African health sciences最新文献

{"title":"Predictors of adherence to Hypertension Self-management practices among older persons attending a rural hospital in Uganda.","authors":"Anna Kabona Mbaseege, Jane Frances Namatovu, Innocent Besigye, Sarah Kiguli","doi":"10.4314/ahs.v25i2.13","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.13","url":null,"abstract":"<p><strong>Background: </strong>Hypertension self-management practices have proven beneficial in controlling blood pressure and preventing complications as part of the chronic care model. However, these practices among older persons 50 years and above have not been well evaluated in sub Saharan Africa despite the emerging hypertension burden in the region.</p><p><strong>Objective: </strong>The study determined adherence to hypertension self-management practices and factors associated with good adherence among older persons attending the Non-Communicable Diseases clinic in rural Eastern Uganda.</p><p><strong>Methods: </strong>In a facility-based cross-sectional study, individuals 50 years and above were selected consecutively from the bi-weekly hypertension out-patient clinic from January-February 2023. The adopted Hypertension Self-Care Activity Level Effects (H-SCALE) questionnaire was used to assess adherence to the self-management practices. The generalised linear model was used to determine predictors of adherence to the self-management practices.</p><p><strong>Results: </strong>Of the 74 hypertensive patients, level of adherence to the hypertension self-management practices of atleast 4 out of the 6 practices was 27 (36.5%). Adherence to diet, weight management, medication adherence, aerobic physical activity, non-smoking and recommended alcohol intake was 0(0%), 23(31.1%), 33(44.6%), 37(50.0%), 67 (90.5%) and 74(100%) respectively. Being married and having hypertension for less than 4 years were associated with good adherence p-value 0.01 and 0.03 respectively.</p><p><strong>Conclusions: </strong>Social factors like marriage and duration with hypertension were associated with better adherence to hypertension self-management practices. We recommend better implementation of the chronic care model to improve hypertension control in the community.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"94-100"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low prevalence but high resistance of Extended Spectrum Beta-lactamase producing <i>Klebsiella pneumoniae</i> isolated from Hospitals in the Ashanti Region of Ghana.","authors":"Elizabeth Akua Baidoo, Vivian Etsiapa Boamah, Hayford Odoi, Yaw Duah Boakye, Christian Agyare","doi":"10.4314/ahs.v25i2.4","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.4","url":null,"abstract":"<p><strong>Background: </strong>Antibiotic resistance continues to be a threat to public health worldwide, with its associated increased healthcare costs and loss of human lives. Despite the increasing reports of multi-drug resistant (MDR) <i>Klebsiella pneumoniae</i> (<i>K. pneumoniae</i>), its prevalence and resistance patterns remain under-reported in several developing countries, including Ghana.</p><p><strong>Objectives: </strong>This study hence sought to investigate the prevalence and resistance patterns of <i>K. pneumoniae</i> isolates from five selected hospitals in the Ashanti region of Ghana.</p><p><strong>Methods: </strong><i>K. pneumoniae</i> isolates were identified using biochemical tests, API 20 E and Matrix Assisted Laser Desorption Ionisation-Time of Flight Mass Spectrometry (MALDI-TOF MS). AST and ESBL production were determined phenotypically and via PCR.</p><p><strong>Results: </strong>Twenty (20) <i>K. pneumoniae</i> isolates were confirmed from the samples. The isolates were resistant to ampicillin (100%), ciprofloxacin (76.67%), co-trimoxazole (75%), chloramphenicol (63.33%) and cephalosporins (76.67 to 55%). Eighteen of the K. pneumoniae isolates (90%) were multi-drug resistant (MDR) while 60% of the isolates (n=12) produced Extended Spectrum Beta-Lactamases (ESBL) with blaCTX-M, blaSHV and blaTEM β-lactamase resistant encoding genes confirmed in 83, 75 and 33% of the isolates respectively.</p><p><strong>Conclusion: </strong>There is low prevalence but high multidrug resistance and high production of ESBL among <i>K. pneumoniae</i> isolates from the selected hospitals.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"20-29"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of multi-perspective nursing based on the whole-course ERAS concept during laparoscopic fundoplication in patients with PPI-dependent gastroesophageal reflux disease.","authors":"Lina Wang, Ting Zhou, Weiqiong Wang, Wenjie Cai","doi":"10.4314/ahs.v25i2.21","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.21","url":null,"abstract":"<p><strong>Background: </strong>To examine the impact of a multi-perspective nursing approach using the whole-course Enhanced Recovery After Surgery concept on laparoscopic fundoplicationoutcomes for patients with proton pump inhibitor-dependent gastroesophageal reflux disease.</p><p><strong>Methodology: </strong>This study was a randomized controlled trial. 