African health sciences最新文献

{"title":"A cellular schwannoma of the nasal septum: a case report.","authors":"A K Al-Balasi, O M El Mustafa, A M El Hassan","doi":"10.4314/ahs.v24i4.33","DOIUrl":"10.4314/ahs.v24i4.33","url":null,"abstract":"<p><strong>Background: </strong>Cellular schwannoma is a benign variant of classic schwannomas. It is an extremely rare condition to be derived from nasal septum.</p><p><strong>Case presentation: </strong>a cellular schwannoma of the nasal septum is described in a 10-year-old Sudanese girl presented with nasal obstruction. The tumor was treated surgically by a trans-nasal approach. Pathological examination of the resected tumor showed cellular schwannoma. The tumor cells were immunoreactive for S-100 protein. The patient has been doing well for 10 months with no evidence of tumor recurrence.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"258-261"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic task shifting for NTDs: outcome of a preliminary quasi-experimental study for microfilaria detection using a novel diagnostic device in Nigeria.","authors":"Adeola Onasanya, Temitope Agbana, Opeyemi Oladunni, Jo Van Engelen, Oladimeji Oladepo, Jan Carel Diehl","doi":"10.4314/ahs.v24i4.7","DOIUrl":"10.4314/ahs.v24i4.7","url":null,"abstract":"<p><strong>Background: </strong>Lymphatic filariasis (LF) is a Neglected Tropical Disease (NTD) with high morbidity. Tools for detecting LF are either not readily available or used by Community Health Extension Workers (CHEWs) at Primary Health Centers. A newly developed diagnostic device, the AiDx Assist, is targeted for use by CHEWs.</p><p><strong>Objective: </strong>The study aims to determine the efficiency (speed) and effectiveness (diagnostic capacity) of CHEWs compared to laboratory scientists for detecting LF with the new device, using the World Health Organization's Target Product Profile (TPP) for LF diagnostics as a guide.</p><p><strong>Methods: </strong>This study utilized a Quasi-experimental design. 7 students undergoing the CHEW program (intervention group) were randomly selected while 2 laboratory scientists (control group) were purposively recruited and were trained to use the device. Thereafter, both groups were tested based on 64 sample slides provided.</p><p><strong>Results: </strong>The intervention group's efficiency (speed) was similar to the control group. Computed Effectiveness (diagnostic capacity) parameters for the intervention group demonstrated a sensitivity of 85.7% and a specificity of 82.5%.</p><p><strong>Conclusion: </strong>Given this preliminary result, task shifting to CHEWs for the diagnosis of LF is highly likely to be successful, thereby reducing the prevalence of LF in low-resource settings.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"43-50"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect analysis of entecavir on serum hyaluronic acid, laminin and IV collagen in the treatment of hepatitis B E-antigen-positive chronic hepatitis B.","authors":"Jiancheng Qian, Xiaoyong Sun, Yue Cheng","doi":"10.4314/ahs.v24i4.6","DOIUrl":"10.4314/ahs.v24i4.6","url":null,"abstract":"<p><strong>Background: </strong>To observe and analyse the clinical effects of entecavir on serum hyaluronic acid (HA), laminin (LN), and type IV collagen (IVC) in patients with hepatitis B e-antigen (HBeAG)-positive chronic hepatitis B during clinical treatment.</p><p><strong>Methodology: </strong>The patients in the control group received clinical treatment with entecavir monotherapy, while those in the observation group underwent thymalfasin + entecavir combination therapy. The clinical curative effects of immune checkpoint inhibitors at different concentrations on diseases were compared from all aspects.</p><p><strong>Results: </strong>There were lower levels of total bilirubin (TBIL) and alanine transaminase (ALT) in the observation group, a more satisfactory improvement in immune function-related indicators, and lower levels of HA, LN, and IVC in the observation group, which were statistically different between the two groups (P<0.05). The levels of liver function indicators, immune function-related indicators (CD3+, CD4+, CD8+, CD4+/CD8+, CD4+/CD8+), and HA, LN and IVC were not statistically different between the two groups before treatment.</p><p><strong>Conclusion: </strong>Entecavir is highly effective in the clinical treatment of HBeAG-positive chronic hepatitis B. However, entecavir + thymalfasin combination therapy can alleviate the clinical symptoms. In this way, liver fibrosis can be prevented in patients with HBeAG-positive chronic hepatitis B, and the clinical curative effect can be enhanced.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"38-42"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of febuxostat in different doses on uric acid, inflammatory factors of serum and knee articular cavity, endothelin-1, and oxidative stress in patients with a gout-a comparative study.","authors":"Ning Tie, Lijie Bai, Hongbin Li, Dafu Man, Lei Wang, Xinlu Zhou, Yong Wang","doi":"10.4314/ahs.v24i4.40","DOIUrl":"10.4314/ahs.v24i4.40","url":null,"abstract":"<p><strong>Objective: </strong>The present comparative study aimed to investigate the effects of different doses of febuxostat on uric acid, inflammatory factors of serum, knee articular cavity, endothelin-1, and oxidative stress in patients with gout.