African health sciences最新文献

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Sleep quality and its relationship with physical activity and frailty syndrome among hospitalized older adults in North Iran. 伊朗北部住院老年人睡眠质量及其与身体活动和虚弱综合征的关系
IF 0.9
African health sciences Pub Date : 2026-03-01 DOI: 10.4314/ahs.v26i1.11
Leila Zahed Nakhjiri, Azar Darvishpour, Ali Nouri, Ameneh Beig Mohammadi
{"title":"Sleep quality and its relationship with physical activity and frailty syndrome among hospitalized older adults in North Iran.","authors":"Leila Zahed Nakhjiri, Azar Darvishpour, Ali Nouri, Ameneh Beig Mohammadi","doi":"10.4314/ahs.v26i1.11","DOIUrl":"https://doi.org/10.4314/ahs.v26i1.11","url":null,"abstract":"<p><strong>Background: </strong>Sleep disorders are a prevalent concern among older adults, contributing to reduced physical function. A bidirectional relationship between sleep disorders and frailty syndrome has been suggested.</p><p><strong>Objectives: </strong>This study aimed to investigate sleep quality and its associations with physical activity and frailty syndrome among hospitalized older adults.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in 2022 among 150 hospitalized older adults in East Guilan, northern Iran, using convenience sampling. PSQI, CHAMPS, and TFI questionnaires were employed as research instruments. Data were analyzed using SPSS version 16, applying descriptive statistics and Spearman correlation coefficients.</p><p><strong>Results: </strong>The majority (76%) of participants had poor sleep quality, and 58.66% reported being physically active. Additionally, 58% were non-frail. Although no significant relationship was found between the total sleep quality score and frailty syndrome, a significant correlation was observed between habitual sleep efficiency and all dimensions of frailty (physical, psychological, and social). A positive relationship was also found between sleep quality and physical activity (r = 0.20, p = 0.014).</p><p><strong>Conclusion: </strong>Improved physical activity was associated with better sleep quality, which may reduce risk of frailty. Promoting physical activity and improving sleep hygiene in hospitalized older adults could enhance health outcomes and reduce frailty risk.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"26 1","pages":"92-103"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlates of alcohol use among internally displaced adults in Northern Cross River, Nigeria: a cross-sectional study. 尼日利亚北克罗斯河境内流离失所成年人酒精使用的相关因素:一项横断面研究。
IF 0.9
African health sciences Pub Date : 2026-03-01 DOI: 10.4314/ahs.v26i1.9
Ugbe Maurice-Joel Ugbe, Peter Bassey Enyievi, Ekpereonne Babatunde Esu, Bernadine Nsa Ekpenyong, Aniekanabasi Jonathan Okon, Emmanuel Onen Ebri
{"title":"Correlates of alcohol use among internally displaced adults in Northern Cross River, Nigeria: a cross-sectional study.","authors":"Ugbe Maurice-Joel Ugbe, Peter Bassey Enyievi, Ekpereonne Babatunde Esu, Bernadine Nsa Ekpenyong, Aniekanabasi Jonathan Okon, Emmanuel Onen Ebri","doi":"10.4314/ahs.v26i1.9","DOIUrl":"https://doi.org/10.4314/ahs.v26i1.9","url":null,"abstract":"<p><strong>Background: </strong>Forced displacement is high globally as populations are increasingly displaced by conflicts and disasters. Substance misuse is increasingly recognized as a major cause of morbidity and mortality in displaced populations.</p><p><strong>Objectives: </strong>This study aimed to investigate the correlates of alcohol misuse among internally displaced adults in Northern Cross River, Nigeria.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in Ogoja displacement settlements. Three-hundred and thirty-five displaced adults were selected using snowball sampling method. Alcohol dependence was measured using the interviewer-administered Alcohol Use Disorder Identification Test (AUDIT) questionnaire. Data were analyzed using descriptive statistics, Chi-square, and multivariable logistic regression.</p><p><strong>Results: </strong>The prevalence of alcohol misuse was 26.3%. The multivariate analysis revealed that male gender (AOR=7.28; p<0.001), farming occupation (AOR=4.44; p=0.003), discrimination (AOR=3.49; p=0.001), financial strains (AOR=0.12; p=0.002), overcrowded shelters (AOR=3.49; p=0.001), fear of reprisals (AOR=2.49; p=0.016), and concerns about health and safety (AOR=0.087; p<0.001) were significantly associated with alcohol dependence among IDPs in this study.