{"title":"A Comparative Evaluation of Change in Surface Roughness of Aesthetic Resin Composite Restorative Material on Exposure to Different Commonly Consumed Beverages: An <i>In vitro</i> Study.","authors":"Prabhu Varsha, Raju Chauhan","doi":"10.4103/jpbs.jpbs_1956_24","DOIUrl":"10.4103/jpbs.jpbs_1956_24","url":null,"abstract":"<p><strong>Background: </strong>Beverage consumption is commonly practiced by individuals of all age groups and is likewise known to cause pH alteration of the oral cavity, thereby, affecting the physical property of the restorative material like surface roughness.</p><p><strong>Aim: </strong>To assess surface roughness changes in four resin-based restorative materials (Ormocer, Giomer, Nanoceramic, and Nanohybrid composite) after exposure to commonly consumed beverages.</p><p><strong>Materials and methods: </strong>Two hundred composite discs were divided into four groups (Giomer, Ormocer, Nanoceramic, and Nanohybrid) and immersed in five subgroups (artificial saliva, carbonated beverage, carbonated fruit-based beverage, non-carbonated fruit-based beverage, and black coffee) for 21 days. Surface roughness was measured using a surface profilometer, and statistical analysis was performed using ANOVA and Tukey's test.</p><p><strong>Results: </strong>Nanohybrid (Group 4) exposed to carbonated beverages showed the highest roughness (Ra = 2.439 ± 0.797 μm). Nanoceramic (Group 3) exhibited the lowest roughness (Ra = 1.537 ± 0.305 mm), demonstrating superior resistance to surface degradation.</p><p><strong>Conclusion: </strong>Nanoceramic composite resin showed the least surface roughness changes and was highly resistant against all erosive beverages.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S535-S537"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Cross-Sectional Study of Depression in Rheumatoid Arthritis Patients at a Tertiary Care Center.","authors":"Hansraj Parmar, Prakash Joshi, Reena Singh, Sachin Parmar, Ranjana Sharma","doi":"10.4103/jpbs.jpbs_1478_24","DOIUrl":"10.4103/jpbs.jpbs_1478_24","url":null,"abstract":"<p><strong>Background: </strong>Rheumatoid arthritis (RA) is a chronic autoimmune condition often linked with depression, worsening symptoms, and lowering the quality of life. This study evaluated the prevalence of depression in female RA patients and its relationship with RA activity and inflammatory markers.</p><p><strong>Material and methods: </strong>A cross-sectional study was conducted over 18 months, involving 185 female RA patients with depression, diagnosed using DSM-5 criteria. RA disease activity was assessed using the Disease Activity Score 28 (DAS 28), and inflammatory markers, including CRP, ESR, RF, and anti-CCP, were evaluated. Data analysis was performed using SPSS version 20.0.</p><p><strong>Results: </strong>Depression was present in 72.4% of patients, with mild, moderate, and severe depression observed in 31.4%, 26.5%, and 14.6%, respectively. Significant associations were found between depression severity and RA activity (<i>P</i> = 0.000). Elevated CRP and ESR levels were seen in 81.6% and 89.7% of patients, correlating with depression severity. Rheumatoid markers (RF and Anti-CCP) were also significantly linked to both RA activity and depression.</p><p><strong>Conclusion: </strong>High depression prevalence in RA patients, especially those with severe disease activity, highlights the need for integrated mental health and RA care to enhance patient outcomes.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S634-S637"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Morphometric Examination of Tibial Tuberosity in North Indian Population.","authors":"Mohammad Rehan Asad","doi":"10.4103/jpbs.jpbs_1798_24","DOIUrl":"10.4103/jpbs.jpbs_1798_24","url":null,"abstract":"<p><strong>Background: </strong>Determining the morphometry and prominence of the tibial tuberosity was the primary goal of the current investigation. Tibial tuberosity morphometric data may be utilized to direct therapy and track the results of total knee replacement surgery. As a tractional apophysis, the tibial tuberosity may be the location of repeated avulsion fractures.</p><p><strong>Material and methods: </strong>Fifty (35 right and 35 left) completely ossified dry tibiae of unknown sex were obtained from the Department of Anatomy for the current investigation. A Vernier caliper was used to collect morphometric measurements of the tibial tuberosity. A statistical study was conducted on the parameters.</p><p><strong>Result: </strong>It was determined that the right side's lower rough section of the tibial tuberosity measured 47.77 ± 6.08 mm (range = 35.6-52.8 mm) and 46.84 ± 6.12 mm (range = 37.3-56.3 mm). The bottom rough portion of the tibial tuberosity measured 47.30 ± 5.97 mm in total. Although the difference between the two sides was statistically insignificant (<i>P</i> = .729), it was found to be greater on the left. The length of the lower rough portion of the tibial tuberosity on both sides was greater in the North Indian population when comparing the lengths of the top smooth and lower rough parts.</p><p><strong>Conclusion: </strong>Anatomists, orthopedicians, radiologists, rehabilitation experts, and sports medicine professionals will find the study's findings useful in assessing anterior knee pain syndrome.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S869-S872"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Karthik Prasad, Sheenam Markan, Mahishi G Suthar, Sweta Samal, Almazyad Yaser, Elaprolu Mallikarjun, Panthi Patel
