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Ethical, medico-legal and financial aspects of the legalization of surrogate maternity in Bulgaria. 保加利亚代孕合法化的伦理、医法和财政问题。
African health sciences Pub Date : 2024-12-01 DOI: 10.4314/ahs.v24i4.19
A Mihaylova, D Bakova, D Davcheva, A Yaneva, D Shopova, S Harizanova, N Parahuleva, M Semerdzhieva
{"title":"Ethical, medico-legal and financial aspects of the legalization of surrogate maternity in Bulgaria.","authors":"A Mihaylova, D Bakova, D Davcheva, A Yaneva, D Shopova, S Harizanova, N Parahuleva, M Semerdzhieva","doi":"10.4314/ahs.v24i4.19","DOIUrl":"10.4314/ahs.v24i4.19","url":null,"abstract":"<p><p>The legalization of surrogacy and reproductive choices is a possible solution for childless families and the specialists in this area prove that this is a great challenge and responsibility. There are many issues on the topic: medical, ethical, as well as socio-psychological, legal and financial. The aim of present survey is to study and analyse the attitudes of society regarding some medical, social and economic and law aspects related to the legalization of surrogate maternity in Bulgaria. An anonymous survey was conducted involving 387 people. The data was collected via a pen and paper questionnaire pack. The initiative has provoked wide public interest. According to the participants in the present study, in the event of it being legalized, surrogate maternity should not become a profession, a source of surplus income for the surrogate mother, but the costs directly related to the pregnancy, birth and postpartum recovery should be compensated. The rights of the surrogate mother regarding custody of the child after birth and abortion rights should be limited in favor of the intended parents. The aspects discussed concern only the projected legal framework of surrogate maternity in Bulgaria, because at the present, the Bill has not been adopted.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"143-148"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the effect of a novel nursing intervention in the treatment of vacuum sealing drainage in patients with chronic orthopedic wounds. 一种新型护理干预在慢性骨科伤口真空密封引流治疗中的效果评价。
African health sciences Pub Date : 2024-12-01 DOI: 10.4314/ahs.v24i4.13
Lan Chen, Dong Li, Xiaodong Lei, Bixia Zhou, Lili Chen
{"title":"Evaluation of the effect of a novel nursing intervention in the treatment of vacuum sealing drainage in patients with chronic orthopedic wounds.","authors":"Lan Chen, Dong Li, Xiaodong Lei, Bixia Zhou, Lili Chen","doi":"10.4314/ahs.v24i4.13","DOIUrl":"10.4314/ahs.v24i4.13","url":null,"abstract":"<p><strong>Background: </strong>To explore the application effect of \"4+1\" nursing intervention in the treatment of chronic orthopaedic trauma with negative pressure vacuum sealing drainage.</p><p><strong>Methodology: </strong>Patients before the implementation of the \"4+1 nursing intervention\" program were selected as the control group (60 cases). 60 patients after the implementation of the \"4+1 nursing intervention\" program were selected as the research group. Control group was given routine care. Research group adopted the \"4+1\" nursing intervention. Hamilton Depression score, wound healing time, pain visual analogue scale, treatment compliance, Self-Rating Anxiety Scale, and nursing satisfaction were compared between the two groups.</p><p><strong>Results: </strong>After the intervention, the Self-Rating Anxiety Scale and Hamilton Depression scores in the study group were lower than those in the control group; visual analogue scale on the 3rd and 5th days after the study were lower than those in the control group, and the wound healing time was shorter than that in the control group. The treatment compliance rate and nursing satisfaction of the study group were higher than those of the control group (P<0.05).</p><p><strong>Conclusion: </strong>The application of \"4 + 1\" nursing intervention in treatment of orthopaedic chronic wounds has a good effect.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"99-105"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Male adolescents' (Aged 15-24 years) smoking habit and its determinant: analysis of Indonesia demographic and health survey data, 2017. 男性青少年(15-24岁)吸烟习惯及其决定因素:2017年印度尼西亚人口与健康调查数据分析