98 proton pump inhibitor -dependent gastroesophageal reflux disease patients who underwent aparoscopic fundoplication in our hospital from Jan 2020 to Dec 2022 were randomly divided into two groups using a random number table. Group A (n=49) received multi-perspective nursing based on the gastroesophageal reflux disease concept in addition to routine nursing intervention, while Group B (n=49) received only routine aparoscopic fundoplication perioperative nursing intervention. The groups were compared in terms of first postoperative anal exhaust time, feeding time, time out of bed, hospital stay, Visual Analogue Scale scores before and after surgery, Hamilton Anxiety Scale and Hamilton Depression Scale scores, nursing satisfaction, and complications.</p><p><strong>Results: </strong>Group A showed significant improvements in various postoperative outcomes compared to Group B, including shorter anal exhaust time, feeding time, time out of bed, and hospital stay (P<0.05). Group A also had lower VAS pain scores, lower Hamilton Anxiety Scale and Hamilton Depression Scale scores, and higher nursing satisfaction scores than Group B (P<0.05).</p><p><strong>Conclusion: </strong>Multi-perspective nursing with Enhanced Recovery After Surgery can improve gastroesophageal reflux disease patients' recovery, pain relief, and nursing satisfaction post- aparoscopic fundoplication.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"161-167"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lesch-Nyhan syndrome a dental approach: case report.","authors":"Priscilla Sena Souza Luz Campos, Luís Cândido Pinto da Silva, Paulo Franco Taitson, Lara Alves da Silva Oliveira, Laura Camilo Bautista","doi":"10.4314/ahs.v25i2.37","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.37","url":null,"abstract":"<p><p>Lesch-Nyhan syndrome was first described in 1964. It is an X-linked recessive disorder caused by the absence of the enzyme hypoxanthine-guanine phosphoribosyl ransferase (HGPRT), which is involved in the metabolism of purines (nitrogenous bases that make up nucleotide). The absence of the enzyme leads to motor and neurological dysfunction, increased uric acid production, and mental retardation. One of the main characteristics of this syndrome is compulsive self-mutilation, such as biting the lips, tongue, and fingers. Men are the most affected and the prevalence is 1/380,000 live births. Several types of treatments are managed to reduce the manifestations of Lesch-Nyhan Syndrome, such as the placement of oral appliances, dental extractions, and drug therapy, the main one being Allopurinol, which can reduce the concentration of uric acid in the body. The role of the dentist becomes essential since teeth represent the main instrument for self-mutilation. In this sense, the article aims to describe the Lesch-Nyhan syndrome, the possible treatments and report a clinical case of a 4-year-old male patient who presented the syndrome.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"314-319"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy comparison of CO2 laser treatment and LEEP surgery for cervical intraepithelial neoplasia with high-risk HPV infection.","authors":"Shanshan Huang, Hongling Guo, Tingting Yu, Guojian Gu, Xiaofa Wu, Xiang Li, Yan Cheng","doi":"10.4314/ahs.v25i2.8","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.8","url":null,"abstract":"<p><strong>Background: </strong>To investigate the clinical efficacy of CO2 laser and loop electrosurgical excision procedure (LEEP) in the treatment of cervical intraepithelial neoplasia (CIN) with high-risk human papillomavirus (HPV) infection.</p><p><strong>Methods: </strong>A total of 150 CIN patients with high-risk HPV infection admitted to our hospital from December 2020 to June 2022 were divided into CO2 laser treatment group (CO2 group) with 63 cases and LEEP treatment group (LEEP group) with 87 cases based on treatment principles and patient preferences. The postoperative recovery time, CIN treatment effect, high-risk HPV clearance rate, treatment safety, and recurrence rate were compared between the two groups.</p><p><strong>Results: </strong>The vaginal discharge time, vaginal bleeding time, and wound healing time in the CO2 group were significantly lower than those in the LEEP group (P < 0.05). The incidence of adverse events in the CO2 group was 14.29%, which was significantly lower than that in the LEEP group (28.74%, P < 0.05).</p><p><strong>Conclusion: </strong>CO2 laser and LEEP surgery for the treatment of CIN combined with high-risk HPV infection both have good clinical efficacy, and CO2 laser can effectively shorten the postoperative recovery time with good safety.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"52-58"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometrial cancer and associated risk factors among non-pregnant women with abnormal uterine bleeding in Kampala, Uganda: a 7-year experience from a Single Institution.","authors":"Betty A Kassimo, James J Yahaya, Emmanuel Othieno, Livex A Okwi, Michael Odida","doi":"10.4314/ahs.v25i2.18","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.18","url":null,"abstract":"<p><strong>Introduction: </strong>Endometrial cancer is the most common malignancy of among postmenopausal women in high income countries, however, its prevalence has been reported to be raising even in low-and middle-income countries due to change in lifestyle behaviors. We aimed to determine the prevalence of endometrial cancer and its associated factors among non-pregnant women with abnormal uterine bleeding.