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Research Trends in the Relationship Between Orofacial Cleft and Cancer: A Bibliometric and Network Visualization Study. 口腔裂隙与癌症关系的研究趋势：文献计量与网络可视化研究》。
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-08-01 Epub Date: 2024-07-12 DOI: 10.1080/07357907.2024.2376279
Adriana Mendonça da Silva, Valéria Souza Freitas
{"title":"Research Trends in the Relationship Between Orofacial Cleft and Cancer: A Bibliometric and Network Visualization Study.","authors":"Adriana Mendonça da Silva, Valéria Souza Freitas","doi":"10.1080/07357907.2024.2376279","DOIUrl":"10.1080/07357907.2024.2376279","url":null,"abstract":"<p><strong>Objective: </strong>To use the bibliographic data of publications regarding the association between orofacial cleft (OC) and cancer to examine the implications of publication growth, co-citation, co-words, and authorship networks using bibliometric indicators and network visualization.</p><p><strong>Methods: </strong>Bibliometric study analyzed documents related to the association between OC and cancer. Data were obtained in October 2023 from the Scopus, Pubmed, Web of Science. The search strategy was developed, and data obtained were imported into R (\"bibliometrix\") for analysis. Results: 70 documents were found from 1977 to 2023. Most were journal articles (90.0%) designed as case-control studies (42.8%). American Journal of Epidemiology was the most relevant source. The most cited document was Frebourg T, et al. (2006). Vieira A, Martelli-Junior were the most cited author. Most authors were affiliated to Brazil (University of Montes Claros) and United States (University of Pittsburgh). Research in this thematic has included children and adults of both sexes. Research trend points to gastric cancer, leukemia and breast cancer as the most investigated cancers in association to OC.</p><p><strong>Conclusion: </strong>This bibliometric analysis helps fill research gaps regarding the knowledge of the relationship between OC and cancer, providing some clues for selecting future research in this topic.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metagenomic Analysis of Biliary Microbial Flora in Patients with Gallbladder Cancer or Gallstones-Associated Chronic Cholecystitis. 胆囊癌或胆结石相关慢性胆囊炎患者胆道微生物菌群的元基因组分析
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-07-01 Epub Date: 2024-06-07 DOI: 10.1080/07357907.2024.2361305
Ratnakar Shukla, Yasuo Tsuchiya, Anu Behari, Toshikazu Ikoma, Kazutoshi Nakamura, Vinay K Kapoor
{"title":"Metagenomic Analysis of Biliary Microbial Flora in Patients with Gallbladder Cancer or Gallstones-Associated Chronic Cholecystitis.","authors":"Ratnakar Shukla, Yasuo Tsuchiya, Anu Behari, Toshikazu Ikoma, Kazutoshi Nakamura, Vinay K Kapoor","doi":"10.1080/07357907.2024.2361305","DOIUrl":"10.1080/07357907.2024.2361305","url":null,"abstract":"<p><p>Biliary dysbiosis is associated with gallbladder cancer (GBC). We aimed to look for biliary bacteria specifically detected in GBC patients. We used 16S rRNA-based metagenomic analysis to elucidate biliary microbiota in 30 GBC and 30 gallstones-associated chronic cholecystitis patients. Relative abundance of five genera, <i>Streptococcus, Enterococcus</i>, <i>Halomonas</i>, <i>Escherichia</i> and <i>Caulobacter</i> was significantly associated with GBC. Of 15-species, 7 were detected significantly higher in GBC, <i>Streptococcus anginosus</i>, <i>Streptococcus constellatus</i>, <i>Streptococcus intermedius, Actinomyces bowdenii</i>, <i>Actinomyces israelii</i>, <i>Actinomyces gerencseriae</i>, and <i>Escherichia fergusonii</i> were biosafety level-2 infectious bacteria; other 8 species were biosafety level-1 bacteria. These bacterial species may be involved in pathogenesis of GBC.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141282997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fusobacterium Detected in Barrett's Esophagus and Esophageal Adenocarcinoma Tissues. 在巴雷特食管和食管腺癌组织中检测到镰刀菌
