Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention最新文献

{"title":"One-shot Federated Learning on Medical Data using Knowledge Distillation with Image Synthesis and Client Model Adaptation.","authors":"Myeongkyun Kang, Philip Chikontwe, Soopil Kim, Kyong Hwan Jin, Ehsan Adeli, Kilian M Pohl, Sang Hyun Park","doi":"10.1007/978-3-031-43895-0_49","DOIUrl":"10.1007/978-3-031-43895-0_49","url":null,"abstract":"<p><p>One-shot federated learning (FL) has emerged as a promising solution in scenarios where multiple communication rounds are not practical. Notably, as feature distributions in medical data are less discriminative than those of natural images, robust global model training with FL is non-trivial and can lead to overfitting. To address this issue, we propose a novel one-shot FL framework leveraging Image Synthesis and Client model Adaptation (FedISCA) with knowledge distillation (KD). To prevent overfitting, we generate diverse synthetic images ranging from random noise to realistic images. This approach (i) alleviates data privacy concerns and (ii) facilitates robust global model training using KD with decentralized client models. To mitigate domain disparity in the early stages of synthesis, we design noise-adapted client models where batch normalization statistics on random noise (synthetic images) are updated to enhance KD. Lastly, the global model is trained with both the original and noise-adapted client models via KD and synthetic images. This process is repeated till global model convergence. Extensive evaluation of this design on five small- and three large-scale medical image classification datasets reveals superior accuracy over prior methods. Code is available at https://github.com/myeongkyunkang/FedISCA.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":"14221 ","pages":"521-531"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10781197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139418907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laplacian-Former: Overcoming the Limitations of Vision Transformers in Local Texture Detection.","authors":"Reza Azad, Amirhossein Kazerouni, Babak Azad, Ehsan Khodapanah Aghdam, Yury Velichko, Ulas Bagci, Dorit Merhof","doi":"10.1007/978-3-031-43898-1_70","DOIUrl":"10.1007/978-3-031-43898-1_70","url":null,"abstract":"<p><p>Vision Transformer (ViT) models have demonstrated a breakthrough in a wide range of computer vision tasks. However, compared to the Convolutional Neural Network (CNN) models, it has been observed that the ViT models struggle to capture high-frequency components of images, which can limit their ability to detect local textures and edge information. As abnormalities in human tissue, such as tumors and lesions, may greatly vary in structure, texture, and shape, high-frequency information such as texture is crucial for effective semantic segmentation tasks. To address this limitation in ViT models, we propose a new technique, Laplacian-Former, that enhances the self-attention map by adaptively re-calibrating the frequency information in a Laplacian pyramid. More specifically, our proposed method utilizes a dual attention mechanism via efficient attention and frequency attention while the efficient attention mechanism reduces the complexity of self-attention to linear while producing the same output, selectively intensifying the contribution of shape and texture features. Furthermore, we introduce a novel efficient enhancement multi-scale bridge that effectively transfers spatial information from the encoder to the decoder while preserving the fundamental features. We demonstrate the efficacy of Laplacian-former on multi-organ and skin lesion segmentation tasks with +1.87% and +0.76% dice scores compared to SOTA approaches, respectively. Our implementation is publically available at GitHub.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":"14222 ","pages":"736-746"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10830169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139652500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochlear Implant Fold Detection in Intra-operative CT Using Weakly Supervised Multi-task Deep Learning.","authors":"Mohammad M R Khan, Yubo Fan, Benoit M Dawant, Jack H Noble","doi":"10.1007/978-3-031-43996-4_24","DOIUrl":"10.1007/978-3-031-43996-4_24","url":null,"abstract":"<p><p>In cochlear implant (CI) procedures, an electrode array is surgically inserted into the cochlea. The electrodes are used to stimulate the auditory nerve and restore hearing sensation for the recipient. If the array folds inside the cochlea during the insertion procedure, it can lead to trauma, damage to the residual hearing, and poor hearing restoration. Intraoperative detection of such a case can allow a surgeon to perform reimplantation. However, this intraoperative detection requires experience and electrophysiological tests sometimes fail to detect an array folding. Due to the low incidence of array folding, we generated a dataset of CT images with folded synthetic electrode arrays with realistic metal artifact. The dataset was used to train a multitask custom 3D-UNet model for array fold detection. We tested the trained model on real post-operative CTs (7 with folded arrays and 200 without). Our model could correctly classify all the fold-over cases while misclassifying only 3 non fold-over cases. Therefore, the model is a promising option for array fold detection.