{"title":"A New Approach to Haemodialysis: Nurse-Led Dual Intervention Eases AV-Fistula Puncture Pain and Discomfort.","authors":"Divya Bharathi Jayaraman, Theranirajan Ethiraj, Shankar Shanmugam Rajendran, Duraikannu Anandhi, Venba Elangovan, Deepika Ramalingam, Shabana Ahamed","doi":"10.4103/jpbs.jpbs_1619_24","DOIUrl":"10.4103/jpbs.jpbs_1619_24","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease (CKD) affects approximately 10% of the global population and often progresses to end-stage renal disease, necessitating hemodialysis. Arteriovenous (AV) fistula puncture is a routine yet painful procedure, highlighting the need for effective pain management strategies.</p><p><strong>Objective: </strong>This study aimed to evaluate the effectiveness of a Nurse-Led Dual Intervention, combining cryotherapy and virtual reality, in reducing pain and discomfort during AV fistula puncture among hemodialysis patients.</p><p><strong>Methods: </strong>A randomized controlled trial was conducted with 60 hemodialysis patients assigned to either an experimental or control group. Pain and discomfort were assessed using McGill's Pain Rating Scale and Borg's Perceived Discomfort Rating Scale. The intervention involved the simultaneous application of cryotherapy and virtual reality distraction during AV fistula puncture, while the control group received standard care.</p><p><strong>Results: </strong>Post-intervention analysis demonstrated a 43.62% reduction in symptom scores in the experimental group compared to a 2.80% reduction in the control group. Significant decreases in pain intensity and discomfort scores were observed in the experimental group. Additionally, statistical analysis revealed meaningful associations between socio-demographic variables and pain management outcomes.</p><p><strong>Conclusion: </strong>The findings suggest that integrating non-pharmacological interventions, such as cryotherapy and virtual reality, can significantly improve patient comfort and quality of life during hemodialysis. Future research should explore the broader clinical applications of this dual intervention for pain management in various healthcare settings.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S691-S693"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adjunctive Efficacy of Superior Hypogastric Plexus Block in Chronic Pelvic Pain: A Comprehensive Review.","authors":"Vivek Chakole, Shrilekh Mankhair, Priyanka Dev, Jeshnu Tople, Ranjit S Ambad","doi":"10.4103/jpbs.jpbs_1812_24","DOIUrl":"10.4103/jpbs.jpbs_1812_24","url":null,"abstract":"<p><p>Chronic pelvic pain (CPP) is a prevalent and complex condition that affects millions worldwide, predominantly women, and poses significant challenges in both diagnosis and management. Despite a wide array of pharmacological and nonpharmacological treatments, many patients experience persistent pain, reduced quality of life, and limited functional capacity. The superior hypogastric plexus block (SHPB) has emerged as a promising interventional technique for the management of CPP, particularly in cases with predominant visceral pain components. This comprehensive review aims to evaluate the adjunctive efficacy of SHPB in treating CPP, exploring its anatomical basis, mechanisms of action, and clinical outcomes. SHPB targets the superior hypogastric plexus, a crucial relay center for transmitting nociceptive signals from the pelvic organs. By interrupting these pathways, SHPB can relieve pain and improve associated symptoms such as dysmenorrhea, dyspareunia, and dysuria. This review systematically analyzes the existing literature on SHPB, comparing its effectiveness with other interventional techniques and its role as an adjunct to standard therapies. Evidence suggests that SHPB can significantly reduce pain scores and improve the quality of life in selected patients with a relatively low risk of complications.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S117-S120"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nirav Patel, Kunal Jha, Velusamy Pavethynath, Sindhura Ravi, Siva K Pendyala, Samidha M Shinde, Rahul Tiwari