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-07-01 Epub Date: 2024-06-24 DOI: 10.1080/07357907.2024.2359980
Tomomitsu Tahara, Takuya Shijimaya, Jumpei Yamazaki, Sanshiro Kobayashi, Anna Horitani, Yasushi Matsumoto, Naohiro Nakamura, Takashi Okazaki, Yu Takahashi, Takashi Tomiyama, Yusuke Honzawa, Norimasa Fukata, Toshiro Fukui, Makoto Naganuma
{"title":"Fusobacterium Detected in Barrett's Esophagus and Esophageal Adenocarcinoma Tissues.","authors":"Tomomitsu Tahara, Takuya Shijimaya, Jumpei Yamazaki, Sanshiro Kobayashi, Anna Horitani, Yasushi Matsumoto, Naohiro Nakamura, Takashi Okazaki, Yu Takahashi, Takashi Tomiyama, Yusuke Honzawa, Norimasa Fukata, Toshiro Fukui, Makoto Naganuma","doi":"10.1080/07357907.2024.2359980","DOIUrl":"10.1080/07357907.2024.2359980","url":null,"abstract":"<p><p>We examined <i>Fusobacterium nucreatum</i> (<i>F. nucleatum</i>) and whole <i>Fusobacterium species</i> (<i>Pan-fusobacterium</i>) in non-neoplastic Barrett's esophagus (BE) from patients without cancer (<i>n</i> = 67; N group), with esophageal adenocarcinoma (EAC) (<i>n</i> = 27) and EAC tissue (<i>n</i> = 22). <i>F. nucleatum</i> was only detectable in 22.7% of EAC tissue. <i>Pan-fusobacterium</i> was enriched in EAC tissue and associated with aggressive clinicopathological features. Amount of <i>Pan-fusobacterium</i> in non-neoplastic BE was correlated with presence of hital hernia and telomere shortening. The result suggested potential association of <i>Fusobacterium species</i> in EAC and BE, featuring clinicpathological and molecular features.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141445691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Prophylactic Post-Chemotherapy G-CSF on the Relapse Rates in Patients with Acute Myeloid Leukemia: A Meta-Analysis. 化疗后预防性使用 G-CSF 对急性髓性白血病患者复发率的影响：一项 Meta 分析
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-07-01 Epub Date: 2024-06-26 DOI: 10.1080/07357907.2024.2352454
Mohammadreza Bordbar, Mahnaz Hosseini-Bensenjan, Mehrab Sayadi, Omidreza Zekavat, Shayan Bordbar, Farnoosh Nozari, Sezaneh Haghpanah
{"title":"The Impact of Prophylactic Post-Chemotherapy G-CSF on the Relapse Rates in Patients with Acute Myeloid Leukemia: A Meta-Analysis.","authors":"Mohammadreza Bordbar, Mahnaz Hosseini-Bensenjan, Mehrab Sayadi, Omidreza Zekavat, Shayan Bordbar, Farnoosh Nozari, Sezaneh Haghpanah","doi":"10.1080/07357907.2024.2352454","DOIUrl":"10.1080/07357907.2024.2352454","url":null,"abstract":"<p><p>This meta-analysis evaluated the impact of prophylactic post-chemotherapy granulocyte colony-stimulating factor (G-CSF) in patients with acute myeloid leukemia (AML). Overall, the relapse rate, overall survival, event-free survival, and mortality rate were similar in G-CSF (+) compared to G-CSF (-) patients. However, the relative risk (RR) of relapse was higher in children and in secondary AML patients who were treated with G-CSF compared to the G-CSF (-) group [RR, 95% confidence interval: 1.26, 1.04-1.52, and 1.12 (1.02-1.24)]. Treatment with post-chemotherapy G-CSF should be prescribed with caution in pediatric patients with AML and secondary AML as possibly increasing the relapse risk.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141449755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence in Cancer Clinical Research: II. Development and Validation of Clinical Prediction Models. 人工智能在癌症临床研究中的应用：II.临床预测模型的开发与验证。
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-07-01 Epub Date: 2024-05-22 DOI: 10.1080/07357907.2024.2354991
Gary H Lyman, Nicole M Kuderer
{"title":"Artificial Intelligence in Cancer Clinical Research: II. Development and Validation of Clinical Prediction Models.","authors":"Gary H Lyman, Nicole M Kuderer","doi":"10.1080/07357907.2024.2354991","DOIUrl":"10.1080/07357907.2024.2354991","url":null,"abstract":"","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141075438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elevated Vitamin B12, Risk of Cancer, and Mortality: A Systematic Review. 维生素 B12 升高、癌症风险和死亡率：系统回顾
