N. Ikeda, S. Yachi, M. Takeyama, Y. Nishimoto, I. Tsujino, J. Nakamura, N. Yamamoto, Hiroko Nakata, S. Ikeda, Michihisa Umetsu, S. Aikawa, H. Hayashi, H. Satokawa, Yoshinori Okuno, Eriko Iwata, Yoshito Ogihara, A. Kondo, Takehisa Iwai, N. Yamada, Tomohiro Ogawa, Takao Kobayashi, M. Mo, Y. Yamashita
{"title":"D-Dimer Values and Venous Thromboembolism in Patients With COVID-19 in Japan ― From the CLOT-COVID Study ―","authors":"N. Ikeda, S. Yachi, M. Takeyama, Y. Nishimoto, I. Tsujino, J. Nakamura, N. Yamamoto, Hiroko Nakata, S. Ikeda, Michihisa Umetsu, S. Aikawa, H. Hayashi, H. Satokawa, Yoshinori Okuno, Eriko Iwata, Yoshito Ogihara, A. Kondo, Takehisa Iwai, N. Yamada, Tomohiro Ogawa, Takao Kobayashi, M. Mo, Y. Yamashita","doi":"10.1253/circrep.CR-22-0022","DOIUrl":"https://doi.org/10.1253/circrep.CR-22-0022","url":null,"abstract":"Background: To date, there are no large-scale data on the association between D-dimer levels at admission and the occurrence of venous thromboembolism (VTE) in Japanese patients with coronavirus disease 2019 (COVID-19). Methods and Results: The CLOT-COVID study was a retrospective, multicenter cohort study enrolling consecutive hospitalized patients with COVID-19 across 16 centers in Japan from April 2021 to September 2021. Among 2,894 enrolled patients, 2,771 (96%) had D-dimer levels measured at admission. Patients were divided into 3 groups based on tertiles of D-dimer levels at admission (1st tertile, D-dimer ≤0.5 μg/mL, n=949; 2nd tertile, D-dimer 0.51–1.09 μg/mL, n=894; 3rd tertile, D-dimer ≥1.1 μg/mL, n=928). The higher the tertile group, the more severe the COVID-19 status at admission. The incidence of VTE during hospitalization was highest in the 3rd tertile group (1st tertile, 0.3%; 2nd tertile, 0.3%; 3rd tertile, 3.6%; P<0.001). Even after adjusting for confounders in the multivariable logistic regression model, the higher D-dimer levels in the 3rd tertile (≥1.1 μg/mL) were independently associated with a higher risk of VTE during hospitalization (adjusted odds ratio 4.83 [95% confidence interval 1.93–12.11; P<0.001]; reference=1st tertile). Conclusions: Higher D-dimer levels at admission were associated with a higher risk of VTE events during hospitalization in Japanese patients with COVID-19. This could be helpful in determining patient-specific anticoagulation management strategies for COVID-19 in Japan.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"40 1","pages":"215 - 221"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86525523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Hirashiki, A. Shimizu, K. Nomoto, M. Kokubo, Noriyuki Suzuki, H. Arai
{"title":"Systematic Review of the Effectiveness of Community Intervention and Health Promotion Programs for the Prevention of Non-Communicable Diseases in Japan and Other East and Southeast Asian Countries","authors":"A. Hirashiki, A. Shimizu, K. Nomoto, M. Kokubo, Noriyuki Suzuki, H. Arai","doi":"10.1253/circrep.cr-21-0165","DOIUrl":"https://doi.org/10.1253/circrep.cr-21-0165","url":null,"abstract":"Background: Non-communicable diseases (NCDs) are the leading cause of death worldwide. However, current evidence regarding the efficacy and cost-effectiveness of community intervention and health promotion programs for NCDs, specifically hypertension, obesity, diabetes, and dyslipidemia, in East and Southeast Asia has not yet been systematically reviewed. We systematically reviewed the literature from East and Southeast Asian countries to answer 2 clinical questions: (1) do health promotion programs for hypertension, obesity, diabetes, and dyslipidemia reduce cardiovascular events and mortality; and (2) are these programs cost-effective? Methods and Results: Electronic literature searches were performed across Medline, Cochrane Library, and Ichushi using key words and relevant subject headings related to randomized controlled trials, comparative studies, quasi-experimental studies, or propensity score matching that met eligibility criteria that were defined for each question. In all, 3,389 records were identified, of