Cardiology in Review最新文献

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Efficacy of Sentinel Cerebral Embolic Protection Device in Transcatheter Aortic Valve Replacement: A Meta-Analysis of Randomized Controlled Trials and Propensity Score-Matched Studies. 经导管主动脉瓣置换术中哨兵脑栓塞保护装置的疗效:随机对照试验和倾向评分匹配研究的 Meta 分析。
IF 2 4区 医学
Cardiology in Review Pub Date : 2024-09-30 DOI: 10.1097/CRD.0000000000000797
Hritvik Jain, Neha Pervez, Debankur Dey, Ramez M Odat, Jyoti Jain, Aman Goyal, Anmol Saggar, Ayham Mohammad Hussein, Aniket Mathur, Sukul Khanna, Raheel Ahmed, Farhan Shahid
{"title":"Efficacy of Sentinel Cerebral Embolic Protection Device in Transcatheter Aortic Valve Replacement: A Meta-Analysis of Randomized Controlled Trials and Propensity Score-Matched Studies.","authors":"Hritvik Jain, Neha Pervez, Debankur Dey, Ramez M Odat, Jyoti Jain, Aman Goyal, Anmol Saggar, Ayham Mohammad Hussein, Aniket Mathur, Sukul Khanna, Raheel Ahmed, Farhan Shahid","doi":"10.1097/CRD.0000000000000797","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000797","url":null,"abstract":"<p><p>Transcatheter aortic valve replacement (TAVR) is frequently associated with stroke due to debris embolization. Although the risk of stroke with newer-generation devices is lower, stroke still represents a significant cause of mortality and morbidity post-TAVR. The Sentinel cerebral embolic protection device (CEPD) is a dual-embolic filter device designed to capture debris dislodged during TAVR. A systematic literature search was performed on the major bibliographic databases to retrieve studies that compared TAVR with and without Sentinel CEPD. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using the DerSimonian-Laird random-effects model, with a P value of <0.05 considered statistically significant. This meta-analysis included 6 studies with 25,130 patients undergoing TAVR (12,608: Sentinel CEPD; 12,522: without Sentinel CEPD). The use of the Sentinel CEPD in TAVR was associated with a statistically significant lower risk of acute kidney injury (OR: 0.89; 95% CI: 0.81-0.97; P = 0.01]. The use of Sentinel CEPD in TAVR was associated with a statistically insignificant trend toward a reduction in stroke (OR: 0.80; 95% CI: 0.58-1.10; P = 0.18), all-cause mortality (OR: 0.74; 95% CI: 0.51-1.07; P = 0.11), and major vascular complications (OR: 0.74; 95% CI: 0.46-1.19; P = 0.21). The use of Sentinel CEPD in patients undergoing TAVR does not lead to a statistically significant reduction in stroke, all-cause mortality, or major vascular complications; however, the risk of acute kidney injury is lower. Further randomized studies are warranted to confirm these findings.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Curbside Consults Salt-Free Potassium-Enriched Substitute Versus Salt-Free Diet in Hypertension: Which Is Better?
IF 2 4区 医学
Cardiology in Review Pub Date : 2024-09-26 DOI: 10.1097/CRD.0000000000000795
Dev Desai, Siddharth Pravin Agrawal, Darshilkumar Maheta, Ahmed Gamal Abouarab, William H Frishman, Wilbert S Aronow
{"title":"Curbside Consults Salt-Free Potassium-Enriched Substitute Versus Salt-Free Diet in Hypertension: Which Is Better?","authors":"Dev Desai, Siddharth Pravin Agrawal, Darshilkumar Maheta, Ahmed Gamal Abouarab, William H Frishman, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000795","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000795","url":null,"abstract":"<p><p>This article examines the potential benefits of using potassium-enriched salt and following a salt-free diet to control hypertension, a prevalent global condition and a major risk factor for heart disease, stroke, and kidney disease. The article explores the impact of sodium on high blood pressure, explains what potassium-fortified salt is, and includes personal experiences. The article also examines the scientific proof backing potassium-fortified salt, evaluating its advantages and constraints. It subsequently assesses the advantages and disadvantages of a diet without salt, with the goal of providing readers with thorough information to help them make educated choices. The article emphasizes the significance of nutrition in averting noncommunicable diseases, especially heart-related issues associated with hypertension. The conversation focuses on the benefits of potassium-rich salt and salt-free diets for controlling high blood pressure and improving heart health. It acts as a stimulus for additional research and intervention tactics focused on reducing hypertension and its related health complications. Choosing potassium-enriched salts or embracing a salt-free diet is a wise decision to prevent hypertension, encouraging a collective effort to promote dietary awareness and optimize health.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiovascular Manifestations of Pseudoxanthoma Elasticum: Pathophysiology, Management, and Research. 假黄瘤的心血管表现:病理生理学、管理与研究》(Pseudoxanthoma Elasticum: Pathophysiology, Management, and Research)。
IF 2 4区 医学
Cardiology in Review Pub Date : 2024-09-26 DOI: 10.1097/CRD.0000000000000796
