can limit their use. Proprotein convertase subtilisin/kexin type 9 inhibitors have shown promising results in preliminary trials by significantly reducing low density lipoprotein and other atherogenic lipid levels. They should be considered as an early intervention alongside statins in HIV patients with dyslipidemia.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":"112-113"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138450925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Implication of Preprocedural Pulmonary Hypertension in Patients with Severe Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis. 接受经导管主动脉瓣植入术的重度主动脉瓣狭窄患者术前肺动脉高压的预后影响:系统综述与 Meta 分析》。
IF 2 4区 医学
Cardiology in Review Pub Date : 2025-03-01 Epub Date: 2024-01-29 DOI: 10.1097/CRD.0000000000000583
Mahmood Emami Meybodi, Atefe Bamarinejad, Fateme Bamarinejad, Amir Parsa Abhari, Mohammad Fakhrolmobasheri, Fareheh Khosravi Larijani, Shidrokh Nasiri, Davood Shafie
{"title":"Prognostic Implication of Preprocedural Pulmonary Hypertension in Patients with Severe Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis.","authors":"Mahmood Emami Meybodi, Atefe Bamarinejad, Fateme Bamarinejad, Amir Parsa Abhari, Mohammad Fakhrolmobasheri, Fareheh Khosravi Larijani, Shidrokh Nasiri, Davood Shafie","doi":"10.1097/CRD.0000000000000583","DOIUrl":"10.1097/CRD.0000000000000583","url":null,"abstract":"<p><p>Pulmonary hypertension (PH) is a common comorbidity in patients with aortic stenosis (AS) who are candidates for transcatheter aortic valve implantation (TAVI). Herein, we sought to elucidate the prognostic value of preprocedural PH on the early and late mortality after TAVI. The Cochrane Library, Scopus, PubMed, Web of Science, Embase, and ProQuest were screened using a predefined search query. We considered odds ratios (ORs) as the measure of effect. Meta-regression analysis was applied to investigate the potential impact of baseline characteristics on the outcomes. Egger's and Begg's tests were used to assess the publication bias. Thirty-three studies comprising 34 datasets representing 68,435 patients were included in the analysis. Regardless of the definition and severity of PH, pooled data analysis indicated that preprocedural PH was associated with higher cardiac and overall 30-day [OR, 1.45 (1.15-1.82) and OR, 1.75 (1.42-2.17), respectively], and 1-year mortality [OR, 1.63 (1.35-1.96) and OR, 1.59 (1.38-1.82), respectively]. Meta-regression analysis demonstrated that older age, higher New York Heart Association function class, history of hypertension, diabetes, and lower left ventricular ejection fraction were predictors of higher mortality rate following TAVI. Moreover, we found that preprocedural PH is significantly associated with higher in-hospital mortality and 30-day acute kidney injury. Our results demonstrated that preprocedural PH is associated with higher early and late cardiac and overall mortality following TAVI; however, this finding is limited regarding the considerable inconsistency in the definition of PH and PH severity among studies.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":"120-128"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding the Interplay between Iron Deficiency and Congestive Heart Failure: A comprehensive review. 了解缺铁和充血性心力衰竭之间的相互作用:一个全面的回顾。
IF 2 4区 医学
Cardiology in Review Pub Date : 2025-03-01 Epub Date: 2023-08-29 DOI: 10.1097/CRD.0000000000000603
Kopal Kotak, Kanishk Aggarwal, Shreya Garg, Vasu Gupta, Fnu Anamika, Rohit Jain
{"title":"Understanding the Interplay between Iron Deficiency and Congestive Heart Failure: A comprehensive review.","authors":"Kopal Kotak, Kanishk Aggarwal, Shreya Garg, Vasu Gupta, Fnu Anamika, Rohit Jain","doi":"10.1097/CRD.0000000000000603","DOIUrl":"10.1097/CRD.0000000000000603","url":null,"abstract":"<p><p>Iron is an essential micronutrient for abounding physiological processes in the body, and its deficiency can be caused by various factors, such as low iron intake due to economic difficulties or loss of appetite, decreased iron absorption due to gastrointestinal issues, or increased iron loss due to hemorrhages or proteinuria. Iron deficiency is a prevalent issue among heart failure (HF) patients and is a significant contributor to anemia, affecting 30-50% of patients regardless of their gender, ethnicity, or left ventricular ejection fraction. Individuals with HF have high levels of pro-inflammatory cytokines, which can inhibit erythropoiesis by degrading the membrane iron exporter ferroportin, mediated by an increased release of hepcidin. In addition, elevated sympathetic and renin-angiotensin-aldosterone system activity retains salt and water, resulting in high cardiac output HF in people with normal left ventricular function. This review provides an overview of iron deficiency and HF.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":"171-177"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10109910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiotoxicity of Breast Cancer Chemotherapy. 乳腺癌化疗的心脏毒性。
IF 2 4区 医学
Cardiology in Review Pub Date : 2025-03-01 Epub Date: 2025-02-03 DOI: 10.1097/CRD.0000000000000589
Sacha A Roberts, William H Frishman