which 12 full-text articles were reviewed. Three papers were from Japan, 7 were from China/Hong Kong Special Administrative Region, and 2 were from South Korea. None were from Southeast Asia. Four papers examined the effect of community intervention or health promotion on the incidence of cardiovascular events or mortality. Eight studies examined the cost-effectiveness of interventions. Conclusions: The literature review revealed that community intervention and health promotion programs for the control of NCDs are a cost-effective means of reducing cardiovascular events and mortality in East Asian countries.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"37 1","pages":"149 - 157"},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84732952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Kato, Taka-aki Matsuyama, Masaya Fujishiro, Mari Hashimoto, H. Sone, Toshiko Onizuka-Yamochi
{"title":"Local Variation and Age-Related Change in Atrial and Ventricular Myocardial Contiguity at the Atrioventricular Junction in Human Hearts","authors":"Y. Kato, Taka-aki Matsuyama, Masaya Fujishiro, Mari Hashimoto, H. Sone, Toshiko Onizuka-Yamochi","doi":"10.1253/circrep.cr-22-0013","DOIUrl":"https://doi.org/10.1253/circrep.cr-22-0013","url":null,"abstract":"Background: We explored the histologic patterns of and age-related changes in atrial and ventricular myocardial contiguity at the left and right atrioventricular (AV) junction that could be a target site for catheter ablation. Methods and Results: Twenty-three structurally normal adult hearts obtained at autopsy were studied. The 2 AV annuli were divided into 13 clinically recognized portions in which we measured distance between the atrial and ventricular myocardium at the AV junction. Overall, measured distance was less on the right than left side (mean [±SD] 0.74±0.59 vs. 1.15±0.78 mm, respectively), and distance increased gradually with age. The gap was smallest at the anterolateral portion on the right side and posterolateral portion on the left side. Three specific features were noted, namely extension of the ventricular myocardium (coarse trabeculae) towards the atrium on the right side of the AV junction, extension of the atrial myocardium onto the AV valve leaflets, and a collection of small myocardial cells, perhaps including specialized cells, in the right anterolateral portion. No concealed AV muscular connections were found. Conclusions: Contiguity and separation of the myocardium at the AV junction have specific patterns, and myocardial proximity is influenced by age. These histologic features of the AV junction may prove to be informative for catheter ablation of tachyarrhythmias related to the AV junction.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 1","pages":"158 - 165"},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84551416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fumika Aniya, A. Sakima, M. Takakura, K. Shirai, Masumi Shimabukuro, H. Todoriki, K. Okumura, K. Takemura, Noboru Kinjyo, Y. Ohya
{"title":"Effect of Nutrition Education on the Vegetable Intake of Residents in Okinawa","authors":"Fumika Aniya, A. Sakima, M. Takakura, K. Shirai, Masumi Shimabukuro, H. Todoriki, K. Okumura, K. Takemura, Noboru Kinjyo, Y. Ohya","doi":"10.1253/circrep.CR-21-0152","DOIUrl":"https://doi.org/10.1253/circrep.CR-21-0152","url":null,"abstract":"Background: Increasing vegetable intake is recommended for promoting health in communities. This study investigated the effects of nutrition education on vegetable intake and the factors associated with changes in vegetable intake among residents of Okinawa. Methods and Results: Subjects (n=1,345; mean [±SD] age 56.8±14.6 years; 40.5% male) were recruited from among local residents participating in the Yui Kenko Project. Subjects completed the brief-type self-administered diet history questionnaire (BDHQ) and questionnaires on socioeconomic demographics and social capital. Subjects were divided into 2 groups according to residential area, namely south Okinawa (n=679), where local health