Oral Oncology Reports最新文献

{"title":"Letter to the editor, “Predictors of anxiety and depression in patients with oral cancer are undergoing radical resection with reconstructive surgery”","authors":"Geetha Shanmugam","doi":"10.1016/j.oor.2024.100572","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100572","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004187/pdfft?md5=32ac270f58e0f54f047a05ea35b9711c&pid=1-s2.0-S2772906024004187-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141541467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing artificial intelligence for predictive modelling in oral oncology: Opportunities, challenges, and clinical Perspectives","authors":"Vishnu Priya Veeraraghavan ,&nbsp;Shikhar Daniel ,&nbsp;Arun Kumar Dasari ,&nbsp;Kaladhar Reddy Aileni ,&nbsp;Chaitra patil ,&nbsp;Santosh R. Patil","doi":"10.1016/j.oor.2024.100591","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100591","url":null,"abstract":"<div><p>Artificial intelligence (AI) has emerged as a promising tool in oral oncology, particularly in the field of prediction. This review provides a comprehensive outlook on the role of AI in predicting oral cancer, covering key aspects such as data collection and preprocessing, machine learning techniques, performance evaluation and validation, challenges, future prospects, and implications for clinical practice. Various AI algorithms, including supervised learning, unsupervised learning, and deep learning approaches, have been discussed in the context of oral cancer prediction. Additionally, challenges such as interpretability, data accessibility, regulatory compliance, and legal implications are addressed along with future research directions and the potential impact of AI on oral oncology care.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004370/pdfft?md5=fcb418c11ec3fe96695431c518f5d01d&pid=1-s2.0-S2772906024004370-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141541465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral verrucous hyperplasia – A literature review","authors":"R. Santhosh Kumar,&nbsp;Divya Bose,&nbsp;Thayalan Dineshkumar,&nbsp;M. Harinisubasri,&nbsp;Rajkumar Krishnan,&nbsp;Rameshkumar Annasamy","doi":"10.1016/j.oor.2024.100590","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100590","url":null,"abstract":"<div><h3>Background</h3><p>Oral verrucous hyperplasia (OVH) is considered an irreversible precancerous lesion that has the potential to develop into oral verrucous carcinoma. It might be challenging to diagnose these lesions both clinically and histopathologically. Hence the current review aimed to analyze the clinical and histopathological features of OVH and to determine their prognosis.</p></div><div><h3>Materials and methods</h3><p>An electronic literature search was done in PubMed, and Google Scholar databases for identifying articles published between 2000 and 2023. Case reports or series or original articles published in the English language reporting information on oral verrucous hyperplasia were included in this review.</p></div><div><h3>Results</h3><p>15 articles were included of which 3 were case series, 10 were case reports, 1 was a retrospective study and 1 was a cohort study.</p></div><div><h3>Conclusion</h3><p>OVH appears clinically as a verrucous plaque or mass. It shows a predilection for middle-aged and older adults, with male predominance. Patients with OVH should be treated similar to oral verrucous carcinoma and should be continuously monitored for disease recurrence and malignant transformation.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004369/pdfft?md5=6dd3bc6556b589d5ef26a270f0648950&pid=1-s2.0-S2772906024004369-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141543745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging targeted therapies in oral oncology: Focus on EGFR inhibition","authors":"Vishnu Priya Veeraraghavan ,&nbsp;Shikhar Daniel ,&nbsp;Arun Kumar Dasari ,&nbsp;Kaladhar Reddy Aileni ,&nbsp;Chaitra patil ,&nbsp;Santosh R. Patil","doi":"10.1016/j.oor.2024.100592","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100592","url":null,"abstract":"<div><p>This comprehensive study explored the role of epidermal growth factor receptor (EGFR)-targeted therapies in oral cancer, focusing on emerging strategies, challenges, and future directions. The EGFR signalling pathway plays a critical role in the development and progression of oral cancer, making it an attractive therapeutic target. Small-molecule tyrosine kinase inhibitors (TKIs) and monoclonal antibodies (mAbs) targeting EGFR have shown promise in preclinical studies and clinical trials. However, challenges, such as the development of resistance mechanisms and treatment-related toxicities, pose obstacles to their clinical utility. Future directions in EGFR-targeted therapy include the exploration of combination therapies and the identification of predictive biomarkers to optimize treatment strategies and improve patient outcomes in oral cancer.