Dev Desai, Darshilkumar Maheta, Siddharth Pravin Agrawal, Zeal Soni, William H Frishman, Wilbert S Aronow
{"title":"Cardiovascular Manifestations of Pseudoxanthoma Elasticum: Pathophysiology, Management, and Research.","authors":"Dev Desai, Darshilkumar Maheta, Siddharth Pravin Agrawal, Zeal Soni, William H Frishman, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000796","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000796","url":null,"abstract":"<p><p>Pseudoxanthoma elasticum is a rare genetic disorder characterized by calcification of elastic fibers in the connective tissue. The abundance of elastic tissues at these sites: skin, eyes, and heart make them the most affected systems. It has multifactorial pathogenesis, meaning, it manifests due to both environmental and genetic factors, but ABCC6 gene mutation plays an important role. This gene is responsible for causing defective MRP6 protein which in return is required for cell transport in the connective tissue. The clinical features range from minor skin lesions to fatal cardiovascular complications. Thus, it is important to diagnose it early and give appropriate treatment. This article provides insight into the cardiovascular manifestations of pseudoxanthoma elasticum, its diagnosis and management plans.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antithrombotic Strategies After Transcatheter Aortic Valve Replacement in Patients Without an Indication of Oral Anticoagulants: A Network Meta-Analysis of Randomized Controlled Trials. 无口服抗凝药适应症患者经导管主动脉瓣置换术后的抗血栓策略:随机对照试验网络 Meta 分析》。
IF 2 4区 医学
Cardiology in Review Pub Date : 2024-09-26 DOI: 10.1097/CRD.0000000000000791
Ahmed K Awad, Mohamed Abuelazm, Govinda Adhikari, Ahmed Mazen Amin, Mahmoud M Elhady, Ayman K Awad, Abdelrahman Mahmoud, Ahmed R Gonnah, Basel Abdelazeem
{"title":"Antithrombotic Strategies After Transcatheter Aortic Valve Replacement in Patients Without an Indication of Oral Anticoagulants: A Network Meta-Analysis of Randomized Controlled Trials.","authors":"Ahmed K Awad, Mohamed Abuelazm, Govinda Adhikari, Ahmed Mazen Amin, Mahmoud M Elhady, Ayman K Awad, Abdelrahman Mahmoud, Ahmed R Gonnah, Basel Abdelazeem","doi":"10.1097/CRD.0000000000000791","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000791","url":null,"abstract":"<p><p>Single-antiplatelet therapy (SAPT) has been a standard of care posttranscatheter aortic valve replacement with no clear evidence exist using direct oral anticoagulants (DOACs), vitamin K antagonists (VKA), or dual antiplatelet agents (DAPT); thus we aim to compare the safety and efficacy of the various antithrombotic strategies after transcatheter aortic valve replacement. We performed a network meta-analysis using a frequentist framework, pooling dichotomous outcomes using risk ratio (RR), and continuous data using mean difference, along with the corresponding 95% confidence interval (CI). Nine randomized controlled trials with 4193 patients were included, 567 patients were in the VKA group, 591 patients in the SAPT group, 1571 patients in the DAPT group, and 1464 patients in the DOACs group. Only DOAC showed a statistically significant higher risk of all-cause mortality [RR of 1.88 (95% CI: 1.07-3.28)] with no statistically significant difference between our arms in terms of mortality. For minor bleeding, DAPT had a significant higher risk with RR of 1.53 (95% CI: 1.04-2.25), while for major bleeding, DAPT and DOAC had a significant higher risk with RR of 2.36 (95% CI: 1.27-4.40) and 4.74 (95% CI: 2.05-10.92), respectively. There was no significant difference in terms of stroke and life-threatening bleeding. Moreover, only DOAC showed a significantly lower risk for valve thrombosis, when compared to other strategies [RR: 0.24 (95% CI: 0.13-0.46)]. Overall, SAPT had lower major bleeding events compared to other arms. There were no differences in the outcomes of stroke, myocardial infarction, or life-threatening bleeding outcomes. However, DOACs significantly reduced valve thrombosis compared to VKAs.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronary Artery Anomalies: Diagnosis & Management. 冠状动脉异常:诊断与管理》。
IF 2 4区 医学
Cardiology in Review Pub Date : 2024-09-23 DOI: 10.1097/CRD.0000000000000786
Sanjay Chandrasekhar, Edward Woods, Josiah Bennett, Noah Newman, Patrick McLean, Mahboob Alam, Hani Jneid, Samin Sharma, Muzamil Khawaja, Chayakrit Krittanawong
{"title":"Coronary Artery Anomalies: Diagnosis & Management.","authors":"Sanjay Chandrasekhar, Edward Woods, Josiah Bennett, Noah Newman, Patrick McLean, Mahboob Alam, Hani Jneid, Samin Sharma, Muzamil Khawaja, Chayakrit Krittanawong","doi":"10.1097/CRD.0000000000000786","DOIUrl":"10.1097/CRD.0000000000000786","url":null,"abstract":"<p><p>Coronary artery anomalies encompass a spectrum of congenital abnormalities affecting the origin, course, or termination of the major epicardial coronary arteries. Despite their rarity, coronary artery anomalies represent a significant burden on cardiovascular health due to their potential to disrupt myocardial blood flow and precipitate adverse cardiac events. While historically diagnosed postmortem, the widespread availability