Journal of pharmacy & bioallied sciences最新文献

{"title":"Accuracy and Stability of Clear Aligner Treatment: A Systematic Review.","authors":"V Vigneshkumar, E R Deepak, Vania Ferreira, Afshan S Waremani, N A K Nishaevitha, K Thankamani Ammal, Garima Singh","doi":"10.4103/jpbs.jpbs_1048_24","DOIUrl":"10.4103/jpbs.jpbs_1048_24","url":null,"abstract":"<p><p>This systematic review evaluates the long-term stability and retention of clear aligner treatment, focusing on factors like aligner compliance, attachment use, and treatment duration. Following PRISMA guidelines, we searched electronic databases and manual sources, identifying 112 records and narrowing down to six relevant studies. These studies compared clear aligners to traditional braces, highlighting their effectiveness, especially for mild crowding and anterior movements. Clear aligners, particularly Invisalign, showed benefits like shorter treatment times and higher patient satisfaction. However, variability in treatment accuracy and limited long-term follow-up indicate a need for further research. Overall, clear aligners offer a discreet, flexible, and effective orthodontic option.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3077-S3079"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing Predictive Indicators of Fever and Sepsis after Percutaneous Nephrolithotomy.","authors":"Gautam Zalavadiya, S Santhosh, Lata Ajay Tapnikar, Nikhil Ramesh Vaidya, Vivek Amritbhai Patel, Nilam V Patel","doi":"10.4103/jpbs.jpbs_1527_24","DOIUrl":"10.4103/jpbs.jpbs_1527_24","url":null,"abstract":"<p><strong>Aim: </strong>Our research aims to identify the factors that can help reduce the risk of complications and enhance patient safety.</p><p><strong>Material and methods: </strong>This was a single institutional, retrospective study over a period of 1 year. A total of 250 patients were included in the study, and the study variables recorded were analyzed statistically.</p><p><strong>Results: </strong>A total of 115 patients presented with stones larger than 25 millimeters, while 75 patients were diagnosed with staghorn stones. Our study revealed a statistical connection between severe sepsis following surgery and three key factors: stone size exceeding 25 millimeters, an operative duration longer than 120 minutes, and substantial bleeding that necessitated a transfusion.</p><p><strong>Conclusion: </strong>Experiencing a fever after PCNL is a common response; however, the likelihood of it developing into a serious condition, such as life-threatening severe sepsis and MODS, is quite low.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S4111-S4113"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Audio-Visual Modeling and its Effect on Behavior of Pediatric Patient: An Observational Study.","authors":"Sujata Kumari, Amreen Aijazuddin, Anand Nanasaheb Patil, Amish Diwanji, Ranadheer Eeraveni, Disha Makwani, Akshaya Ojha","doi":"10.4103/jpbs.jpbs_715_24","DOIUrl":"10.4103/jpbs.jpbs_715_24","url":null,"abstract":"<p><strong>Background: </strong>The prognosis and patients' cooperation are interdependent on each other. In case of children, this aspect becomes all the more highlighted because of heightened response to pain and anxiety.</p><p><strong>Material and methodology: </strong>Hundred (4-to-10 years old) children who were rated as negative on Frankl Behavior Rating Scale were taken for the study. The children were shown a video of a positive child model, and also various procedures of the dental treatment were shown.</p><p><strong>Results: </strong>Sixty-one children out of 100 demonstrated positive behavior and 3 showed definitely positive behavior during preventive treatment procedures. On the other hand, 73 children out of 100 demonstrated positive behavior and 3 showed definitely positive behavior during main treatment procedures. Significant change was observed in behavior of children in before and after the video was shown to them (<0.001).</p><p><strong>Conclusion: </strong>Audio-visual modeling has been proved to be a very efficient method in developing positive behavior of children toward dental treatment.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3197-S3199"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fracture Susceptibility in Non-Vital Apex Teeth Following Various Modified Apexification Procedure - An <i>In Vitro</i> Study.","authors":"N J Nagaraj, Peyush Pratap Singh Sikarwar, Debkant Jena, Rini Gangwal, Ipsita Mohanty, Adnan Haider Rizvi","doi":"10.4103/jpbs.jpbs_950_24","DOIUrl":"10.4103/jpbs.jpbs_950_24","url":null,"abstract":"<p><strong>Introduction and objective: </strong>The purpose of this research was to evaluate and compare the fracture resistance of juvenile teeth that were simulated and strengthened with two different root canal backfilling combinations (gutta-percha/AH26) and biodentine (BD) as apical barriers.</p><p><strong>Materials: </strong>Five groups (<i>n</i> = 10) of removed human maxillary incisors were randomly assigned. There was no instrumentation of the positive control group. To replicate juvenile teeth, coronal access was established for the other groups, and root canals were instrumented using the ProTaper up to F5. Six Peeso reamers were then permitted to pass 1 mm beyond the apex to size 6 (1.7 mm). Either mineral trioxide aggregate (MTA) or BD apical barrier was used to fill the top 4 mm of their root canals, and either gutta-percha or AH26 obturation combination was used as the backfill. Coronal access cavities were restored using composite resin. Universal testing equipment was used to record the maximum load required for each tooth to fracture. Analysis of variance was used to examine the data.