Revista da Associacao Medica Brasileira (1992)最新文献

{"title":"Comments on \"The role of serum adropin in determining the clinical outcomes of patients with traumatic brain injury: a case-control study\".","authors":"Şebnem Zeynep Eke Kurt","doi":"10.1590/1806-9282.20240999","DOIUrl":"10.1590/1806-9282.20240999","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240999"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative surgical margin results of the phyllodes tumors from a tertiary hospital.","authors":"Fatih Dal, Semiha Battal Havare","doi":"10.1590/1806-9282.20240833","DOIUrl":"10.1590/1806-9282.20240833","url":null,"abstract":"<p><strong>Objective: </strong>Phyllodes tumors in the breast are exceptionally uncommon fibroepithelial tumors. In the literature, they are typically categorized as benign phyllodes tumor, borderline phyllodes tumor, and malignant phyllodes tumor. This study aims to assess and present the clinical and surgical outcomes of patients diagnosed with phyllodes tumor.</p><p><strong>Methods: </strong>The outcomes of patients aged 18 years and above diagnosed with phyllodes tumor between 2006 and 2023 were retrospectively reviewed. Patients were grouped as benign phyllodes tumor and borderline/malignant phyllodes tumor and compared by clinical and surgical results.</p><p><strong>Results: </strong>Of all 57 patients with phyllodes tumor, 64.9% (n=37) were benign phyllodes tumor and 35.1% (n=20) were borderline/malignant phyllodes tumor [22.8% (n=13) borderline phyllodes tumor and 12.3% (n=7) malignant phyllodes tumor]. When the patients were divided into two groups as benign phyllodes tumor and borderline/malignant phyllodes tumor and compared, our cumulative (total) recurrence rate was 14.0%, with final surgical margin width between groups [(0<final surgical margin<2 mm vs final surgical margin≥2 mm) (p=0.154)] and recurrence [(8.1% benign phyllodes tumor vs 25.0% borderline/malignant phyllodes tumor) (p=0.080)]; there was no significant difference between our rates.</p><p><strong>Conclusion: </strong>Phyllodes tumors of the breast can be followed up with a narrow negative surgical margin (0 mm<final surgical margin<2 mm). However, after the initial surgery, re-excision is recommended for positive margins, while a wider surgical margin (≥10 mm) is not necessary for excision.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240833"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of genital self-image on sexual satisfaction and stress in women after vaginal delivery.","authors":"Tuğçe Sönmez, Özlem Koç, Emine Alver","doi":"10.1590/1806-9282.20240692","DOIUrl":"10.1590/1806-9282.20240692","url":null,"abstract":"<p><strong>Objective: </strong>Pregnancy, childbirth, and postpartum periods bring along biological, psychological, and social changes that could affect women's sexual health. The aim of this study was to evaluate the effect of genital self-image on sexual satisfaction and stress in women who had a vaginal delivery.</p><p><strong>Methods: </strong>This descriptive and cross-sectional study was conducted online between June and September 2023 by using snowball sampling and the data collection forms prepared in the GoogleDocs program. Women who had a normal vaginal delivery were included, were within 6 weeks to 1 year postpartum, were able to use at least one of the social media networks (e-mail, WhatsApp, Facebook, and Instagram), and volunteered to participate in the research. Data were collected through the Personal Information Form, the \"Female Genital Self-Image Scale,\" the \"Golombok-Rust Inventory of Sexual Satisfaction,\" and the \"Female Sexual Distress Scale-Revised.\"</p><p><strong>Results: </strong>The average age of the participating women was 30.54±5.83 years (n=235). The participants' mean scores were 18.94±2.92 for the Female Genital Self-Image Scale, 40.07±15.51 for the Golombok-Rust Inventory of Sexual Satisfaction, and 8.85±8.50 for the Female Sexual Distress Scale-Revised total. A statistically significant and negative relationship was found between Female Genital Self-Image Scale and Golombok-Rust Inventory of Sexual Satisfaction and Female Sexual Distress Scale-Revised total scores (r=-0.183, p<0.01; r=-0.387, p<0.01). Regression analysis (forward) was performed, and genital self-image was found to be the predictive factor affecting sexual satisfaction and stress.</p><p><strong>Conclusion: </strong>This study found that women had a medium level of genital self-image and sexual satisfaction and a low level of sexual distress.