</p><p><strong>Methods: </strong>After obtaining ethical approval from the Research Ethical Committee of the Makerere college of Health Sciences, we retrospectively retrieved and analyzed the paraffin embedded tissue blocks of 159 patients who were non-pregnant women and they were presenting with abnormal uterine bleeding from January 2012 to December 2018. The clinical and pathological information was obtained from the patient's files. Statistical analysis was done using SPSS version 23.0. Binary logistic regression analysis was applied in determining the risk factors of endometrial cancer. A two-tailed p -value <0.05 was considered significant.</p><p><strong>Results: </strong>The overall mean age of the patients was 36.4 ± 13.7 years and the vast majority 71.1% (113/159) of the patients were premenopausal women. The prevalence of endometrial cancer was 11.9% (19/159). Being postmenopausal (AOR = 7.7, 95% CI = 2.155 - 27.666, p = 0.003), having menarche below 12 years (AOR = 4.5, 95% CI = 0.217-0.390, p<0.001), being obese (AOR = 2.5, 95% CI = 0.305-0.822, p = 0.01), and being nulliparous (AOR = 5.4, 95% CI = 0.292-0.957, p = 0.009) were significantly associated with endometrial cancer. However, use of contraceptive pills, family history of reproductive cancers, having hypertension and/or diabetes mellitus all were not associated with endometrial cancer.</p><p><strong>Conclusion: </strong>Our study has further proven that, there is a significant proportion of non-pregnant women with AUB who have endometrial cancer. Using the clinical parameters such as age of the patient and age at menarche, nulliparity and obesity, it may help in increasing the index of clinical suspicion in daily clinical practice to diagnosing endometrial cancer among women with AUB at early stage. This will help in improving the prognosis of the patients.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"131-140"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between hand injuries due to occupational accidents and Vitamin D deficiency.","authors":"Ali Sağlık, Tufan Akın Giray, Tarık Ocak","doi":"10.4314/ahs.v25i2.24","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.24","url":null,"abstract":"<p><strong>Background: </strong>Bone fractures due to occupational accidents cause labor and cost losses in the world. Vitamin D deficiency is common in the world including industrialized countries. This study aimed to investigate the relationship between fracture and vitamin D levels in patients with wrist fractures due to occupational accidents.</p><p><strong>Methods: </strong>This study was conducted in a study group consisting of patients who were admitted to the emergency department of a university hospital due to occupational accidents and were thought to have a fracture of the hand or wrist. Blood samples were analyzed biochemically and vitamin D levels were obtained.</p><p><strong>Results: </strong>Vitamin D3 level was 16.3 ng/mL in patients with fractures and 21 ng/mL in patients without fractures, which was statistically significant (p<0.05). Vitamin D deficiency was found in %60.2 of patients with fractures, while vitamin D deficiency was found in %50.2 of patients with fractures and there was no statistical difference (p>0.112). Vitamin D deficiency was found in %39.8 of patients with hand injury without fracture, whereas vitamin D deficiency was not detected in %33 of patients with hand injury and the comparison was statistically significant (p<0.05).</p><p><strong>Conclusion: </strong>There is insufficient data in the literature on the relationship between bone fractures and vitamin D levels and the vitamin D levels required to prevent bone fractures. In this study, a statistically significant difference was found between the vitamin D levels of patients with fractures and those of patients without fractures. This study is beneficial for the literature in this respect, but extensive studies on the relationship between vitamin D and fractures are needed.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"186-194"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Willingness of secondary school adolescents to get vaccinated against Malaria: a cross-sectional study in Enugu, South-East Nigeria.","authors":"Obinna C Nduagubam, Edmund N Ossai, Awoere T Chinawa, Vivian O Onukwuli, Ndubuisi A Uwaezuoke, Chinyere N Okafor, Josephat M Chinawa","doi":"10.4314/ahs.v25i2.9","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.9","url":null,"abstract":"<p><strong>Background: </strong>Malaria is a serious public health challenge both in children and adolescents.</p><p><strong>Objectives: </strong>This study was aimed to document the willingness of the adolescents to accept vaccine and its associated factors.</p><p><strong>Methodology: </strong>This was an observational and cross-sectional study on four hundred and ninety-six secondary school adolescents in six secondary schools in Enugu from June 2023 to September 2023. Data entry and analysis were done using IBM Statistical Package for Social Sciences (SPSS) statistical software version 25.