</p><p><strong>Methods: </strong>80 cases with hyperuricemia admitted to our hospital (January 2018- March 2020) were randomly distributed into two groups. The control group was administered 40 mg of febuxostat tablets daily., whereas the treatment group was administered febuxostat tablets 80 mg daily. Data were collected from two groups of patients, including uric acid level, TNF-α levels of serum and knee articular cavity, vascular endothelial function, and complications 1 month after the intervention.</p><p><strong>Results: </strong>After data intervention, the levels of uric acid, TNF-α levels of serum, and knee articular cavity, NO, and SOD were significantly different between the treatment group and the control group (each p< 0.05). There were no significant differences in abdominal pain and diarrhea, liver damage, kidney damage, acute gout, and pruritus between the two groups (p >0.05). The duration of activity disorder, pain duration, and swelling in the treatment group were significantly shorter than those in the control group (p< 0.05). The uric acid level was positively correlated with serum TNF-α level (p < 0.05), and negatively correlated with NO and SOD levels (p < 0.05).</p><p><strong>Conclusion: </strong>For hyperuricemia-induced gout patients, taking a large dose of 80 mg febuxostat daily can significantly reduce the uric acid level and inflammatory response, improve vascular endothelial function, enhance antioxidant ability, and improve the clinical symptoms of patients without increasing the adverse reactions to medication.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"313-324"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual behaviour and condom use of older adults living with HIV/AIDS in a treatment centre at Osogbo, south-west Nigeria.","authors":"Samuel Anu Olowookere, David Ayobami Adewole, Omowonuola Olubukola Sonibare, Amos Akindele Ajayi, Ebenezer Gbenga Adepoju, Olumayowa Abimbola Oninla, Olubukunola Omobuwa, Emmanuel Oladayo Folami","doi":"10.4314/ahs.v24i4.20","DOIUrl":"10.4314/ahs.v24i4.20","url":null,"abstract":"<p><strong>Objective: </strong>This study assessed the condom use and sexual behaviour of older adults living with HIV/AIDS at Osogbo, Osun State, Nigeria.</p><p><strong>Methods: </strong>A descriptive cross-sectional study involving all adults receiving care at an HIV treatment centre that completed an interviewer administered questionnaire on their sexual behaviour and condom use. Data were analyzed using descriptive and inferential statistics.</p><p><strong>Results: </strong>A total of 186 older adults completed the study. Their mean age (SD) was 54.5 (5.6) years. There are 114 (61.3%) females and 72 (38.7%) males. Two fifth 87 (46.8%) were sexually active with over half using condom (45, 51.7%) at last sexual intercourse. The determinants of condom use at last sexual intercourse included age 50-59 years (OR=3.34, 95% CI=1.21-9.25, p=0.020), lower education (OR=3.00, 95%CI=1.04-8.69, p=0.043), being married or have a partner (OR=3.25, 95%CI=1.11-9.52, p=0.031), partner's awareness of respondents' HIV status (OR=13.00, 95%CI=4.25-39.80, p<0.0001) and stigma experience from partner (OR=11.70, 95%CI=4.03-33.99, p=0.0001).</p><p><strong>Conclusion: </strong>Older adults engage in high-risk sexual behaviour. It is necessary to encourage safer sex practices, stigma reduction and couple HIV counseling and testing.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"149-155"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"System-level barriers account for non-compliance to physiotherapy among persons with Parkinson's disease at the Korle Bu Teaching Hospital, Ghana: an explanatory mixed-method study.","authors":"Mary W Agoriwo, Pascal G Adorvlo, Peter Oppong Junior, Ellen Mensa-Bonsu, Martin Ackah, Benedicta Atsivor","doi":"10.4314/ahs.v24i4.42","DOIUrl":"10.4314/ahs.v24i4.42","url":null,"abstract":"<p><strong>Background: </strong>Despite the increasing importance of physiotherapy and robust evidence, there is still limited studies assessing compliance rates and barriers to physiotherapy appointments for Persons with Parkinson disease (PwPD) especially in low-resource settings such as Ghana.</p><p><strong>Objective: </strong>To assess compliance rates and identify barriers to adhering to physiotherapy appointments among PwPD receiving physiotherapy management at a tertiary hospital in Ghana.</p><p><strong>Methods: </strong>A sequential explanatory mixed method design was used. The quantitative part involved a retrospective survey of health records of PwPD who reported at the Korle-Bu teaching hospital physiotherapy PD-clinic from 2013-2021. The qualitative part involved semi-structured telephone interviews among defaulters from the year with highest clinic attendance. Quantitative data was descriptively analyzed. For the qualitative data, a deductive qualitative content analysis of the transcribed audiotaped interviews was conducted.</p><p><strong>Results: </strong>Eighty-six PD records (56 males) were included. Overall mean (SD) age was 67(±11) and ranged from 38-90 years. The year 2014 recorded the highest number of attendees (n=20/86; 23%). Overall, 88% of the participants had stopped physiotherapy. Six PwPD participated in the interviews. System-level barriers were mainly recorded as the reasons for patients defaulting physiotherapy.