Revista da Associacao Medica Brasileira (1992)最新文献

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Are smartphones a tool to cope with the fear of childbirth? The correlation between the fear of loss of connection and the fear of childbirth. 智能手机是应对分娩恐惧的工具吗?失去联系的恐惧与分娩恐惧之间的相关性。
Revista da Associacao Medica Brasileira (1992) Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.1590/1806-9282.20240550
Fadime Bayri Bingol, Arzu Aydoğan, Zeynep Dilşah Karaçam, Derya Çayiroğlu, Büşra Karanfil, Hatice Nur Kaya
{"title":"Are smartphones a tool to cope with the fear of childbirth? The correlation between the fear of loss of connection and the fear of childbirth.","authors":"Fadime Bayri Bingol, Arzu Aydoğan, Zeynep Dilşah Karaçam, Derya Çayiroğlu, Büşra Karanfil, Hatice Nur Kaya","doi":"10.1590/1806-9282.20240550","DOIUrl":"10.1590/1806-9282.20240550","url":null,"abstract":"<p><strong>Objective: </strong>With the spread of smartphones, they have become an indispensable part of life, and nomophobia (No-Mobile-Phone Phobia) has emerged.</p><p><strong>Methods: </strong>The present research is a cross-sectional study and was conducted with 3,870 primiparous pregnant women between April and May 2022. The research data were collected using the Personal Information Form, Nomophobia Questionnaire, and Wijma Delivery Expectancy/Experience Questionnaire.</p><p><strong>Results: </strong>The Wijma Delivery Expectancy/Experience Questionnaire score of the pregnant women who participated in the study was 22.3% (n=863) had a clinical fear of childbirth and 19.5% (n=753) had extreme nomophobia. Considering the correlation of the Nomophobia Questionnaire and Wijma Delivery Expectancy/Experience Questionnaire scores with other variables, it was found that the Wijma Delivery Expectancy/Experience Questionnaire scores increased with the increasing Nomophobia Questionnaire total score (p=0.000, r=236) and the Nomophobia Questionnaire total score and fear of childbirth increased with an increase in the daily phone usage time. It was also revealed that women who had smartphone applications related to fetal development had higher nomophobia levels (p=0.0001), while they had a lower fear of childbirth.</p><p><strong>Conclusion: </strong>This study found that one in every five pregnant women was extremely nomophobic and had a clinical fear of childbirth and that nomophobia and the fear of childbirth were correlated at the clinical level. In this regard, women should prefer face-to-face communication rather than smartphones throughout the pregnancy period.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371127/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coenzyme q10 may attenuate cyclophosphamide-induced renal damage. 辅酶q10可减轻环磷酰胺引起的肾损伤。
Revista da Associacao Medica Brasileira (1992) Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.1590/1806-9282.20240772
Daoyun Lei
{"title":"Coenzyme q10 may attenuate cyclophosphamide-induced renal damage.","authors":"Daoyun Lei","doi":"10.1590/1806-9282.20240772","DOIUrl":"10.1590/1806-9282.20240772","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of two labor induction regimens with intravaginal misoprostol 25 μg and adverse perinatal outcomes. 阴道内米索前列醇 25 μg 两种引产方案与围产期不良结局的比较。
Revista da Associacao Medica Brasileira (1992) Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.1590/1806-9282.20240286
Marcela Beraldo Santiago, Talita Beraldo Santiago, Samuel Machado Oliveira, João Victor Jacomele Caldas, Edward Araujo Júnior, Alberto Borges Peixoto
{"title":"Comparison of two labor induction regimens with intravaginal misoprostol 25 μg and adverse perinatal outcomes.","authors":"Marcela Beraldo Santiago, Talita Beraldo Santiago, Samuel Machado Oliveira, João Victor Jacomele Caldas, Edward Araujo Júnior, Alberto Borges Peixoto","doi":"10.1590/1806-9282.20240286","DOIUrl":"10.1590/1806-9282.20240286","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to compare two labor induction regimens (4 and 6 h), to determine predictors of successful labor induction with intravaginal misoprostol 25 μg tablets, and to evaluate the association with adverse perinatal outcomes.</p><p><strong>Methods: </strong>This was a retrospective cohort study that included singleton pregnancies undergoing induction of labor with an intravaginal misoprostol 25 μg tablet between 37 and 42 weeks of gestation. The pregnant women were divided into two groups: Group 1-intravaginal misoprostol 25 μg every 4 h and Group 2-intravaginal misoprostol 25 μg every 6 h.