</p><p><strong>Results: </strong>A reasonable proportion of the respondents, 68.1% were willing to receive malaria vaccine. A higher proportion of the respondents, 59.3% knew that malaria vaccination could protect against seasonal influenza. Less than one third of the respondents, 32.1% had good knowledge of malaria vaccination. The respondents who were less than 15 years were twice more likely to receive malaria vaccination when compared with those who were 15 years and above, (AOR=2.2, 95%CI: 1.1-4.7). The respondents who were males were about twice less likely to receive malaria vaccination when compared with those who were females, (AOR=0.6, 95%CI: 0.4-0.9). The respondents who had good knowledge of malaria vaccination were twice more likely to receive malaria vaccination when compared with those who had poor knowledge, (AOR=2,2, 95%CI: 1.4-3.4).</p><p><strong>Conclusion: </strong>A reasonable proportion of secondary school adolescents were willing to receive the malaria vaccine. Willingness to receive malaria vaccine is influenced by gender, knowledge of malaria vaccine and age of the adolescent.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"59-69"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical comparison of simultaneous integrated and sequential boost IMRT of tumor bed after breast conserving surgery.","authors":"Minghai Shao, Caiping Jiang, Yunxiang Yao, Weifang Yang, Haijian Jia, Yichao Shen, Yanli Wang, Bin Yu","doi":"10.4314/ahs.v25i2.20","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.20","url":null,"abstract":"<p><strong>Background: </strong>To explore the clinical effect compare between the simultaneous-integrated boost and sequential-boost intensity modulated radiotherapy in early breast cancer patients after breast conserving surgery.</p><p><strong>Methodology: </strong>According to the different postoperative radiotherapy methods, 66 early breast cancer patients after breast-conserving surgery were divided into two groups, 34 in the simultaneous-integrated boost group and 32 in the sequential-boost intensity group. Adverse reactions, cosmetic effects, local recurrence rate, progression-free survival and overall survival rates were compared.</p><p><strong>Results: </strong>No statistical significance in the incidence of acute skin reaction, advanced skin reaction, myelosuppression, radiation pneumonia and other adverse reactions between two groups were observed. The fine rate of simultaneous-integrated boost group was slightly better than the sequential-boost intensity group. And the follow-up rate of the two groups was 100%. The progression-free survival rate of the simultaneous-integrated boost group and the sequential-boost intensity group were 100% and 96.88%, respectively; The overall survival rates of the two groups were all 100%; One patient in the sequential-boost intensity group had recurrence (3.13%), while none in the simultaneous-integrated boost group. No significant difference in local recurrence rate, progression-free survival and overall survival rates in the two groups were found.</p><p><strong>Conclusion: </strong>Simultaneous-integrated boost ensures breast appearance and survival without added radiotherapy side effects vs sequential-boost intensity.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"153-160"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of human onchocerciasis in Ethiopia: a systematic review and meta-analysis.","authors":"Tadesse Hailu, Getaneh Alemu, Megbaru Alemu","doi":"10.4314/ahs.v25i2.3","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.3","url":null,"abstract":"<p><strong>Background: </strong>Onchocerciasis is a vector-borne disease caused by the tissue nematode Onchocerca volvulus. Despite its importance for targeted intervention, the national prevalence is not well addressed in Ethiopia.</p><p><strong>Objective: </strong>This review aimed to determine the pooled prevalence of human onchocerciasis in Ethiopia.</p><p><strong>Methods: </strong>All literature published from 1973 to July 2022 were included in the present review A systematic review and meta-analysis was done following PRISMA guideline and checklists. Studies conducted on the prevalence of onchocerciasis in Ethiopia were searched from PubMed, Google Scholar, Scopus, ScienceDirect, and MEDLINE databases. Comprehensive meta-analysis version 2.2 software was used to calculate the pooled prevalence. Heterogeneity between studies was assessed using Cochrane Q test and I2 test statistics based on the random effects model.</p><p><strong>Results: </strong>Twenty-one studies, which recruited a total of 14,983 participants, were included in the present review. The overall pooled prevalence of Onchocerca volvulus in Ethiopia was 31.8% using the random effect model. The heterogeneity between studies was high and significant (Q = 2881.2, I2 = 99.3%, P-value < 0.001).</p><p><strong>Conclusions: </strong>The prevalence of onchocerciasis is high in Ethiopia, despite the implementation of prevention and control measures. Therefore, the existing mass drug administration program should be strengthened.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"10-19"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}