Rizaldy Taslim Pinzon, Marlyna Afifudin, Ananda Digdoyo, Fx Kevin Christiansen Naibaho, Petra Gusti Parikesit, Yoel Sasamu Allendio
{"title":"Foster Kennedy Syndrome from Frontal Lobe Meningioma: A Rare Case Report.","authors":"Rizaldy Taslim Pinzon, Marlyna Afifudin, Ananda Digdoyo, Fx Kevin Christiansen Naibaho, Petra Gusti Parikesit, Yoel Sasamu Allendio","doi":"10.22336/rjo.2025.43","DOIUrl":"10.22336/rjo.2025.43","url":null,"abstract":"<p><strong>Background: </strong>Foster Kennedy syndrome is a neuro-ophthalmological disorder characterized by ipsilateral vision loss in one eye, followed by clinically significant papilledema in the opposite eye. The presence of mass lesions in the frontal lobe is primarily responsible for this syndrome. This case report further discusses symblepharon as an ocular manifestation of SJS.</p><p><strong>Method: </strong>A case report.</p><p><strong>Case report: </strong>We present a case of a 59-year-old female with a history of progressive headache, anosmia, mental status changes, and progressive poor vision. Ocular examination revealed disc pallor in her left eye with disc oedema in the contralateral eye. The patient was sent for computerized tomography (CT) and MRI, and the diagnosis of frontal lobe meningioma was confirmed. The surgical removal was performed, and the condition improved gradually.</p><p><strong>Discussion: </strong>We present a case of Foster Kennedy Syndrome, a rare neurological sign characterized by optic atrophy (vision loss) in one eye and papilledema (swelling of the optic nerve) in the other eye, often associated with an intracranial mass (meningioma).</p><p><strong>Conclusion: </strong>Presence of cranial fossa meningioma related to direct compression of a unilateral optic nerve, resulting in optic atrophy and might induce a rise in intracranial pressure, resulting in contralateral papilledema. This case presentation demonstrated that prompt and appropriate treatment was effective in gradually reducing the deterioration of symptoms associated with Foster Kennedy syndrome.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 2","pages":"271-274"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ganglion Cell Layer Thickness as a Biomarker for Amyotrophic Lateral Sclerosis Functional Outcome: An OCT study.","authors":"Divya Singh, Somya Singhal, Vikas Kanaujiya, Ankita Ranjan, Vinita Elizabeth Mani, Vimal Kumar Paliwal, Vaibhav Jain, Ankita Aishwarya, Rachna Agarwal","doi":"10.22336/rjo.2025.32","DOIUrl":"10.22336/rjo.2025.32","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to evaluate various optical coherence tomography (OCT) parameters in patients diagnosed with amyotrophic lateral sclerosis (ALS).</p><p><strong>Methods: </strong>Assessment of BCVA was done using Snellen charts, and subjective refraction was done to achieve a BCVA for distance and near. Measurement of intraocular pressure (IOP) was done with Goldman applanation tonometry. Stereoscopic fundus examination was performed using a 90D lens to assess the status of the optic nerve and retina, ruling out any ocular pathology. The patients were then subjected to OCT scanning to measure optic nerve head and macular parameters. Optical coherence tomography was performed using CIRRUS™ HD OCT (500-21822) (version 8.0.0.518) (Carl Zeiss Meditec, Dublin, CA, USA). The analyzed area was centered manually, and the absence of segmentation errors was confirmed for each scan.</p><p><strong>Results: </strong>RE Avg RNFL and LE Avg RNFL showed weak correlations with ALSFRS, indicated by Pearson Correlation coefficients of 0.073 and -0.026, respectively. The p-values (0.637 and 0.86) suggested that these correlations were not statistically significant. RE Avg GCL and LE Avg GCL, on the other hand, exhibited moderate positive correlations with ALSFRS scores, with correlation coefficients of 0.337 (RE) and 0.389 (LE). These correlations were statistically significant, as indicated by p-values of 0.021 and 0.006, respectively, suggesting a substantial association between GCL thickness and ALS functional outcomes.</p><p><strong>Discussion: </strong>All patients in our study were clinically diagnosed cases of ALS, as per the El Escorial criteria. Age group-wise analysis showed statistically significant thinning overall as well as quadrant-wise RNFL parameters in patients less than 50 years compared to age-matched controls, indicating that the pathological process occurring in larger motor neurons in ALS might also be happening in smaller sensory neurons of the retina, causing thinning, which was not due to age-related process. Although GCIPL thinning was occurring in our cases, though statistically not significant compared to control, the significant positive correlation observed between GCIPL and ALS functional outcome and between RNFL and GCIPL measurements highlighted the fact that though the axonal degeneration in retinal neurons might not be translating to the same extent in ganglion cells in ALS, the subtle thinning of GCIPL correlated strongly with functional disability in patients with ALS, implying better functional scores with higher values of GCIPL parameters.</p><p><strong>Conclusion: </strong>In summary, GCL measurements in both eyes showed a notable relationship with ALSFRS, whereas RNFL did not appear to correlate significantly.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 2","pages":"200-207"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrada-Elena Mirescu, Dan George Deleanu, George Baltă, Ioana Teodora Tofolean, Florian Baltă, Irina-Elena Cristescu, Sanda Jurja