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240692"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of serum Metrnl levels in pregnant women with gestational diabetes mellitus: a prospective non-interventional cohort study.","authors":"Sabina Damirova, İbrahim Kale, Ayşegül Özel, Ayşe Keleş, Cem Yalçınkaya, Murat Muhcu","doi":"10.1590/1806-9282.20240660","DOIUrl":"10.1590/1806-9282.20240660","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to investigate serum Metrnl levels in pregnant women with gestational diabetes mellitus and compare them with pregnant women without gestational diabetes mellitus.</p><p><strong>Methods: </strong>The gestational diabetes mellitus group consisted of 87 pregnant women diagnosed with gestational diabetes mellitus, and the control group consisted of 93 healthy pregnant women without gestational diabetes mellitus. Serum Metrnl levels were determined by the enzyme-linked immunosorbent assay method.</p><p><strong>Results: </strong>The two groups were similar in terms of demographic features. The median serum Metrnl level was found to be 1.16 ng/mL in the gestational diabetes mellitus group, while it was determined as 2.2 ng/mL in the control group (p=0.001). The two groups were divided into two subgroups based on participants' body mass index, normal weight and overweight. The lowest median Metrnl level was detected in the normal weight gestational diabetes mellitus group, followed by the overweight gestational diabetes mellitus group, normal weight control group, and overweight control group (1.1, 1.2, 2, and 2.4 ng/mL, respectively). Receiver operating curve analysis was performed to determine the value of the serum Metrnl level in terms of predicting gestational diabetes mellitus. The area under the curve analysis of serum Metrnl for gestational diabetes mellitus estimation was 0.768 (p=0.000, 95%CI 0.698-0.839). The optimal cutoff value for serum Metrnl level was determined as 1.53 ng/mL with 69% sensitivity and 70% specificity.</p><p><strong>Conclusion: </strong>Serum Metrnl levels in pregnant women with gestational diabetes mellitus were found to be significantly lower than in pregnant women without gestational diabetes mellitus. The mechanisms underlying the decrease in serum Metrnl levels in gestational diabetes mellitus remain unclear for now, and future studies will reveal the role of Metrnl in the pathophysiology of gestational diabetes mellitus.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240660"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum glucose-potassium ratio predicts inhospital mortality in patients admitted to coronary care unit.","authors":"Fulya Avcı Demir, İbrahim Ersoy, Ahmet Şeyda Yılmaz, Gökay Taylan, Emin Erdem Kaya, Ertan Aydın, Muammer Karakayalı, Muhammed Mürsel Öğütveren, Aybike Taşdelen Acar, Şıho Hidayet","doi":"10.1590/1806-9282.20240508","DOIUrl":"10.1590/1806-9282.20240508","url":null,"abstract":"<p><strong>Objective: </strong>The aim of our study was to determine the role of serum glucose-potassium ratio in predicting inhospital mortality in coronary care unit patients.</p><p><strong>Methods: </strong>This study used data from the MORtality in CORonary Care Units in Turkey study, a national, observational, multicenter study that included all patients admitted to coronary care units between September 1, 2022, and September 30, 2022. Statistical analyses assessed the independent predictors of mortality. Two models were created. Model 1 included age, history of heart failure, chronic kidney disease, hypertension, diabetes mellitus, and coronary artery disease. Model 2 included glucose-potassium ratio in addition to these variables. Multivariate regression and receiver operating characteristic analysis were performed to compare Model 1 and Model 2 to identify if the glucose-potassium ratio is an independent predictor of inhospital mortality.</p><p><strong>Results: </strong>In a study of 3,157 patients, the mortality rate was 4.3% (n=137). Age (p=0.002), female gender (p=0.004), mean blood pressure (p<0.001), serum creatinine (p<0.001), C-reactive protein (p=0.002), white blood cell (p=0.002), and glucose-potassium ratio (p<0.001) were identified as independent predictors of mortality through multivariate regression analysis. The receiver operating characteristic analysis indicated that Model 2 had a statistically higher area under the curve than Model 1 (area under the curve 0.842 vs area under the curve 0.835; p<0.001). A statistically significant correlation was found between the inhospital mortality and glucose-potassium ratio (OR 1.015, 95%CI 1.006-1.024, p<0.001).