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Erratum regarding previously published article 关于以前发表的文章的勘误
Oral Oncology Reports Pub Date : 2024-12-01 DOI: 10.1016/j.oor.2023.100138
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引用次数: 0
Erratum regarding previously published article 关于以前发表的文章的勘误
Oral Oncology Reports Pub Date : 2024-12-01 DOI: 10.1016/j.oor.2023.100137
{"title":"Erratum regarding previously published article","authors":"","doi":"10.1016/j.oor.2023.100137","DOIUrl":"10.1016/j.oor.2023.100137","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"12 ","pages":"Article 100137"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143154347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing PD-L1/PD-1 therapies: Immune checkpoint inhibitors in nasopharyngeal carcinoma 优化PD-L1/PD-1疗法：鼻咽癌免疫检查点抑制剂
Oral Oncology Reports Pub Date : 2024-12-01 DOI: 10.1016/j.oor.2024.100675
Madhan Krishnan, Gayathri Sekar
{"title":"Optimizing PD-L1/PD-1 therapies: Immune checkpoint inhibitors in nasopharyngeal carcinoma","authors":"Madhan Krishnan, Gayathri Sekar","doi":"10.1016/j.oor.2024.100675","DOIUrl":"10.1016/j.oor.2024.100675","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"12 ","pages":"Article 100675"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143154344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computational biology approach to predict molecular mechanism in cancer 计算生物学方法预测癌症分子机制
Oral Oncology Reports Pub Date : 2024-12-01 DOI: 10.1016/j.oor.2024.100651
Ansari Vikhar Danish Ahmad, Subur W. Khan, Qazi Yasar, Mohd Sayeed Shaikh, Mohd Mukhtar Khan
{"title":"Computational biology approach to predict molecular mechanism in cancer","authors":"Ansari Vikhar Danish Ahmad,&nbsp;Subur W. Khan,&nbsp;Qazi Yasar,&nbsp;Mohd Sayeed Shaikh,&nbsp;Mohd Mukhtar Khan","doi":"10.1016/j.oor.2024.100651","DOIUrl":"10.1016/j.oor.2024.100651","url":null,"abstract":"<div><div>The field of biology offers a complete structure for studying intricate molecular interactions and the strength of bonding between molecules but with an emphasis on developing treatments and discovering markers in medicine research that hold promise for targeting specific diseases like cancer subtypes effectively by pinpointing crucial signals and pathways crucial for tumor development growth, alongside network analysis as a potent tool to foresee how small molecules interact with proteins linked to cancer and determine promising new treatments. This methodical strategy enables the evaluation of potential medications by assessing their capacity to bind effectively to cancer causing targets for enhanced treatment accuracy.\" Additionally integrating machine learning methods with multi dataset analyses greatly enhances the thorough examination of cancer associated molecular connections ultimately streamlining drug development and biomarker discovery. This underscores the importance of molecular docking in forecasting interactions, between drugs and their targets within the realm of cancer bioinformatics.</div></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"12 ","pages":"Article 100651"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143154345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum regarding previously published article 关于以前发表的文章的勘误
Oral Oncology Reports Pub Date : 2024-12-01 DOI: 10.1016/j.oor.2023.100136
{"title":"Erratum regarding previously published article","authors":"","doi":"10.1016/j.oor.2023.100136","DOIUrl":"10.1016/j.oor.2023.100136","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"12 ","pages":"Article 100136"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143154348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HPV status and staging in oropharyngeal carcinoma: A review of recent AJCC/UICC revisions 口咽癌的HPV状态和分期：近期AJCC/UICC修订的回顾
Oral Oncology Reports Pub Date : 2024-11-29 DOI: 10.1016/j.oor.2024.100694
Madhan Krishnan , Sharan Basappa , Shyamaladevi Babu , Sandhya P