{"title":"Retinal Vascular Diseases Highlighted by Adaptive Optics Ophthalmoscopy.","authors":"Andrada-Elena Mirescu, Dan George Deleanu, George Baltă, Ioana Teodora Tofolean, Florian Baltă, Irina-Elena Cristescu, Sanda Jurja","doi":"10.22336/rjo.2025.37","DOIUrl":"10.22336/rjo.2025.37","url":null,"abstract":"<p><strong>Objective: </strong>Our objective was to assess retinal microcirculation and photoreceptor parameters in both healthy individuals and patients with vascular retinal diseases using adaptive optics ophthalmoscopy. This technology enhances optical system resolution to 2 µm by correcting wavefront aberrations, revolutionizing in vivo studies of ocular structures.</p><p><strong>Materials and methods: </strong>Our study examined the clinical applications of adaptive optics in both healthy individuals and patients with vascular retinal diseases, including nonproliferative diabetic retinopathy, proliferative diabetic retinopathy, and macular telangiectasia (MacTel) type 2.</p><p><strong>Results: </strong>In our study, we observed a higher wall-to-lumen ratio (WLR) value in our patient with proliferative diabetic retinopathy compared to our healthy volunteer. Additionally, we found a positive correlation between WLR and the severity of diabetic retinopathy. Furthermore, cone density was lower in all quadrants of our patient with proliferative diabetic retinopathy. For our patient diagnosed with MacTel type 2, the cone mosaic appeared irregular and blurred, with notable cone loss, especially on the temporal side of the macula, consistent with the typical location of MacTel type 2 lesions.</p><p><strong>Discussion: </strong>Adaptive optics imaging assesses retinal changes in vascular diseases despite acquisition challenges. The obtained images aid in tracking the progression of diabetic retinopathy and detecting early changes of MacTel Type 2. Our study highlights both vascular and photoreceptor changes, quantifying these parameters to enhance the understanding of these vascular diseases.</p><p><strong>Conclusions: </strong>Adaptive optics imaging is an advanced technique that provides high-resolution visualization of the microstructure of retinal vasculature and photoreceptors. This technology enhances our understanding of both healthy and vascular retinal conditions, aiding in diagnosis, monitoring, and prognosis.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 2","pages":"235-242"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hidden peril: Large ciliary body melanoma imitating cataract in a cardiac patient.","authors":"Sonali Vinay Kumar, Manoj Gopal Madakshira, Vinay Kumar, Natasha Vinay Kumar, Sourabh Kumar","doi":"10.22336/rjo.2025.18","DOIUrl":"https://doi.org/10.22336/rjo.2025.18","url":null,"abstract":"<p><p>Ciliary body melanoma is a rare and aggressive ocular tumor that often presents with nonspecific symptoms, leading to delayed diagnosis. This report presents the case of a 43-year-old male with a history of ischemic heart disease who presented with diminished vision in the left eye, initially attributed to a cataract. Despite prior evaluation, no sign of malignancy was detected, and the patient was advised to proceed with cataract surgery. The patient visited our center for a second opinion, where a comprehensive evaluation identified a large ciliary body melanoma extending into the anterior chamber. Management was challenging due to the patient's cardiac condition, as anticoagulant therapy could not be discontinued. Enucleation was performed to mitigate the high risk of hematogenous metastasis associated with the tumor's rich vasculature, ciliary body contraction, and potential extension through emissary canals. Histopathology confirmed the diagnosis of spindle cell melanoma. This case highlights the diagnostic complexities of ciliary body melanoma, which can masquerade as a common condition like cataract, emphasizing the need for vigilance in atypical presentations and the importance of thorough evaluation to avoid misdiagnosis. It also underscores the challenges in managing such tumors in patients with significant systemic comorbidities, requiring a multidisciplinary approach for optimal outcomes.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 1","pages":"115-120"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uncommon Therapeutic Approaches for Patients with Recurrent Central Serous Chorioretinopathy: case report and literature review.","authors":"Raluca Neacșa, Daniela Manasia, Mădălina-Elena Tobă","doi":"10.22336/rjo.2025.04","DOIUrl":"10.22336/rjo.2025.04","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of anti-VEGF (Vascular Endothelial Growth Factor) injections in the treatment of central serous chorioretinopathy (CSCR) is to help reduce fluid accumulation beneath the retina, promote resolution of retinal edema, and potentially prevent complications like permanent vision loss.The goal is to stabilize or improve vision by improving visual outcomes by reducing fluid and promoting retina reattachment.