</p><p><strong>Conclusion: </strong>These findings indicate that nearly three out of every ten displaced adults were alcohol-dependent as a result of traumatic events, life events, and deprivation of basic care. Protection, social, and psychological remedies are required to foster relief and reintegration efforts for internally displaced persons in Nigeria.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"26 1","pages":"73-81"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthcare access difficulty due to fear of COVID-19 infection among women of reproductive age: multilevel mixed-effects logistic regression analysis. 育龄妇女因害怕COVID-19感染而难以获得医疗服务:多水平混合效应logistic回归分析
IF 0.9
African health sciences Pub Date : 2026-03-01 DOI: 10.4314/ahs.v26i1.3
Charles Natuhamya
{"title":"Healthcare access difficulty due to fear of COVID-19 infection among women of reproductive age: multilevel mixed-effects logistic regression analysis.","authors":"Charles Natuhamya","doi":"10.4314/ahs.v26i1.3","DOIUrl":"https://doi.org/10.4314/ahs.v26i1.3","url":null,"abstract":"<p><strong>Introduction: </strong>The coronavirus disease of 2019 (COVID-19) pandemic left lasting effects in all sectors globally. Particularly among women of reproductive age, it has instilled difficulty of accessing healthcare, which has been linked to fear of being exposed to the virus at health facilities. However, most studies especially in East Africa have narrowed COVID-19 related research to qualitative reviews and descriptive analyses due to inadequacy of COVID-19 data. The purpose of this study was to determine the relationship between health facility visiting and healthcare access difficulty due to fear of COVID-19 at health facilities, while exploring both individual and contextual determinants.</p><p><strong>Methods: </strong>The current study applied a multilevel logistic mixed-effects regression model to account for both individual and contextual dimensions in the study.</p><p><strong>Results: </strong>Overall, 30.0% of the women reported difficulty in accessing healthcare. Women who had visited a health facility in the past 4 weeks of the survey and had health insurance were associated with less healthcare access difficulty; (AOR= 0.73; 95% CI, 0.57-0.95) and (AOR= 0.74; 95% CI, 0.59-0.94) respectively. On the contrary, women who watched television, in households that had partially and completely lost household income due to the virus were associated with more difficulty; (AOR= 1.38; 95% CI, 1.10-1.74), (AOR= 2.09, 95% CI, 1.51-2.88) and (AOR= 2.40, 95% CI, 1.65-3.47) respectively. About 72% of the total variance in healthcare access difficulty was attributable to differences in enumeration areas (ICC= 0.72; 95% CI, 0.66-0.76), with less significant individual level contribution.</p><p><strong>Conclusion: </strong>Interventions that influence routine health facility visits can boost healthcare access among women. Enumeration area-specific interventions may be more effective.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"26 1","pages":"16-24"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medication errors among elderly in-patients at an urban national referral hospital in Tanzania: Prevalence and patient profiles in a low-resource setting. 坦桑尼亚一家城市国家转诊医院老年住院患者的用药错误:低资源环境下的患病率和患者概况
IF 0.9
African health sciences Pub Date : 2026-03-01 DOI: 10.4314/ahs.v26i1.16
Anita Kaligirwa, Emanuel L Peter, Paul E Alele
{"title":"Medication errors among elderly in-patients at an urban national referral hospital in Tanzania: Prevalence and patient profiles in a low-resource setting.","authors":"Anita Kaligirwa, Emanuel L Peter, Paul E Alele","doi":"10.4314/ahs.v26i1.16","DOIUrl":"https://doi.org/10.4314/ahs.v26i1.16","url":null,"abstract":"<p><strong>Background: </strong>Prescribing processes for the elderly are complex and challenging due to advanced age-related physiologic changes, co-morbidities, and co-medications which increase the chances of medication errors. There are, however, limited studies on the magnitude and profiles of medication errors among elderly populations in low-resource settings such as Tanzania.</p><p><strong>Objective: </strong>To determine the prevalence and profiles of medication errors among elderly in-patients at Mwananyamala Regional Referral Hospital (MRRH) in Dar-es-Salaam in Tanzania.