promotion activities have been undertaken since the early 2000s, and central Okinawa (n=666). Survey results were fed back to each subject, and health lectures were then conducted at local community centers. After 1 year, the BDHQ was repeated to investigate changes in vegetable and nutritional parameters. After the intervention, residents of south Okinawa increased their crude and energy-adjusted vegetable intake (P<0.05), whereas residents of central Okinawa showed decreased vegetable intake (P<0.05). Univariable and multivariable regression models indicated that, in south Okinawa, participation in local health promotion activities and agreement with general trust were positively correlated with changes in energy-adjusted vegetable intake, whereas in central Okinawa no correlations were observed. Conclusions: The status of social capital should be taken into account when implementing initiatives to increase vegetable intake in communities.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"42 1","pages":"131 - 144"},"PeriodicalIF":0.0,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87394631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Yamaguchi, T. Matoba, M. Kikuchi, Y. Minami, S. Kojima, H. Hanada, T. Mano, T. Nakashima, Katsutaka Hashiba, Takeshi Yamamoto, A. Tanaka, K. Matsuo, Naoki Nakayama, Osamu Nomura, Y. Tahara, H. Nonogi
{"title":"Effects of Door-In to Door-Out Time on Mortality Among ST-Segment Elevation Myocardial Infarction Patients Transferred for Primary Percutaneous Coronary Intervention ― Systematic Review and Meta-Analysis ―","authors":"J. Yamaguchi, T. Matoba, M. Kikuchi, Y. Minami, S. Kojima, H. Hanada, T. Mano, T. Nakashima, Katsutaka Hashiba, Takeshi Yamamoto, A. Tanaka, K. Matsuo, Naoki Nakayama, Osamu Nomura, Y. Tahara, H. Nonogi","doi":"10.1253/circrep.CR-21-0160","DOIUrl":"https://doi.org/10.1253/circrep.CR-21-0160","url":null,"abstract":"Background: Primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) is now widely accepted. Recent guidelines have focused on total ischemic time, because shorter total ischemic time is associated with a more favorable prognosis. The door-in to door-out (DIDO) time, defined as time from arrival at a non-PCI-capable hospital to leaving for a PCI-capable hospital, may affect STEMI patient prognosis. However, a relevant meta-analysis is lacking. Methods and Results: We searched PubMed for clinical studies comparing short-term (30-day and in-hospital) mortality rates of STEMI patients undergoing primary PCI with DIDO times of ≤30 vs. >30 min. Two investigators independently screened the search results and extracted the data. Random effects estimators with weights calculated by the inverse variance method were used to determine pooled risk ratios. The search retrieved 1,260 studies; of these, 2 retrospective cohort studies (15,596 patients) were analyzed. In the DIDO time ≤30 and >30 min groups, the primary endpoint (i.e., in-hospital or 30-day mortality) occurred for 51 of 1,794 (2.8%) and 831 of 13,802 (6.0%) patients, respectively. The incidence of the primary endpoint was significantly lower in the DIDO time ≤30 min group (odds ratio 0.45; 95% confidence interval 0.34–0.60). Conclusions: Our findings suggest that a DIDO time ≤30 min is associated with a lower short-term mortality rate. However, further larger systematic reviews and meta-analyses are needed to validate our findings.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 1","pages":"109 - 115"},"PeriodicalIF":0.0,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87180565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Different Positions of the Impella Device Between the Axillary and Femoral Approaches","authors":"Y. Nishimoto, K. Okayama, M. Toma, Yukihito Sato","doi":"10.1253/circrep.cr-21-0164","DOIUrl":"https://doi.org/10.1253/circrep.cr-21-0164","url":null,"abstract":"Received January 6, 2022; accepted February 8, 2022; J-STAGE Advance Publication released online February 19, 2022 Time for primary review: 33 days Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki (Y.N., M.T., Y.S.); Department of Cardiology, Osaka University Graduate School of Medicine, Osaka (K.O.), Japan Mailing address: Yuji Nishimoto, MD, Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, 2-17-77 Higashinaniwa-cho, Amagasaki 660-8550, Japan. E-mail: yuji.nishimoto@gmail.com All rights are reserved to the Japanese Circulation Society. For permissions, please e-mail: cr@j-circ.or.jp ISSN-2434-0790 Different Positions of the Impella Device Between the Axillary and Femoral Approaches","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"51 1","pages":"183 - 184"},"PeriodicalIF":0.0,"publicationDate":"2022-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81645318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Hirashiki, A. Shimizu, Noriyuki Suzuki, K. Nomoto, M. Kokubo, Kakeru Hashimoto, Kenji Sato, I. Kondo, T. Murohara, H. Arai
{"title":"Composite Biomarkers for Assessing Frailty Status in Stable Older Adults With Cardiovascular Disease","authors":"A. Hirashiki, A. Shimizu, Noriyuki Suzuki, K. Nomoto, M. Kokubo, Kakeru Hashimoto, Kenji Sato, I. Kondo, T. Murohara, H. Arai","doi":"10.1253/circrep.CR-21-0143","DOIUrl":"https://doi.org/10.1253/circrep.CR-21-0143","url":null,"abstract":"Background: The relationship between frailty status and laboratory measurements in cardiovascular disease (CVD) remains unclear. We investigated which laboratory measurements indicated frailty in stable older CVD patients. Methods and Results: One-hundred thirty-eight stable older CVD patients were evaluated by laboratory measurements, with frailty assessed using the Kihon Checklist (KCL). Laboratory measurements were compared between frail and non-frail groups. Across the entire cohort, mean age was 81.7 years, mean left ventricular ejection fraction was 57.8%, and mean plasma B-type natriuretic peptide was 182 pg/mL. KCL scores were used to divide patients into non-frail (n=43; KCL <8) and frail (n=95; KCL ≥8) groups. Serum iron was significantly lower in the frail than non-frail group (mean [±SD] 61.2±30.3 vs. 89.5±26.1 μg/dL, respectively; P<0.001). Blood urea nitrogen (BUN; 27.3±16.5 vs. 19.7±8.2 mg/dL; P=0.013) and C-reactive protein (CRP; 1.05±1.99 vs. 0.15±0.21 mg/dL; P=0.004) were significantly higher in the frail than non-frail group. Multivariate analysis revealed that serum iron, CRP, and BUN were significant independent predictors of frailty (β=−0.069, 0.917, and 0.086, respectively). Conclusions: Frailty status was significantly associated with iron, CRP, and BUN in stable older CVD patients. Composite biomarkers (inflammation, iron deficiency, and renal perfusion) may be useful for assessing frailty in these patients.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"24 1","pages":"123 - 130"},"PeriodicalIF":0.0,"publicationDate":"2022-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89135559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nobuaki Itoh, M. Maruyama, I. Tsuboi, Tsuyoshi Nohara, S. Ishihara, W. Shimizu
{"title":"Arrhythmogenic Triggers of Atrial Fibrillation Arising From the Common Trunk of the Inferior Pulmonary Veins","authors":"Nobuaki Itoh, M. Maruyama, I. Tsuboi, Tsuyoshi Nohara, S. Ishihara, W. Shimizu","doi":"10.1253/circrep.CR-21-0154","DOIUrl":"https://doi.org/10.1253/circrep.CR-21-0154","url":null,"abstract":"Received January 10, 2022; accepted January 11, 2022; J-STAGE Advance Publication released online January 26, 2022 Time for primary review: 1 day Department of Cardiovascular Medicine, Nippon Medical School Musashi-Kosugi Hospital, Kawasaki (N.I., M.M., I.T., T.N., S.I.); Department of Cardiovascular Medicine, Nippon Medical School, Tokyo (W.S.), Japan Mailing address: Mitsunori Maruyama, MD, PhD, Department of Cardiovascular Medicine, Nippon Medical School Musashi-Kosugi Hospital, 1-383 Kosugi-machi, Nakahara-ku, Kawasaki 211-8533, Japan. E-mail: maru@nms.ac.jp All rights are reserved to the Japanese Circulation Society. For permissions, please e-mail: cr@j-circ.or.jp ISSN-2434-0790 Arrhythmogenic Triggers of Atrial Fibrillation Arising From the Common Trunk of the Inferior Pulmonary Veins","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"1 1","pages":"147 - 148"},"PeriodicalIF":0.0,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72676501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masataka Suzuki, Yu Izawa, T. Toba, A. Kono, K. Hirata
