Circulation reports最新文献_第7页

Relationship Between Left Ventricular Ejection Fraction and Treatment Characteristics in Hospitalized Patients With Heart Failure　- A Japanese Database Analysis. 心力衰竭住院患者左心室射血分数与治疗特点的关系——日本数据库分析。

Circulation reports Pub Date : 2023-09-21 eCollection Date: 2023-10-10 DOI: 10.1253/circrep.CR-23-0066

Ichiro Umemura, Shunsuke Eguchi, Yohei Morita, Hironobu Mitani, Kazuma Iekushi, Takao Kato

{"title":"Relationship Between Left Ventricular Ejection Fraction and Treatment Characteristics in Hospitalized Patients With Heart Failure　- A Japanese Database Analysis.","authors":"Ichiro Umemura, Shunsuke Eguchi, Yohei Morita, Hironobu Mitani, Kazuma Iekushi, Takao Kato","doi":"10.1253/circrep.CR-23-0066","DOIUrl":"https://doi.org/10.1253/circrep.CR-23-0066","url":null,"abstract":"Background: Triple combination therapy with a renin-angiotensin system modulator, a β-blocker, and a mineralocorticoid receptor antagonist is currently recommended for patients with heart failure (HF) with reduced ejection fraction. However, there is limited evidence on the extent to which triple combination therapy is currently prescribed to patients at the time of discharge from hospital in Japan. Methods and Results: Japanese patients hospitalized for HF (n=3,582) were evaluated in subgroups defined by left ventricular ejection fraction (LVEF) using anonymized claims and electronic health record data. At discharge, triple combination therapy prescription rates were low (40.4%, 30.0%, 20.8%, 14.0%, and 12.5% for patients with LVEF <30%, 30-<40%, 40-<50%, 50-<60%, and ≥60%, respectively). Advanced age, lower levels of B-type natriuretic peptide, and renal impairment were all significantly associated with lower rates of triple combination therapy use in the overall population. There were no significant differences in rehospitalization rates between LVEF subgroups; however, triple combination therapy use was associated with a significantly reduced risk of rehospitalization for HF in patients with LVEF <30%, 30-<40%, and 40-<50%. Conclusions: The use of triple combination therapy was significantly associated with a lower risk of rehospitalization for HF within 1 year of discharge in patients with LVEF <30%, 30-<40%, and 40-<50%. However, patients were undertreated with triple combination therapy.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"5 10","pages":"392-402"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2f/09/circrep-5-392.PMC10561998.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiovascular Hospitalizations and Hospitalization Costs in Japan During the COVID-19 Pandemic. 新冠肺炎大流行期间日本心血管住院和住院费用。

Circulation reports Pub Date : 2023-09-16 eCollection Date: 2023-10-10 DOI: 10.1253/circrep.CR-23-0072

Tadafumi Sugimoto, Atsushi Mizuno, Daisuke Yoneoka, Shingo Matsumoto, Chisa Matsumoto, Yuya Matsue, Mari Ishida, Michikazu Nakai, Yoshitaka Iwanaga, Yoshihiro Miyamoto, Koichi Node

{"title":"Cardiovascular Hospitalizations and Hospitalization Costs in Japan During the COVID-19 Pandemic.","authors":"Tadafumi Sugimoto, Atsushi Mizuno, Daisuke Yoneoka, Shingo Matsumoto, Chisa Matsumoto, Yuya Matsue, Mari Ishida, Michikazu Nakai, Yoshitaka Iwanaga, Yoshihiro Miyamoto, Koichi Node","doi":"10.1253/circrep.CR-23-0072","DOIUrl":"10.1253/circrep.CR-23-0072","url":null,"abstract":"Background: During the COVID-19 pandemic, cardiovascular hospitalizations decreased and in-hospital mortality for ST-elevation myocardial infarction and heart failure increased. However, limited research has been conducted on hospitalization and mortality rates for cardiovascular disease (CVD) other than ischemic heart disease and heart failure. Methods and Results: We analyzed the records of 530 certified hospitals affiliated with the Japanese Circulation Society obtained from the nationwide JROAD-DPC database between April 2014 and March 2021. A quasi-Poisson regression model was used to predict the counterfactual number of hospitalizations for CVD treatment, assuming there was no pandemic. The observed number of inpatients compared with the predicted number in 2020 was 88.1% for acute CVD, 78% for surgeries or procedures, 77.2% for catheter ablation, and 68.5% for left ventricular assist devices. Furthermore, there was no significant change in in-hospital mortality, and the decrease in hospitalizations for catheter ablation and valvular heart disease constituted 47.6% of the total decrease in annual hospitalization costs during the COVID-19 pandemic. Conclusions: Cardiovascular hospitalizations decreased by more than 10% in 2020, and the number of patients scheduled for left ventricular assist device implantation decreased by over 30%. In addition, in response to the COVID-19 pandemic, annual cardiovascular hospitalization costs were reduced, largely attributed to decreased catheter ablation and valvular heart disease.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"5 10","pages":"381-391"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b2/a1/circrep-5-381.PMC10561996.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic Effect of HotBalloon-Based Wide Planar Ablation on Epicardial Adipose Tissue in Persistent Atrial Fibrillation. 基于热气球的宽平面消融对持续性心房颤动心外膜脂肪组织的慢性影响。