</p><p><strong>Method: </strong>Medical data were analyzed of patients aged 65 years and above who were admitted to MRRH between March 2019 and February 2020 for any type of illness. Medication errors were systematically assessed using STOPP/START criteria.</p><p><strong>Results: </strong>Of 298 patients' records analyzed, the majority were females (n=151, 50.7%). Each patient had at least 2 diseases with an average of 5 types of medicines per patient. Twenty-eight patients (9.40%) had at least one error while the majority (n=270, 90.60%) had no medication errors. Medication omission accounted for the majority of errors present (86, 28.86%).</p><p><strong>Conclusion: </strong>Medication errors were prevalent among elderly patients admitted at MRRH, with diverse profiles related to the errors. Further studies are warranted to devise and adopt strategies to mitigate medication errors in this population.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"26 1","pages":"151-163"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the effect of preoperative multimedia video information on preoperative anxiety in patients undergoing procedures under central neuraxial block: a prospective, single-blind, randomized controlled study. 术前多媒体视频信息对中枢神经轴阻滞手术患者术前焦虑影响的比较:一项前瞻性、单盲、随机对照研究。
IF 0.9
African health sciences Pub Date : 2026-03-01 DOI: 10.4314/ahs.v26i1.8
K Duraiyarasan, Ruchi Kumari, Anshul Goyal, Munisha Agarwal, Neelam Prasad
{"title":"Comparison of the effect of preoperative multimedia video information on preoperative anxiety in patients undergoing procedures under central neuraxial block: a prospective, single-blind, randomized controlled study.","authors":"K Duraiyarasan, Ruchi Kumari, Anshul Goyal, Munisha Agarwal, Neelam Prasad","doi":"10.4314/ahs.v26i1.8","DOIUrl":"https://doi.org/10.4314/ahs.v26i1.8","url":null,"abstract":"<p><strong>Background and aims: </strong>Preoperative anxiety is one of the most common perioperative complications observed in patients undergoing surgery. The use of State Trait Anxiety Inventory (STAI) and Visual Analogue Scale (VAS-A) scores for anxiety has been demonstrated to reduce the preoperative anxiety levels. We evaluated the effect of preoperative multimedia video information on preoperative anxiety and haemodynamic parameters in patients undergoing procedures under central neuraxial block (CNB).</p><p><strong>Materials and methods: </strong>Sixty patients of either sex, aged 18-60 years undergoing elective surgeries under CNB were randomized into Group V (video) and Group NV (non-video). The primary outcomes included STAI score and VAS-A score assessed one hour prior to surgery. The secondary outcomes involved haemodynamic parameters before performing CNB and, patient's cooperation for CNB assessed by three-point scoring system.</p><p><strong>Results: </strong>Demographic parameters were comparable in both groups. The HR, SBP, DBP and MAP showed a significant increase from their baseline values before surgery in Group NV as compared to Group V (p<0.001). In Group V, STAI scores decreased significantly (p<0.001), while Group NV showed a significant increase (p<0.001). VAS-A scores for anxiety decreased in Group V and increased in Group NV before surgery (p<0.001). Group V demonstrated higher cooperation scores (score ≥2).</p><p><strong>Conclusion: </strong>Preoperative multimedia information was associated with reduced anxiety, better haemodynamic stability, and improved patient cooperation. Employing multimedia information in the form of video may prove beneficial for allaying preoperative anxiety in adults undergoing surgery under CNB.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"26 1","pages":"66-72"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges faced by medical officers in managing snakebite envenoming in North Karnataka, India: A qualitative thematic analysis. 印度北卡纳塔克邦医务人员在处理蛇咬伤事件时面临的挑战:定性专题分析。
IF 0.9
African health sciences Pub Date : 2026-03-01 DOI: 10.4314/ahs.v26i1.5
J Dodda Basava, N Chandan, Veerappa A Kothiwale, Phaniraj Vastrad, Kalesh M Karun, Manish J Barvaliya