{"title":"Late Iodine Enhancement and Extracellular Volume Fraction in Cardiac Amyloidosis by Computed Tomography","authors":"Masataka Suzuki, Yu Izawa, T. Toba, A. Kono, K. Hirata","doi":"10.1253/circrep.CR-21-0162","DOIUrl":"https://doi.org/10.1253/circrep.CR-21-0162","url":null,"abstract":"vated at 43% (Figure C,D). Cardiac computed tomography (CT) was performed using a 256-detector row scanner. Equilibrium phase imaging was acquired 5 min after injection of 100 mL of iodine contrast agent (370 mgI/mL). The ECV was measured with the subtraction method using the precontrast and equilibrium phase images. Cardiac CT showed no coronary artery stenosis. Equilibrium phase imaging showed late iodine enhancement co-located with LGE (Figure E,F). The ECV by CT was 44%, as high as on CMR (Figure G,H). Per histopathology, the patient had A 72-year-old man was referred to hospital because of abnormal ECG, showing poor R wave progression in the precordial leads. Transthoracic echocardiography demonstrated concentric left ventricular hypertrophy, and speckle tracking showed an apical-sparing pattern. Cardiac magnetic resonance imaging (CMR) revealed late gadolinium enhancement (LGE) in the entire subendocardium, which was transmurally exhibited in the hypertrophic septum (Figure A,B). The extracellular volume fraction (ECV) by T1 mapping was remarkably ele-","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"52 1","pages":"145 - 146"},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83166467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kyohei Marume, S. Ogata, Ryota Kaichi, M. Nakai, M. Ishii, Takayuki Mori, S. Komaki, Hiroaki Kusaka, Reiko Toida, Kazumasa Kurogi, Y. Iwanaga, Y. Miyamoto, N. Yamamoto
{"title":"Incidence Rate of Hospitalization for Heart Failure in a Japanese City ― An Updated Reference for Japan’s Aging Society ―","authors":"Kyohei Marume, S. Ogata, Ryota Kaichi, M. Nakai, M. Ishii, Takayuki Mori, S. Komaki, Hiroaki Kusaka, Reiko Toida, Kazumasa Kurogi, Y. Iwanaga, Y. Miyamoto, N. Yamamoto","doi":"10.1253/circrep.CR-21-0142","DOIUrl":"https://doi.org/10.1253/circrep.CR-21-0142","url":null,"abstract":"Background: The prevalence of heart failure (HF) is increasing in aging societies, such as Japan. The current incidence rate (IR) of HF hospitalization in Japan is unknown. Methods and Results: We conducted a regional population-based study assessing the IR of HF hospitalization in Nobeoka City. Data were collected over a period of 3 years from all patients with HF admitted for the first time to hospitals and clinics. 406 HF hospitalizations were registered (54% female; mean age 82 years). The IR of HF hospitalization was 129/100,000 person-years. The difference in the IR between women and men was not significant (131 vs. 127/100,000 person-years, respectively; P=0.767). The age-adjusted IR in the 2015 Japanese population was 105/100,000 person-years. According to 5-year age bands, the IR of HF hospitalization gradually increased up to 60–70 years of age, then increased rapidly in those aged ≥95 years for both sexes. The IR ratio compared with age <65 years was higher in women than men in each older age group. Conclusions: In this population-based study, the current IR of HF hospitalization in a region of Japan was higher than the IR from another study conducted in a different region in early 2000. By presenting detailed age-related data, the research findings will contribute to estimating the number of HF hospitalizations in other areas of Japan.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"8 1","pages":"116 - 122"},"PeriodicalIF":0.0,"publicationDate":"2022-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87780698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}