</p><p><strong>Results: </strong>Compared to the negative control groups, the non-instrumented Group I had the greatest fracture resistance and varied considerably (<i>P</i> < 0.05). In contrast, regardless of the backfilling combination, there was no discernible difference between the BD and MTA groups (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>In terms of resistance to root fracture, there was no difference between the backfilling combination and the MTA and BD apical barriers.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3966-S3969"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probing the Clinical, Laboratory, and Sociodemographic Factors Associated with Malaria: A Case-Control Study.","authors":"Ritesh Upadhyay, Annasaheb J Dhumale, Chanchlesh Dehariya, Renu Waghmare, Amit Rangari","doi":"10.4103/jpbs.jpbs_1270_24","DOIUrl":"10.4103/jpbs.jpbs_1270_24","url":null,"abstract":"<p><strong>Background: </strong>The National Malaria Elimination Program (NMEP) has helped reduce the mortality from malaria in India, and there are alarmingly high mortality rates from anemia in certain geographical regions.</p><p><strong>Aim: </strong>To assess the clinical, laboratory, and sociodemographic factors associated with malaria from P. falciparum and P. vivax.</p><p><strong>Methods: </strong>This retrospective record-based clinical study subjects with malaria were further divided into P. vivax and P. falciparum cases. In all the cases, the clinical, laboratory, and sociodemographic factors were assessed. Data gathered were analyzed statistically.</p><p><strong>Results: </strong>During the study period, 222 cases of malaria were assessed where 22.52% (n = 50) and 74.48% (n = 172) cases were due to P. falciparum and P. vivax, respectively. Hepatomegaly was common in P. falciparum cases and splenomegaly in P. vivax cases. Thrombocytopenia was seen in 58.1% (n = 100) and 72% (n = 36) subjects with P. vivax and P. falciparum cases. No significant difference was seen in other laboratory parameters.</p><p><strong>Conclusions: </strong>Clinical, laboratory, and sociodemographic factors associated with malaria from P. falciparum and P. vivax have no statistically significant difference.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3793-S3795"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Evaluation of Surface Roughness of Different Composite Restorative Materials after Thermocycling and Prolonged Immersion in Common Beverages Using Atomic Force Microscopy-<i>In Vitro</i> Study.","authors":"Akanksha Malik, Anjali K Kothari, Riya Dave, Vinay V Rao, Kaushal Vyas, Deep P Agrawal, Kishan Patel","doi":"10.4103/jpbs.jpbs_731_24","DOIUrl":"10.4103/jpbs.jpbs_731_24","url":null,"abstract":"<p><strong>Background: </strong>Direct composite restorations face abrupt temperature changes, varying pH, and surface deterioration in the oral environment. Atomic force microscopy (AFM) provides visual and numerical data on surface roughness.</p><p><strong>Aim: </strong>This study evaluates and compares the surface roughness of composite restorative materials after simulating oral conditions.</p><p><strong>Materials and methods: </strong>Three composite groups (<i>n</i> = 16 each) were tested. Group A: Microhybrid, Group B: Nanofilled, and Group C: Nanohybrid. Each group was divided into four subgroups (<i>n</i> = 4 each): distilled water (control), black coffee, Coca-Cola, and Red Bull. After thermocycling and immersion, surface roughness was measured using AFM.</p><p><strong>Results: </strong>Nanocomposites with uniform monomodal fillers showed the least surface disintegration and superior properties.</p><p><strong>Conclusion: </strong>Resin chemistry, including filler size and matrix composition, is crucial for composite properties and performance under function.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3251-S3253"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11804997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probiotics in the Prevention and Treatment of Periodontal Diseases: A Systematic Review.","authors":"Nishath Sayed Abdul, Lara Ghassan Odeh, Asma Awadh Alenazi, Jumana Abdullah Alzahrani, Aldanah Tawfiq Almutib, Cristalle Soman","doi":"10.4103/jpbs.jpbs_681_24","DOIUrl":"10.4103/jpbs.jpbs_681_24","url":null,"abstract":"<p><strong>Introduction: </strong>Periodontal diseases (PDs) pose a significant challenge to dental health, leading to a growing interest in probiotics as potential therapeutic and prophylactic agents. Literature evidence has shown conflicting results on the use of probiotics in the management of PDs. Hence, this systematic review was performed to explore the effectiveness of probiotics in both the prevention and treatment of PDs by synthesizing data from relevant studies.</p><p><strong>Methodology: </strong>Various databases were searched using appropriate MeSH keywords as per the PRISMA protocol. Studies were included only if they met certain criteria. Two reviewers independently extracted data variables from the included literature. The risk of bias 2.0 tool was employed to assess the methodological quality of the included studies.</p><p><strong>Results: </strong>In total, 21 studies were considered eligible and included in the review. It was observed that 17 studies reported a statistically significant improvement in both periodontitis and gingivitis among the probiotic group compared to control cohorts. The synthesized evidence from the review suggests that probiotics play a favourable role in both the prevention and treatment of PDs.</p><p><strong>Conclusion: </strong>It also supports the incorporation of probiotics as a potential adjunctive therapy in PD management. However, further research is warranted to explore the specific probiotic strains, dosages, and treatment durations for optimized outcomes.