{"title":"Challenges faced by medical officers in managing snakebite envenoming in North Karnataka, India: A qualitative thematic analysis.","authors":"J Dodda Basava, N Chandan, Veerappa A Kothiwale, Phaniraj Vastrad, Kalesh M Karun, Manish J Barvaliya","doi":"10.4314/ahs.v26i1.5","DOIUrl":"https://doi.org/10.4314/ahs.v26i1.5","url":null,"abstract":"<p><strong>Background: </strong>Snakebite envenoming is a neglected tropical disease and a major medical emergency in rural India. Medical officers play a key role in its management but often face systemic and operational barriers.</p><p><strong>Objective: </strong>To explore the challenges and barriers faced by medical officers in managing snakebite envenoming in rural Karnataka.</p><p><strong>Methods: </strong>A qualitative study using purposive sampling was conducted in selected Government healthcare centers (PHCs (Primary healthcare centre), CHCs (Community health centre), and THs (Taluk hospital) across Belagavi and Raichur districts of Karnataka. The interviews were transcribed verbatim and analyzed using reflexive thematic analysis. Ethical clearance was obtained from the institutional ethics committees.</p><p><strong>Results: </strong>Forty-eight medical officers (38 males and 10 females) participated in open-ended, face-to-face interviews conducted in English and 41.66% had 1-5 years of experience. Major barriers included delayed patient presentation due to reliance on traditional healers, poor awareness, shortages of antivenom (ASV), equipment, ICU facilities, inadequate training, staffing shortages, and persistent cultural misconceptions about snakebite.</p><p><strong>Conclusion: </strong>Strengthening infrastructure, ensuring ASV availability, enhancing training, and community education are crucial to improve outcomes and reduce mortality from snakebite envenoming in rural India.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"26 1","pages":"34-43"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of dementia among older persons in Northern Uganda, a cross-sectional study. 乌干达北部老年人痴呆患病率的横断面研究。
IF 0.9
African health sciences Pub Date : 2026-03-01 DOI: 10.4314/ahs.v26i1.10
Dan Langoya Oriba, Matovu Stephen Mwonge, Robert Mukisa, Martin N Kaddu-Mukasa, Felix Bongomin, Abdu K Musubire, Mark Kaddumukasa
{"title":"Prevalence of dementia among older persons in Northern Uganda, a cross-sectional study.","authors":"Dan Langoya Oriba, Matovu Stephen Mwonge, Robert Mukisa, Martin N Kaddu-Mukasa, Felix Bongomin, Abdu K Musubire, Mark Kaddumukasa","doi":"10.4314/ahs.v26i1.10","DOIUrl":"https://doi.org/10.4314/ahs.v26i1.10","url":null,"abstract":"<p><strong>Background: </strong>The burden and clinical correlates of dementia are unknown in Uganda. We therefore determined the prevalence and factors associated with dementia among older persons in Northern Uganda.</p><p><strong>Methods: </strong>In a cross-sectional study, adults aged 60 years and above attending the medical outpatient clinic at a tertiary Hospital from March 2022 to April 2022 were enrolled. The prevalence of dementia was determined using the Intervention for Dementia in Elderly Africans (IDEA) and the Instrumental Activities of Daily Living (IADL) tool henceforth presented as IDEA-IADL. Factors of association were collected using a standardized questionnaire.</p><p><strong>Results: </strong>A total of 271 eligible participants were enrolled into the study. Majority were age 60-69 years (153/271) and of male gender (165/271). The prevalence of dementia was 17.7% (48/271), severe dementia 7.4%, (20/271), moderate dementia 10.3%, (28/271). Factors independently associated with dementia were: participants aged between 80-89 years; (adjusted odds ratio (aOR): 9.7; 95% Confidence Interval (CI): 4.08-23.07, p< 0.001), family history of dementia (aOR: 3.4, 95CI: 1.62-7.04, p=0.001). history of depression (aOR: 2.7, 95CI: 1.40-5.02, p=0.003). Physical activity and cognitive exercise were associated protective factors with (aOR 0.1, 95CI: 0.03-0.24, p< 0.001) and (aOR 0.2, 95CI: 0.06-0.53, p<0.002) respectively.</p><p><strong>Conclusion: </strong>There burden of dementia among older persons in Northern Uganda is significant. Enhanced screening and early identification of dementia is recommended in this setting.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"26 1","pages":"82-91"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing tuberculosis treatment success: gender dynamics and designated drug supervisors in Tasikmalaya, Indonesia. 提高结核病治疗的成功率:印度尼西亚Tasikmalaya的性别动态和指定药品监督员。
IF 0.9