African health sciences Pub Date : 2024-12-01 DOI: 10.4314/ahs.v24i4.45
Diana Rohmandani Putri, Erni Astutik, Putri Bungsu Machmud, Tika Dwi Tama
{"title":"Male adolescents' (Aged 15-24 years) smoking habit and its determinant: analysis of Indonesia demographic and health survey data, 2017.","authors":"Diana Rohmandani Putri, Erni Astutik, Putri Bungsu Machmud, Tika Dwi Tama","doi":"10.4314/ahs.v24i4.45","DOIUrl":"10.4314/ahs.v24i4.45","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to examine the factors influencing cigarette consumption among male adolescents aged 15-24 years in Indonesia.</p><p><strong>Methods: </strong>This study used the Indonesia Demographics and Health Survey 2017, which included 8,488 male adolescents aged 15-24 years. The survey used multi-stage cluster sampling. Data were analyzed by using multivariable logistic regression adjusted for covariates and a complex survey design.</p><p><strong>Results: </strong>There is 70.4% of male adolescents who smoke any tobacco products daily or occasionally. The male adolescents who aged 20-24 years (p<0.001; AOR=2.26, 95%Cl=1.96-2.59), had low education level (p<0.001; AOR=5.90, 95%Cl=3.91-8.92), start smoking at 18-24 years (p-value<0.001; AOR=3.09, 95%Cl=2.25-4.23), had been influenced by friend/someone to smoke (p<0.001; AOR=5.60, 95%Cl=4.77-6.58), used the internet at least once a week (p<0.001; AOR=1.28, 95%Cl=1.11-1.49), did not read newspaper/magazine (p<0.001; AOR=1.55, 95%Cl=1.28-1.87) had a higher odds of current smoking.</p><p><strong>Conclusions: </strong>Factors of smoking tobacco, such as age, age at first smoking, low education, the influence of smoking, and access to information on the internet and newspapers/magazines, had a significant impact on the current tobacco of male adolescents. Our findings support the enforcement of health warnings and laws related to tobacco restrictions for adolescents.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"362-372"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pattern and determinants of endometrial thickness among asymptomatic postmenopausal women in an African population. 非洲绝经后无症状妇女子宫内膜厚度的模式和决定因素。
African health sciences Pub Date : 2024-12-01 DOI: 10.4314/ahs.v24i4.17
Tola Y Bakare, Adegboyega A Fawole, Kikelomo T Adesina, Hadijat O Raji, Bola B Olafimihan, Abiodun S Adeniran
{"title":"Pattern and determinants of endometrial thickness among asymptomatic postmenopausal women in an African population.","authors":"Tola Y Bakare, Adegboyega A Fawole, Kikelomo T Adesina, Hadijat O Raji, Bola B Olafimihan, Abiodun S Adeniran","doi":"10.4314/ahs.v24i4.17","DOIUrl":"10.4314/ahs.v24i4.17","url":null,"abstract":"<p><strong>Background: </strong>The occurrence of endometrial cancer may be on the increase among African population due to lifestyle changes. Measurement of endometrial thickness (ET) in postmenopausal women may enhance timely diagnosis of endometrial pathology to improve prognosis and quality of life.</p><p><strong>Objectives: </strong>To determine the relationship between anthropometric measurements hypertension and diabetes mellitus on ET.</p><p><strong>Methods: </strong>A cross-sectional study conducted at the outpatient clinics of a tertiary facility among asymptomatic postmenopausal women (no malignancy, abnormal vaginal bleeding or hormone replacement therapy). Participants recruited by purposive sampling were sub-categorized into those with chronic hypertension, diabetes mellitus or no chronic medical disorder. All participants had anthropometric measurements, fasting blood glucose and transvaginal ultrasonography. The main outcome measure was the ET while p-value <0.05 was significant.</p><p><strong>Results: </strong>The mean ET was 2.17±2.57 and prevalence of ET (>5mm) was 1.1%. Mean ET was significantly higher among women <5 years post-menopause (2.53±1.61 vs. 2.06±2.79; P0.048); chronic hypertension (2.82±4.07mm vs. 1.42±1.16mm; P0.026) or diabetes mellitus (2.27±1.08mm vs. 1.42±1.16; P0.005). Parity was inversely related to ET (P0.005); body mass index (P0.191), duration of hypertension (P0.213) or diabetes mellitus (P0.085) were not statistically significant.</p><p><strong>Conclusion: </strong>Parity, number of years post-menopause, hypertension and diabetes mellitus were important determinants of ET.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"129-136"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The practice and effect of multi-disciplinary cooperative mobile devices in improving the satisfaction of inpatients on drug education. 多学科合作移动设备提高住院患者药物教育满意度的实践与效果。