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3302-S3307"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11804984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Dentinal Microcracks using Micro-CT after Root Canal Preparation with Different Rotary Endodontic File Systems.","authors":"Mohammed Mustafa, Kailash Attur, Sidharth S Menon, Shylaja Attur","doi":"10.4103/jpbs.jpbs_1274_24","DOIUrl":"10.4103/jpbs.jpbs_1274_24","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the propagation of dentinal microcracks in the mesiobuccal (MB) and mesiolingual (ML) canals following root canal preparation using two different rotary endodontic file systems, TruNatomy (continuous rotation) and MicroMega ONE RECI (reciprocating motion), using micro-computed tomography (micro-CT).</p><p><strong>Materials and methods: </strong>Fifty freshly extracted human mandibular first and second molars were selected based on specific inclusion criteria. Root canal preparation was confined to the MB and ML canals in mesial roots of mandibular molars (Vertucci Type IV canal configurations) using TruNatomy and MicroMega ONE RECI systems. Pre- and post- preparation scans were taken for all the specimens using micro-CT to identify and measure dentinal microcracks. Statistical analysis was performed using a t-test and Fisher's exact test, with significance set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>The results indicated no statistically significant differences between the two systems in terms of microcrack formation or propagation. In the ML canal, 8.0% of teeth prepared with TruNatomy and 12.0% with MicroMega ONE RECI exhibited microcracks (<i>P</i> = 0.643). In the MB canal, microcracks were found in 12.0% of the TruNatomy group and 8.0% of the MicroMega ONE RECI group (<i>P</i> = 0.643). Both systems showed a significant increase in canal volume, but no significant differences between the instruments (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Both TruNatomy and MicroMega ONE RECI demonstrated similar outcomes regarding dentinal microcrack formation and propagation in the MB and ML canals, with no significant differences. Both systems were effective in enlarging the canals while preserving the natural canal anatomy. These findings suggest that the choice of instrumentation system can be guided by clinical ease and efficiency as both systems offer comparable mechanical effects on dentin integrity during root canal preparation.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3796-S3802"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Patient Satisfaction and Acceptance of Acupuncture as an Alternative Therapy in Dental Practice.","authors":"Tapas K Sarkar, Divya Pandya, Mohit Sharma, Sandip Kulavi, Priyanka Dausage, Anwesha Banerjee","doi":"10.4103/jpbs.jpbs_1108_24","DOIUrl":"10.4103/jpbs.jpbs_1108_24","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate patient satisfaction and acceptance of acupuncture in dental practice.</p><p><strong>Methods: </strong>This randomized controlled study involved 30 participants (15 males, 15 females, mean age 38.2 years) requiring mandibular third molar extraction. Patients were randomly assigned to receive either real or placebo acupuncture. Pain intensity was assessed using a 4-point scale, and patients' acceptance of and satisfaction with acupuncture were measured. The study was conducted at an oral and maxillofacial surgery clinic.</p><p><strong>Results: </strong>Toothache was the most common dental issue (16.7%). Participants showed moderate to high levels of acceptance toward acupuncture (mean score of 3.37 on a 4-point scale) and satisfaction with the treatment (mean score of 3.50).</p><p><strong>Conclusion: </strong>The study demonstrates a positive reception of acupuncture in dental settings, with moderate to high levels of patient acceptance and satisfaction. These findings suggest that acupuncture could be a valuable adjunctive therapy in comprehensive dental care, particularly for pain management and anxiety reduction. However, further research is needed to fully establish its efficacy across various dental procedures.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3628-S3630"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Quality of Life in Patients with Chronic Oral Mucosal Diseases: A Questionnaire-Based Study.","authors":"Ajay Kajla, Manoj Meena, Mohit Sareen, Omprakash Kumawat, Kamal Kishor Saini, Anil Gulia, Kshitij Bhardwaj","doi":"10.4103/jpbs.jpbs_1421_24","DOIUrl":"10.4103/jpbs.jpbs_1421_24","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the quality of life (QoL) of patients who suffer from long-term oral mucosal disorders.</p><p><strong>Methods: </strong>A total of 200 individuals with chronic oral mucosal diseases (COMDs) were included. The QoL results were assessed using the Chronic Oral Mucosal Diseases Questionnaire (COMDQ). Of the 200 patients who were enrolled, 125 (61.5%) were men and 77 (38.1%) were women. Oral ulcers accounted for 77 (38.1%) of all COMDs, whereas radiation or chemotherapy ulcers accounted for just 6 (3.0%). The COMDQ had a mean score of 19.9 overall. The domain score of pain and function had the highest mean score of 13.2, and the total evaluation score was satisfactory with a range of 49%. The QoL was more negatively impacted by mouth opening reduction and oral ulcers than by the other COMD categories.</p><p><strong>Conclusion: </strong>A longitudinal study design may be used in future research to look at how drugs affect COMD patients' QoL over time.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3996-S3998"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}