{"title":"Anterior Rehabilitation with Basal Implants in Cleft Cases Systematic Review.","authors":"Nirav Patel, Kunal Jha, Velusamy Pavethynath, Sindhura Ravi, Siva K Pendyala, Samidha M Shinde, Rahul Tiwari","doi":"10.4103/jpbs.jpbs_373_24","DOIUrl":"10.4103/jpbs.jpbs_373_24","url":null,"abstract":"<p><strong>Objective: </strong>To carefully examine the literature on anterior rehabilitation with basal implants in cleft patients, including clinical outcomes, success rates, and complications.</p><p><strong>Methods: </strong>A PubMed search was extensive for published research. The inclusion criteria were original research studies on basal implants in anterior cleft rehabilitation, including clinical outcomes, success rates, and complications, with a minimum follow-up period of 6 months. The Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Analytical Cross-Sectional Studies assessed the quality of the included studies after data were retrieved and synthesized using a standard form.</p><p><strong>Results: </strong>The review identified four papers that matched the criteria. The trials examined clinical and surgical care, two-stage implant surgery results, and orthodontic treatment with bone grafting and implant implantation. Infection, complication, and success rates were examined across trials.</p><p><strong>Conclusion: </strong>The included trials found 100% success with anterior rehabilitation with basal implants for cleft lip and palate. This method is safe and feasible because no infections or problems have been documented. Basal implants in cleft instances should be tested for long-term efficacy, safety, and patient satisfaction in well-designed clinical trials.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S211-S214"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Sriteja, Vs Lakshmi Thorreti, S V Ravindra, M Rohit, Sriharsha Pudi, Abnuri Karan Kumar
{"title":"Comparison and Evaluation of Various Drying Methods on Surface Hardness of Type IV Dental Stones: An <i>In vitro</i> Study.","authors":"D Sriteja, Vs Lakshmi Thorreti, S V Ravindra, M Rohit, Sriharsha Pudi, Abnuri Karan Kumar","doi":"10.4103/jpbs.jpbs_572_25","DOIUrl":"10.4103/jpbs.jpbs_572_25","url":null,"abstract":"<p><p>Accurate dental restorations require die materials with optimal surface hardness. This study evaluated drying method effects on three Type IV dental stones: Elite Rock (ZERMACK), Fuji Rock (GC), and Kal Rock (KALROCK). One hundred twenty samples of ZERMACK, GC, and KALROCK were prepared using manufacturer-recommended water/powder ratios. Samples were divided into four subgroups based on drying method: 1-hour air drying, 24-hour air drying, 1-hour air drying followed by 10 min of microwave drying at low power, and 24-hour air drying followed by die hardener application. Knoop hardness testing was conducted according to ADA specification #25. One-way ANOVA and pairwise comparisons were used for statistical analysis. GC showed the highest mean hardness (84.58), followed by ZERMACK (74.82), and KALROCK (67.07). Significant differences existed (F [2, 27] =190.463, <i>P</i> < .001). GC had significantly higher hardness than KALROCK (17.52 difference) and ZERMACK (9.76 difference) after 24 hours. GC exhibited superior surface hardness. Material selection and drying methods significantly impact Type IV gypsum hardness for dental dies.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S777-S779"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Token Economy Therapy in Reducing Aggressive Behaviors Among Orphanage Children: A Pilot Study.","authors":"Jaya J Varghese, Shweta Joshi, S Prema, J Jasmine Jesy, Sadhana Adhyapak, Jamadar Khurshid","doi":"10.4103/jpbs.jpbs_1888_24","DOIUrl":"10.4103/jpbs.jpbs_1888_24","url":null,"abstract":"<p><strong>Background: </strong>Children in orphanages often display aggressive behaviours due to limited personalized care and emotional support. Token economy therapy, which uses positive reinforcement strategies, may offer a promising behavioural intervention in such settings. This pilot study evaluates the effectiveness of token economy therapy in reducing aggression among orphanage children.</p><p><strong>Methods: </strong>A quasi-experimental design was adopted involving 50 children aged 6-12 years from two orphanages in Pune, India. Stratified random sampling ensured balanced representation by age and gender. The intervention consisted of 20 biweekly token economy sessions over 10 weeks, wherein desirable behaviours were rewarded with tokens exchangeable for preferred items. Behavioural assessments were conducted pre- and post-intervention using the Strengths and Difficulties Questionnaire (SDQ). Wilcoxon signed-rank test was used for statistical analysis.