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":"14228 ","pages":"249-259"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10953791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140186822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fast Reconstruction for Deep Learning PET Head Motion Correction.","authors":"Tianyi Zeng, Jiazhen Zhang, Eléonore V Lieffrig, Zhuotong Cai, Fuyao Chen, Chenyu You, Mika Naganawa, Yihuan Lu, John A Onofrey","doi":"10.1007/978-3-031-43999-5_67","DOIUrl":"10.1007/978-3-031-43999-5_67","url":null,"abstract":"<p><p>Head motion correction is an essential component of brain PET imaging, in which even motion of small magnitude can greatly degrade image quality and introduce artifacts. Building upon previous work, we propose a new head motion correction framework taking fast reconstructions as input. The main characteristics of the proposed method are: (i) the adoption of a high-resolution short-frame fast reconstruction workflow; (ii) the development of a novel encoder for PET data representation extraction; and (iii) the implementation of data augmentation techniques. Ablation studies are conducted to assess the individual contributions of each of these design choices. Furthermore, multi-subject studies are conducted on an ¹⁸F-FPEB dataset, and the method performance is qualitatively and quantitatively evaluated by MOLAR reconstruction study and corresponding brain Region of Interest (ROI) Standard Uptake Values (SUV) evaluation. Additionally, we also compared our method with a conventional intensity-based registration method. Our results demonstrate that the proposed method outperforms other methods on all subjects, and can accurately estimate motion for subjects out of the training set. All code is publicly available on GitHub: https://github.com/OnofreyLab/dl-hmc_fast_recon_miccai2023.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":"14229 ","pages":"710-719"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10758999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139089835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Unified Deep-Learning-Based Framework for Cochlear Implant Electrode Array Localization.","authors":"Yubo Fan, Jianing Wang, Yiyuan Zhao, Rui Li, Han Liu, Robert F Labadie, Jack H Noble, Benoit M Dawant","doi":"10.1007/978-3-031-43996-4_36","DOIUrl":"10.1007/978-3-031-43996-4_36","url":null,"abstract":"<p><p>Cochlear implants (CIs) are neuroprosthetics that can provide a sense of sound to people with severe-to-profound hearing loss. A CI contains an electrode array (EA) that is threaded into the cochlea during surgery. Recent studies have shown that hearing outcomes are correlated with EA placement. An image-guided cochlear implant programming technique is based on this correlation and utilizes the EA location with respect to the intracochlear anatomy to help audiologists adjust the CI settings to improve hearing. Automated methods to localize EA in postoperative CT images are of great interest for large-scale studies and for translation into the clinical workflow. In this work, we propose a unified deep-learning-based framework for automated EA localization. It consists of a multi-task network and a series of postprocessing algorithms to localize various types of EAs. The evaluation on a dataset with 27 cadaveric samples shows that its localization error is slightly smaller than the state-of-the-art method. Another evaluation on a large-scale clinical dataset containing 561 cases across two institutions demonstrates a significant improvement in robustness compared to the state-of-the-art method. This suggests that this technique could be integrated into the clinical workflow and provide audiologists with information that facilitates the programming of the implant leading to improved patient care.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":"14228 ","pages":"376-385"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10976972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140338426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DeepSOZ: A Robust Deep Model for Joint Temporal and Spatial Seizure Onset Localization from Multichannel EEG Data.","authors":"Deeksha M Shama, Jiasen Jing, Archana Venkataraman","doi":"10.1007/978-3-031-43993-3_18","DOIUrl":"https://doi.org/10.1007/978-3-031-43993-3_18","url":null,"abstract":"<p><p>We propose a robust deep learning framework to simultaneously detect and localize seizure activity from multichannel scalp EEG. Our model, called DeepSOZ, consists of a transformer encoder to generate global and channel-wise encodings. The global branch is combined with an LSTM for temporal seizure detection. In parallel, we employ attention-weighted multi-instance pooling of channel-wise encodings to predict the seizure onset zone. DeepSOZ is trained in a supervised fashion and generates high-resolution predictions on the order of each second (temporal) and EEG channel (spatial). We validate DeepSOZ via bootstrapped nested cross-validation on a large dataset of 120 patients curated from the Temple University Hospital corpus. As compared to baseline approaches, DeepSOZ provides robust overall performance in our multi-task learning setup. We also evaluate the intra-seizure and intra-patient consistency of DeepSOZ as a first step to establishing its trustworthiness for integration into the clinical workflow for epilepsy.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":"2023 ","pages":"184-194"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11545985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Democratizing Pathological Image Segmentation with Lay Annotators via Molecular-empowered Learning.","authors":"Ruining Deng, Yanwei Li, Peize Li, Jiacheng Wang, Lucas W Remedios, Saydolimkhon Agzamkhodjaev, Zuhayr Asad, Quan Liu, Can Cui, Yaohong Wang, Yihan Wang, Yucheng Tang, Haichun Yang, Yuankai Huo","doi":"10.1007/978-3-031-43987-2_48","DOIUrl":"10.1007/978-3-031-43987-2_48","url":null,"abstract":"<p><p>Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced domain experts (e.g., pathologists). Moreover, such annotation is error-prone when differentiating fine-grained cell types (e.g., podocyte and mesangial cells) via the naked human eye. In this study, we assess the feasibility of democratizing pathological AI deployment by only using lay annotators (annotators without medical domain knowledge). The contribution of this paper is threefold: (1) We proposed a molecular-empowered learning scheme for multi-class cell segmentation using partial labels from lay annotators; (2) The proposed method integrated Giga-pixel level molecular-morphology cross-modality registration, molecular-informed annotation, and molecular-oriented segmentation model, so as to achieve significantly superior performance via 3 lay annotators as compared with 2 experienced pathologists; (3) A deep corrective learning (learning with imperfect label) method is proposed to further improve the segmentation performance using partially annotated noisy data. From the experimental results, our learning method achieved F1 = 0.8496 using molecular-informed annotations from lay annotators, which is better than conventional morphology-based annotations (F1 = 0.7015) from experienced pathologists. Our method democratizes the development of a pathological segmentation deep model to the lay annotator level, which consequently scales up the learning process similar to a non-medical computer vision task. The official implementation and cell annotations are publicly available at https://github.com/hrlblab/MolecularEL.