Revista da Associacao Medica Brasileira (1992)最新文献

{"title":"Comparison of ultrasound- and computed tomography-guided pulsed radiofrequency in treating ophthalmic branch postherpetic neuralgia: a retrospective study.","authors":"Qianqian Shen, Bo Wang, Jianmin Yu, Jurong Xia","doi":"10.1590/1806-9282.20241004","DOIUrl":"10.1590/1806-9282.20241004","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to compare the efficacy and safety between ultrasound- and computed tomography-guided pulsed radiofrequency in treating ophthalmic branch postherpetic neuralgia.</p><p><strong>Methods: </strong>A retrospective study was conducted on data of 84 patients with ophthalmic branch postherpetic neuralgia. According to the puncture guiding method, the patients were divided into the ultrasound- and computed tomography-guided groups, which received the ultrasound- and computed tomography-guided supraorbital nerve pulsed radiofrequency treatment, respectively. The puncture time, numeric rating scale pain score before pulsed radiofrequency and after pulsed radiofrequency, effective rate of treatment, and intraoperative and postoperative adverse events were observed.</p><p><strong>Results: </strong>The puncture time in the ultrasound-guided group was significantly shorter than that in the computed tomography-guided group (p<0.05). At 1, 4, and 12 weeks after pulsed radiofrequency, in two groups, the numeric rating scale pain score was significantly lower than that before pulsed radiofrequency, respectively (p<0.05). At each time, the numeric rating scale pain score showed no significant difference between the two groups (p>0.05). At 12 weeks after pulsed radiofrequency, there was no significant difference in the effective rate of treatment between the two groups (p>0.05). During the intraoperative and postoperative periods, the incidences of adverse event hematoma and oculocardiac reflex in the ultrasound-guided group were significantly lower than those in the computed tomography-guided group, respectively (p<0.05).</p><p><strong>Conclusions: </strong>Both ultrasound- and computed tomography-guided supraorbital nerve pulsed radiofrequencys have good efficacy in treating the ophthalmic branch postherpetic neuralgia. Compared with the computed tomography-guided pulsed radiofrequency, the ultrasound-guided pulsed radiofrequency has faster puncture operation and is safer. It is more worthy of clinical applications.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 11","pages":"e20241004"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of antioxidants on antioxidant capacity, DNA fragmentation, and chromatin quality in subfertile men: a randomized clinical trial study.","authors":"Mesut Sengul, Neslihan Hekim, Ramazan Asci, Sezgin Gunes","doi":"10.1590/1806-9282.20240211","DOIUrl":"10.1590/1806-9282.20240211","url":null,"abstract":"<p><strong>Objective: </strong>This randomized clinical trial study aims to investigate the effects of antioxidant food supplementation on the total antioxidant capacity of seminal plasma, sperm DNA fragmentation, sperm chromatin quality, and semen parameters.</p><p><strong>Methods: </strong>In this study, a total of 48 subfertile men with moderate physical activity were included. Group 1 was recommended to use the antioxidant supplements, while antioxidant food supplements were not given to Group 2. Total antioxidant capacity, sperm DNA fragmentation, sperm chromatin structure, hormone levels, physical activities, and semen parameters were evaluated before and after treatment. Total antioxidant capacity, sperm DNA fragmentation, and sperm chromatin structure were assessed using ELISA, transferase dUTP nick end labeling, and aniline blue staining, respectively.</p><p><strong>Results: </strong>Sperm DNA fragmentation (p=0.003) and histone/protamine ratio (p<0.001) were significantly decreased in the patients receiving antioxidant treatment. There was no statistical difference in the total antioxidant capacity values of the post-treatment groups.</p><p><strong>Conclusion: </strong>Antioxidant therapy seems to improve sperm DNA fragmentation and histone/protamine ratios in subfertile patients.</p><p><strong>Clinical trial registration number: </strong>NCT06042738.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240211"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leadership has been happening.","authors":"Luís Santos Pinheiro","doi":"10.1590/1806-9282.20241245","DOIUrl":"10.1590/1806-9282.20241245","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20241245"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alkalized lidocaine in endotracheal tube cuff inflation in patients undergoing thyroidectomy surgery: a clinical trial.","authors":"Gaudencio Barbosa Junior, Geraldo José Coelho Granja Filho, Caio Marcio Barros de Oliveira, Plínio da Cunha Leal, Marcelo Souza de Andrade, Ed Carlos Rey Moura","doi":"10.1590/1806-9282.20240740","DOIUrl":"10.1590/1806-9282.20240740","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to compare the postoperative effects of endotracheal tube cuff inflation with alkalized lidocaine in patients undergoing thyroidectomy surgery.</p><p><strong>Methods: </strong>This is a randomized, double-blind clinical trial between August 2020 and August 2022 at the Hospital São Domingos, São Luís, Maranhão, Brazil. Patients over 18 years who underwent thyroidectomy of both sexes, American Society of Anesthesiologists (ASA) I or ASA II, were included. Patients with difficult orotracheal intubation, smoking, cuff rupture during orotracheal intubation, heart, lung, or neuropathies, previous surgery of the larynx or trachea, with risk of aspiration of gastric contents, or with the need to use a nasogastric tube were excluded. Patients were randomly selected and divided into the control group, whose cuff was filled with 0.9% saline solution, and the alkalinized lidocaine group, where the cuff was filled with 2% lidocaine and 8.4% sodium bicarbonate.