</p><p><strong>Results: </strong>Pre-intervention, 76% of children had moderate behavioural difficulties and 24% had severe difficulties. Post-intervention, 36% exhibited normal behaviour and 64% showed only mild difficulties. Mean behavioural scores significantly decreased from 34.42 (±2.64) to 16.34 (±1.72) (Wilcoxon Z = 6.18, <i>P</i> < 0.0001). Improvements were consistent across all academic performance categories.</p><p><strong>Conclusion: </strong>Token economy therapy proved effective in significantly reducing aggressive behaviours among orphanage children. Its structured, reward-based approach may offer a scalable and cost-effective behavioural intervention in institutional care settings. Further studies are warranted to confirm long-term benefits across broader populations.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S323-S325"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Various Interventions on Menstrual Health and Hygiene Among Adolescent Girls: A Systematic Review of Observational and Interventional Studies.","authors":"Kalpana Joshi, Deeplata Mendhe","doi":"10.4103/jpbs.jpbs_1636_24","DOIUrl":"10.4103/jpbs.jpbs_1636_24","url":null,"abstract":"<p><p>Menstrual health and hygiene (MHH) is essential for adolescent girls, yet many face challenges in accessing education and resources. This systematic review assesses the impact of various MHH interventions on knowledge, attitudes, and practices. A search of studies from 2000 to 2022 identified 10 relevant studies evaluating structured teaching programs, peer education, and community-based interventions. Results showed significant improvements in MHH awareness and behavior, particularly with peer-led and school-based programs. However, gaps persist, especially in rural areas. Community and school engagement are key to effective interventions, with future efforts needed to address awareness gaps in underserved populations.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S84-S87"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Depression and Anxiety in Couples Undergoing Infertility Treatment with Assisted Reproductive Techniques in Indian Context.","authors":"Shalini Gupta, Gaurav Chittora, Riyanshi Jaiman, Muskan Sharma","doi":"10.4103/jpbs.jpbs_1596_24","DOIUrl":"10.4103/jpbs.jpbs_1596_24","url":null,"abstract":"<p><strong>Background: </strong>Psychological distress has been linked to infertility and its treatment. However, the existing literature data are scarce concerning this issue in Indian couples.</p><p><strong>Aim: </strong>To assess depression and anxiety in couples undergoing infertility treatment with assisted reproductive techniques (ARTs) in the Indian context.</p><p><strong>Methods: </strong>Hospital Anxiety and Depression Scale was used to assess depression and anxiety in 80 married couples who were undergoing treatment for infertility using assisted reproductive techniques at an Indian center.</p><p><strong>Results: </strong>The mean anxiety and depression scores were higher in females with 9.84 ± 2.04 and 10.74 ± 2.67, respectively (<i>P</i> = 0.02). High anxiety scores were seen in males aged 20-24 and 40-44 years with no prior treatment. With increasing age, mean depression scores decreased in both genders. Higher depression scores were seen in males during the first and 10 years of treatment, male infertility cause, and no prior treatment cases.</p><p><strong>Conclusions: </strong>Depression and anxiety prevalence in infertile couples undergoing treatment with ART is double compared to the general population. Mean depression scores had a significant association in both genders and with initial treatment, gender-based attribution, and duration of therapy in males.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S727-S729"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating the Effectiveness of Physiotherapy in the Management of Oral Submucous Fibrosis.","authors":"Nidhi Thakur, Rohit Sharma, Uday Narayan Sharma, Mysore K Sunil, Sunil Sharma, Niharika Sharma, Mrunal Meshram","doi":"10.4103/jpbs.jpbs_648_25","DOIUrl":"10.4103/jpbs.jpbs_648_25","url":null,"abstract":"<p><strong>Background: </strong>Oral Submucous Fibrosis (OSMF) is a chronic, progressive disorder leading to fibrosis, trismus, and burning sensation. Physiotherapy is a non-invasive approach aimed at improving oral mobility.