Circulation reports Pub Date : 2023-09-16 eCollection Date: 2023-10-10 DOI: 10.1253/circrep.CR-23-0073

Shiro Nakahara, Yuichi Hori, Reiko Fukuda, Hirotsugu Sato, Hideyuki Aoki, Tetsuya Ishikawa, Yuji Itabashi, Sayuki Kobayashi, Isao Taguchi, Yasuo Okumura

{"title":"Chronic Effect of HotBalloon-Based Wide Planar Ablation on Epicardial Adipose Tissue in Persistent Atrial Fibrillation.","authors":"Shiro Nakahara, Yuichi Hori, Reiko Fukuda, Hirotsugu Sato, Hideyuki Aoki, Tetsuya Ishikawa, Yuji Itabashi, Sayuki Kobayashi, Isao Taguchi, Yasuo Okumura","doi":"10.1253/circrep.CR-23-0073","DOIUrl":"10.1253/circrep.CR-23-0073","url":null,"abstract":"Background: Adverse atrial remodeling, including epicardial adipose tissue (EAT) deposition in the left atrium (LA), is implicated in atrial fibrillation (AF). Radiofrequency hotballoon (RHB) ablation can produce wide planar lesions because the balloon is highly compliant; however, chronic effects of RHB ablation on structural remodeling remain unknown. This clinical-experimental investigation characterized chronic effects of RHB ablation on EAT in persistent AF (PsAF). Methods and Results: The clinical study involved 91 patients (obese, n=30; non-obese, n=61) undergoing RHB ablation for PsAF. LA-EAT was assessed from computed tomography images obtained before ablation and 6 months later. Tissue effects of RHB ablation were explored in a chronic swine model. RHB ablation significantly reduced LA volume (mean [±SD] 177.7±29.7 vs. 138.4±29.6 mL; P<0.001) and LA-EAT volume (median [interquartile range] 22.0 [12.4-33.3] vs. 16.5 [7.9-25.8] mL; P<0.001). The reduction in EAT was significantly greater in the pulmonary vein (PV) antrum than in other LA regions (37.9% vs. 15.8%; P<0.001). The percentage reduction in PV antrum EAT was equivalent between obese and non-obese patients, as was the postablation success rate (73% vs. 70%; P=0.77). RHB ablation produced transmural lesions reaching the pigs' epicardial fat region. Conclusions: RHB-based planar-transmural lesions altered the structurally remodeled LA, including EAT. Further studies are needed to determine whether factors other than PV isolation contribute to the clinical success of RHB ablation.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"5 10","pages":"371-380"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7c/4d/circrep-5-371.PMC10561997.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Content 内容

Circulation reports Pub Date : 2023-09-08 DOI: 10.1253/circrep.cr-5-content9

引用次数: 0

Content 内容

Circulation reports Pub Date : 2023-08-10 DOI: 10.1253/circrep.cr-5-content8

引用次数: 0

Message From the Editor-in-Chief　― Circulation Reports: 4 Years of Progress After Launch ― 总编辑寄语-发行量报告:发行后四年的进展-