African health sciences Pub Date : 2024-12-01 DOI: 10.4314/ahs.v24i4.48
Shuangai Zhu, Chen Huang, Xiaoyun Hu, Yulan Xu, Lili Cheng, Hongying Pan
{"title":"The practice and effect of multi-disciplinary cooperative mobile devices in improving the satisfaction of inpatients on drug education.","authors":"Shuangai Zhu, Chen Huang, Xiaoyun Hu, Yulan Xu, Lili Cheng, Hongying Pan","doi":"10.4314/ahs.v24i4.48","DOIUrl":"10.4314/ahs.v24i4.48","url":null,"abstract":"<p><strong>Objective: </strong>To explore the effect of multi-disciplinary cooperative mobile device-assisted drug education on the satisfaction of inpatients drug education.</p><p><strong>Methods: </strong>Mobile nursing vehicle, IPAD, and mobile phone were used to scan QR code to play drug propaganda videos and distribute drug propaganda materials. Doctors, nurses and pharmacists cooperated to complete drug education for inpatients. The satisfaction on drug education of inpatients was collected through a third-party satisfaction survey.</p><p><strong>Results: </strong>Before implementation, the four satisfactions of communicating about the drug, understanding the purpose of the drug, informing the role of the drug and informing the side effect of the drug were 83.9%, 80.4%, 83.8% and 83.9%, respectively, and after the implementation increased to 88.2%, 86.4%, 89.6% and 87.3% (P<0.05). The effective rate of drug education among inpatients increased from 95% before the implementation to 99.4%, and the medication compliance of inpatients increased from 93.1% before the implementation to 98.75%.</p><p><strong>Conclusion: </strong>Multi-subject cooperative mobile device-assisted drug education can improve the satisfaction of inpatients drug education, the efficiency of drug education and drug compliance.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"389-394"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sero-prevalence of Hepatitis B and C at a Primary Health Care Facility in Ghana. 加纳一家初级卫生保健机构乙型和丙型肝炎的血清患病率。
African health sciences Pub Date : 2024-12-01 DOI: 10.4314/ahs.v24i4.5
Madison Adanusa, George Adjei, Sebastian Eliason, Samuel Amoah, Benson Cecil, Ignatius Sirikyi, Faustina Pappoe, Anasthasia Ofori, Frederick Adjei, Bernice Appau, Benjamin Nyane, Arthur Rudolf, Hagan Oheneba
{"title":"Sero-prevalence of Hepatitis B and C at a Primary Health Care Facility in Ghana.","authors":"Madison Adanusa, George Adjei, Sebastian Eliason, Samuel Amoah, Benson Cecil, Ignatius Sirikyi, Faustina Pappoe, Anasthasia Ofori, Frederick Adjei, Bernice Appau, Benjamin Nyane, Arthur Rudolf, Hagan Oheneba","doi":"10.4314/ahs.v24i4.5","DOIUrl":"10.4314/ahs.v24i4.5","url":null,"abstract":"<p><strong>Background: </strong>The advent of emerging global infections such as SARS-CoV-2 has brought forth the public health crises of neglected diseases in the LMICs. Viral hepatitis infections remain a public health problem especially in the advent of emerging. Viral hepatitis which preponderantly afflicts citizens of LMICs is one such group of diseases which exerts considerable burden in these countries, especially, hepatitis B and C. There is an effective vaccine against Hepatitis B and curative treatment to hepatitis C, however, access has been hampered resulting in deleterious sequalae. Identifying population afflicted by these infections could lead to prevention of the complications.</p><p><strong>Materials and methods: </strong>Retrospective review of electronic data on individuals screened for hepatitis B and C at the University of Cape Coast Hospital were abstracted. Data abstracted included hepatitis B and C test status, age, sex, previous immunisation history and region of residence. Overall prevalence and prevalence in different categories were calculated.</p><p><strong>Results: </strong>Data for 6,006 were collected and used for the analyses. The overall prevalence for hepatitis B in the study group was 5.06%. The prevalence for hepatitis C was 0.93%.</p><p><strong>Conclusion: </strong>The burden of hepatitis B and C infection in Ghana is still high.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"29-37"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genomic variations in Mycobacterium tuberculosis from the lungs and blood of HIV-infected individuals in Uganda: insights into compartmentalization. 乌干达艾滋病病毒感染者肺部和血液中结核分枝杆菌的基因组变异:对区隔的见解。