</p><p><strong>Materials and methods: </strong>A total of 50 OSMF patients underwent daily physiotherapy exercises using ice cream sticks for six months. Mouth opening was measured at baseline, 1 month, 3 months, and 6 months. Pain levels were assessed using the Visual Analogue Scale (VAS).</p><p><strong>Results: </strong>Physiotherapy led to a moderate increase in mouth opening, but pain relief and symptom improvement were limited. Compliance was a challenge due to patient discomfort.</p><p><strong>Conclusion: </strong>Physiotherapy is a viable conservative treatment for OSMF but should be combined with adjunct therapies for better symptom management and long-term effectiveness.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S305-S307"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Nurse-Led Digital Education on Perimenopausal Women's Perception and Practices for Osteoporosis Prevention.","authors":"Umamaheswari Periyasamy, Theranirajan Ethiraj, Shankar Shanmugam Rajendran, Palani Tamilselvi, Ghercy Elumalai, Saranya Subbaiya, Sumathy Arumugam","doi":"10.4103/jpbs.jpbs_1622_24","DOIUrl":"10.4103/jpbs.jpbs_1622_24","url":null,"abstract":"<p><strong>Introduction: </strong>Osteoporosis represents a significant public health challenge for perimenopausal women, primarily due to hormonal changes, although awareness remains very low. This highlights the need for effective education interventions. Digital health education, especially those led by nurses, can enhance knowledge and practice through content that is specifically tailored and interactive.</p><p><strong>Objective: </strong>This study evaluates the effectiveness of a nurse-led digital education program in enhancing osteoporosis prevention knowledge and practices among perimenopausal women.</p><p><strong>Results: </strong>Using a quasi-experimental research design with a sample of 100 participants, the intervention led to significant improvements in the treatment group. Knowledge increased from 32.40% to 66.46%, and practices improved from 42.40% to 73.40%, compared to the control, which showed fewer changes.</p><p><strong>Conclusion: </strong>The results support the use of digital education in community healthcare to address knowledge gaps on osteoporosis prevention. Future interventions should consider demographic factors to improve effectiveness.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S682-S684"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P Narayana Prasad, Kanika Sharma, Hardeep Kaur, Mohd Amjad Tahseen, Somya Gupta, Shabina Shafi, Mrunal Meshram
{"title":"Evaluation of Periapical Radiolucency and Periodontal Bone Loss of Endodontically Treated Teeth Before and After Orthodontic Treatment Using Cone Beam Computed Tomography.","authors":"P Narayana Prasad, Kanika Sharma, Hardeep Kaur, Mohd Amjad Tahseen, Somya Gupta, Shabina Shafi, Mrunal Meshram","doi":"10.4103/jpbs.jpbs_546_25","DOIUrl":"10.4103/jpbs.jpbs_546_25","url":null,"abstract":"<p><strong>Background: </strong>The impact of using orthodontic therapy on the periapical radiolucency (PR) and alveolar bone loss in teeth that have received endodontic treatment has not been examined in any prior research.</p><p><strong>Aim: </strong>This study used cone-beam computed tomography (CBCT) to assess alveolar bone loss and PR surrounding endodontic treated teeth (ETT) both before and after orthodontic therapy.</p><p><strong>Methods and materials: </strong>This study was conducted involving 450 patients with ETT undergoing orthodontic treatment. The clinical and radiographic records of all patients included in this study were evaluated. Details regarding demographics, duration of orthodontic treatment, number of ETT, location of ETT, size of PR, alveolar bone dimension in ETT using CBCT.</p><p><strong>Results: </strong>It was observed that overall there was a decrease in the size of periapical lesion (PL) after orthodontic applaince (OA), however, the findings were not statistically significant. (<i>P</i> = 0.316). When there was the evaluation of alveolar bone loss, then it was observed that there was a decrease in the dimension of alveolar bone.</p><p><strong>Conclusion: </strong>There was a decrease in the size of the periapical lesion and dimensions of the alveolar bone around ETT after orthodontic treatment.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S822-S824"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}