{"title":"反复心力衰竭住院治疗对心力衰竭患者日常生活活动能力下降的影响，并保留或轻度降低射血分数。","authors":"Yuta Ozaki, Yusuke Uemura, Shogo Yamaguchi, Takashi Okajima, Takayuki Mitsuda, Shinji Ishikawa, Kenji Takemoto, Toyoaki Murohara, Masato Watarai","doi":"10.1253/circrep.CR-25-0056","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>For patients with heart failure (HF) and preserved ejection fraction (HFpEF) or mildly reduced ejection fraction (HFmrEF), there is no treatment that improves survival, but some will reduce HF hospitalizations. Recurrent HF admissions may impair activities of daily living (ADL) and increase the societal burden.</p><p><strong>Methods and results: </strong>We analyzed 130 patients with HFpEF or HFmrEF who had recurrent HF hospitalizations. The multivariate linear mixed-effects model revealed that HF hospitalization frequency remained an independent predictor of ADL decline, as evaluated by the Barthel index.</p><p><strong>Conclusions: </strong>Recurrent hospitalization for HF contributes to ADL decline. Preventing rehospitalization due to HF is crucial.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"542-546"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240618/pdf/","citationCount":"0","resultStr":"{\"title\":\"Impact of Recurrent Heart Failure Hospitalization on Decline in Activities of Daily Living for Patients With Heart Failure and Preserved or Mildly Reduced Ejection Fraction.\",\"authors\":\"Yuta Ozaki, Yusuke Uemura, Shogo Yamaguchi, Takashi Okajima, Takayuki Mitsuda, Shinji Ishikawa, Kenji Takemoto, Toyoaki Murohara, Masato Watarai\",\"doi\":\"10.1253/circrep.CR-25-0056\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>For patients with heart failure (HF) and preserved ejection fraction (HFpEF) or mildly reduced ejection fraction (HFmrEF), there is no treatment that improves survival, but some will reduce HF hospitalizations. Recurrent HF admissions may impair activities of daily living (ADL) and increase the societal burden.</p><p><strong>Methods and results: </strong>We analyzed 130 patients with HFpEF or HFmrEF who had recurrent HF hospitalizations. The multivariate linear mixed-effects model revealed that HF hospitalization frequency remained an independent predictor of ADL decline, as evaluated by the Barthel index.</p><p><strong>Conclusions: </strong>Recurrent hospitalization for HF contributes to ADL decline. Preventing rehospitalization due to HF is crucial.</p>\",\"PeriodicalId\":94305,\"journal\":{\"name\":\"Circulation reports\",\"volume\":\"7 7\",\"pages\":\"542-546\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240618/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Circulation reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1253/circrep.CR-25-0056\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/10 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Circulation reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1253/circrep.CR-25-0056","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/10 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Impact of Recurrent Heart Failure Hospitalization on Decline in Activities of Daily Living for Patients With Heart Failure and Preserved or Mildly Reduced Ejection Fraction.
Background: For patients with heart failure (HF) and preserved ejection fraction (HFpEF) or mildly reduced ejection fraction (HFmrEF), there is no treatment that improves survival, but some will reduce HF hospitalizations. Recurrent HF admissions may impair activities of daily living (ADL) and increase the societal burden.
Methods and results: We analyzed 130 patients with HFpEF or HFmrEF who had recurrent HF hospitalizations. The multivariate linear mixed-effects model revealed that HF hospitalization frequency remained an independent predictor of ADL decline, as evaluated by the Barthel index.
Conclusions: Recurrent hospitalization for HF contributes to ADL decline. Preventing rehospitalization due to HF is crucial.
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