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004382/pdfft?md5=63a50b633cdae7b0bae7216702772a46&pid=1-s2.0-S2772906024004382-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141541443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of cigarette taxes and prices in Latin America tobacco smoking prevalence: A systematic review","authors":"Ana Leticia Mores ,&nbsp;Maria Eduarda Pérez-de-Oliveira ,&nbsp;Ana Gabriela Costa Normando ,&nbsp;Leticia Rodrigues-Oliveira ,&nbsp;Gustavo Nader Marta ,&nbsp;Renata Ferrarotto ,&nbsp;Thaís Bianca Brandão ,&nbsp;Alan Roger Santos-Silva ,&nbsp;Ana Carolina Prado-Ribeiro","doi":"10.1016/j.oor.2024.100574","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100574","url":null,"abstract":"<div><p>The present systematic review (SR) aimed to analyze the impact of cigarette taxes and prices on the prevalence of tobacco smoking in Latin America countries. The methods of this SR were previously established and registered in PROSPERO (CRD42022319407) and was reported according to the PRISMA checklist. The searches were made in 5 databases (PubMed/MEDLINE, Scopus, Embase, Web of Science and LILACS) in addition to the grey literature, without limitation of year, and published in English, Spanish or Portuguese. Studies which analyzed cigarette taxes and prices on tobacco smoking prevalence in Latin America were eligible for inclusion. The study selection was conducted in two phases by two independently reviewers. Seven observational studies conducted in Brazil, Mexico and Colombia were included in the qualitative analysis. The risk of bias (RoB) of each study was assessed using the Joanna Briggs Institute checklist. All studies found that an increase in excise taxes of cigarette led to an increase in the retail price. Four studies (57.1 %) reported that increasing cigarette taxes and prices was effective to decrease the prevalence of tobacco smoking. The included studies were graded as having a low (57.1 %) or moderate (42.8 %) RoB. The use of cigarette taxes and prices measures are effective tools to reduce the prevalence of tobacco smoking. However, it is vital the development of further research on this topic in other countries of Latin America since the included studies were performed only in Brazil, Colombia and Mexico.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004205/pdfft?md5=d4923791aaba1e4d5bb0d51f77228bf2&pid=1-s2.0-S2772906024004205-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141541466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor, “exploring salivary gene expression clusters: A bioinformatics approach for advanced diagnosis and prognosis in head and neck squamous cell carcinoma”","authors":"Geetha Shanmugam","doi":"10.1016/j.oor.2024.100567","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100567","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004138/pdfft?md5=2a6715a972edfc59fab245b0ce8d380b&pid=1-s2.0-S2772906024004138-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is narrow band imaging accurate to differentiate between high-risk and low-risk vocal fold leukoplakia? A systematic review and meta-analysis","authors":"Mina Sarabi Jamab ,&nbsp;Arezoo Aghakouchakzadeh ,&nbsp;Seied Omid Keyhan ,&nbsp;Hosein Rafiemanesh ,&nbsp;Ahmadreza Mirzaei ,&nbsp;Mina Teimouri Badeleh Dareh","doi":"10.1016/j.oor.2024.100560","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100560","url":null,"abstract":"<div><p>Vocal fold leukoplakia (VFL) is a pre-cancerous lesion that its management is still a therapeutic dilemma due to the need for timely diagnosis of its nature. Narrow band imaging (NBI) seemed to be beneficial to evaluate VFL. The present review aimed to explore the diagnostic accuracy of NBI in differentiating between low-risk and high-risk VFLs.</p><p>Thirteen studies met the criteria of this systematic review and 11 of them were included in meta-analysis. The pooled sensitivity and specificity of NBI were 78.02 % (95 % CI: 71.64 %–83.31 %) and 93.70 % (95 % CI: 89.23 %–39.39 %), respectively. Ni 2011 had higher diagnostic accuracy among three main NBI classifications.</p><p>In conclusion, NBI appeared to be an accurate and useful endoscopic method for evaluating VFL lesions.