African health sciences Pub Date : 2026-03-01 DOI: 10.4314/ahs.v26i1.4
Endang Puji Astuti, Mutiara Widawati, Tri Wahono, Yuneu Yuliasih, Wawan Ridwan, Lukman Hakim, Mara Ipa
{"title":"Enhancing tuberculosis treatment success: gender dynamics and designated drug supervisors in Tasikmalaya, Indonesia.","authors":"Endang Puji Astuti, Mutiara Widawati, Tri Wahono, Yuneu Yuliasih, Wawan Ridwan, Lukman Hakim, Mara Ipa","doi":"10.4314/ahs.v26i1.4","DOIUrl":"https://doi.org/10.4314/ahs.v26i1.4","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis control in Tasikmalaya relies on competent drug supervisors (DS) to ensure adherence, yet knowledge gaps remain.</p><p><strong>Objectives: </strong>To assess factors influencing DS effectiveness in Tasikmalaya, Indonesia.</p><p><strong>Methods: </strong>A cross-sectional study of 121 DS was conducted. Data on sociodemographic factors, knowledge, attitudes, and practices were collected through validated questionnaires. Logistic regression was used to identify determinants of DS performance.</p><p><strong>Results: </strong>Female and officially designated DS were significantly more effective in ensuring adherence compared to males and voluntary DS. Overall knowledge was inadequate among most DS (95.9%). Cadres performed better than family members in supervisory tasks.</p><p><strong>Conclusion: </strong>Improving DS capacity-especially family and male supervisors-through structured training and official designation can enhance TB treatment outcomes.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"26 1","pages":"25-33"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of proton pump inhibitors and increased risk of fracture in type 2 DM and menopausal women: a systematic review and meta-analysis. 2型糖尿病和绝经期妇女使用质子泵抑制剂与骨折风险增加:一项系统回顾和荟萃分析
IF 0.9
African health sciences Pub Date : 2026-03-01 DOI: 10.4314/ahs.v26i1.15
Pradeep Battula, Poli Bhuvana Sree, Yapareddygari Sandhya Latha, Kotha Naga Poojitha, Kamini Venkata Subba Reddy, Setlem Sai Venkata Krishna, P Raghu Sri Charan, Krishna Undela
{"title":"Use of proton pump inhibitors and increased risk of fracture in type 2 DM and menopausal women: a systematic review and meta-analysis.","authors":"Pradeep Battula, Poli Bhuvana Sree, Yapareddygari Sandhya Latha, Kotha Naga Poojitha, Kamini Venkata Subba Reddy, Setlem Sai Venkata Krishna, P Raghu Sri Charan, Krishna Undela","doi":"10.4314/ahs.v26i1.15","DOIUrl":"https://doi.org/10.4314/ahs.v26i1.15","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the relationship between type 2 diabetes mellitus and postmenopausal women with fracture risk when using PPIs.</p><p><strong>Methods: </strong>We conducted an observational study to investigate the association between PPI use and an increased fracture risk in postmenopausal women and type 2 diabetes mellitus. We searched for epidemiological studies published between 2006 and 2023 in PubMed, Google Scholar, and other bibliographies of the retrieved papers. The pooled OR was obtained using the random-effects model, and a subgroup analysis was conducted.</p><p><strong>Results: </strong>Eight studies, including six cohorts and two case-control studies, were conducted with 1.3 million participants. In these studies, 1,63,346 cases of fracture risk were identified. The pooled effect estimate of these studies was OR 1.61, with a 95% CI of 1.36-1.90. This indicates a significant correlation between Type 2 diabetes mellitus, post-menopausal women, and the risk of fractures. The OR for type 2 DM alone was 1.34 (95% CI 1.14-1.57), and for menopausal women alone, the OR was 2.15 (95% CI 1.36-1.90). Notably, there was no evidence of publication bias.</p><p><strong>Conclusion: </strong>This meta-analysis provides strong evidence that PPI use in type 2 DM and menopausal women is significantly associated with the risk of developing fractures.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"26 1","pages":"134-150"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hand-washing practices at critical times in relation to childhood illnesses and under-nutrition among caregivers in Rongai sub-county, Kenya. 肯尼亚荣盖县护理人员在关键时刻与儿童疾病和营养不良有关的洗手做法。
IF 0.9
African health sciences Pub Date : 2026-03-01 DOI: 10.4314/ahs.v26i1.7
Sharon Chepng'eno Kemboi, Dorothy Mituki Mungiria, Rose Chepchirchir Ramkat, Maureen Jepkorir Cheserek
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