African health sciences Pub Date : 2024-12-01 DOI: 10.4314/ahs.v24i4.2
Hellen Nakabuye, Dickson Aruhomukama, Ronald Galiwango, David P Kateete
{"title":"Genomic variations in Mycobacterium tuberculosis from the lungs and blood of HIV-infected individuals in Uganda: insights into compartmentalization.","authors":"Hellen Nakabuye, Dickson Aruhomukama, Ronald Galiwango, David P Kateete","doi":"10.4314/ahs.v24i4.2","DOIUrl":"10.4314/ahs.v24i4.2","url":null,"abstract":"<p><p>Mycobacterium tuberculosis (MTB) clinical strains are relatively varied at the genome level. This in-silico study analyzed genomic differences between MTB isolates from the blood and lungs of TB-HIV positive cohorts in Uganda. The hypothesis was that isolates from the blood have distinct SNPs and INDELs that make them better survivors. Twenty-four MTB-blood and -lung sequences were aligned against the H37Rv reference genome and analyzed using BWA-MEM, IGV, SAMtools, FreeBayes, and SnpEff. Comparative analysis revealed that MTB-blood isolates had 11 virulence genes with distinctive non-synonymous SNPs involved in increasing colony-forming units, lowering host survival, enhancing tissue pathology, and allowing for human host persistence. The majority of INDELs were found in non-virulence genes, with the remainder in both MTB-blood and -lung sequences. The study suggests that MTB-blood isolates have distinctive SNPs that explain their capacity to persist outside of the lungs. However, further research is needed to understand the significance of these SNPs in the pathogenesis of MTB.</p><p><strong>Impact: </strong>Mycobacterium tuberculosis (MTB) clinical strains have high genomic variability, and there is a knowledge gap on the genomic differences between MTB isolates from the blood and lungs of TB-HIV positive patients in Uganda. This study found that MTB-blood isolates had 11 virulence genes with distinctive non-synonymous SNPs that may contribute to their capacity to persist outside of the lungs. These findings provide insight into the genomic basis of MTB adaptation in different host environments, but further research is needed to fully understand the significance of these SNPs in MTB pathogenesis.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alleviation of nephropathy during aging as complications of diabetic by natural products. 减轻衰老期间肾病作为糖尿病并发症的天然产物。
African health sciences Pub Date : 2024-12-01 DOI: 10.4314/ahs.v24i4.49
Rami M Mosaoa, Taha A Kumosani, Soonham S Yaghmoor, Said S Moselhy
{"title":"Alleviation of nephropathy during aging as complications of diabetic by natural products.","authors":"Rami M Mosaoa, Taha A Kumosani, Soonham S Yaghmoor, Said S Moselhy","doi":"10.4314/ahs.v24i4.49","DOIUrl":"10.4314/ahs.v24i4.49","url":null,"abstract":"<p><strong>Background: </strong>The most complications of chronic diseases as diabetic during aging is micro and microvascular disorders. Consumption of functional foods is very important in protection from these complications. We studied the impact of dipeptide anserine in combination with vitamin E in prevention diabetic nephropathy in diabetic rats.</p><p><strong>Methods: </strong>The study included 60 male albino rats sorted into five groups: GP (I): control and the other rat groups were induced diabetic by a single dose of streptozocine i.p, at dose of (55 mg/kg/b.w).GP II was considered as diabetic untreated. The other diabetic groups were treated with anserine (1mg/kg b.w, i.p), α-tocopherol (50, 00 IU/kg b.w) or combined. After 12 weeks, fasting serum was subjected for assay of glucose, glycated hemoglobin (HA1c), advanced glycated end products (AGEs), oxidative stress markers (MDA, SOD) and inflammatory markers (TNF-α and IL-6).