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004060/pdfft?md5=bcb722a694a87f4ee16af628341e3804&pid=1-s2.0-S2772906024004060-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macrophages infiltration and oral potentially malignant disorders: A systematic review and meta-analysis","authors":"Lara Krusser Feltraco ,&nbsp;Julia Rodrigues Fernandes ,&nbsp;Leonardo Francisco Diel ,&nbsp;Leonardo da Silva Bittencourt ,&nbsp;Lisiane Bernardi ,&nbsp;Marcelo Lazzaron Lamers","doi":"10.1016/j.oor.2024.100559","DOIUrl":"10.1016/j.oor.2024.100559","url":null,"abstract":"<div><h3>Objective</h3><p>Oral potentially malignant disorders often show a chronic inflammatory profile resulting in cellular changes at epithelial and stromal components. Since oral squamous cell carcinoma shows an association between macrophages and a worse prognosis, we hypothesize that macrophages could also be involved in the evolution of oral potentially malignant disorders into oral squamous cell carcinoma. Herein, we conducted a systematic review with meta-analysis in order to assess the role of macrophages in oral potentially malignant disorders severity and prognosis.</p></div><div><h3>Design</h3><p>a literature search was performed encompassing all Clinical studies assessing the presence of macrophages in dysplastic and non-dysplastic tissues in relation to the prognosis of potentially malignant disorders, without restrictions on year, language, or publication status (in press).</p></div><div><h3>Results</h3><p>Twenty-one articles fully attended the inclusion criteria, which included oral lichen planus (9/21 articles), oral leukoplakia/dysplasia (11/21 articles), oral submucous fibrosis (2/21 articles) and chronic graft-versus-host disease (1/21 articles, n = 12 patients) lesions. Most of the articles indicated that pan macrophages (CD68⁺) marker and the pro-tumoral M2 macrophage marker (CD163⁺) were distributed in the connective tissue and subepithelial compartment, with an increase in the number according to the pathological grade (mild, moderated or severe) and area of oral potentially malignant disorders (i.e epithelial or subepithelial layer).</p></div><div><h3>Conclusions</h3><p>This systematic review indicates that there is an increase in the presence of macrophages in oral potentially malignant disorders, and these cells may be involved in the carcinogenesis process.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004059/pdfft?md5=49ffae0ce521e88d6d698e2aa19047e5&pid=1-s2.0-S2772906024004059-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141401968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative method of fabrication of complete denture for abused tissues in maxilla-A case report","authors":"","doi":"10.1016/j.oor.2024.100550","DOIUrl":"10.1016/j.oor.2024.100550","url":null,"abstract":"<div><h3>Background</h3><p>A fibrous or flabby ridge is a superficial area of soft, fleshy, mobile soft tissue which affects the alveolar ridge of maxilla or mandible. Conventional impression technique cannot be followed while making impression of flabby ridge area. Conventional acrylic denture cannot be given to individuals having flabby ridge area because hard surface of denture makes uncomfortable to the patients.</p></div><div><h3>Case report</h3><p>A 55 year old male patient had a history of wearing a maxillary complete denture for 5 years. Denture was ill fitting and no retention were present. On intraoral examination, a completely edentulous maxillary arch with inflamed movable flabby tissue was existing in the anterior region. The management started with making diagnostic impression with alginate material and a window has been created in special tray while making a secondary impression. Then border moulding has been done followed by secondary impression. In flabby ridge area it is recorded with the help of light body addition silicone. Then jaw relation and wax try in was done. While processing the denture soft liner was used to cover flabby area which provides the cushioning effect.</p></div><div><h3>Conclusion</h3><p>Implementation of some modifications in current impression techniques and newly introduced materials with improved physical and handling properties, flabby ridges can be treated effectively without any additional visits of patients in clinical practice.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024003960/pdfft?md5=14c09044e8e2d68d4de83a0aa19f6802&pid=1-s2.0-S2772906024003960-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141398321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring efferocytosis in oral cancer: Implications for treatment strategies and prognostic insights","authors":"Ramadurai Murugan,&nbsp;Monisha Prasad","doi":"10.1016/j.oor.2024.100565","DOIUrl":"10.1016/j.oor.2024.100565","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004114/pdfft?md5=cd895eab5fc83eea872a5875df910e1b&pid=1-s2.0-S2772906024004114-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141409070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}