</p><p><strong>Conclusion: </strong>Our study showed that the glucose-potassium ratio may be a significant predictor of inhospital mortality in coronary care unit patients.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240508"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of relaxation exercises on fatigue in hemodialysis patients: a meta-analysis study.","authors":"Ayşegül Yıldız İçigen, Emine Erdem","doi":"10.1590/1806-9282.20240680","DOIUrl":"10.1590/1806-9282.20240680","url":null,"abstract":"<p><strong>Objective: </strong>This study was conducted to determine the effect of relaxation exercise on fatigue symptoms in hemodialysis patients.</p><p><strong>Methods: </strong>This is a meta-analysis study. The literature review was carried out by searching studies published between 2011 and 2020. This meta-analysis was recorded on PROSPERO in the National Health Research Institute (Registration no: CRD42022313646).</p><p><strong>Results: </strong>Seven studies meeting the inclusion criteria were included in the meta-analysis. The effect size of the studies included in the meta-analysis was found to be g=1.232 (p=0.028), which indicated a \"huge effect size.\" The scale used in the subgroup analyses, the application time of the relaxation exercise, and the number of relaxation exercise applications were evaluated, and a significant difference was found at p<0.05.</p><p><strong>Conclusion: </strong>Relaxation exercises can be used as an effective method for reducing fatigue in hemodialysis patients.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240680"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in the evaluation of HER2 and HER2-low in breast cancer in Brazil and recommendations of a multidisciplinary working group.","authors":"Helenice Gobbi, Filomena Marino Carvalho, Marina De Brot, Angela Flavia Logullo, Carlos Augusto Moreira Silva, Fernando Augusto Soares, Luciana Landeiro, Rosemar Rahal, Carlos Henrique Barrios","doi":"10.1590/1806-9282.20240313","DOIUrl":"10.1590/1806-9282.20240313","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240313"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142368107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of temporomandibular joint dysfunction in patients with ankylosing spondylitis and comparison of the findings with healthy controls.","authors":"Büşra Şirin Ahısha, Fatma Nur Kesiktaş","doi":"10.1590/1806-9282.20240807","DOIUrl":"10.1590/1806-9282.20240807","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the prevalence of temporomandibular dysfunction in ankylosing spondylitis patients and healthy controls, examining the relationship between temporomandibular dysfunction and disease activity in ankylosing spondylitis patients, as well as associations with psychosocial factors.</p><p><strong>Methods: </strong>The study included 113 ankylosing spondylitis patients and 110 healthy individuals aged 18-75. Temporomandibular dysfunction presence was evaluated using Diagnostic Criteria for Temporomandibular Disorders Axis I. Disease activity was assessed with the Bath Ankylosing Spondylitis Disease Activity Index, Bath Ankylosing Spondylitis Metrology Index, and Bath Ankylosing Spondylitis Functional Index.</p><p><strong>Results: </strong>Among healthy individuals, 60.9% did not receive a temporomandibular dysfunction diagnosis, while 39.1% received at least one diagnosis. In contrast, 69.9% of the 113 ankylosing spondylitis patients received at least one temporomandibular dysfunction diagnosis, and only 30.1% were not included in any diagnosis group (p<0.001). Joint (p=0.001) and pain disorders (p=0.008) were significantly more common in the ankylosing spondylitis group than in the healthy controls. Significant associations emerged between Bath Ankylosing Spondylitis Disease Activity Index (p<0.001) and Bath Ankylosing Spondylitis Functional Index (p=0.005) scores and pain disorders.</p><p><strong>Conclusion: </strong>Temporomandibular dysfunction is more prevalent in ankylosing spondylitis patients than in healthy individuals, linked to increased joint issues and pain associated with disease activity.</p><p><strong>Clinicaltrials.gov id: </strong>NCT05839925.