African health sciences最新文献

{"title":"The impact of femtosecond laser small incision lenticule extraction on accommodative function.","authors":"Liwen Li, Lu Liu, Wenjun Gou","doi":"10.4314/ahs.v25i2.42","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.42","url":null,"abstract":"<p><p>This retrospective case study assessed the influence of femtosecond laser small incision lenticule extraction (SMILE) on accommodative function. The study included 42 patients from August 2020 to July 2021 at Suining Central Hospital. They were categorized into near-vision fatigue (20 cases) and asymptomatic groups (22 cases) post-surgery. The near-vision fatigue group received visual training. Comparing pre-surgery, one week, and one month after surgery, accommodative changes were analyzed using variance and t-tests. The near-vision fatigue group had lower preoperative accommodative function (PAPM=0.16, PAF<0.001, PPRA=0.009). One-week post-surgery, they experienced further declines (PAPM=0.021, PAF=0.038, PPRA=0.001), but after one month of training, improvements were evident (PAPM<0.001, PBAF=0.005, PPRA<0.001). The asymptomatic group also had temporary declines one week after surgery, recovering by one month. Negative relative accommodation and accommodative response were minimally affected. SMILE surgery briefly reduced accommodative parameters, predominantly in the near-vision fatigue group. Appropriate training effectively alleviated postoperative near-vision discomfort. In conclusion, SMILE surgery affects accommodative function, leading to temporary declines in specific parameters. Adequate training mitigates these effects, enhancing postoperative comfort.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"360-367"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and factors associated with Hepatitis B infection in the general population: a cross-sectional study in Moshi municipality, North-Eastern Tanzania.","authors":"Elichilia R Shao, Innocent B Mboya, Jeremia J Pyuza, Florida Muro, Daniel Gunda, Harold L Mashauri, Semvua Kilonzo, Christian Issangya, Deborah Mchaile, Benjamin Shayo, Ephata Kaaya, Venance P Maro, Sarah Urasa, Gileard Masenga","doi":"10.4314/ahs.v25i2.5","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.5","url":null,"abstract":"<p><strong>Background: </strong>Hepatitis B virus (HBV) infection is a significant public health problem, even with the presence of affordable and effective vaccination. Toward hepatitis B elimination by 2030, it is essential to know the prevalence of HBV in the general population and associated risk factors so as to set priorities for specific prevention and control strategies in this population.</p><p><strong>Methods: </strong>This was an analytical cross-sectional study among 1399 general population aged 18 years and above who came for HBV screening during the world viral hepatitis day on 28th and 29th July 2019. Serological marker of HBV was done using Determine HBsAg 2 Rapid Test. Data were cleaned and analyzed using STATA version 15.1. Log-binomial regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for factors associated with HBV infection.</p><p><strong>Results: </strong>The mean age of all study participants was 43.3±16.1 years, 57.4% were aged 40 years and above, and 57.8% were females. The positive rate of hepatitis B surface antigen (HBsAg) was 2.4%. Significantly higher odds of HBV infection were among respondents aged 30-39 (OR=2.70, 95%CI 1.22, 5.97, p=0.01) compared to those aged 40 years and above and those with a history of HBV infection (OR=8.46, 95%CI 2.66, 26.86, p<0.001).</p><p><strong>Conclusion: </strong>The prevalence of hepatitis B infection is at an intermediate epidemic level in a semi-urban population in North-eastern Tanzania. Particular attention should be among middle-aged adults, such as those aged 30-39 years compared to their older counterparts and those with a history of HBV infection.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"30-37"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Head dimensions in children with and without cerebral palsy in Kano.","authors":"Abdulsalam Hassana, Tela Idris Abdu","doi":"10.4314/ahs.v25i2.31","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.31","url":null,"abstract":"<p><strong>Background: </strong>Cerebral palsy (CP) is a chronic motor function disorder which occurs in children.</p><p><strong>Aim: </strong>To evaluate the head dimensions in children who have CP and those without in Kano.</p><p><strong>Methodology: </strong>A cross-sectional study of 110 normal and 70 children who have CP. The age, sex, head breadths (HB), head circumferences (HC), and head lengths (HL) were obtained. The data were analyzed in Minitab 17.0 and expressed as mean ± Standard Deviation (SD). Student's -t-test and Pearson's correlations were used to determine the differences and relationships between variables. P-values <0.05 was considered significant.</p><p><strong>Results: </strong>Children without CP had significantly larger head dimensions (p < 0.05) compared to those with CP. No sexual dimorphism (p > 0.05) was observed in head dimensions for children with or without CP. In children with CP, age showed significant correlations (p < 0.05) with head dimensions, with the strongest correlation found for head circumference (p < 0.001). Head length and head breadth were significantly correlated (p < 0.001) in both groups, with a stronger correlation in children with CP.