{"title":"HPV status and staging in oropharyngeal carcinoma: A review of recent AJCC/UICC revisions","authors":"Madhan Krishnan ,&nbsp;Sharan Basappa ,&nbsp;Shyamaladevi Babu ,&nbsp;Sandhya P","doi":"10.1016/j.oor.2024.100694","DOIUrl":"10.1016/j.oor.2024.100694","url":null,"abstract":"<div><div>The incidence of oropharyngeal carcinoma (OPC) has been rising, particularly among HPV-positive patients, prompting a reevaluation of clinical staging practices. Recent revisions to the AJCC/UICC staging systems have recognized the distinct biological behavior associated with HPV-positive tumors, highlighting the necessity for tailored staging criteria that better reflect their unique prognostic characteristics. This review discusses the implications of HPV status on the clinical staging of oropharyngeal carcinoma, focusing on how these revisions influence prognosis and treatment strategies. The differential outcomes observed between HPV-positive and HPV-negative patients necessitate a more nuanced approach to management, advocating for personalized treatment plans that consider the specific tumor biology. Additionally, we explore the ongoing research efforts aimed at further refining staging criteria, including the identification of relevant biomarkers and the integration of advanced imaging techniques. As our understanding of HPV's role in cancer biology continues to evolve, it is imperative that our approaches to staging and management adapt accordingly. Ultimately, these revisions and the accompanying research will contribute to improved patient outcomes and more effective therapeutic interventions in the increasingly prevalent landscape of oropharyngeal carcinoma.</div></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"13 ","pages":"Article 100694"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of cancer associated fibroblasts amongst different histological variants of oral squamous cell carcinoma 口腔鳞状细胞癌不同组织学变异中癌相关成纤维细胞的评估
Oral Oncology Reports Pub Date : 2024-11-29 DOI: 10.1016/j.oor.2024.100696
Reshma Poothakulath Krishnan , Deepak Pandiar , Pratibha Ramani , Neha Kannan , Selvaraj Jayaraman
{"title":"Assessment of cancer associated fibroblasts amongst different histological variants of oral squamous cell carcinoma","authors":"Reshma Poothakulath Krishnan ,&nbsp;Deepak Pandiar ,&nbsp;Pratibha Ramani ,&nbsp;Neha Kannan ,&nbsp;Selvaraj Jayaraman","doi":"10.1016/j.oor.2024.100696","DOIUrl":"10.1016/j.oor.2024.100696","url":null,"abstract":"<div><h3>Background</h3><div>Cancer associated fibroblasts are heterogenous activated fibroblasts that form the central component of the tumor microenvironment. These cells influence the behavior of the tumor by activating various signaling pathways and initiating epithelial mesenchymal transition. CAFs have been reported in oral squamous cell carcinomas (OSCC), however, very few studies have evaluated the role of CAFs in different variants of OSCC. The aim of this study was to compare the role of CAFs in conventional OSCC and different variants of OSCCs.</div></div><div><h3>Materials and methods</h3><div>Eight each of well differentiated, moderately differentiated and poorly differentiated OSCC, 5 each of verrucous carcinoma and verrucous carcinoma turning into OSCC, three each of spindle cell carcinoma, basaloid OSCC and OSCC with clear cell differentiation and 2 cases of papillary OSCC were retrieved, and immunohistochemistry was performed with α-SMA to identify and evaluate the CAFs. Kaplan Meier analysis was carried out to evaluate the overall survival of the patients.</div></div><div><h3>Results</h3><div>Progressive increase in the CAF immunostaining was noted from papillary squamous cell carcinoma [mean - 1] to basaloid squamous cell carcinoma [1.6 ± 0.5] to spindle cell carcinoma and squamous cell carcinoma with clear cell changes [2.6 ± 0.5] (p = 0.00 - statistically significant). Patients with abundant CAF expression showed lesser survival rate when compared to patients with scanty or focal CAF immunohistochemical staining.</div></div><div><h3>Conclusion</h3><div>Increased CAF immunoexpression was noted in PDSCCs, VCs turning into SCC, OSCC with clear cell changes and spindle cell carcinoma. This highlights the aggressive nature of these tumors. Screening these tumor for the presence of CAFs will help in treatment planning and will aid in treatment planning and survival analysis.</div></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"13 ","pages":"Article 100696"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A fight against cancer with advancement of Schiff base metal complexes: Future prospects 希夫贱金属配合物与癌症的对抗：未来展望