</p><p><strong>Results: </strong>Pregnant women were divided into Group 1 (n=289) and Group 2 (n=278). Group 1 had a higher median number of intravaginal misoprostol 25 μg tablets (3.0 vs. 2.0 tablets, p<0.001), a lower prevalence of postpartum hemorrhage (7.6 vs. 32.7%, p<0.001), and a higher need for oxytocin (odds ratio [OR]: 2.1, 95%CI: 1.47-2.98, p<0.001) than Group 2. Models including intravaginal misoprostol 25 μg tablets every 4 and 6 h [x2(1)=23.7, OR: 4.35, p<0.0001], parity [x2(3)=39.4, OR: 0.59, p=0.031], and Bishop's score [x2(4)=10.8, OR: 0.77, p=0.019] were the best predictors of failure of labor induction. A statistically significant difference between groups was observed between the use of the first intravaginal misoprostol 25 μg tablet at the beginning (Breslow p<0.001) and the end of the active labor phase (Long Hank p=0.002).</p><p><strong>Conclusion: </strong>Pregnant women who used intravaginal misoprostol 25 μg every 4 h had a longer time from the labor induction to the beginning of the active phase of labor and higher rates of adverse perinatal outcomes than women who used intravaginal misoprostol 25 μg every 6 h.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
(In)Fertility in the Down syndrome. (唐氏综合症患者的生育能力。
Revista da Associacao Medica Brasileira (1992) Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.1590/1806-9282.20240537
Alessandra Bernadete Trovó de Marqui, Maria de Fátima Borges
{"title":"(In)Fertility in the Down syndrome.","authors":"Alessandra Bernadete Trovó de Marqui, Maria de Fátima Borges","doi":"10.1590/1806-9282.20240537","DOIUrl":"10.1590/1806-9282.20240537","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of cognitive function in elderly patients with heart failure. 评估老年心力衰竭患者的认知功能。
Revista da Associacao Medica Brasileira (1992) Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.1590/1806-9282.20240429
Leandro Marques da Silva, Carla Priscilla Belchior Marques Sampaio, Nair Eloá Dos Santos Guimarães, Luiza Pinto Moreno, Gedean Souza Pontes, Emmanuela de Jesus Furtado Ferreira, José Albuquerque de Figueiredo Neto
{"title":"Assessment of cognitive function in elderly patients with heart failure.","authors":"Leandro Marques da Silva, Carla Priscilla Belchior Marques Sampaio, Nair Eloá Dos Santos Guimarães, Luiza Pinto Moreno, Gedean Souza Pontes, Emmanuela de Jesus Furtado Ferreira, José Albuquerque de Figueiredo Neto","doi":"10.1590/1806-9282.20240429","DOIUrl":"10.1590/1806-9282.20240429","url":null,"abstract":"<p><strong>Objective: </strong>To compare the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) tests for the identification of cognitive deficit (CD) in elderly patients with heart failure (HF).</p><p><strong>Methods: </strong>This was a cross-sectional study with an observational design involving 43 elderly patients with HF of both sexes, treated by the Unified Health System, who were able to understand and follow the study instructions. A sociodemographic and clinical questionnaire and the MMSE and MoCA neurocognitive tests were applied.</p><p><strong>Results: </strong>The mean age of the patients was 67 years; 67.44% were male; 53.49% were white; 58.14% had 1-4 years of schooling; 58.14% had an income of half to one minimum wage; 55.81% were married; 53.49% had a family history of HF; 90.7% denied smoking; 83.72% denied alcohol intake; 65.12% did not practice physical activity; 83.72% were hypertensive; 30.23% were diabetic; 57.89% had LVEF ≥ 50%; 39.53% have NYHA II; and 88.37% did not have a pacemaker. In the identification of CD, the MMSE test detected it in 25.58% of the patients, while the MoCA test identified it in 23.26% (p=0.043).</p><p><strong>Conclusion: </strong>It was concluded that the MMSE test performed better than the MoCA test in the identification of CD in elderly patients with HF.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of kinesiology taping on balance, gait, and gross motor function in the lower limbs of children with cerebral palsy: a systematic review. 运动绑带对脑瘫儿童下肢平衡、步态和粗大运动功能的效果:系统性综述。
Revista da Associacao Medica Brasileira (1992) Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.1590/1806-9282.20240300
Seth Kwame Agyenkwa, Duaa Abualkhair, Rustem Mustafaoglu, Ahmet Abo Orabi
{"title":"The effectiveness of kinesiology taping on balance, gait, and gross motor function in the lower limbs of children with cerebral palsy: a systematic review.","authors":"Seth Kwame Agyenkwa, Duaa Abualkhair, Rustem Mustafaoglu, Ahmet Abo Orabi","doi":"10.1590/1806-9282.20240300","DOIUrl":"10.1590/1806-9282.20240300","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between women's personality traits and fear of childbirth, birth satisfaction, and postpartum depression. 妇女的个性特征与分娩恐惧、分娩满意度和产后抑郁之间的关系。
Revista da Associacao Medica Brasileira (1992) Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.1590/1806-9282.20231730