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-07-01 Epub Date: 2024-07-02 DOI: 10.1080/07357907.2024.2366907
Sandra B Amado-Garzon, Luisana Molina-Pimienta, Andrea Vejarano-Pombo, Mariana Vélez-Bonilla, Jaime Moreno-Chaparro, Adriana Buitrago-Lopez
{"title":"Elevated Vitamin B12, Risk of Cancer, and Mortality: A Systematic Review.","authors":"Sandra B Amado-Garzon, Luisana Molina-Pimienta, Andrea Vejarano-Pombo, Mariana Vélez-Bonilla, Jaime Moreno-Chaparro, Adriana Buitrago-Lopez","doi":"10.1080/07357907.2024.2366907","DOIUrl":"10.1080/07357907.2024.2366907","url":null,"abstract":"<p><p>Vitamin B12 (B12) is a molecule involved in several biological. Abnormally high levels are frequently found, but their causes can be multiple, and consequences have not been clearly elucidated. The objective of this review was to summarize the current evidence on the associations of elevated B12 and the development of cancer, and all-cause mortality in adults. Six references looking at mortality and seven looking at cancer risk were included. The evidence suggests an association between elevated B12 with a higher risk of cancer, with risk ratios ranging 1,88 to 5,9. There was less consistent evidence linking vitamin B12 and mortality.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141490966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Effects of Sarcopenia on Patients with Bladder Cancer: A Systematic Review and Meta-Analysis. 肌肉疏松症对膀胱癌患者预后的影响：系统回顾与元分析》。
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-07-01 Epub Date: 2024-06-18 DOI: 10.1080/07357907.2024.2363879
Yinghan Zeng, Chengna Cai, Nafen Pan
{"title":"Prognostic Effects of Sarcopenia on Patients with Bladder Cancer: A Systematic Review and Meta-Analysis.","authors":"Yinghan Zeng, Chengna Cai, Nafen Pan","doi":"10.1080/07357907.2024.2363879","DOIUrl":"10.1080/07357907.2024.2363879","url":null,"abstract":"<p><p>Sarcopenia can negatively impact the survival of cancer patients. This study intends to delve into the correlation of sarcopenia with survival and complications in patients with bladder cancer (BC) after surgery. Web of Science, Cochrane Library, Embase, and PubMed databases were retrieved up to April 7, 2023, to collect studies on the impact of sarcopenia on the prognosis of adults with BC. Primary outcomes encompassed overall survival (OS), cancer-specific survival (CSS), and recurrence-free survival (RFS). The secondary outcome consisted of postoperative complications. A meta-analysis was conducted using Stata. Forest plots and summary effect models were employed to present the results. The quality of eligible studies was assessed using the Newcastle-Ottawa Scale (NOS). Initially, 1713 studies were identified through searches across four databases, and 26 studies were ultimately included in the analysis. Sarcopenia was significantly associated with OS (HR:1.62; 95% CI: 1.43-1.83; <i>P</i> < 0.001, <i>I</i><sup>2</sup> = 0.9%), CSS (HR: 1.81, 95% CI: 1.52-2.15, <i>P</i> < 0.001, <i>I</i><sup>2</sup> = 0.0%), and RFS (HR: 1.76, 95% CI: 1.21-2.56, <i>P</i> = 0.003, <i>I</i><sup>2</sup> = 0.0%) in BC patients. Subgroup analyses revealed that sarcopenia is strongly linked to prognosis and postoperative complications in BC patients.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141417943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Bioinformatic Analysis of Gut Microbiota Related with Immune Cell Infiltration in Colorectal Cancer. 结直肠癌免疫细胞浸润相关肠道微生物群的生物信息学分析
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-07-01 Epub Date: 2024-06-21 DOI: 10.1080/07357907.2024.2368233
Dan Liu, Jiang Zhou, Qiong Fu, Yuanzhu Zhao, Panpan Wang, Yang Zheng, Meihong Cui, Heng Zhang