Oral Oncology Reports Pub Date : 2024-11-26 DOI: 10.1016/j.oor.2024.100692
Monika Tyagi, Monika Dubey
{"title":"A fight against cancer with advancement of Schiff base metal complexes: Future prospects","authors":"Monika Tyagi,&nbsp;Monika Dubey","doi":"10.1016/j.oor.2024.100692","DOIUrl":"10.1016/j.oor.2024.100692","url":null,"abstract":"<div><div>Cancer remains a formidable global health challenge, demanding continuous efforts to develop innovative and effective therapeutic strategies. Recently, Schiff base metal complexes (SBMCs) have attracted considerable interest as potential anticancer agents because of their varied chemical properties and promising biological activities. This comprehensive review delves the latest advancements in the use of SBMCs in cancer therapy. It covers the synthesis and characterization of these complexes, their mechanisms of action, and their potential advantages over conventional chemotherapy. Furthermore, the review discusses challenges and future perspectives in utilizing SBMCs to enhance cancer treatment outcomes, paving the way for a more targeted and personalized approach in the fight against cancer.</div></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"13 ","pages":"Article 100692"},"PeriodicalIF":0.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of Bone Ring Technique (BRT) for 3D reconstruction in the anterior aesthetic zone after tumor surgery 骨环技术（BRT）在肿瘤术后前美学区三维重建中的应用
Oral Oncology Reports Pub Date : 2024-11-22 DOI: 10.1016/j.oor.2024.100684
Yan-Sheng Zeng , Peng-Yu Lai , Shan Shen
{"title":"Application of Bone Ring Technique (BRT) for 3D reconstruction in the anterior aesthetic zone after tumor surgery","authors":"Yan-Sheng Zeng ,&nbsp;Peng-Yu Lai ,&nbsp;Shan Shen","doi":"10.1016/j.oor.2024.100684","DOIUrl":"10.1016/j.oor.2024.100684","url":null,"abstract":"<div><div>Surgery and periodontitis contribute to alveolar bone loss, resulting in increased tooth mobility. This is particularly evident post-tumor surgery, where larger bone defects are commonly encountered. Adequate bone mass is crucial for successful implant restoration in missing teeth. Conventional repair methods are unable to meet patients' functional and aesthetic expectations, while the loss of alveolar bone further compromises the initial stability of the implant. In the face of these challenges, Bone Ring Technique (BRT) demonstrates significant advantages. We conducted 3D reconstruction of the anterior aesthetic zone in a patient with maxillary bone defects following excision of maxillary odontogenic fibroma using BRT, resulting in satisfactory implant stability. This suggests the potential of BRT as a promising bone grafting technique.</div></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"13 ","pages":"Article 100684"},"PeriodicalIF":0.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resection of a left carotid body tumor in a young female patient: A case report 年轻女性患者左侧颈动脉体肿瘤切除术1例
Oral Oncology Reports Pub Date : 2024-11-22 DOI: 10.1016/j.oor.2024.100691
Anish P. Kamat , Abhishek Shukla , Mandar Deshpande
{"title":"Resection of a left carotid body tumor in a young female patient: A case report","authors":"Anish P. Kamat ,&nbsp;Abhishek Shukla ,&nbsp;Mandar Deshpande","doi":"10.1016/j.oor.2024.100691","DOIUrl":"10.1016/j.oor.2024.100691","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"13 ","pages":"Article 100691"},"PeriodicalIF":0.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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