Oral Oncology Reports最新文献_第9页

Comment on, ‘Predictors of anxiety and depression in patients with oral cancer undergoing radical resection with reconstructive surgery’ 就 "接受根治性切除和重建手术的口腔癌患者焦虑和抑郁的预测因素 "发表评论

Oral Oncology Reports Pub Date : 2024-07-04 DOI: 10.1016/j.oor.2024.100573

Raghul Murugan

引用次数: 0

A systematic review of contemporary phase I trials in patients with recurrent/metastatic head and neck cancer 针对复发/转移性头颈癌患者的当代 I 期试验系统回顾

Oral Oncology Reports Pub Date : 2024-07-04 DOI: 10.1016/j.oor.2024.100588

V.G. Espeli , A. Gomez , P. Balermpas , G. Treglia , A. Stathis

{"title":"A systematic review of contemporary phase I trials in patients with recurrent/metastatic head and neck cancer","authors":"V.G. Espeli , A. Gomez , P. Balermpas , G. Treglia , A. Stathis","doi":"10.1016/j.oor.2024.100588","DOIUrl":"10.1016/j.oor.2024.100588","url":null,"abstract":"<div><p>We performed a systematic review of phase I trials specifically conducted for patients with head and neck squamous cell carcinoma published between January 1, 2008 and August 31, 2023. PubMed and Cochrane Library databases were searched using a combination of terms: “((head and neck) OR (head & neck)) AND ((cancer*) OR (tumor*) OR (tumour*) OR (neoplasm*) OR (carcinoma*) OR (malignan*)) AND ((phase 1) OR (phase I))\"to identify phase I dose-finding trials including a majority of lymphoma patients.</p><p>Eighty-five trials (H&N patients N = 1714) were included. Among them, 53 trials complying with inclusion/exclusion criteria and were included in the current analysis: 32 (60 %) enrolled only patients with head and neck cancer, while 21 (40 %) included also patients with other solid tumors.</p><p>The median rate of grade 3-4 adverse events was 41 %. With regards to clinical activity, the median response rate (RR) was 16 %, which is in line with the usually reported rate for phase I trials enrolling unselected populations of patients with solid tumors.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004345/pdfft?md5=713aab26e897b0903c551dc4ebe6fd36&pid=1-s2.0-S2772906024004345-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141692856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to editor: Comment on “salivary exosomes as biomarkers for early diagnosis of oral squamous cell carcinoma” 致编辑的信关于 "唾液外泌体作为口腔鳞状细胞癌早期诊断的生物标记物 "的评论

Oral Oncology Reports Pub Date : 2024-07-04 DOI: 10.1016/j.oor.2024.100585

Gokul Sudhakaran

引用次数: 0

Letter to editor: Comment on “Quantitative and qualitative features of tissue biopsy for successful diagnosis of oral cancer” 致编辑的信关于 "成功诊断口腔癌的组织活检定量和定性特征 "的评论

Oral Oncology Reports Pub Date : 2024-07-04 DOI: 10.1016/j.oor.2024.100594

Gokul Sudhakaran

引用次数: 0

Letter to editor: Comment on “identification of a potential prognostic panel of biomarkers for stratification of head and neck squamous cell carcinoma based on HPV status and TP53 mutational status” 致编辑的信：关于 "基于HPV状态和TP53突变状态的头颈部鳞状细胞癌分层生物标志物潜在预后面板的鉴定 "的评论

Oral Oncology Reports Pub Date : 2024-07-04 DOI: 10.1016/j.oor.2024.100597

Gokul Sudhakaran

引用次数: 0

Financial toxicity in head and neck cancer care: Current issues and future directions 头颈部癌症治疗中的财务毒性：当前问题与未来方向

Oral Oncology Reports Pub Date : 2024-07-04 DOI: 10.1016/j.oor.2024.100580

Amol S. Dhane

引用次数: 0

Advancements in immunotherapy: Transforming the landscape of oral cancer treatment 免疫疗法的进展：改变口腔癌治疗的格局

Oral Oncology Reports Pub Date : 2024-07-04 DOI: 10.1016/j.oor.2024.100570

Madhan Krishnan, Shyamaladevi Babu

引用次数: 0

Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature review 口腔潜在恶性和恶性疣状乳头状瘤病变的临床病理分析--文献综述

Oral Oncology Reports Pub Date : 2024-07-04 DOI: 10.1016/j.oor.2024.100587

Baishakhi Modak (Final year postgraduate), Spoorti Kulkarni (Associate professor)

{"title":"Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature review","authors":"Baishakhi Modak (Final year postgraduate), Spoorti Kulkarni (Associate professor)","doi":"10.1016/j.oor.2024.100587","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100587","url":null,"abstract":"<div><h3>Aims</h3><p>This review article aims to provide an in-depth analysis of potentially malignant and malignant verrucopapillary lesions, including their etiology, clinical and histological features, differential diagnosis, and immunohistochemical analysis.</p></div><div><h3>Background</h3><p>The word verrucopapillary lesions (VPL) refers to a variety of lesions in the oral region, ranging from benign to completely malignant tumors. They cause surface changes that can be seen as ulcerative, vesiculobullous, or papillary/papular/polypoid lesions, altering the usual morphology and stability of the mucosa.</p></div><div><h3>Review results</h3><p>The clinical, histopathological and immunohistochemical characteristics of oral verrucopapillary lesions may help in their accurate diagnosis.</p></div><div><h3>Clinical significance</h3><p>Verrucous and papillary lesions of the oral cavity are diagnostically challenging because of similar clinical presentation. The current understanding of potentially malignant VPLs is perplexing due to numerous terminologies. Many of the controversies in these entities are due to the lack of consensus on the disease characteristics and management.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004333/pdfft?md5=0ff2fa02af82b57f79282696ac752549&pid=1-s2.0-S2772906024004333-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141607661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the editor, “Inhibition of anti-tumour reactivity of immune cells in the salivary gland cancer: A proteomic approach.” 致编辑的信，"唾液腺癌中免疫细胞抗肿瘤反应性的抑制：蛋白质组学方法"。

Oral Oncology Reports Pub Date : 2024-07-04 DOI: 10.1016/j.oor.2024.100581

Geetha Shanmugam

引用次数: 0

Evaluating ddPCR and RT-qPCR methods for PIK3CA mutation detection in head and neck cancer via precision oncology 评估通过精准肿瘤学检测头颈癌中 PIK3CA 突变的 ddPCR 和 RT-qPCR 方法

Oral Oncology Reports Pub Date : 2024-07-03 DOI: 10.1016/j.oor.2024.100576

Akankshya Dash, Chinnasamy Ragavendran

引用次数: 0