</p><p><strong>Results: </strong>The control group had higher systolic blood pressure [137 (94-183) mmHg] medians after extubation than the alkalinized lidocaine group [127 (82-189) mmHg] (p=0.03). The same was observed in heart rate values [control group: 86 (62-120); alkalinized lidocaine group: 80 (53-120)] (p=0.034). The alkalinized lidocaine group showed a significant increase in the ability to sustain phonation in the 24 h postoperatively, from 82.0 to 98.0% (p=0.031).</p><p><strong>Conclusion: </strong>There was no protective effect of the use of alkalinized lidocaine on the sensation of swallowing and complaints after thyroidectomy surgery. There was a significant improvement in hemodynamic response in the intervention group after extubation.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240740"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1590/1806-9282.20240801ERRATUM","DOIUrl":"10.1590/1806-9282.20240801ERRATUM","url":null,"abstract":"<p><p>[This corrects the article doi: 10.1590/1806-9282.20240801].</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240801ERRATUM"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary patterns and inflammatory cytokine levels in healthy adult and adolescent women, whether pregnant or not: a prospective cohort study.","authors":"Vanessa Migray Moreto, Cristina Aparecida Falbo Guazzelli, Erika Ono, Karen Priscilla Tezotto Pendeloski, Edward Araujo Júnior, Silvia Daher","doi":"10.1590/1806-9282.20240538","DOIUrl":"10.1590/1806-9282.20240538","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to assess the dietary pattern of healthy adult and adolescent women, pregnant and non-pregnant, and relate this profile to clinical and laboratory characteristics.</p><p><strong>Methods: </strong>A prospective cohort study was carried out with 40 women who met the selection criteria: 10 non-pregnant adults, 10 pregnant adults, 10 non-pregnant adolescents, and 10 pregnant adolescents. Dietary data were collected using a registration form, a 24-h recall, and a food frequency questionnaire. Serum levels of interleukin 6 and tumor necrosis factor α were determined by capture ELISA.</p><p><strong>Results: </strong>The majority of women were married (22.5%), had completed high school (57.5%), and were white (47.5%). Overall, only one (10%) pregnant adult reported smoking. Dietary supplement use was reported by eight (80%) pregnant adults, four (40%) pregnant adolescents, two (20%) non-pregnant adolescents, and no non-pregnant adults. Pregnant adolescents had a higher intake of omega-3 when compared to pregnant adults and non-pregnant adults (p=0.01 and 0.02, respectively). Pregnant adolescents consumed less minimally processed foods than pregnant adults, non-pregnant adults, and non-pregnant adolescents (p=0.008, 0.019, and 0.024, respectively). Serum levels of tumor necrosis factor α and interleukin 6 did not show statistical differences among the four groups (p=0.229 and 0.440, respectively).</p><p><strong>Conclusions: </strong>The dietary patterns of healthy adult and adolescent women, whether pregnant or not, were similar, with pregnant adolescents having a higher intake of omega-3. Pregnant adolescents ate less in natura (minimally processed) food than all the other women.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 11","pages":"e20240538"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lack of association between the -2549 insertion/deletion variant of vascular endothelial growth factor and coronary artery disease in the Turkish population.","authors":"Serbulent Yigit, Ayse Feyda Nursal, Atac Celik, Recai Aci, Elgiz Askeroglu","doi":"10.1590/1806-9282.20240333","DOIUrl":"10.1590/1806-9282.20240333","url":null,"abstract":"<p><strong>Objective: </strong>Coronary artery disease is the leading cause of death worldwide. Vascular endothelial growth factor is known to induce endothelial cell migration and proliferation, increase vascular permeability, and modulate thrombogenicity. The aim of this study is to investigate the relationship between the VEGF insertion/deletion (I/D) variant (rs35569394) and coronary artery disease susceptibility in the Turkish population.</p><p><strong>Methods: </strong>A total of 206 subjects, including 106 coronary artery disease patients and 100 controls, were included in this study. The VEGF I/D variant was genotyped using the polymerase chain reaction method.</p><p><strong>Results: </strong>The frequency of the I/I, I/D, and D/D genotypes was 35.84 versus 37%, 33.97 versus 36%, and 30.19 versus 27% in patients and the control group, respectively. VEGF I/D genotype and allele distribution were not statistically significant between coronary artery disease patients and controls (p>0.05). There was no significant difference between VEGF I/D genotype distribution and patient characteristics including age, gender, disease duration, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride, history of hypertension, history of diabetes mellitus, and smoking (p>0.05).</p><p><strong>Conclusion: </strong>This study suggests that the VEGF I/D variant is not a predisposing factor to coronary artery disease disease in a Turkish sample.