</p><p><strong>Conclusion: </strong>This study concludes that children with cerebral palsy (CP) have smaller head dimensions compared to non-CP children, however, no observed sexual dimorphism observed among the two groups.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"259-264"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alveolar ridge height changes in adults and adolescents with angle class I malocclusion before and after orthodontic treatment.","authors":"Jun Yin, Jing Li, Yue Li, Yiran Hao, Yuanyuan Li, Yancong Wen, Shixin Cai","doi":"10.4314/ahs.v25i2.30","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.30","url":null,"abstract":"<p><strong>Background: </strong>This study compared the changes in alveolar ridge height in adult and adolescent patients with Angle Class I malocclusion before and after orthodontic treatment.</p><p><strong>Methodology: </strong>A total of 110 patients, 55 adults (18 years and above) and 55 adolescents (10 to less than 18 years), were included. The research focused on alveolar bone thickness and changes in ridge height.</p><p><strong>Results: </strong>Results showed no significant differences in alveolar ridge thickness between the groups at various locations. Adults had thinner alveolar ridges at 7 mm and 9 mm compared to adolescents. Post-treatment, adults experienced increased ridge height in specific regions, while adolescents had minor changes. Some craniofacial angles and chin concavity differed between the groups. Adults exhibited a higher incidence of bone cracking, with an increase post-treatment. Adolescents didn't show significant changes in bone cracking.</p><p><strong>Conclusion: </strong>In conclusion, orthodontists should customize treatment for Angle Class I malocclusion based on age-specific findings. Adolescents may experience minor alveolar changes, while adults exhibit increased ridge height and higher fracture risk post-treatment. Monitoring and adapting plans accordingly ensure effective and safe outcomes.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"250-258"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short and Long term glycemic control among Type 2 DM patients in a resource-limited setting.","authors":"Ijeoma Angela Meka, Chika Juliet Okwor, Ekene Joy Arum, Ochuko Otokunefor, Obumneme Benneth Anyim, Michael Ikechukwu Ogamba","doi":"10.4314/ahs.v25i2.23","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.23","url":null,"abstract":"<p><strong>Background: </strong>Diabetes Mellitus is a chronic disease condition and one of public health importance in Africa and indeed globally. Its potential complications can be mitigated by tight control of blood glucose, achievable by both short and long term glucose monitoring. The values of these measures are expected to both be within target, but for some reasons, sometimes these values become discordant.</p><p><strong>Objective: </strong>This study is aimed at determining the pattern of short and long term glycemic control prevalent among Type 2 diabetic patients in the study environment and the extent of the discordance between them.</p><p><strong>Methods: </strong>A cross-sectional study carried out at University of Nigeria Teaching Hospital, Enugu. Research participants comprised consenting adults with Type 2 Diabetes Mellitus. Fasting plasma glucose and glycated hemoglobin were used to assess short and long term glycemic control respectively.</p><p><strong>Results: </strong>The study included 148 participants (60 males and 88 females). Glycated haemoglobin (HbAlc) correlated significantly with Fasting Plasma Glucose (FPG) (P < 0.00001). Prevalence of optimal long and short term glycemic control was 42.6% and 35.8% respectively. The proportion of individuals with concordance between FPG and HbA1c was 116 (78.4%) while 32 (21.6%) had discordant values.</p><p><strong>Conclusion: </strong>Glycemic control, both long and short terms, was sub-optimal among participants. Discordance observed between HbA1c and FPG creates some dilemma in clinical decision making, and calls for guidelines and uniformity in the clinical management of these conditions.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"176-185"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical profile and immediate outcomes of concurrent chemoradiation for cervical cancer at the Bugando medical centre in Mwanza, Tanzania.","authors":"Aziza Ali Haji, Edgar Ndaboine, Beda Likonda, Oscar Ottoman, Richard Kiritta, Dismas Matovelo, Richard Rumanyika, Peter Rambau","doi":"10.4314/ahs.v25i2.27","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.27","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Globally, cervical cancer poses a challenge to public health. It is the fourth most prevalent cancer diagnosed in women worldwide, with an estimated annual death rate of 311,000. It is currently the most prevalent malignant disease in Tanzania in which the majority of patients with advanced cervical cancer have been offered concurrent chemoradiation (CCR). However, neither the clinical profile nor the immediate outcomes of these patients treated at the Bugando Medical Centre (BMC) have been thoroughly studied.