Saloni Verma, Annuroopa Mahapatra, Kavita Gupta, Harisha Dewan, Minu Raju, D Anupama Prasad
{"title":"Assessment of the Antibacterial Properties and Cytocompatibility of Implant Coatings Incorporating Antimicrobial Agents: An <i>In vitro</i> Study.","authors":"Saloni Verma, Annuroopa Mahapatra, Kavita Gupta, Harisha Dewan, Minu Raju, D Anupama Prasad","doi":"10.4103/jpbs.jpbs_1104_24","DOIUrl":"10.4103/jpbs.jpbs_1104_24","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluates the antibacterial efficacy and cytocompatibility of titanium implants coated with silver, chitosan, and antibiotics.</p><p><strong>Materials and methods: </strong>Antibacterial properties were tested using inhibition zones against <i>S. aureus, E. coli</i>, and <i>P. aeruginosa</i>. The cytocompatibility was assessed through cell viability, adhesion, and proliferation by using human osteoblast-like cells (MG-63). Statistical analysis was performed using ANOVA and Tukey's HSD test.</p><p><strong>Results: </strong>Antibiotics showed the highest antibacterial activity. Silver reduced cell viability, adhesion, and proliferation, while chitosan balanced antibacterial efficacy and biocompatibility. Time-dependent viability assays indicated consistent reduction for silver-treated cells.</p><p><strong>Conclusion: </strong>Silver, chitosan, and antibiotics are effective against implant-related pathogens, but their cytocompatibility varies.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3607-S3609"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeyabarathi Krishnasamy, T Jayadeepa, Rajitha S Rajam, Senthil Purushothaman, K Mohanraj, Lingaraj Chitra, Sivakumar Chinnusamy
{"title":"A Study to Evaluate the Effectiveness of Self-Instructional Module Regarding Expression and Storage of Breast Milk among Working Mothers at Semmanichettipalayam Coimbatore.","authors":"Jeyabarathi Krishnasamy, T Jayadeepa, Rajitha S Rajam, Senthil Purushothaman, K Mohanraj, Lingaraj Chitra, Sivakumar Chinnusamy","doi":"10.4103/jpbs.jpbs_1046_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_1046_24","url":null,"abstract":"<p><strong>Introduction: </strong>Breast milk is the optimal food for infants, supporting their physical and emotional development. Breastfeeding should begin within an hour of birth.</p><p><strong>Study objectives: </strong>a) Assess knowledge of breast milk expression and storage among working mothers. b) Evaluate practices related to expression and storage. c) Provide a self-instructional module on expressed breast milk. d) Measure the module's effectiveness. e) Analyze the association between knowledge, practice, and selected demographic variables.</p><p><strong>Methodology: </strong>An experimental study with 40 working mothers selected via convenience sampling. A structured questionnaire assessed knowledge and practices.</p><p><strong>Results: </strong>Descriptive statistics were used, yielding a \"t\" value of 9.35. Over 15 days, questionnaires were administered to 3 participants daily, with posttests and the instructional module provided after 15 days.</p><p><strong>Conclusion: </strong>The study showed a significant improvement in knowledge and practices after the self-instructional module was provided.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3562-S3564"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11804991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of the Effectiveness of Video-Assisted Teaching on Knowledge Regarding the Management of Post-Hemodialysis Fatigue among Patients Attending Hemodialysis.","authors":"Pratiksha Munjewar, Ranjana Sharma, Gauri Chandrashekhar Mahakalkar, Archana Dhok, Gaurav Jaiswal","doi":"10.4103/jpbs.jpbs_916_24","DOIUrl":"10.4103/jpbs.jpbs_916_24","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease (CKD) is a global health issue, affecting 13.4% of the population. Many CKD patients progress to end-stage renal disease, necessitating lifelong renal replacement therapy like dialysis. Hemodialysis significantly alters patients' lifestyles, causing social isolation, work-life changes, financial strain, and family role shifts. These challenges lead to fatigue, pain, depression, and sleep disturbances, severely impacting patients' quality of life and daily activities. Among these symptoms, fatigue is one of the most common and disruptive.</p><p><strong>Aim: </strong>To assess the effectiveness of video-assisted teaching on knowledge regarding the management of post-hemodialysis fatigue among patients attending hemodialysis.</p><p><strong>Material and method: </strong>This study was based on a quantitative research approach and one group pretest and post-test research design. This study includes 200 patients attending hemodialysis from Acharya Vinoba Bhave Rural Hospital Wardha with the nonprobability convenience sampling technique. A questionnaire was used to assess the knowledge of the patient.