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240333"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Serum and urinary angiotensinogen levels as prognostic indicators in acute kidney injury: a prospective study\".","authors":"Cheng Chen, Jiangtao Zhu","doi":"10.1590/1806-9282.20240971","DOIUrl":"10.1590/1806-9282.20240971","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240971"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between vascular endothelial growth factor, soluble urokinase plasminogen activator receptor, and tricuspid annular plane systolic excursion/systolic pulmonary artery pressure ratio in group E chronic obstructive lung disease.","authors":"Sami Deniz, Burcu Uludağ, Ferhat Demirci","doi":"10.1590/1806-9282.20240589","DOIUrl":"10.1590/1806-9282.20240589","url":null,"abstract":"<p><strong>Objective: </strong>Vascular endothelial growth factor is a signaling protein created by cells performing important bodily functions. Vascular endothelial growth factor is abundant in the lung, and plasma levels are elevated in patients with severe pulmonary arterial hypertension. An association between soluble urokinase plasminogen activator receptor, an inflammatory biomarker, and soluble urokinase plasminogen activator receptor levels and interstitial pulmonary and vascular involvement (e.g., development of pulmonary hypertension) has been shown in SSc patients. The tricuspid annular plane systolic excursion/systolic pulmonary artery pressure ratio, which has been recommended as a useful diagnostic tool in the last guideline, is one of the additional echocardiographic signs suggestive of pulmonary hypertension. We aimed to examine whether these biomarkers contribute to the diagnosis and management of pulmonary hypertension.</p><p><strong>Methods: </strong>Patients with group E chronic obstructive lung disease were included in this prospective study. Demographic data, echocardiographic signs about the right ventricle (right atrium area, tricuspid annular plane systolic excursion/systolic pulmonary artery pressure, fractional area change, and right ventricular outflow tract), and peripheral blood analysis were examined and recorded.</p><p><strong>Results: </strong>A total of 70 patients, 12 of whom were female, were analyzed in the study. The mean age was 66.6±8.7 years. The mean vascular endothelial growth factor-A and soluble urokinase plasminogen activator receptor were 91.05±70.7 and 955.8±571.1, and their Pearson correlation coefficients between vascular endothelial growth factor-A and tricuspid annular plane systolic excursion/systolic pulmonary artery pressure, and soluble urokinase plasminogen activator receptor and tricuspid annular plane systolic excursion/systolic pulmonary artery pressure ratio were 0.341 (p=0.004) and -0.045 (p=0.70), respectively. The linear regression model included four variables with significant correlation (vascular endothelial growth factor-A, right atrium area, fractional area change, and right ventricular outflow tract). Three steps were performed, and adjusted r2 was 0.22, 0.22, 0.20, and p<0.001 for each step. Vascular endothelial growth factor-A and right ventricular outflow tract remained in the last step. It was detected a standardized coefficient beta of 0.322 (p=0.004) and a 95%CI 0.000-0.001 for vascular endothelial growth factor-A.</p><p><strong>Conclusion: </strong>Vascular endothelial growth factor-A is correlated with the tricuspid annular plane systolic excursion/systolic pulmonary artery pressure ratio and not with soluble urokinase plasminogen activator receptor.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240589"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does hyperprolactinemia treatment affect pregnancy and perinatal outcomes?","authors":"Amanda Carvalho Santos, Daniela Angerame Yela, Renan Massao Nakamura, Beatriz Cipriano Ribas, Pedro Henrique Rosa E Silva, Bianaca Mota, Cristina Laguna Benetti-Pinto","doi":"10.1590/1806-9282.20240634","DOIUrl":"10.1590/1806-9282.20240634","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to assess obstetric and perinatal outcomes in women with hyperprolactinemia according to the type of treatment indicated, with cabergoline or bromocriptine.</p><p><strong>Methods: </strong>A retrospective cohort study with 464 women diagnosed with hyperprolactinemia was undertaken at the endocrine gynecology outpatient clinic of a tertiary hospital from May 2002 to February 2022. All women diagnosed with hyperprolactinemia who were being treated with dopamine agonists (cabergoline or bromocriptine) and who became pregnant during the follow-up were included. Women whose medical records did not provide data related to pregnancy and delivery were excluded. The women were divided into two groups according to the type of treatment: bromocriptine or cabergoline. Clinical and laboratory characteristics and obstetric and perinatal outcomes, such as complications during pregnancy, type of delivery, and intrapartum complications, were evaluated in both groups.</p><p><strong>Results: </strong>Of the 464 women evaluated, 72 became pregnant during the follow-up, 66 of them were using dopamine agonists, while 6 were not using medication. The mean age of the women was 28.3±6.8 years. Among the causes of hyperprolactinemia, 48.6% were idiopathic, 45.7% were tumoral, and 3.7% had other causes. Most women with idiopathic hyperprolactinemia used bromocriptine, while those with tumoral hyperprolactinemia used cabergoline (p=0.04). There was no difference in obstetric outcomes according to the type of treatment used. The majority of women did not have any complications during pregnancy (76.3%) or intrapartum (86.8%).</p><p><strong>Conclusion: </strong>Regardless of the type of previous drug treatment with dopamine agonists, hyperprolactinemia does not alter obstetric outcomes.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240634"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}