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":"14225 ","pages":"497-507"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10961594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140290108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physics-Informed Neural Networks for Tissue Elasticity Reconstruction in Magnetic Resonance Elastography.","authors":"Matthew Ragoza, Kayhan Batmanghelich","doi":"10.1007/978-3-031-43999-5_32","DOIUrl":"10.1007/978-3-031-43999-5_32","url":null,"abstract":"<p><p>Magnetic resonance elastography (MRE) is a medical imaging modality that non-invasively quantifies tissue stiffness (elasticity) and is commonly used for diagnosing liver fibrosis. Constructing an elasticity map of tissue requires solving an inverse problem involving a partial differential equation (PDE). Current numerical techniques to solve the inverse problem are noise-sensitive and require explicit specification of physical relationships. In this work, we apply physics-informed neural networks to solve the inverse problem of tissue elasticity reconstruction. Our method does not rely on numerical differentiation and can be extended to learn relevant correlations from anatomical images while respecting physical constraints. We evaluate our approach on simulated data and <i>in vivo</i> data from a cohort of patients with non-alcoholic fatty liver disease (NAFLD). Compared to numerical baselines, our method is more robust to noise and more accurate on realistic data, and its performance is further enhanced by incorporating anatomical information.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":"14229 ","pages":"333-343"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11141115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shape-Aware 3D Small Vessel Segmentation with Local Contrast Guided Attention.","authors":"Zhiwei Deng, Songnan Xu, Jianwei Zhang, Jiong Zhang, Danny J Wang, Lirong Yan, Yonggang Shi","doi":"10.1007/978-3-031-43901-8_34","DOIUrl":"10.1007/978-3-031-43901-8_34","url":null,"abstract":"<p><p>The automated segmentation and analysis of small vessels from <i>in vivo</i> imaging data is an important task for many clinical applications. While current filtering and learning methods have achieved good performance on the segmentation of large vessels, they are sub-optimal for small vessel detection due to their apparent geometric irregularity and weak contrast given the relatively limited resolution of existing imaging techniques. In addition, for supervised learning approaches, the acquisition of accurate pixel-wise annotations in these small vascular regions heavily relies on skilled experts. In this work, we propose a novel self-supervised network to tackle these challenges and improve the detection of small vessels from 3D imaging data. First, our network maximizes a novel shape-aware flux-based measure to enhance the estimation of small vasculature with non-circular and irregular appearances. Then, we develop novel local contrast guided attention(LCA) and enhancement(LCE) modules to boost the vesselness responses of vascular regions of low contrast. In our experiments, we compare with four filtering-based methods and a state-of-the-art self-supervised deep learning method in multiple 3D datasets to demonstrate that our method achieves significant improvement in all datasets. Further analysis and ablation studies have also been performed to assess the contributions of various modules to the improved performance in 3D small vessel segmentation. Our code is available at https://github.com/dengchihwei/LCNetVesselSeg.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":"14223 ","pages":"354-363"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10948105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relaxation-Diffusion Spectrum Imaging for Probing Tissue Microarchitecture.","authors":"Ye Wu, Xiaoming Liu, Xinyuan Zhang, Khoi Minh Huynh, Sahar Ahmad, Pew-Thian Yap","doi":"10.1007/978-3-031-43993-3_15","DOIUrl":"10.1007/978-3-031-43993-3_15","url":null,"abstract":"<p><p>Brain tissue microarchitecture is characterized by heterogeneous degrees of diffusivity and rates of transverse relaxation. Unlike standard diffusion MRI with a single echo time (TE), which provides information primarily on diffusivity, relaxation-diffusion MRI involves multiple TEs and multiple diffusion-weighting strengths for probing tissue-specific coupling between relaxation and diffusivity. Here, we introduce a relaxation-diffusion model that characterizes tissue apparent relaxation coefficients for a spectrum of diffusion length scales and at the same time factors out the effects of intra-voxel orientation heterogeneity. We examined the model with an in vivo dataset, acquired using a clinical scanner, involving different health conditions. Experimental results indicate that our model caters to heterogeneous tissue microstructure and can distinguish fiber bundles with similar diffusivities but different relaxation rates. Code with sample data is available at https://github.com/dryewu/RDSI.</p>","PeriodicalId":94280,"journal":{"name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","volume":"14227 ","pages":"152-162"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11340880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}