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methodology: &lt;/strong&gt;The prospective cohort study was conducted from November 2021 to April 2022, involving 160 eligible patients with histopathologically confirmed cervical cancer who received concurrent chemoradiation at BMC. Patients were followed for seven weeks, with the main clinical profiles of interest being age, histological type, histological tumor grade, FIGO disease stage, and HIV status, and the outcomes of interest being short-term clinical treatment-related toxicity and symptoms disappearance. The history and physical examination provided information about the patient's characteristics. Multivariate Logistic regression analysis was performed to evaluate the strength of the association between the patient's clinical profile and the short-term clinical treatment-related toxicity and symptoms disappearance. P-values less than 0.05 were considered statistically significant.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 160 cervical cancer patients eligible were enrolled, with a median age of 50 years, 117 (73.5%) living in rural areas, and 152 (95%) being illiterate or having only primary education. The most common presenting symptoms were abnormal vaginal discharge 116 (72.5%) and bleeding 111 (69.4%). 119 (74%) patients presented at a late stage (IIB-1VA), 59 (36.9%) were HIV-positive, the majority 134 (83.7%) had squamous cell carcinoma, and 91 (56,2%) had a tumor of grade II type. At week 7, 60% of patients had a complete response to treatment. Vaginal bleeding and discharge improved, with only 12.5% and 6% of women still experiencing these symptoms respectively by week 7 however, 31% of reported cases of low back pain persisted. The majority of patients experienced tolerable grade II toxicities, including diarrhea (58%), vomiting (44.3%), and skin desquamation (52.5%). Fewer study participants reported grade III toxicity, and neither grade IV toxicity nor toxicity-related deaths were reported. Age &gt; 60 years of age (OR 5.58; 95%CI 1.91-16.30; p = 0.002), late tumor stage at presentation (OR 3.36; 95%CI 1.53-7.37; p = 0.002), and HIV seropositivity (OR 11.8; 95%CI 4.87-28.6; p = 0.001) were associated with poor treatment responses.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Cervical cancer still affects the majority of middle-aged women from rural areas with low levels of education and the majority present at an advanced stage. At BMC, concurrent chemoradiation has tolerable toxicity and a ","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"218-226"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of thoracoscopic pulmonary wedge resection, thoracoscopic lobectomy and open lobectomy in patients with lung cancer.","authors":"Feibao Jiang, Deguang Pan, Yanjun Qiu","doi":"10.4314/ahs.v25i2.16","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.16","url":null,"abstract":"<p><strong>Background: </strong>To analyze the value of thoracoscopic lung wedge resection, thoracoscopic lobectomy and open lobectomy in patients with lung cancer.</p><p><strong>Methodology: </strong>Ninety-six patients with lung cancer were divided into three groups: thoracoscopic lung wedge resection (F1 group), thoracoscopic lobectomy (F2 group), and open lobectomy (F3 group). The study assessed the patients' general condition, pulmonary function, oxidative stress indicators, quality of life (EORTC QLQ-C30), and occurrence of postoperative complications, including pulmonary infections.</p><p><strong>Results: </strong>The F1 and F2 groups outperformed the F3 group in most surgical indicators, except for lymph node count. F1 group had better results than the F2 group. Pulmonary function was better in the F1 group postoperatively compared to F2 and F3 groups. F1 and F2 groups exhibited lower levels of oxidative stress indicators, while having higher levels of SOD than the F3 group. At 3 and 6 months' post-surgery, F1 group had lower EORTC QLQ-C30 scores than F2 and F3 groups. The incidence of complications, including lung infections within 6 months after surgery, was lower in F1 and F2 groups than the F3 group.</p><p><strong>Conclusion: </strong>Thoracoscopic lung wedge resection can reduce surgical trauma and oxidative stress, alleviate lung function damage and postoperative complications, and improve the level of quality of life.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"118-123"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The diagnosis of fetal micrognathia with two-dimensional and real-time three-dimensional color Doppler ultrasound.","authors":"Jing Zhong, Zeyu Deng, Xinyue Yang","doi":"10.4314/ahs.v25i2.7","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.7","url":null,"abstract":"<p><strong>Background: </strong>The study describes the diagnose of fetal micrognathia by the two-dimensional and real-time three-dimensional color doppler ultrasound, and evaluates its clinical value.</p><p><strong>Methodology: </strong>The case group comprised 100 fetuses with highly suspected mandibular deformity, and the control group consisted of 100 normal fetuses. Various ultrasonic equipments and multimedia data processing system were used to obtain 2D and 3D images of fetal mandible, and the Biparietal Diameter (BPD) and Fetal Mandibular Longitudinal Diameter (FML) were measured. The Jaw Indices (JI) and Inferior Facial Angle (IFA) were calculated, and all suspected cases underwent chromosome examination. Eight confirmed cases of mandibular deformity were identified in the case group.