</p><p><strong>Result: </strong>After the educational program, the knowledge score improved significantly. The poor category decreased to 50 participants (25.0%), while the average category dropped to participants (5.0%). The good category increased substantially to 110 participants (55.5%), and 30 participants (15.0%) achieved an excellent level of knowledge.</p><p><strong>Conclusion: </strong>Results suggest that after applying intervention, the knowledge regarding post-hemodialysis fatigue is increased in patients attending hemodialysis.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3452-S3455"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Evaluation of Survival Against Fracture in Premolars Treated Endodontically for Cervical Lesions and Restored with Resin and Crowns.","authors":"Punita Singh, Rameet Sandhu, Pinky Singh, Sahana Karthik, Shobha Bharti, Manish Bhargava","doi":"10.4103/jpbs.jpbs_1017_24","DOIUrl":"10.4103/jpbs.jpbs_1017_24","url":null,"abstract":"<p><strong>Background: </strong>For endodontic treatment, coronal restoration is crucial in preventing coronal leakage and protecting against fractures in the remaining tooth structure.</p><p><strong>Aim: </strong>To evaluate the effect of the restorations in endodontically treated teeth on survival against fracture in premolars having cervical lesions to identify the prognostic factors depicting the fracture.</p><p><strong>Methods: </strong>Endodontically treated premolars had exposed cervical lesions, and crowns or resin composites were assessed. In the included premolars, the fracture presence was noted along with the prognostic factors associated. The data recorded were analyzed using applicable statistical tests and considering <i>P</i> < 0.05 as the significance level.</p><p><strong>Results: </strong>There was no statistically significant difference in the rates of survival against breakage among teeth replaced with resin composites or crowns, and a decrease in crestal bone in the middle third of the root for fracture was identified as the most important predictor (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>In endodontically treated premolar and exposed cervical lesions, a high survival against fracture rate was associated with resin composite restoration compared to the crowns and premolars with crestal bone loss till the middle-third of the root have a high risk of fracture.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3959-S3961"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of <i>Dadru Kushtha</i> (Tenia corporis)-A Case Report.","authors":"Trupti Thakre, Sourabh G Deshmukh, Neha Chavhan","doi":"10.4103/jpbs.jpbs_889_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_889_24","url":null,"abstract":"<p><p>Dadru is one of the Kapha-Pitta Pradhana Twak Vikara. It is a chronic disease in which Tridosha are involved so <i>Rakta shodhak</i> and <i>Tridoshaghna</i> along with <i>Kushtaghna Chikitsa</i> give better relief in <i>Dadru</i>. A 32-year-old male patient approached the outpatient department (OPD) of Mahatma Gandhi Ayurveda Hospital, Salod, Wardha, Maharashtra, with a chief complaint of round reddish patches over the axilla with severe <i>Kandu</i> (Itching), <i>Daha</i> (burning sensation), elevated circular lesions, and <i>Raag</i> (erythema). After 15 days of treatment, the patient got relief from all the symptoms by taking proper medicines like <i>Gandhak Rasayan, Panchatikta ghrita</i>, 777 oil, and fungiwin cream. Due to <i>Kushtaghna</i> and the immunity booster properties of drugs, the present case study revealed the efficacy of <i>Ayurveda</i> by <i>Shaman Chikitsa</i> for 15 days in managing <i>Dadru</i>.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S4152-S4154"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suprasidh Suprakasam, Reshma S Kakkachi Parambil, Krishnan Hari, Priya Viswanathan, Irene Abraham, Ebin T Mathai