of imaging modalities has led to an increased recognition of coronary artery anomalies, particularly in adults. This review synthesizes current knowledge on the classification, mechanisms, and clinical implications of coronary anomalies, focusing on prevalent variants with significant clinical impact. We discuss strategies for medical and surgical management, as well as contemporary screening recommendations, acknowledging the evolving understanding of these anomalies. Given the breadth of possible variants and the limited data on some presentations, this review provides a framework to aid clinicians in the recognition and management of coronary anomalies, with a particular emphasis on their stratification by anatomical location. By consolidating existing knowledge and highlighting areas of uncertainty, this review aims to enhance clinical decision-making and improve outcomes for individuals with coronary anomalies.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discontinuation of Cardiac Devices at or Near an Adult Patient's End of Life. 在成年患者生命末期或临近生命末期停用心脏设备。
IF 2 4区 医学
Cardiology in Review Pub Date : 2024-09-16 DOI: 10.1097/CRD.0000000000000789
John Arthur McClung, William H Frishman, Wilbert S Aronow
{"title":"Discontinuation of Cardiac Devices at or Near an Adult Patient's End of Life.","authors":"John Arthur McClung, William H Frishman, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000789","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000789","url":null,"abstract":"<p><p>Advances in medical technology have begun to blur the lines between life and death as well as the lines between appropriate and inappropriate therapy. This review addresses the charged issue of the management of cardiac devices at or near the end of a patient's life, provides a summary of prior and current opinion with some historical context, and attempts to provide some modest guidance as to how to approach the various options to the patient's best advantage. Modalities to be addressed include indwelling electronic devices, the left ventricular assistance device, and extracorporeal mechanical oxygenation, and includes available outcome data as well as ethical analysis from a number of commentators. The expected further increase in technical sophistication of these devices is expected to render the various aspects of device deactivation more and more complex over the course of the next few years such that careful attention to and knowledge about this issue will continue to be more and more necessary.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine Learning Approaches for Automated Diagnosis of Cardiovascular Diseases: A Review of Electrocardiogram Data Applications. 心血管疾病自动诊断的机器学习方法:心电图数据应用综述》。
IF 2 4区 医学
Cardiology in Review Pub Date : 2024-09-12 DOI: 10.1097/CRD.0000000000000764
Abdelhakim Elmassaoudi, Samira Douzi, Mounia Abik
{"title":"Machine Learning Approaches for Automated Diagnosis of Cardiovascular Diseases: A Review of Electrocardiogram Data Applications.","authors":"Abdelhakim Elmassaoudi, Samira Douzi, Mounia Abik","doi":"10.1097/CRD.0000000000000764","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000764","url":null,"abstract":"<p><p>Cardiovascular diseases (CVDs) have been identified as the leading cause of mortality worldwide. Electrocardiogram (ECG) is a fundamental diagnostic tool used for the diagnosis and detection of these diseases. The new technological tools can help enhance the effectiveness of ECGs. Machine learning (ML) is widely acknowledged as a highly effective approach in the realm of computer-aided diagnostics. This article presents a review of the effectiveness of ML algorithms and deep-learning algorithms in diagnosing, identifying, and classifying CVDs using ECG data. The review identified relevant studies published in the 5 major databases: PubMed, Web of Science (WoS), Scopus, Springer, and IEEE Xplore; between 2021 and 2023, a total of 30 were chosen for the comprehensive quantitative and qualitative. The study demonstrated that different datasets are available online with data related to CVDs. The various ML techniques are employed for the purpose of classification. Based on our investigation, it has been observed that deep learning-based neural network algorithms, such as convolutional neural networks and deep neural networks, have demonstrated superior performance in the detection of entire record data. Furthermore, deep learning showcases its efficacy even when confronted with a scarcity of data. ML approaches utilizing ECG data exhibit a notable proficiency in the realm of diagnosis, hence holding the potential to mitigate the occurrence of disease-related consequences at advanced stages.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Influence of Pulmonary Arterial Hypertension In Pregnancy: A Review. 妊娠期肺动脉高压的影响:综述。
IF 2 4区 医学
Cardiology in Review Pub Date : 2024-09-10 DOI: 10.1097/CRD.0000000000000777
Jodie Renaud, Saam Foroshani, William H Frishman, Wilbert S Aronow