{"title":"Comparative Analysis of Antimicrobial Efficacy of Sodium Hypochlorite and Chlorhexidine as Irrigants in Root Canal Therapy.","authors":"L Karthik Prasad, Sheenam Markan, Mahishi G Suthar, Sweta Samal, Almazyad Yaser, Elaprolu Mallikarjun, Panthi Patel","doi":"10.4103/jpbs.jpbs_1422_24","DOIUrl":"10.4103/jpbs.jpbs_1422_24","url":null,"abstract":"<p><strong>Objective: </strong>This research aims to analyze the antimicrobial efficacy of \"sodium hypochlorite (NaOCl)\" and \"chlorhexidine (CHX)\" as canal irrigants, evaluating their effects on bacterial load during \"Root canal treatment (RCT)\".</p><p><strong>Materials and methods: </strong>In this randomized controlled trial, 80 subjects requiring RCT were included. The participants were randomly allocated into two groups: Group A received 2.5% NaOCl as the irrigant, while Group B received 2% CHX. Microbial samples were gathered from the root canals using sterile paper points both before and after irrigation. The bacterial load was evaluated by counting \"colony-forming units (CFUs)\" following bacterial culture. Statistical analyzes were conducted using paired <i>t</i>-tests and ANOVA, with a significance level of <i>P</i> < 0.05.</p><p><strong>Results: </strong>Both NaOCl and CHX demonstrated substantial reductions in the bacterial load within the canal system. Group A (NaOCl) achieved a post-irrigation mean CFU count of 1.9 million, reflecting a 96% reduction in bacterial load. Group B (CHX) recorded a mean CFU count of 6.7 million, corresponding to an 86% reduction. The difference in bacterial reduction between the two groups was statistically significant (<i>P</i> < 0.01), indicating that NaOCl was more effective than CHX as an irrigant.</p><p><strong>Conclusion: </strong>Sodium hypochlorite proved to be more efficient than chlorhexidine in reducing microbial counts in root canals. While NaOCl appears to offer superior bacterial reduction, CHX, due to its substantivity and lower cytotoxicity, may still have valuable roles in particular clinical contexts.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S454-S456"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonu Kumar Singh, Roshan Kumar Jha, Ranjit S Ambad, Rakesh Kumar Jha
{"title":"Comparative Analysis of Biomarkers in CAD: Evaluating Homocysteine, Lipid HS-CRP, Apo A, and ADMA.","authors":"Sonu Kumar Singh, Roshan Kumar Jha, Ranjit S Ambad, Rakesh Kumar Jha","doi":"10.4103/jpbs.jpbs_1962_24","DOIUrl":"10.4103/jpbs.jpbs_1962_24","url":null,"abstract":"<p><strong>Introduction: </strong>Coronary artery disease (CAD), resulting from the narrowing of coronary arteries that supply oxygen to the heart, poses a significant global health challenge.</p><p><strong>Materials and methods: </strong>To compare the levels of homocysteine, lipid profile, lipid ratios, HS-CRP, ADMA, and apolipoproteins in CAD patients with controls, this chapter analyzes risk factors, biomarkers, and clinical traits linked to coronary artery disease (CAD) through a case-control study involving 200 participants (100 CAD cases and 100 controls). The investigation focuses on demographic variables, traditional risk factors (e.g., hypertension, smoking, alcohol intake), and essential biochemical markers such as lipid profiles, homocysteine, and emerging biomarkers like HS-CRP, ADMA, and apolipoproteins (Apo A1 and Apo B).</p><p><strong>Results and conclusion: </strong>The findings underscore the interplay between traditional and emerging risk factors in CAD progression. LDL, homocysteine, and TC/HDL ratio emerge as robust predictors of CAD risk. The regression model's high explanatory power (R<sup>²</sup> =97.2%) validates these indicators for effective risk assessment.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S366-S368"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Evaluation of Antifungal Effect on Maxillofacial Silicone Material With and Without Inclusion of Pomegranate Peel Powder: An <i>In Vitro</i> Study.","authors":"Shweta Pandey, Alka Gupta, Harsh Chansoria, Mukesh Soni, Anju Mahor, Varsha Mangtani, P Suthakr, Ranjana Sharma","doi":"10.4103/jpbs.jpbs_1634_24","DOIUrl":"10.4103/jpbs.jpbs_1634_24","url":null,"abstract":"<p><strong>Background: </strong>Maxillofacial silicone prostheses are widely used for the restoration of facial defects resulting from trauma, congenital abnormalities, or surgeries. However, these prostheses are highly susceptible to fungal infections, particularly by <i>Candida albicans</i>, which can lead to material degradation, infections, and decreased longevity. Traditional disinfectants often cause color changes and material deterioration. Natural antifungal agents, such as pomegranate peel powder (PPP), offer a promising alternative due to their antimicrobial properties and biocompatibility.