</p><p><strong>Conclusion: </strong>The majority of PwPD had stopped physiotherapy and system-level barriers were the key reasons.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"332-342"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of radio-frequency ablation in treating pulmonary ground glass nodule patients and its influence on pulmonary function.","authors":"Chengwei Zhou, Zixuan Chen, Yuan Zhang, Xiaodong Zhao","doi":"10.4314/ahs.v24i4.32","DOIUrl":"10.4314/ahs.v24i4.32","url":null,"abstract":"<p><strong>Background: </strong>With widespread application of low-dose thin-section chest CT screening, the detection rate of patients with subsolid nodules (SNs) as CT findings has increased remarkably.</p><p><strong>Objective: </strong>To clarify effect of radio-frequency ablation (RFA) in treating pulmonary ground glass nodule (GGN) patients and its impact on pulmonary function.</p><p><strong>Methods: </strong>A total of 100 patients diagnosed with pulmonary GGN in our hospital from January 2019 to December 2021 by pulmonary thin-section CT + enhanced imaging examination and all underwent simultaneous needle biopsy were enrolled and randomly divided into control group and observation group, with 50 cases each. The control group received treatment with traditional surgery. The observation group received treatment with RFA. The surgical indicators, surgical treatment efficacy, levels of inflammatory cytokines, complications and pulmonary function indicators were assessed between two groups.</p><p><strong>Results: </strong>The operation time, hospital stay and intraoperative blood loss in observation group were markedly shorter/less than controls (P < 0.05). No residual recurrence was observed in total 84 nodules of 50 cases in observation group. The size of nodules was observed by CT 1, 3 and 6 months after operation. With prolongation of postoperative time, nodules gradually shrank, after 6 months, fibrous cord scar residue gradually formed, with statistical significance relative to those before operation (P < 0.05). The postoperative IL-6, CRP and TNF-α in both groups presented elevation, whereas postoperative changes in IL-6, CRP and TNF-α in observation group presented depletion relative to control group, with statistical significance (P < 0.05). The complication rate in observation group presented depletion relative to control group, with statistical significance (P < 0.05). The FVC, FEV1, FEV1%, MVV and PEF in both groups presented depletion 1 month after operation and presented statistical significance relative to those before operation except for FEV1% (P < 0.05), and changes in observation group presented depletion relative to control group. Six months after operation, FVC, FEV1, FEV1%, MVV and PEF in both groups had recovered to preoperative levels and presented no difference relative to preoperative level (P > 0.05), and presented no difference between two groups (P > 0.05).</p><p><strong>Conclusion: </strong>RFA for the therapy of pulmonary GGN is safe and effective, without surgical scar, and is less traumatic to the body, which has a good application prospect.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"250-257"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of the begining time of the rehabilitation program in stroke patients on functional ambulation and stroke related complications.","authors":"Gülseren Demir Karakılıç, Esra Şahingöz Bakırcı, Ferda Büyük","doi":"10.4314/ahs.v24i4.35","DOIUrl":"10.4314/ahs.v24i4.35","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to reveal the effect of rehabilitation initiation time on the functional status and complications encountered during the rehabilitation process in stroke patients who underwent rehabilitation program in the physical medicine and rehabilitation clinic of our hospital.</p><p><strong>Material and methods: </strong>Patients who received outpatient and inpatient rehabilitation treatment with the diagnosis of acute stroke in the Physical Medicine and Rehabilitation Clinic of Yozgat City Hospital between January 2017 and August 2022 were screened. Patients with acute stroke and had a file record were included in the study.Demographic information such as age, gender, comorbid diseases; type and direction of stroke, time from stroke until the rehabilitation program begins, total rehabilitation period, stroke-related complications, Brunnstrom stages, and functional ambulation scale scores of stroke patients were recorded.</p><p><strong>Results: </strong>A total of 314 patients were included in this study and evaluated improvement in the functional ambulation scale scores according to the beginning time of the rehabilitation program. When the patients were grouped as 0-30 days, 31-60 days, and 61 days or more according to the time elapsed until the rehabilitation program, a significant difference was found in terms of the increase in FAS scores both in the pairwise comparisons and the comparison of all three groups together (p<0.001 for all comparisons). There was a moderate positive correlation between the total number of rehabilitation sessions and improvement in FAS scores (Rho=.316, p<0.01). Complications were observed in almost all patients in our study (97.7%). The comparison of the groups for stroke complications revealed that the frequency of depression, urinary tract infection, urinary incontinence, decubitus ulcer, dysphagia, convulsion, falling and aphasia was lower in the 0-30 days group compared to the other groups (p<0.01). There was also no significant correlation between the presence of stroke complications and improvement in FAS score (p>0.05).