</p><p><strong>Results: </strong>This study examined eight cases of fetal micrognathia and found positive correlations between transverse diameters and FMLs of normal fetuses and gestational weeks. There was no significant correlation between JI, IFA, and gestational weeks. The study also compared JI, IFA, and FML between normal and small mandibular groups, finding significant differences. The smallest FML in the small mandibular group was only approximately equal to the normal fetus FML in the 18th week.</p><p><strong>Conclusion: </strong>The study provides insights into the measurement and analysis of fetal micrognathia. Combining FML, JI, and IFA with ultrasonic diagnosis reduces fetal micrognathia misdiagnosis.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"46-51"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiparametric dual-energy Computed Tomography in the diagnosis of lung adenocarcinoma patients and its correlation with tissue Ki-67 expression level.","authors":"Gang Su, Hongwei Zhao","doi":"10.4314/ahs.v25i2.38","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.38","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this study was to investigate the variations in quantitative analysis of lung adenocarcinoma based on gender using dual-energy Computed Tomography (DECT), as well as its correlation with Ki-67, a proliferative marker.</p><p><strong>Methodology: </strong>A retrospective analysis was conducted on 79 patients diagnosed with lung adenocarcinoma, categorized into two groups based on gender. These patients underwent dual-energy CT scans, and the corresponding Ki-67 index was obtained. The study involved statistical analysis of general clinical characteristics, conventional chest imaging features, and dual-energy quantitative iodine values of the lung cancer patients in each gender group. Additionally, correlation analysis was performed to assess the relationship between the statistically significant parameters and Ki-67.</p><p><strong>Results: </strong>A significant disparity was observed in the values of virtual non-contrast (VNC) and Ki-67 between male and female patients with lung adenocarcinoma. Notably, male patients exhibited lower iodine concentration and a smaller increase in iodine value. Several quantitative iodine parameters showed a correlation with Ki-67. Among these parameters, OVERLAY_VP exhibited the strongest correlation. Distinct quantitative iodine parameters were identified for male and female lung adenocarcinoma patients, which exhibited a correlation with Ki-67, thereby facilitating the evaluation of the proliferative activity of lung adenocarcinoma.</p><p><strong>Conclusion: </strong>Dual-energy quantitative iodine parameters in lung adenocarcinoma patients exhibited gender-specific variations.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"320-329"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical observation of anterior decompression bone grafting and internal fixation in the treatment of lower cervical dislocation and analysis of influencing factors of early postoperative complications.","authors":"Yongjun Meng, Zhichao Gao, Xiaoliang Qian, Jian Luo, Xiaodong Chu","doi":"10.4314/ahs.v25i2.32","DOIUrl":"https://doi.org/10.4314/ahs.v25i2.32","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of anterior decompression with bone graft and internal fixation for dislocation of lower cervical vertebra, and to analyze the influencing factors of early postoperative complications.</p><p><strong>Methods: </strong>The retrospective study included 90 patients with lower cervical fractures and dislocations who received anterior decompression and internal fixation in our hospital from November 2018 to October 2021. Postoperative indexes, therapeutic effects, postoperative recovery of cervical and spinal functions and complications were observed. Univariate and multivariate Logistic regression analysis was conducted with early postoperative complications as the dependent variable.</p><p><strong>Results: </strong>All the 90 patients underwent surgical treatment successfully, the operation time was (85.11 ± 11.57) min, the intraoperative blood loss was (148.05±36.75) mL. Compared with preoperative results, Cobb Angle and anterior atlas space were significantly smaller at 6 months and 1 year after surgery (P < 0.05). No broken plate, broken nail and loose plate were observed in the patient one year after surgery, and the bone graft fusion was good. JOA score and ASIA score were significantly improved at 6 months and 1 year after surgery (P < 0.05). ASIA scores of patients with incomplete nerve injury were improved in different degrees 6 months and 1 year after surgery (P < 0.05). Of the 90 patients, 10 had related complications after surgery, with an incidence of 11.11%. The results of multivariate Logistic regression analysis indicated that the time from injury to operation and the longer operation time were both influencing factors of early postoperative complications (P < 0.05).</p><p><strong>Conclusion: </strong>Anterior cervical approach decompression bone grafting and internal fixation in the treatment of lower cervical fracture and dislocation has remarkable effects, which is helpful to promote the recovery of spinal nerve function. However, postoperative complications still exist, among which the time from injury to operation and the longer the operation time are both influencing factors of early postoperative complications, which should be paid attention to in clinic.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"25 2","pages":"265-273"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}