Feyza Aktaş Reyhan, Elif Dağlı
{"title":"The relationship between women's personality traits and fear of childbirth, birth satisfaction, and postpartum depression.","authors":"Feyza Aktaş Reyhan, Elif Dağlı","doi":"10.1590/1806-9282.20231730","DOIUrl":"10.1590/1806-9282.20231730","url":null,"abstract":"<p><strong>Objective: </strong>This study was conducted to determine the relationship between women's personality traits and their fear of childbirth, birth satisfaction, and postpartum depression.</p><p><strong>Methods: </strong>This cross-sectional study was conducted between April and August 2022 among healthy third-trimester pregnant women aged 18-49 years who applied to the obstetrics and gynecology outpatient clinic of a state hospital. Data were collected by the researchers by face-to-face interview method in three stages. Participants were administered the Personal Information Form, the Five-Factor Personality Scale, and the Birth Anticipation/Experience Scale at the first interview; the Birth Satisfaction Scale on the 10th day after normal birth; and the Edinburg Postpartum Depression Scale 4 weeks after birth.</p><p><strong>Results: </strong>There was a significant positive correlation between neurotic personality traits and fear of childbirth and postpartum depression, while there was a negative correlation with other personality traits (p<0.001). There was no significant relationship between birth satisfaction and personality traits (p>0.05). The effect of personality traits on fear of childbirth and postpartum depression was analyzed by multiple linear regression analysis. The regression model tested for the effect of personality traits on fear of childbirth and postpartum depression was found significant (p<0.001). According to the model, 26% of the variability in fear of childbirth and 9.1% of the variability in postpartum depression were explained by personality traits.</p><p><strong>Conclusion: </strong>This study showed that neuroticism, which is one of the personality traits of women, had a positive effect on fear of childbirth and postpartum depression. No significant relationship was found between birth satisfaction and personality traits.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A study on obese patients' participation in cancer screening programs: an example from Turkey. 关于肥胖患者参与癌症筛查计划的研究:以土耳其为例。
Revista da Associacao Medica Brasileira (1992) Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.1590/1806-9282.20240261
Sezgin Türkoğlu, Mehmet Özen, Remziye Nur Eke, Aysima Bulca Acar
{"title":"A study on obese patients' participation in cancer screening programs: an example from Turkey.","authors":"Sezgin Türkoğlu, Mehmet Özen, Remziye Nur Eke, Aysima Bulca Acar","doi":"10.1590/1806-9282.20240261","DOIUrl":"10.1590/1806-9282.20240261","url":null,"abstract":"<p><strong>Objective: </strong>Obesity is associated with many types of cancers. Despite this, the participation of obese individuals in cancer screenings is limited. The aim of this study was to evaluate the cancer screening-related attitudes of obese patients.</p><p><strong>Methods: </strong>The study included 185 obese patients who presented to the obesity center (OC) and 191 obese patients who presented to the family medicine outpatient clinic from October to December 2019. The participants in both groups were first asked whether or not they had ever undergone any cancer screening tests and then provided with relevant training. After 3 months, the participants were contacted again and their attitudes toward cancer screening tests were re-evaluated.</p><p><strong>Results: </strong>Patients who followed in the OC were found to have higher awareness of and compliance with cancer screening tests than the obese patients admitted to the outpatient clinic. The factors of being female, being followed in the OC, and residing in an urban area were positively associated with participation in cancer screening tests.</p><p><strong>Conclusion: </strong>Monitoring obese patients in target-oriented facilities such as an OC increases the chance of success in the fight against obesity and related health problems.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Female genital mutilation and urinary incontinence: an analytical comparison with Sudan's prevalent demography. 切割女性生殖器与尿失禁:与苏丹人口流行情况的分析比较。
Revista da Associacao Medica Brasileira (1992) Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.1590/1806-9282.20231663
Mustafa Cengiz Dura, Hilal Aktürk, Salih Mahmoud Abaker Salih, Özgür Aslan, Metehan Hergüner, Murat Ekin