{"title":"The Influence of Pulmonary Arterial Hypertension In Pregnancy: A Review.","authors":"Jodie Renaud, Saam Foroshani, William H Frishman, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000777","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000777","url":null,"abstract":"<p><p>Pulmonary arterial hypertension (PAH) is a severe condition characterized by increased pulmonary vascular resistance and right ventricular failure. This review examines the intersection of PAH and pregnancy, highlighting the significant physiological, hemodynamic, and hormonal changes that exacerbate PAH during gestation. Pregnancy is contraindicated in PAH patients due to high maternal and fetal morbidity and mortality rates. However, some patients choose to continue their pregnancies, necessitating a comprehensive understanding of the implications and management strategies. Effective management of PAH in pregnant patients involves individualized treatment plans. Prepartum management focuses on optimizing therapy and monitoring hemodynamic status. Prostacyclin analogs and phosphodiesterase inhibitors are commonly used, though their safety profiles require further investigation. Intrapartum management prioritizes preventing right ventricular failure, utilizing therapies such as intravenous epoprostenol, inhaled iloprost, and inhaled nitric oxide. Managing PAH in pregnancy requires careful planning, continuous monitoring, and tailored therapeutic strategies to navigate the complex interplay of physiological changes and mitigate risks. Future research should focus on elucidating the pathophysiology of PAH during pregnancy and developing safer, more effective treatments to improve maternal and fetal outcomes.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac Complications of Multiple Myeloma Treatments. 多发性骨髓瘤治疗的心脏并发症。
IF 2 4区 医学
Cardiology in Review Pub Date : 2024-09-10 DOI: 10.1097/CRD.0000000000000787
Aatif Khurshid, William H Frishman, Wilbert S Aronow
{"title":"Cardiac Complications of Multiple Myeloma Treatments.","authors":"Aatif Khurshid, William H Frishman, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000787","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000787","url":null,"abstract":"<p><p>Multiple myeloma (MM) arises in plasma cells, a type of white blood cell. The cancerous plasma cells produce monoclonal immunoglobulins in the bone marrow. The extent of proliferation in the malignant state can manifest in many complications including osteopenia, osteolytic lesions, pathologic fractures, hypercalcemia, anemia, and kidney dysfunction. As is the case with the treatment of other malignancies, the research relating to the management of MM is dynamic and evolving. In this review, we aim to succinctly summarize and categorize the major treatment options of MM, including both new treatments and also older treatments that are now less frequently utilized, with a specific focus on the cardiotoxicity of these agents.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying the Role of Flow-Mediated Dilatation Assessment in Acute Coronary Syndromes: A Systematic Review. 确定急性冠状动脉综合征中血流介导的扩张评估的作用:系统性综述。
IF 2 4区 医学
Cardiology in Review Pub Date : 2024-09-10 DOI: 10.1097/CRD.0000000000000768
Georgios Zormpas, Aristi Boulmpou, Victoria Potoupni, Fotios Siskos, Nikoleta Chatzipapa, Nikolaos Fragakis, Michael Doumas, George Kassimis, Vassilios Vassilikos, Christodoulos E Papadopoulos
{"title":"Identifying the Role of Flow-Mediated Dilatation Assessment in Acute Coronary Syndromes: A Systematic Review.","authors":"Georgios Zormpas, Aristi Boulmpou, Victoria Potoupni, Fotios Siskos, Nikoleta Chatzipapa, Nikolaos Fragakis, Michael Doumas, George Kassimis, Vassilios Vassilikos, Christodoulos E Papadopoulos","doi":"10.1097/CRD.0000000000000768","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000768","url":null,"abstract":"<p><p>In the context of the global burden of cardiovascular disease, the development of novel, patient-targeted diagnostic and therapeutic strategies is of paramount importance. Acute coronary syndromes (ACS) comprise a subset of cardiovascular disease, with constantly increasing prevalence requiring urgent attention. Flow-mediated dilatation (FMD), a noninvasive method for the evaluation of endothelial function, has been previously implemented in patients with ACS. A systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was conducted in order to identify all relevant studies assessing the implementation of FMD among patients with ACS. Our review reflects an effort to present all available data regarding the role of FMD to date, a valuable noninvasive and easy accessible diagnostic tool, in the prognosis of patients with ACS. FMD evaluation in patients with ACS reveals a decline in values, indicative of the presence of endothelial function among this distinct patient group. FMD has also been used to assess the response to various treatments, as well as to predict major adverse cardiovascular events. Dynamic responses to interventions highlights its potential in the evolving field of interventional cardiology.</p>","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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