Circulation reports Pub Date : 2023-01-10 DOI: 10.1253/circrep.cr-66-0010

M. Sata

引用次数: 0

Validation of Japanese Bleeding Risk Criteria in Patients After Percutaneous Coronary Intervention and Comparison With Contemporary Bleeding Risk Criteria 经皮冠状动脉介入治疗后日本出血风险标准的验证及与当代出血风险标准的比较

Circulation reports Pub Date : 2022-04-16 DOI: 10.1253/circrep.CR-22-0023

Takeshi Shimizu, Yuya Sakuma, Yuta Kurosawa, Yuuki Muto, Akihiko Sato, S. Abe, T. Misaka, M. Oikawa, A. Yoshihisa, T. Yamaki, K. Nakazato, T. Ishida, Y. Takeishi

{"title":"Validation of Japanese Bleeding Risk Criteria in Patients After Percutaneous Coronary Intervention and Comparison With Contemporary Bleeding Risk Criteria","authors":"Takeshi Shimizu, Yuya Sakuma, Yuta Kurosawa, Yuuki Muto, Akihiko Sato, S. Abe, T. Misaka, M. Oikawa, A. Yoshihisa, T. Yamaki, K. Nakazato, T. Ishida, Y. Takeishi","doi":"10.1253/circrep.CR-22-0023","DOIUrl":"https://doi.org/10.1253/circrep.CR-22-0023","url":null,"abstract":"Background: The utility of the Japanese version of high bleeding risk (J-HBR) criteria compared with contemporary bleeding risk criteria, including Academic Research Consortium for High Bleeding Risk criteria, has not been fully investigated. Methods and Results: This study included patients who underwent percutaneous coronary intervention between 2010 and 2019. The J-HBR score was calculated by assigning 1 point for each major criterion and 0.5 points for each minor criterion in the J-HBR criteria. Among 1,643 patients, 1,143 (69.6%) met the J-HBR criteria. Accumulated major bleeding event rates at 1 year were higher among those who met the J-HBR criteria (4.8% vs. 0.6%; P<0.001). J-HBR criteria had higher sensitivity (94.8%) and lower specificity (31.4%) than contemporary bleeding risk criteria in predicting major bleeding. Bleeding events increased with increasing J-HBR score. The C statistic for the J-HBR score for predicting major bleeding at 1 year was 0.75 (95% confidence interval 0.69–0.81), and is comparable to that of other risk scores. In multivariate analysis, of the factors included in J-HBR criteria, chronic kidney disease, heart failure, and active malignancy were associated with major bleeding. Conclusions: J-HBR criteria identified patients at high bleeding risk with high sensitivity and low specificity. Bleeding risk was closely related to J-HBR score and its individual components. The discriminative ability of the J-HBR score was comparable to that of contemporary bleeding risk scores.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"18 1","pages":"230 - 238"},"PeriodicalIF":0.0,"publicationDate":"2022-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74690624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Impact of Prehospital 12-Lead Electrocardiography and Destination Hospital Notification on Mortality in Patients With Chest Pain　― A Systematic Review ― 院前12导联心电图和目的地医院通知对胸痛患者死亡率的影响——一项系统综述

Circulation reports Pub Date : 2022-04-15 DOI: 10.1253/circrep.cr-22-0003

T. Nakashima, Katsutaka Hashiba, M. Kikuchi, J. Yamaguchi, S. Kojima, H. Hanada, T. Mano, Takeshi Yamamoto, A. Tanaka, K. Matsuo, Naoki Nakayama, Osamu Nomura, T. Matoba, Y. Tahara, H. Nonogi