{"title":"Female genital mutilation and urinary incontinence: an analytical comparison with Sudan's prevalent demography.","authors":"Mustafa Cengiz Dura, Hilal Aktürk, Salih Mahmoud Abaker Salih, Özgür Aslan, Metehan Hergüner, Murat Ekin","doi":"10.1590/1806-9282.20231663","DOIUrl":"10.1590/1806-9282.20231663","url":null,"abstract":"<p><strong>Objective: </strong>Female genital mutilation/cutting impacts over 200 million women globally and is linked to obstetric complications as well as long-term urogynecological and psychosexual issues that are frequently overlooked and inadequately addressed. This study aimed to assess the impact of female genital mutilation/cutting on urinary incontinence.</p><p><strong>Methods: </strong>This cross-sectional study was conducted in the gynecology department of the Research Hospital located in the Nyala rural region of Sudan. The participants were interviewed to gather socio-demographic and background information. In addition, they received a thorough gynecological examination to evaluate the presence and type of female genital mutilation/cutting. The Incontinence Impact Questionnaire and the Urogenital Distress Inventory were applied to the group with female genital mutilation/cutting and the control group without female genital mutilation/cutting to evaluate urinary incontinence and related discomfort. Subsequently, the scores of both participant groups were compared.</p><p><strong>Results: </strong>The study compared age, weight, height, BMI, gravida, parity, and sexual intercourse averages between groups. The mean Urogenital Distress Inventory-6 and Incontinence Impact Questionnaire-7 scores of individuals who underwent mutilation were higher than those of individuals who did not undergo mutilation (p<0.001). Notably, participants subjected to infibulation exhibited significantly higher average scores on both measures in contrast with the other groups (p<0.001).</p><p><strong>Conclusion: </strong>A higher proportion of mutilated participants, specifically those with infibulation, are afflicted with symptoms of incontinence.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of ultrasound and mitofusin-2 levels to predict pregnancy outcomes in patients with severe preeclampsia: a case-control study. 超声波和丝裂霉素-2 水平在预测重度子痫前期患者妊娠结局中的作用:一项病例对照研究。
Revista da Associacao Medica Brasileira (1992) Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.1590/1806-9282.20240152
Kazım Uçkan, Çağdaş Özgökçe, Yusuf Başkiran, Ömer Gökhan Eyisoy, İzzet Çeleğen, Halil İbrahim Akbay
{"title":"The role of ultrasound and mitofusin-2 levels to predict pregnancy outcomes in patients with severe preeclampsia: a case-control study.","authors":"Kazım Uçkan, Çağdaş Özgökçe, Yusuf Başkiran, Ömer Gökhan Eyisoy, İzzet Çeleğen, Halil İbrahim Akbay","doi":"10.1590/1806-9282.20240152","DOIUrl":"10.1590/1806-9282.20240152","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate mitofusin-2 levels and fetal Doppler ultrasonography effects in patients with severe preeclampsia.</p><p><strong>Methods: </strong>This single-center case-control study was conducted in the gynecology service of the university hospital in Van. A total of 90 pregnant women aged 18-40 years were included in the study. Of these, 30 are normal, 30 have mild preeclampsia, and 30 are pregnant with severe preeclampsia. In this study, especially in severe preeclampsia patients, serum mitofusin-2 levels and important fetal Doppler flows such as uterine arterial pressure, umbilical arterial pressure, and 1st and 5th minute Apgar scores, birth weight, and the relationship between postnatal outcomes such as week of birth and the number of patients in the neonatal intensive care unit were investigated.</p><p><strong>Results: </strong>There was a significant difference between the three groups in terms of mitofusin-2 levels, which was the highest in the group (p<0.05). Maternal serum mitofusin-2 levels were positively correlated with uterine arterial pressure (r=0.543, p=0.007), umbilical arterial pressure (r=0.238, p=0.008), diastolic blood pressure, and systolic blood pressure (p<0.001). Receiver operating characteristic curve of mitofusin-2 in predicting preeclampsia is as follows: optimal cutoff 1.6 ng/mL; area under the curve: 0.861; 95%CI: 0.786-0.917; sensitivity: 83.9%; and specificity: 70.0%, (p≤0.001). A one-unit increase in mitofusin-2 resulted in a statistically significant 4.21-fold increase in preeclampsia risk.</p><p><strong>Conclusion: </strong>This study recommends the use of mitofusin-2 together with fetal Doppler ultrasound findings as a reliable indicator of preeclampsia severity.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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