</p><p><strong>Materials and methods: </strong>This <i>in vitro</i> study evaluates the antifungal efficacy of maxillofacial silicone with and without the inclusion of pomegranate peel powder. Silicone samples were prepared in three groups: without PPP, with 0.2% PPP, and with 0.4% PPP. The antifungal effect against <i>Candida albicans</i> was tested using the disk diffusion method. Each sample was inoculated with fungal cultures, and the zones of inhibition were measured to assess antifungal activity. Statistical analysis was conducted to compare the differences in antifungal efficacy among the groups.</p><p><strong>Results: </strong>The results indicated that silicone samples with pomegranate peel powder showed significantly larger zones of inhibition compared to those without PPP. Silicone with 0.4% PPP exhibited the highest antifungal activity, followed by 0.2% PPP. The control group without PPP demonstrated minimal antifungal efficacy. This suggests a dose-dependent relationship between the concentration of PPP and the inhibition of fungal growth.</p><p><strong>Conclusion: </strong>The inclusion of pomegranate peel powder in maxillofacial silicone significantly enhances its antifungal properties against <i>Candida albicans</i>. This study highlights the potential of natural compounds, like PPP, to improve the infection resistance and longevity of silicone prostheses. Further research is recommended to validate these findings in clinical settings and explore the long-term stability of such materials.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S342-S345"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Systemic Review of Pharmacological Management of Pediatric Obesity.","authors":"Surendra Gupta","doi":"10.4103/jpbs.jpbs_661_24","DOIUrl":"10.4103/jpbs.jpbs_661_24","url":null,"abstract":"<p><strong>Background: </strong>There is a growing need for safe and effective treatment due to the rise in child obesity rates worldwide. The effectiveness and safety of pediatric obesity drugs were reviewed in this systematic review based on international research.</p><p><strong>Techniques: </strong>PubMed, Cochrane Library, and Embase searches were performed to locate pediatric randomized controlled trials of antiobesity medications. Demographics, medication effectiveness, adverse events, and quality of life were all analyzed.</p><p><strong>Findings: </strong>There were 12 studies totaling 4,331 children in the review. The age range of the participants was 8.8 to 16.3 years, and their baseline BMI was between 26.2 and 41.7 kg/m<sup>2</sup>. Medication combinations such as phentermine/topiramate, metformin, extended-release metformin, topiramate, exenatide, and liraglutide were frequently studied. The amount that each medication decreased BMI varied somewhat, with liraglutide exhibiting the most decrease (-5.88 kg/m<sup>2</sup>). Comparator groups and pediatric antiobesity medication users experienced comparable adverse events and study discontinuation rates. Medication dose adjustments were more common in pediatric cases (10.6% vs. 1.7%; RR = 3.74 [95% CI: 1.51 to 9.26]). Quality of life increased in all trials, however, not specifically for pediatric cases.</p><p><strong>Conclusion: </strong>In conclusion, metformin, topiramate, exenatide, liraglutide, and the combination of topiramate and phentermine may lower BMI in children; however, more studies are required to ascertain their long-term safety and effectiveness. Children and adolescents with pediatric obesity may benefit from a tailored, multidisciplinary strategy that incorporates lifestyle modifications, pharmaceutical therapies, and psychological support to assist manage the condition and enhance the health and well-being of those affected.