{"title":"Cardiotoxicity of Breast Cancer Chemotherapy.","authors":"Sacha A Roberts, William H Frishman","doi":"10.1097/CRD.0000000000000589","DOIUrl":"10.1097/CRD.0000000000000589","url":null,"abstract":"<p><p>Breast cancer is one of the leading causes of malignancy affecting women in the United States. Although many effective treatments are available, most come with notable side effects that providers and patients must take into consideration. Various classes of chemotherapeutic agents, including anthracyclines and human epidermal growth factor receptor-2 antagonists, are known to be toxic to myocardial tissue. In this review article, we discuss what is reported in the literature regarding the cardiotoxicity of these agents as well as how to monitor and prevent cardiac injury and dysfunction.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":"109-111"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10137894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Istaroxime: A Novel Therapeutic Agent for Acute Heart Failure. 依他肟:一种治疗急性心力衰竭的新型药物。
IF 2 4区 医学
Cardiology in Review Pub Date : 2025-03-01 Epub Date: 2023-10-09 DOI: 10.1097/CRD.0000000000000598
Danielle Newbury, William Frishman
{"title":"Istaroxime: A Novel Therapeutic Agent for Acute Heart Failure.","authors":"Danielle Newbury, William Frishman","doi":"10.1097/CRD.0000000000000598","DOIUrl":"10.1097/CRD.0000000000000598","url":null,"abstract":"<p><p>Acute decompensated heart failure (ADHF) is a multifactorial process that is associated with high morbidity and mortality. Treatment with inotropes can rapidly improve hemodynamic status; however, their use has been associated with increased mortality and incidence of arrhythmias. Istaroxime is a first-in-class intravenous agent currently undergoing clinical trials for acute heart failure. It has the unique mechanism of action of both Na + /K + ATPase inhibition and sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2a stimulation. Notably, its action on sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2a improves calcium handling, which is known to be abnormal in heart failure. Clinical trials have shown that istaroxime has beneficial hemodynamic effects; in particular, its ability to increase systolic blood pressure without causing significant increases in heart rate or clinically significant arrhythmias differentiates it from inotropes currently utilized for ADHF treatment, such as milrinone. While initial studies are encouraging, additional trials are needed to assess outcomes and to compare their performance to standard inotropes in patients hospitalized with ADHF. This article will review the relevant preclinical and clinical trials for istaroxime, as well as the relevant pharmacology.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":"187-190"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41105469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Therapy Update Aprocitentan: An Endothelin Receptor Antagonist for the Treatment of Drug-Resistant Systemic Hypertension. 阿普昔坦:一种内皮素受体拮抗剂治疗耐药全身性高血压。
IF 2 4区 医学
Cardiology in Review Pub Date : 2025-03-01 Epub Date: 2023-08-02 DOI: 10.1097/CRD.0000000000000591
Michael Airo, WIlliam H Frishman, Wilbert S Aronow
{"title":"New Therapy Update Aprocitentan: An Endothelin Receptor Antagonist for the Treatment of Drug-Resistant Systemic Hypertension.","authors":"Michael Airo, WIlliam H Frishman, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000591","DOIUrl":"10.1097/CRD.0000000000000591","url":null,"abstract":"<p><p>Resistant hypertension (RH) is the state of uncontrolled blood pressure in the face of ostensibly optimal pharmacological intervention. It accounts for roughly one in six cases of hypertension, and is associated with more severe morbidity and mortality outcomes than is non-RH. The prevalence of RH implies a currently unmanaged pathology, which may involve the potent vasoconstrictor endothelin. Several endothelin receptor antagonists are currently marketed for pulmonary arterial hypertension, but none so far has been marketed for RH. Aprocitentan is currently in development, an endothelin receptor antagonist that effectively produces clinically significant and sustained decreases in systolic and diastolic blood pressure in the setting of RH.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":"114-119"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9917712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long Saphenous Vein Harvesting: Reviewing Various Techniques. 长隐静脉采收:各种技术综述。
IF 2 4区 医学
Cardiology in Review Pub Date : 2025-03-01 Epub Date: 2023-07-03 DOI: 10.1097/CRD.0000000000000580
Momna Sajjad Raja, Bea Duric, Arwa Khashkhusha, Hannah Abbasi, Kartik Goyal, Amer Harky
{"title":"Long Saphenous Vein Harvesting: Reviewing Various Techniques.","authors":"Momna Sajjad Raja, Bea Duric, Arwa Khashkhusha, Hannah Abbasi, Kartik Goyal, Amer Harky","doi":"10.1097/CRD.0000000000000580","DOIUrl":"10.1097/CRD.0000000000000580","url":null,"abstract":"<p><p>Ischemic heart disease is the leading cause of mortality and morbidity in the Western world. Thus, coronary artery bypass graft is the most common cardiac procedure performed as it remains the gold standard for multiple vessel disease and left main disease. Long saphenous vein is the conduit of choice for coronary artery bypass graft as it is accessible and easy to harvest. Over the previous 4 decades, several techniques have emerged to optimize harvesting and reducing adverse clinical outcomes. The most cited techniques are open vein harvesting, no-touch technique, endoscopic vein harvesting, and standard bridging technique. In this literature review, we aim to summarize current literature for each of the 4 techniques in terms of: (A) graft patency and attrition, (B) myocardial infarction and revascularization, (C) wound infections, (D) postoperative pain, and (E) patient satisfaction.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":"102-108"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9740479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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