在冰雹人群中使用减充血剂的流行程度评估。

IF 0.9 Q4 PHARMACOLOGY & PHARMACY
Journal of pharmacy & bioallied sciences Pub Date : 2025-06-01 Epub Date: 2025-06-18 DOI:10.4103/jpbs.jpbs_364_25
Farida Habib Khan, Abdullah D Alotaibi, Amal Daher Alshammari, Mohammed Alateeq, Muath Alshmmari, Read Alharbi, Rakhi Issrani
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引用次数: 0

摘要

背景:鼻减充血剂被广泛用于缓解由变应性鼻炎、鼻窦炎和普通感冒引起的鼻塞。这些药物的作用是收缩鼻血管,减少肿胀,改善气流。尽管它们有效,但使用不当可能导致不良反应,包括反弹充血和心血管并发症。材料与方法:采用结构化问卷对沙特阿拉伯哈伊尔300名成年居民进行横断面研究。参与者通过简单随机抽样的方式选择。问卷评估了减充血剂的使用频率、首选减充血剂的类型、使用原因以及对潜在健康风险的认识。采用描述性统计对数据进行分析,并采用卡方检验评估人口统计学因素与减充血剂使用之间的关系。结果:在参与者中,65%的人报告定期使用鼻腔减充血剂,45%的人更喜欢使用局部减充血剂(如羟甲基唑啉),55%的人使用口服减充血剂(如伪麻黄碱)。大多数人(72%)报告在没有医疗咨询的情况下自行用药,而60%的人不知道反弹充血的风险。有变应性鼻炎或鼻窦炎病史的患者使用减充血药的频率显著高于其他患者(P < 0.05)。此外,30%的使用者出现了副作用,包括心率加快(15%)和鼻腔刺激(10%)。结论:该研究强调了冰雹患者使用减充血剂的高发率,这在很大程度上受环境因素和公众对潜在风险缺乏认识的影响。研究结果强调需要有针对性的公共卫生运动和药剂师主导的干预措施,以促进更安全的使用方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of the Prevalence of the Use of Nasal Decongestants Among Hail Population.

Background: Nasal decongestants are widely used to relieve nasal congestion caused by conditions such as allergic rhinitis, sinusitis, and the common cold. These medications function by constricting nasal blood vessels, reducing swelling, and improving airflow. Despite their effectiveness, improper use can result in adverse effects, including rebound congestion and cardiovascular complications.

Materials and methods: A cross-sectional study was conducted among 300 adult residents of Hail, Saudi Arabia, using a structured questionnaire. Participants were selected through simple random sampling. The questionnaire assessed the frequency of nasal decongestant use, types of decongestants preferred, reasons for use, and awareness regarding potential health risks. Data were analyzed using descriptive statistics, and Chi-square tests were performed to evaluate associations between demographic factors and decongestant use.

Results: Among the participants, 65% reported regular nasal decongestant use, with 45% preferring topical decongestants (e.g., oxymetazoline) and 55% using oral formulations (e.g., pseudoephedrine). The majority (72%) reported self-medicating without medical consultation, while 60% were unaware of the risk of rebound congestion. Individuals with a history of allergic rhinitis or sinusitis were significantly more likely to use nasal decongestants frequently (P < 0.05). Additionally, 30% of users experienced side effects, including increased heart rate (15%) and nasal irritation (10%).

Conclusion: The study highlights a high prevalence of nasal decongestant use in Hail, largely influenced by environmental factors and a lack of public awareness regarding potential risks. The findings underscore the need for targeted public health campaigns and pharmacist-led interventions to promote safer usage practices.

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