{"title":"Comparative Long-Term Outcomes of Formocresol, Mineral Trioxide Aggregate, and Laser Pulpotomy Techniques in Primary Teeth.","authors":"Suprasidh Suprakasam, Reshma S Kakkachi Parambil, Krishnan Hari, Priya Viswanathan, Irene Abraham, Ebin T Mathai","doi":"10.4103/jpbs.jpbs_711_24","DOIUrl":"10.4103/jpbs.jpbs_711_24","url":null,"abstract":"<p><strong>Background: </strong>Pulpotomy is a common dental procedure used to treat extensively decayed primary teeth, aiming to preserve the vitality and function of the remaining pulp tissue. Various pulpotomy techniques and materials have been developed, but their long-term outcomes in terms of success rates and complications remain a subject of ongoing research.</p><p><strong>Materials and methods: </strong>A total of 180 primary molars from children aged 4-8 years were treated using three different pulpotomy techniques: Formocresol (<i>n</i> = 60), Mineral Trioxide Aggregate (MTA) (<i>n</i> = 60), and Laser Pulpotomy (<i>n</i> = 60). Follow-ups were conducted at 6, 12, and 24 months posttreatment to evaluate clinical and radiographic success. Clinical success was defined by the absence of pain, swelling, and mobility, while radiographic success was indicated by the lack of internal resorption, furcation radiolucency, and periapical pathology.</p><p><strong>Results: </strong>At the 24-month follow-up, the clinical success rates were 80% for Formocresol, 95% for MTA, and 90% for Laser Pulpotomy. Radiographic success rates were 75% for Formocresol, 92% for MTA, and 88% for Laser Pulpotomy. MTA demonstrated the highest overall success rates, with statistically significant differences compared to Formocresol (<i>P</i> < 0.01) but not Laser Pulpotomy (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>Mineral Trioxide Aggregate (MTA) showed superior long-term outcomes compared to Formocresol and comparable results to Laser Pulpotomy for the treatment of primary teeth.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3233-S3235"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahtesham A Qurishi, Mohammed S Al Dira, Amal H Sholan, Shahad E Abzoah, Mahdi A Hakami, Emad Malhan, Shahad M Moafa
{"title":"Effect of Different Pediatric Medications on RMGIC: A Comparative Study.","authors":"Ahtesham A Qurishi, Mohammed S Al Dira, Amal H Sholan, Shahad E Abzoah, Mahdi A Hakami, Emad Malhan, Shahad M Moafa","doi":"10.4103/jpbs.jpbs_688_24","DOIUrl":"10.4103/jpbs.jpbs_688_24","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigates the impact of commonly prescribed pediatric medications on resin-modified glass ionomer cement (RMGIC), which is widely used in pediatric dentistry in India. The interaction between these medications and RMGIC could affect the material's durability and effectiveness.</p><p><strong>Methodology: </strong>Sixty RMGIC specimens were divided into five groups, each exposed to different pediatric medications: antibiotic syrup, antipyretic syrup, vitamin syrup, antitussive syrup, and distilled water (control). Microhardness and surface roughness were measured before and after a 14-day immersion period. Statistical analysis was conducted using one-way ANOVA and post-hoc Tukey's test.</p><p><strong>Results: </strong>All pediatric medications significantly affected RMGIC, with antitussive syrup showing the most substantial impact. Microhardness decreased by up to 18.40%, and surface roughness increased by up to 21.40%. The control group showed no significant changes.</p><p><strong>Conclusion: </strong>Pediatric medications, particularly those with acidic properties, compromise the durability of RMGIC. Further research is needed to develop more resistant materials or protective measures.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3185-S3187"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G R Ishwarya Dhevi, Ponnudurai Arangannal, J Jeevarathan
{"title":"Comparative Analysis of Cytotoxicity and Odontogenic Differentiation of Novel Bioceramic Material on Human Dental Pulp Stem Cells - An <i>In Vitro</i> Study.","authors":"G R Ishwarya Dhevi, Ponnudurai Arangannal, J Jeevarathan","doi":"10.4103/jpbs.jpbs_1078_24","DOIUrl":"10.4103/jpbs.jpbs_1078_24","url":null,"abstract":"<p><strong>Background and objective: </strong>Bioceramic materials have revolutionized the field of endodontics by successfully transforming the outcomes of pulp therapies. Novel biomaterials are evolving by modifying the conventional mineral trioxide aggregate (MTA) to overcome their existing limitations, the major ones being prolonged setting and cytotoxic radiopacifiers. Dental white portland cement (DWPC) is a novel formulated bioceramic material introduced as an enhanced MTA alternative. This in vitro study aims to investigate the cytotoxicity and odontogenic differentiation of novel formulation DWPC with MTA Angelus, Biodentin (BD) and white portland cement (WPC) on human dental pulp stem cells (HDPSCs).</p><p><strong>Materials and methods: </strong>HDPSCs were cultured in Dulbecco's modified eagle's medium (DMEM) with fetal bovine serum (FBS) and antibiotics at 37°C, 90% humidity in a 5% CO<sub>2</sub> incubator. Experimental samples were prepared as disks. The viability of HDPSCs was measured by Mosmann's tetrazolium toxicity (MTT) assay, and odontogenic potential was assessed using alkaline phosphatase (ALP) activity at 24 hours, 7-, 14-, and 21-day intervals. The mean and standard deviations were statistically analyzed by one-way ANOVA and <i>post hoc</i> Scheffe tests using IBM SPSS Software (IBM statistical package for social sciences) - Version 24.0 with a significance level set as <i>P</i> < 0.05.