{"title":"Impact of Prehospital 12-Lead Electrocardiography and Destination Hospital Notification on Mortality in Patients With Chest Pain　― A Systematic Review ―","authors":"T. Nakashima, Katsutaka Hashiba, M. Kikuchi, J. Yamaguchi, S. Kojima, H. Hanada, T. Mano, Takeshi Yamamoto, A. Tanaka, K. Matsuo, Naoki Nakayama, Osamu Nomura, T. Matoba, Y. Tahara, H. Nonogi","doi":"10.1253/circrep.cr-22-0003","DOIUrl":"https://doi.org/10.1253/circrep.cr-22-0003","url":null,"abstract":"Background: To achieve early reperfusion therapy for ST-elevation myocardial infarction (STEMI), proper and prompt patient transportation and activation of the catheterization laboratory are required. We investigated the efficacy of prehospital 12-lead electrocardiogram (ECG) acquisition and destination hospital notification in patients with STEMI. Methods and Results: This is a systematic review of observational studies. We searched the PubMed database from inception to March 2020. Two reviewers independently performed literature selection. The critical outcome was short-term mortality. The important outcome was door-to-balloon (D2B) time. We used the GRADE approach to assess the certainty of the evidence. For the critical outcome, 14 studies with 29,365 patients were included in the meta-analysis. Short-term mortality was significantly lower in the group with prehospital 12-lead ECG acquisition and destination hospital notification than in the control group (odds ratio 0.72; 95% confidence interval [CI] 0.61–0.85; P<0.0001). For the important outcome, 10 studies with 2,947 patients were included in the meta-analysis. D2B time was significantly shorter in the group with prehospital 12-lead ECG acquisition and destination hospital notification than in the control group (mean difference −26.24; 95% CI −33.46, −19.02; P<0.0001). Conclusions: Prehospital 12-lead ECG acquisition and destination hospital notification is associated with lower short-term mortality and shorter D2B time than no ECG acquisition or no notification among patients with suspected STEMI outside of a hospital.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"103 1","pages":"187 - 193"},"PeriodicalIF":0.0,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82550836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Successful Catheter Ablation of Atrial Fibrillation in a Patient With an Abnormal Septum in the Left Atrium 左心房中隔异常患者心房颤动的导管消融成功

Circulation reports Pub Date : 2022-04-09 DOI: 10.1253/circrep.CR-22-0026

N. Kobayashi, Shunsuke Uetake, Nobuaki Itoh, Y. Miyauchi

引用次数: 0

Effects of Nitric Oxide Synthase 3 Gene Polymorphisms on Cardiovascular Events in a General Japanese Population　― The Yamagata (Takahata) Study ― 一氧化氮合酶3基因多态性对日本普通人群心血管事件的影响——山形(高畑)研究

Circulation reports Pub Date : 2022-04-06 DOI: 10.1253/circrep.cr-21-0159

Y. Saito, Y. Otaki, Tetsu Watanabe, M. Wanezaki, D. Kutsuzawa, S. Kato, H. Tamura, S. Nishiyama, T. Arimoto, Hiroki Takahashi, Y. Ueno, T. Konta, Masafumi Watanabe

{"title":"Effects of Nitric Oxide Synthase 3 Gene Polymorphisms on Cardiovascular Events in a General Japanese Population　― The Yamagata (Takahata) Study ―","authors":"Y. Saito, Y. Otaki, Tetsu Watanabe, M. Wanezaki, D. Kutsuzawa, S. Kato, H. Tamura, S. Nishiyama, T. Arimoto, Hiroki Takahashi, Y. Ueno, T. Konta, Masafumi Watanabe","doi":"10.1253/circrep.cr-21-0159","DOIUrl":"https://doi.org/10.1253/circrep.cr-21-0159","url":null,"abstract":"Background: Single nucleotide polymorphisms (SNPs) in nitric oxide synthase 3 (NOS3) are associated with cardiovascular risk factors. However, it is not clear whether the NOS3 SNP is a genetic risk factor for cardiovascular diseases. Methods and Results: This prospective cohort study included 2,726 subjects aged ≥40 years who participated in a community-based health checkup. We genotyped 639 SNPs, including 2 NOS3 SNPs (rs1799983 and rs1808593). All subjects were monitored prospectively over a median follow-up period of 16.0 years, with the endpoint being cardiovascular events, including cardiovascular death and/or non-fatal myocardial infarction. Kaplan-Meier analysis demonstrated that both rs1799983 GT/TT and rs1808593 GG carriers had a higher risk of the endpoint than non-carriers. Univariate and multivariate Cox proportional hazard regression analyses revealed that both rs1799983 GT/TT and rs1808593 GG were independently associated with cardiovascular events after adjusting for confounding risk factors. The net reclassification index and integrated discrimination index were significantly improved by the addition of NOS3 SNPs as cardiovascular risk factors. Conclusions:NOS3 gene polymorphisms could be genetic risk factors for cardiovascular events in the general Japanese population, and could be used to facilitate the early identification of individuals at high risk of cardiovascular events.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"17 1","pages":"222 - 229"},"PeriodicalIF":0.0,"publicationDate":"2022-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75035077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1