{"title":"A Bioinformatic Analysis of Gut Microbiota Related with Immune Cell Infiltration in Colorectal Cancer.","authors":"Dan Liu, Jiang Zhou, Qiong Fu, Yuanzhu Zhao, Panpan Wang, Yang Zheng, Meihong Cui, Heng Zhang","doi":"10.1080/07357907.2024.2368233","DOIUrl":"10.1080/07357907.2024.2368233","url":null,"abstract":"<p><strong>Objective: </strong>The composition of microbiota which correlates with infiltrating immune cells and clinical signatures is not clarified in CRC.</p><p><strong>Methods: </strong>We applied 4 kinds of bioinformatic tools GSVA (version: 1.42.0), ESTIMATE (version: 1.0.13), CIBERSORT (version: 2.0), and immune-related genes.</p><p><strong>Results: </strong>We found that a total of 8 types of microbiotas appeared in the three immune correlation analyses. Among these microbiotas, significant enrichments in relative abundances associated with immune cell infiltration can be found for the dominant phyla Proteobacteria, Firmicutes, and Actinobacteria. Moreover, there existed correlations between some of the 8 microbiotas and clinical-related indicators.</p><p><strong>Conclusion: </strong>We identified some novel microbiotas involved in immune regulation in CRC.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141436399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gustative Roussy Immune Score is a Predictor for Major Pathological Response in Rectal Cancer: A Result from the Preoperative Intraarterial Chemoembolization Combined with Radiotherapy (PCAR) Study. Gustative Roussy 免疫评分是直肠癌主要病理反应的预测指标：术前动脉内化疗栓塞联合放疗（PCAR）研究结果。
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-07-01 Epub Date: 2024-07-05 DOI: 10.1080/07357907.2024.2366912
Wei-Na Yang, Xue-Mei Li, Chao-Fan Li, Chuan Chen, Yan Feng, Nan Dai, Yu-Xin Yang, Meng-Xia Li, Chun-Xue Li, Cheng-Yuan Qian, Dong Wang, He Xiao, Jia-Min Luo
{"title":"Gustative Roussy Immune Score is a Predictor for Major Pathological Response in Rectal Cancer: A Result from the Preoperative Intraarterial Chemoembolization Combined with Radiotherapy (PCAR) Study.","authors":"Wei-Na Yang, Xue-Mei Li, Chao-Fan Li, Chuan Chen, Yan Feng, Nan Dai, Yu-Xin Yang, Meng-Xia Li, Chun-Xue Li, Cheng-Yuan Qian, Dong Wang, He Xiao, Jia-Min Luo","doi":"10.1080/07357907.2024.2366912","DOIUrl":"10.1080/07357907.2024.2366912","url":null,"abstract":"<p><p>Despite the emergence of various treatment strategies for rectal cancer based on neoadjuvant chemoradiotherapy, there is currently a lack of reliable biomarkers to determine which patients will respond well to neoadjuvant chemoradiotherapy. Through collecting hematological and biochemical parameters data of patients prior to receiving neoadjuvant chemoradiotherapy, we evaluated the predictive value of systemic inflammatory indices for pathological response and prognosis in rectal cancer patients. We found that baseline GRIm-Score was an independent predictor for MPR in rectal cancer patients. However, no association was observed between several commonly systemic inflammation indices and long-term outcome.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141533682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimization of Epigenetic Modifier Drug Combination for Synergistic Effect against Glioblastoma Multiform Cancer Cell Lines 优化表观遗传修饰剂药物组合，实现对多形性胶质母细胞瘤癌症细胞株的协同作用
IF 2.4 4区 医学
Cancer Investigation Pub Date : 2024-05-02 DOI: 10.1080/07357907.2024.2345183
Morvarid Soleiman, Mehrnoosh Fathi-Roudsari, Khosro Khajeh, Amir Maghsoudi
{"title":"Optimization of Epigenetic Modifier Drug Combination for Synergistic Effect against Glioblastoma Multiform Cancer Cell Lines","authors":"Morvarid Soleiman, Mehrnoosh Fathi-Roudsari, Khosro Khajeh, Amir Maghsoudi","doi":"10.1080/07357907.2024.2345183","DOIUrl":"https://doi.org/10.1080/07357907.2024.2345183","url":null,"abstract":"Glioblastoma multiforme (GBM), is a frequent class of malignant brain tumors. Epigenetic therapy, especially with synergistic combinations is highly paid attention for aggressive solid tumors like ...","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140829478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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