</p><p><strong>Results: </strong>All four groups tested using MTT assay showed no toxicity and possess odontogenic potential in all the experimental durations. Experimental group DWPC presented with the highest mean cell viability and ALP activity at all intervals followed by WPC, MTA, and BD (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>DWPC presented good bioactivity in terms of cell viability and ALP activity. Thus, DWPC could be a promising endodontic material. However, further research is warranted to explore the clinical applicability.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3951-S3955"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E M Arshad Ali, Kiran Dodani, Ankur Singh Rajpoot, Pallavi Goswami, Varsha Choubey, Aanchal Gupta
{"title":"Effect of Omega-3 Fatty Acid Supplementation on Periodontal Inflammation and Pocket Depth Reduction.","authors":"E M Arshad Ali, Kiran Dodani, Ankur Singh Rajpoot, Pallavi Goswami, Varsha Choubey, Aanchal Gupta","doi":"10.4103/jpbs.jpbs_1173_24","DOIUrl":"10.4103/jpbs.jpbs_1173_24","url":null,"abstract":"<p><strong>Background: </strong>Chronic inflammation of the tooth's supporting tissues is known as periodontal disease. It causes pockets to develop, attachments to break, and eventually the loss of teeth. Because of their well-known anti-inflammatory qualities, omega-3 fatty acids have been recommended as an additional therapy for periodontal inflammation.</p><p><strong>Materials and methods: </strong>A randomized controlled study of 60 individuals suffering from persistent periodontitis was carried out. Two groups of participants were randomly assigned: The test group (n = 30) got conventional periodontal treatment with omega-3 fatty acid supplementation (1000 mg/day), while the control group (n = 30) received normal periodontal therapy alone. Measurements of periodontal parameters were made at baseline, 3 months, and 6 months after therapy, including bleeding on probing (BOP) and pocket depth. Paired t-tests and analysis of variance were used in the statistical analysis to determine the significance of the group differences.</p><p><strong>Results: </strong>Participants in the test group showed a greater reduction in probing pocket depth (PPD) and BOP at both 3 and 6 months. Specifically, the mean PPD decreased from 5.4 ± 0.7 mm to 3.0 ± 0.4 mm, and BOP reduced from 71.2 ± 14.5% to 28.3 ± 9.2% in the test group, with both outcomes showing statistically significant differences compared to the control group (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>In individuals with chronic periodontitis, omega-3 fatty acid supplementation dramatically improves the decrease of periodontal pocket depth and inflammation when administered as an adjuvant to regular periodontal treatment.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3670-S3672"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shailaben Chaudhary, Shobha Fernandes, Hardikkumar B Patel, Priya Mishra, Nishan R Patel, Yash Bafna, Miral Mehta
{"title":"Comparison of Resin Infiltrant and Sealants on Pre-Cavitated Lesions in Primary Teeth: A Quantitative Analysis Using Atomic Absorption Spectrophotometry.","authors":"Shailaben Chaudhary, Shobha Fernandes, Hardikkumar B Patel, Priya Mishra, Nishan R Patel, Yash Bafna, Miral Mehta","doi":"10.4103/jpbs.jpbs_1329_24","DOIUrl":"10.4103/jpbs.jpbs_1329_24","url":null,"abstract":"<p><strong>Aim: </strong>This study was conducted to analyze the effects of sealants and resin infiltrant on pre-cavitated lesions in primary teeth (AAS) using an atomic absorption spectrophotometer.</p><p><strong>Material and method: </strong>Forty freshly extracted intact human primary molars were used for the study. All the specimens were then divided into four groups of ten specimens. These groups are treated differently. The specimens were stored in artificial saliva throughout the study. The AAS was then used to assess the calcium dissolution of artificial saliva.</p><p><strong>Result: </strong>A comparison of Group III and Group IV established a statistically significant difference found in the amount of calcium dissolution in artificial saliva. Group III showed lesser calcium dissolution from enamel compared to Group IV in artificial saliva.</p><p><strong>Conclusion: </strong>Resin infiltration showed more resistance to the release of calcium from enamel as compared to Clinpro Sealant in artificial saliva.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 4","pages":"S3874-S3876"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}