</p><p><strong>Case presentation: </strong>A 43-year-old Caucasian male presented with painless, decreased vision in the left eye. The diagnosis of central serous chorioretinopathy was made. After the anti-VEGF injections, the results were good, beyond expectations, and the OCT aspect was maintained at 6 months within normal limits of the foveal affected area without recording extra vision loss.</p><p><strong>Discussions: </strong>In CSCR, the retinal pigment epithelium (RPE) becomes compromised, causing fluid from the choroid to leak under the retina, leading to retinal or serous detachment of the macula. While the exact cause of CSCR is not fully understood, it is believed that the increased permeability of the choroidal vessels, often due to elevated VEGF levels, contributes to fluid leakage. The specific goals of using anti-VEGF injections in CSCR include reducing choroidal vascular leakage, promoting fluid reabsorption, and preventing recurrence or progression.</p><p><strong>Conclusion: </strong>Anti-VEGF agents like aflibercept and ranibizumab are commonly used in treating CSCR, though their effectiveness can vary, and treatment regimens depend on individual patient response. Typically, anti-VEGF injections are administered via intravitreal injection into the eye, with repeat injections, if necessary, based on monitoring the patient's condition.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 1","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nirupama Kasturi, Mary Stephen, Pacha Pavani, Priyanka Mohan
{"title":"Blue dot cataract with Sutural cataract: A rare association and its management.","authors":"Nirupama Kasturi, Mary Stephen, Pacha Pavani, Priyanka Mohan","doi":"10.22336/rjo.2025.19","DOIUrl":"https://doi.org/10.22336/rjo.2025.19","url":null,"abstract":"<p><p>Cataracts are one of the leading causes of reversible blindness worldwide in the paediatric population. In general, paediatric cataracts significantly impact the child's visual development and their family, both emotionally and financially. However, certain developmental cataracts, like blue dot cataracts, are innocuous and will not cause visual morbidity. A sutural cataract involves the opacification of the anterior and posterior Y sutures, which can rarely affect vision. This is a case report of a 20-year-old male with vision loss, a rare association of blue dot cataract, sutural cataract, and significant astigmatism managed with uncomplicated phacoemulsification and Toric intra-ocular lens. Coexistence of blue dot cataracts with sutural cataracts is often rare, as is the presentation in the third decade of life with vision loss.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 1","pages":"121-123"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inclusive Marketing in Ophthalmology: building the consumers' experiences.","authors":"Consuela-Mădălina Gheorghe","doi":"10.22336/rjo.2025.01","DOIUrl":"https://doi.org/10.22336/rjo.2025.01","url":null,"abstract":"","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Radomir Babovic, Ben Burton, Nimesha Alex, Lakshmi Harihar, Tihomir Dugandzija
{"title":"Unraveling the Mystery of Taxol-Induced Cystoid Macular Oedema: Case Report and Literature Review.","authors":"Radomir Babovic, Ben Burton, Nimesha Alex, Lakshmi Harihar, Tihomir Dugandzija","doi":"10.22336/rjo.2025.02","DOIUrl":"https://doi.org/10.22336/rjo.2025.02","url":null,"abstract":"<p><strong>Objectives: </strong>The primary aim of this article is to present cystoid macular oedema as one of the side effects of Paclitaxel (Taxol) chemotherapy. Paclitaxel is used as a treatment option in patients with different types of solid carcinomas. The potential loss of vision, already altered by the disease, further compromises their quality of life, a contributing factor to overall psychological and mental decline.</p><p><strong>Case presentation: </strong>A 69-year-old woman developed a drop in visual acuity that was painless, bilateral, and accompanied by wavy lines. This occurred six months after starting Paclitaxel chemotherapy for metastatic breast cancer. The diagnosis of cystoid macular oedema caused by Paclitaxel was made. The visual acuity significantly improved after Paclitaxel was discontinued, and the symptoms subsided.</p><p><strong>Discussion: </strong>Paclitaxel is a chemotherapy drug used to treat various types of cancers and has been associated with cystoid macular oedema (CMO) in rare cases. CMO is thought to result from the disruption of the normal blood-retinal barrier. The specific mechanism remains incompletely understood, and multiple mechanisms have been postulated. In typical CMO, leakage from parafoveal capillaries is demonstrated on fluorescein angiograms in a classic petaloid pattern. However, in Taxane-Drug Induced CMO (TDICMO), there is no evidence of fluorescein leakage on angiography. TDICMO is a rare drug side effect of breast cancer treatment, described just 14 times in the English literature.