</p><p><strong>Conclusion: </strong>Contrary to popular belief, we showed that early rehabilitation does not increase complications and has a positive effect on function. Despite the perception that complications would negatively affect function, there was no significant relationship between the presence of stroke complications and the improvement in FAS score. We found that the rehabilitation program applied in the early period after stroke is effective and reliable.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"269-275"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of hearing loss among primary school children in Ethiopia.","authors":"Robbert Ensink, Amber Morgan, Alden Smith, Margaretha Casselbrant, Nyasha Makaruse, Glenn Isaacson","doi":"10.4314/ahs.v24i4.54","DOIUrl":"10.4314/ahs.v24i4.54","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to determine the prevalence of hearing loss in children attending primary schools in urban and rural Ethiopia.</p><p><strong>Methods: </strong>A cross-sectional study was performed to determine the prevalence of hearing loss in children aged 7 to 14 years. A total of 384 children had complete examinations and were included in the study.</p><p><strong>Results: </strong>The prevalence of hearing loss of all types in the urban school was 6.2% using a cut-off of 40 dB Fletcher index (500-2000 Hz). The prevalence increased to 10.2 % in the same population if a cut-off of 25 dB HL FI was used. In the rural school with a cut-off of 30 dB HL the hearing prevalence was 5.9%. The proportion of conductive hearing loss was lower in the urban school and constituted 16% of all hearing losses. We estimated the proportion of conductive hearing loss in the rural school to be at least 50%. In the urban school the prevalence of sensorineural hearing loss was 5.8% while it was much lower at 1.3% and exclusively unilateral in the rural school. The degree of hearing loss according to WHO criteria was calculated only for the urban population. A prevalence of bilateral severe hearing loss (≥61 dB HL) of 0.5% and of moderate hearing loss (> 41 dB and ≤60dB HL) of 1% was found using WHO criteria.The prevalence of chronic suppurative otitis media and of dry perforations were similar between schools (2.5 to 2.7%). Otitis media was rare in this study likely due to seasonal influences and exclusion of very young children. These results are compared to similar school studies in Sub-Saharan Africa.</p><p><strong>Conclusions: </strong>The prevalence of hearing loss in these two Ethiopian cohorts (rural and urban) is in agreement with the data published by WHO for Sub-Saharan Africa. While some of the variation between urban and rural populations may have been real, some of the discrepancy may have resulted from differences in acoustic testing environments. We describe these challenges in hopes of improving universal screening procedures.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"438-448"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effect of a novel nursing intervention in the treatment of vacuum sealing drainage in patients with chronic orthopedic wounds.","authors":"Lan Chen, Dong Li, Xiaodong Lei, Bixia Zhou, Lili Chen","doi":"10.4314/ahs.v24i4.13","DOIUrl":"10.4314/ahs.v24i4.13","url":null,"abstract":"<p><strong>Background: </strong>To explore the application effect of \"4+1\" nursing intervention in the treatment of chronic orthopaedic trauma with negative pressure vacuum sealing drainage.</p><p><strong>Methodology: </strong>Patients before the implementation of the \"4+1 nursing intervention\" program were selected as the control group (60 cases). 60 patients after the implementation of the \"4+1 nursing intervention\" program were selected as the research group. Control group was given routine care. Research group adopted the \"4+1\" nursing intervention. Hamilton Depression score, wound healing time, pain visual analogue scale, treatment compliance, Self-Rating Anxiety Scale, and nursing satisfaction were compared between the two groups.</p><p><strong>Results: </strong>After the intervention, the Self-Rating Anxiety Scale and Hamilton Depression scores in the study group were lower than those in the control group; visual analogue scale on the 3rd and 5th days after the study were lower than those in the control group, and the wound healing time was shorter than that in the control group. The treatment compliance rate and nursing satisfaction of the study group were higher than those of the control group (P<0.05).</p><p><strong>Conclusion: </strong>The application of \"4 + 1\" nursing intervention in treatment of orthopaedic chronic wounds has a good effect.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"99-105"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}