Analysis of thoracoscopic pulmonary wedge resection, thoracoscopic lobectomy and open lobectomy in patients with lung cancer.

Abstract

Background: To analyze the value of thoracoscopic lung wedge resection, thoracoscopic lobectomy and open lobectomy in patients with lung cancer.

Methodology: Ninety-six patients with lung cancer were divided into three groups: thoracoscopic lung wedge resection (F1 group), thoracoscopic lobectomy (F2 group), and open lobectomy (F3 group). The study assessed the patients' general condition, pulmonary function, oxidative stress indicators, quality of life (EORTC QLQ-C30), and occurrence of postoperative complications, including pulmonary infections.

Results: The F1 and F2 groups outperformed the F3 group in most surgical indicators, except for lymph node count. F1 group had better results than the F2 group. Pulmonary function was better in the F1 group postoperatively compared to F2 and F3 groups. F1 and F2 groups exhibited lower levels of oxidative stress indicators, while having higher levels of SOD than the F3 group. At 3 and 6 months' post-surgery, F1 group had lower EORTC QLQ-C30 scores than F2 and F3 groups. The incidence of complications, including lung infections within 6 months after surgery, was lower in F1 and F2 groups than the F3 group.

Conclusion: Thoracoscopic lung wedge resection can reduce surgical trauma and oxidative stress, alleviate lung function damage and postoperative complications, and improve the level of quality of life.