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S215-S221"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancements in Robotics and AI Transforming Surgery and Rehabilitation.","authors":"Zebanaz Jahangir Ansari, Ashwini Aher, Sunil Namdeo Thitame","doi":"10.4103/jpbs.jpbs_1937_24","DOIUrl":"10.4103/jpbs.jpbs_1937_24","url":null,"abstract":"<p><p>The use of AI and robotics in surgery and rehabilitation is transforming healthcare by improving accessibility, precision, and customization. Robotic devices provide for safer, more accurate, and shorter recovery periods during minimally invasive procedures. By offering real-time decision support and predictive analytics during procedures, AI enhances these developments. AI-powered solutions in rehabilitation use data from wearables and remote monitoring to generate customized treatment plans, increasing access to care, even in underprivileged areas. Through innovation, moral responsibility, and teamwork, robotics and AI are revolutionizing patient care and establishing new benchmarks for healthcare delivery. Robotic devices provide for safer, more accurate, and shorter recovery periods during minimally invasive procedures. By offering real-time decision support and predictive analytics during procedures, AI enhances these developments. AI-powered solutions in rehabilitation use data from wearables and remote monitoring to generate customized treatment plans, increasing access to care, even in underprivileged areas. Through innovation, moral responsibility, and teamwork, robotics, and AI are revolutionizing patient care and establishing new benchmarks for healthcare delivery.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S46-S48"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shraddha S Mane, Kanchan Sharma, Richa Pathak, Anisha Luthra, Ritika Gupta, Sameer Ahmed Khan, Subhangi Panda
{"title":"Assessment of Retention and Penetration Depth of Different Pit and Fissure Sealants: An <i>In-vitro</i> Study.","authors":"Shraddha S Mane, Kanchan Sharma, Richa Pathak, Anisha Luthra, Ritika Gupta, Sameer Ahmed Khan, Subhangi Panda","doi":"10.4103/jpbs.jpbs_458_25","DOIUrl":"10.4103/jpbs.jpbs_458_25","url":null,"abstract":"<p><strong>Aim: </strong>This <i>in-vitro</i> study aims to access the extent of penetration and retention of different sealants in deciduous molars.</p><p><strong>Materials and methods: </strong>Thirty extracted deciduous molars were split into three groups according to the kind of sealants applied. The specimens were divided into the equal numbers after acid etching and sealant application in Group 1: Conventional sealant (Fuji VII GIC, GC Corporation, Tokyo, Japan), Group 2: Colored resin-based-fluoride fissure sealant (Delton FS+ Dentsply, Germany), and Group 3: Nano-silver-reinforced fissure sealant (Kids-e-dental LLP, India) was done. Prepared samples were thermocycle and examined for retention using Simonsen's criterion. Further these samples were coated with nail varnish and soaked in methylene blue solution (1%) for a day and cleaned with distilled water. Buccolingual sectioning of prepared samples was done to examined under a stereomicroscope (SEM) at a magnification of 10X and score by trained examiner based on the sealant penetration depth criteria MLC Fracasso in millimeters. The Non-Parametric Kruskal Wallis H test was used to analyses all the data. 100% retention was found in group 3 followed by group 2 then 1.</p><p><strong>Result and conclusion: </strong>Frequency sealant penetration depth comparison was found significant difference between the groups. Nano-silver-reinforced sealant represented improved retention and penetration as related to the resin-based-fluoride fissure sealant and conventional sealants.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S718-S720"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B V H Ravi Teja, Jayakrishna Babu, Lokesh Sunkala, V Bhanu Chander, K V Gurucharan Karthik, Jisa A Alex
{"title":"Comparative Evaluation of the Efficacy of Mouthwash and Denture Cleanser in the Removal of Candida Albicans from Two Flexible Denture Base Materials - An <i>In vitro</i> Study.","authors":"B V H Ravi Teja, Jayakrishna Babu, Lokesh Sunkala, V Bhanu Chander, K V Gurucharan Karthik, Jisa A Alex","doi":"10.4103/jpbs.jpbs_527_25","DOIUrl":"10.4103/jpbs.jpbs_527_25","url":null,"abstract":"<p><strong>Background: </strong>Poly-methyl methacrylate is the most common denture base material but has limitations. Flexible denture base materials, such as Lucitone FRS and Valplast, were introduced to address these issues. Denture success depends on preventing microbial attachment and easy cleaning. This study evaluates the efficacy of Clinsodent denture cleanser and 0.2% Chlorhexidine (Rexidine) mouthwash in removing Candida albicans from these materials.</p><p><strong>Methodology: </strong>Forty-eight specimens were subdivided into three groups, with eight in each. After inoculation with Candida albicans, samples were treated with distilled water (control), 0.2% Rexidine mouthwash, or Clinsodent cleanser. Colony counts were analyzed.</p><p><strong>Results: </strong>Rexidine mouthwash was more effective than Clinsodent. Valplast showed higher initial Candida growth, indicating Lucitone FRS is more resistant.</p><p><strong>Conclusion: </strong>0.2% Rexidine mouthwash was superior in Candida removal, and Lucitone FRS exhibited greater resistance than Valplast.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S786-S788"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}