</p><p><strong>Results: </strong>Data obtained revealed that, diabetic rats treated with anserine or α-tocopherol or combination improve abnormalities, glucose, HA1c, antioxidant enzymes, inflammatory mediators and AGEs versus untreated diabetic.</p><p><strong>Conclusion: </strong>Dietary supplement of natural products as anserine and α-tocopherol protect against micro and microvascular system, which is suggestive as alternative or complementary therapeutic agents for diabetic complications as neuropathy, nephropathy, and CVD.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"395-399"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research progress on the role of ginsenoside Rd in central nervous system diseases. 人参皂苷Rd在中枢神经系统疾病中的作用研究进展。
African health sciences Pub Date : 2024-12-01 DOI: 10.4314/ahs.v24i4.41
Xiaoyu Ma, Juejin Wang
{"title":"Research progress on the role of ginsenoside Rd in central nervous system diseases.","authors":"Xiaoyu Ma, Juejin Wang","doi":"10.4314/ahs.v24i4.41","DOIUrl":"10.4314/ahs.v24i4.41","url":null,"abstract":"<p><p>Ginsenoside Rd (GSRd) is one of the rare saponin monomers extracted from ginseng. Most importantly, GSRd could effectively cross the intact blood-brain barrier (BBB). Studies have shown that it plays an important role in the treatment of neurological diseases such as ischemic stroke (IS), spinal cord injury (SCI), Alzheimer's disease (AD) and Parkinson's disease (PD). The results of these studies are of great significance for the clinical application of GSRd in the treatment in neurological diseases. This article reviewed the protective effects of GSRd in central nervous system diseases and analysed the related mechanism.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"325-331"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for invasive mold infection after COVID-19: case-control study. COVID-19感染后侵袭性霉菌感染的危险因素:病例对照研究
African health sciences Pub Date : 2024-12-01 DOI: 10.4314/ahs.v24i4.10
Esma Eryilmaz-Eren, Hafize Sav, Zuhal Ozer-Simsek, İbrahim Ozcan, Aysin Kilinc-Toker, Azade Kanat, Ali Cetinkaya, Recep Civan Yuksel, Kaniye Aydin, Seda Guzeldag, Ilhami Celik
{"title":"Risk factors for invasive mold infection after COVID-19: case-control study.","authors":"Esma Eryilmaz-Eren, Hafize Sav, Zuhal Ozer-Simsek, İbrahim Ozcan, Aysin Kilinc-Toker, Azade Kanat, Ali Cetinkaya, Recep Civan Yuksel, Kaniye Aydin, Seda Guzeldag, Ilhami Celik","doi":"10.4314/ahs.v24i4.10","DOIUrl":"10.4314/ahs.v24i4.10","url":null,"abstract":"<p><strong>Background: </strong>Invasive mold infections (IMI) have become common in patients with severe COVID-19 pneumonia, which are difficult to diagnose and treat, with a high mortality rate.</p><p><strong>Objective: </strong>The aim of this study was to determine risk factors for invasive mold infections associated with COVID-19.</p><p><strong>Methods: </strong>In this prospective, case-control study, patients treated for severe COVID-19 pneumonia in intensive care units with invasive mold infection were compared with severe COVID-19 pneumonia patients with no secondary infection (bacterial or fungal). Demographics, treatments received and outcomes were compared.</p><p><strong>Results: </strong>Twenty patients were included in the IMI group and 19 patients in the control group. Invasive aspergillosis was observed in 13 patients (65.0%) while mucormycosis was observed in seven patients (35.0%). Demographics and clinical characteristics were similar between IMI and control group (p>0.005). The 28-day mortality was 60.0% in the IMI group and 15.8% in the control group (p=0.005). The use of steroids has been identified as the most important risk factor for developing IMI (90.0% vs. 15.8%, OR: 25.712, p=0.009).</p><p><strong>Conclusion: </strong>Rationale use of steroids, with appropriate indication, dose and duration is important in the treatment of severe COVID-19 pneumonia.</p>","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"24 4","pages":"77-84"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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