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240807"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142368127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of first-trimester systemic immune-inflammation index for the prediction of gestational diabetes mellitus.","authors":"Nizamettin Bozbay, Anara Medinaeva, Fikret Akyürek, Gokcen Orgul","doi":"10.1590/1806-9282.20240532","DOIUrl":"10.1590/1806-9282.20240532","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the role of systemic immune-inflammation index, neutrophil-lymphocyte ratio, lymphocyte-monocyte ratio, and platelet-lymphocyte ratios calculated in the first trimester as inflammatory markers in predicting gestational diabetes mellitus diagnosis.</p><p><strong>Methods: </strong>This study was conducted retrospectively at a tertiary center between January 2020 and June 2023. A total of 111 pregnant women with gestational diabetes and 378 pregnant women in the control group were included in the study. Systemic immune-inflammation index, neutrophil-lymphocyte ratio, lymphocyte-monocyte ratio, and platelet-lymphocyte ratios values were compared between the gestational diabetes mellitus group patients and the healthy group. Receiver operating characteristic analysis curve was used for predicting gestational diabetes mellitus using systemic immune-inflammation index and lymphocyte-monocyte ratio.</p><p><strong>Results: </strong>In pregnant women in the first trimester, systemic immune-inflammation index and lymphocyte-monocyte ratio values based on routine complete blood count parameters were found to be statistically significantly higher in gestational diabetes mellitus patients compared to healthy patients, while neutrophil-lymphocyte ratio and platelet-lymphocyte ratios values were found to be similar (p=0.033, p=0.005, p=0.211, and p=0.989). For predicting gestational diabetes mellitus, a cut-off value of 655.75 for systemic immune-inflammation index resulted in 80.2% sensitivity and 34.4% specificity, and a cut-off value of 3.62 for lymphocyte-monocyte ratio resulted in 56.8% sensitivity and 63.2% specificity, indicating good discriminatory ability.</p><p><strong>Conclusion: </strong>We believe that systemic immune-inflammation index and lymphocyte-monocyte ratio values measured in the first-trimester complete blood count parameters are effective in predicting gestational diabetes mellitus but are not effective in determining insulin requirement.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240532"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142368131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fear, anxiety, and knowledge levels of women who underwent gynecologic surgery during the COVID-19 pandemic.","authors":"Mehmet Ferdi Kıncı, İlknur Yeşilçınar, Gülten Güvenç, Hikmet Can Ünver, Ahmet Akın Sivaslıoğlu","doi":"10.1590/1806-9282.20240422","DOIUrl":"10.1590/1806-9282.20240422","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to evaluate the fear, anxiety, and knowledge level in women who underwent gynecological surgical procedures during the COVID-19 pandemic.</p><p><strong>Methods: </strong>This cross-sectional study was conducted on 188 women who underwent a gynecologic surgical operation in Muğla, Turkey. Data were collected by using demographics and obstetric detail form, questionnaire on knowledge, attitudes, and practice toward COVID-19, and State-Trait Anxiety Inventory-I (STAI-I).</p><p><strong>Results: </strong>Most of the women perceived their surgical process as very urgent. Women felt fear mostly for being infected with the virus, and they were afraid of transmitting COVID-19 to another one. The COVID-19 knowledge scores of women who had undergone cancer surgery were statistically significantly higher than others (p=0.017). The STAI-I scores of women increased as their COVID-19 knowledge scores increased (p<0.05).</p><p><strong>Conclusion: </strong>This study demonstrated that women were afraid of COVID-19 infection during gynecological operation and due to hospitalization, sociodemographic characteristics affected the knowledge levels about COVID-19 infection, and the anxiety levels of the women. Planning appropriate interventions to decrease the fear and anxiety of women who undergo gynecological surgery during the pandemic is important to ensure that women adhere to their treatment and follow-up in the postoperative period.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 10","pages":"e20240422"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142368108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}