</p><p><strong>Conclusion: </strong>It is crucial to reiterate that if a patient undergoing Paclitaxel treatment experiences any vision changes, it is imperative to consult an ophthalmologist for a thorough evaluation and appropriate management. This step is essential for the patient's well-being and to ensure the best possible outcome.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 1","pages":"3-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Disguised Threat: Rhino-Orbital Mucormycosis Masquerading as Acute Dacryocystitis.","authors":"Sonali Vinay Kumar, Vikas Sharma, Manoj Gopal Madakshira, Vinay Kumar, Natasha Vinay Kumar, Alok Sati","doi":"10.22336/rjo.2025.23","DOIUrl":"10.22336/rjo.2025.23","url":null,"abstract":"<p><p>Mucormycosis is an aggressive, life-threatening fungal infection predominantly affecting immunocompromised individuals. It typically manifests as rhino-orbital or rhino-cerebral disease. However, rarely, its initial presentation may closely resemble an innocuous condition like acute dacryocystitis, which is prone to result in higher morbidity rates. Herein, we report a case of a 52-year-old diabetic patient who presented with symptoms suggestive of acute dacryocystitis. Broad-spectrum antibiotics were started, but the patient did not improve with therapy. Further investigations, including imaging and biopsy, unraveled invasive mucormycosis. Prompt surgical debridement and antifungal therapy were initiated, but the delayed diagnosis culminated in significant orbital involvement. A high index of clinical suspicion is warranted for mucormycosis in patients with risk factors such as diabetes or immunosuppression who present with dacryocystitis and are unresponsive to standard treatment. Early diagnosis and aggressive intervention play a pivotal role in improving patient outcomes in this condition.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 1","pages":"138-143"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute anterior uveitis after photorefractive keratectomy: Demographic profile and clinical characteristics.","authors":"Ashish Markan, Shivani Chabbra, Mohammed Ibrahime Asif, Rahil Chaudhary, Manasi Tripathi","doi":"10.22336/rjo.2025.09","DOIUrl":"https://doi.org/10.22336/rjo.2025.09","url":null,"abstract":"<p><strong>Objective: </strong>To report demographic profile and clinical characteristics of acute anterior uveitis (AAU) after Photorefractive Keratectomy (PRK).</p><p><strong>Materials and methods: </strong>This retrospective study reviewed records of all patients who underwent PRK to correct ametropia between July 2021 and June 2023. Patients who developed postoperative AAU were included for evaluation. Demographic details, preoperative ocular examination, intraoperative details, postoperative examination, time to onset of AAU, grading of cells, flare and pigments, time to heal, and final visual outcome were analyzed.</p><p><strong>Results: </strong>Records of 390 patients who underwent PRK during the study period were reviewed. Of these, 16 (29 eyes, b/l:13 patients, u/l: 3 patients) presented with AAU following PRK. The mean age of patients was 27.43 + 4.53 years (range 22-32 years), with a mean spherical equivalent of -3.18 + 2.16 (range -2 to -7 D). Mean ablation depth was 55.13 + 28.10 mm (range 27-105 mm), and mean duration of excimer laser ablation was 11.27 + 8.31 seconds (range 3-36 seconds). The mean onset time of AAU post-surgery was 27.8 + 10.9 days (range 7-47 days). Most eyes (75.86%, n=22) had a moderate-intense grade of inflammation, while 82.75% (n=24) of the eyes had significant pigment dispersion. The mean healing time was 57.43 + 27.87 days (33-106 days). The median follow-up duration was 12 months (range 6-18 months). The incidence of AAU post-PRK in our study was 4.1%.</p><p><strong>Discussion: </strong>This study's incidence of post-PRK acute anterior uveitis (AAU) was 4.1%, aligning with previous reports of rare but significant inflammatory responses following PRK. The mean onset at 27.8 days suggested a delayed immune-mediated reaction rather than an immediate post-surgical response. While most cases had mild-to-moderate inflammation, a subset experienced severe reactions and ocular hypertension, reinforcing the need for close monitoring. The absence of systemic associations and posterior segment involvement suggested the role of a localized immune response. Despite the prolonged resolution time, all eyes achieved a final CDVA of 0 LogMAR, indicating favorable long-term outcomes with timely intervention and management.</p><p><strong>Conclusion: </strong>Anterior uveitis following PRK is infrequent. While it presents with marked anterior chamber reaction and pigment dispersion, the inflammation is often well-controlled with topical steroids. It does not affect the final visual outcome.</p>","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 1","pages":"48-52"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}