Revista da Associacao Medica Brasileira (1992)最新文献

{"title":"Assessment of osteoporosis awareness and knowledge levels in people living with HIV.","authors":"Burak Sarikaya, Mustafa Hüseyin Temel, Emre Ata, Vahibe Aydin Sarikaya, Rıza Aytaç Çetinkaya","doi":"10.1590/1806-9282.20240925","DOIUrl":"10.1590/1806-9282.20240925","url":null,"abstract":"<p><strong>Objective: </strong>Human immunodeficiency virus is associated with an increased risk of osteopenia and osteoporosis through multiple complex mechanisms. With an increased awareness on this issue, patients can avoid the preventable causes of osteoporosis. The aim of this study was to assess the awareness and knowledge regarding osteoporosis among people living with HIV (PLWH).</p><p><strong>Methods: </strong>A total of 329 PLWH agreed to participate in the study. The patients completed a Google Forms questionnaire consisting of three sections. The first section included binary (yes/no) questions to assess participants' awareness of osteoporosis, knowledge about the condition, perceived susceptibility, and understanding of potential complications. The second section employed the Osteoporosis Awareness Scale, while the third section employed the Revised Osteoporosis Knowledge Tool.</p><p><strong>Results: </strong>The average age of the 329 patients was 40.21±12.4 years, and 89.4% were male. The mean scores were 66.97±20.68 on the Osteoporosis Awareness Scale and 16.34±6.37 on the Revised Osteoporosis Knowledge Tool. When asked whether they were familiar with osteoporosis, 53.2% of the participants responded yes. Notably, 40% of the participants had knowledge about osteoporosis and its complications, with 50.8% believing that osteoporosis is a serious condition that can be life-threatening. Osteoporosis awareness increased proportionally with the level of education (p<0.001). Patients with a pre-treatment CD4 count<200/mm³ had significantly lower levels of both osteoporosis awareness and knowledge (p<0.001).</p><p><strong>Conclusion: </strong>This study revealed that PLWH have insufficient knowledge and low awareness regarding osteoporosis. In particular, patients with a pre-treatment CD4 count<200/mm³ and those with lower education levels were found to have the lowest awareness level of osteoporosis.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 1","pages":"e20240925"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The left venous anatomy of the female pelvis and clinical outcomes: new insights.","authors":"Marcos de Lorenzo Messina, Ricardo Dos Santos Simões, Maria Cândida Pinheiro Baracat, José Maria Soares Júnior, Edmund Chada Baracat","doi":"10.1590/1806-9282.0711EDIT","DOIUrl":"10.1590/1806-9282.0711EDIT","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 1","pages":"e0711EDIT"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multisequence combined magnetic resonance imaging radiomics model to noninvasively predict nuclear grade of clear cell renal cell carcinoma: interpretable model development.","authors":"Esat Kaba, Hande Melike Bülbül, Mehmet Kıvrak, Nur Hürsoy","doi":"10.1590/1806-9282.20241012","DOIUrl":"10.1590/1806-9282.20241012","url":null,"abstract":"<p><strong>Objective: </strong>The nuclear grade of clear cell renal cell carcinoma directly relates to prognosis and is usually determined through invasive methods like biopsy or surgery. This study aimed to predict the nuclear grade of clear cell renal cell carcinoma using a noninvasive method: multisequence magnetic resonance imaging-based radiomics analysis.</p><p><strong>Methods: </strong>A total of 42 clear cell renal cell carcinomas (29 low grade, 13 high grade) were included in the study. T2, fat-suppressed T2, noncontrast T1, corticomedullary phase, nephrographic phase, excretory phase, and apparent diffusion coefficient sequences of patients were used for radiomics analysis. Inter-observer agreement was assessed for these sequences, and following reproducibility analysis and feature selection, three new groups were formed: noncontrast enhancement, contrast enhancement, and combined groups, with different combinations of features extracted from these sequences. As a result, seven different sequences and three different groups constituted 10 classification groups. An extreme gradient boosting model was used for classification, employing 10-fold cross-validation.</p><p><strong>Results: </strong>Radiomics features from corticomedullary phase and nephrographic phase sequences showed excellent inter-observer agreement, with Pearson correlation coefficient values of 0.88 for corticomedullary phase and 0.90 for nephrographic phase. The study included 42 clear cell renal cell carcinomas with a mean age of 60.8 years. Individually, the corticomedullary phase sequence achieved the highest area under the curve and accuracy values (0.88 and 0.85), followed by the apparent diffusion coefficient sequence (0.87 and 0.79). In the combined sequence group, the contrast enhancement group showed the highest area under the curve and accuracy (0.93 and 0.87), ranking highest across the entire study.</p><p><strong>Conclusion: </strong>Multisequence magnetic resonance imaging radiomics has great potential to predict the nuclear grade of clear cell renal cell carcinoma and guide the treatment plan noninvasively.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 1","pages":"e20241012"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pelvic endometriosis: epidemiological and clinical profile prior to surgical treatment.","authors":"Danielle Costa Nazareth, Daniel Bier Caraça, Gabriela Guimarães Franco Ramos, Sergio Podgaec","doi":"10.1590/1806-9282.20240746","DOIUrl":"10.1590/1806-9282.20240746","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to analyze the epidemiological, sociodemographic, and clinical profile of women undergoing videolaparoscopic surgery for the treatment of pelvic endometriosis at the Hospital Israelita Albert Einstein.</p><p><strong>Methods: </strong>A cross-sectional and descriptive study was conducted, including 110 patients who underwent surgery for endometriosis between January 2017 and December 2022. Sociodemographic information, personal history, symptomatology, radiological diagnosis, and surgical details were collected.</p><p><strong>Results: </strong>The average age of the evaluated patients was 37.04 years. Most were white women (69.7%), married or in a stable union (57.8%), and had completed secondary or higher education (86.3%). Dysmenorrhea was the predominant complaint in 60% of cases, with symptom onset occurring mainly between 1 and 5 years (48.2% of the total). Postoperative complications were observed in 8.1% of participants (9 cases), while the main associated comorbidities were anxiety and depression, represented in 43.3% of cases (26 cases).</p><p><strong>Conclusion: </strong>Endometriosis presents as a condition that negatively impacts women's quality of life, generally diagnosed between the fourth and fifth decades of life. Hormonal treatment is sometimes insufficient to resolve symptoms, requiring surgical intervention for clinical improvement.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 1","pages":"e20240746"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of omega-3 fatty acid use on women's mental health in postpartum depression: a systematic review and meta-analysis study.","authors":"Sevda Karakaş, Sevda Uzun, Handan Özcan","doi":"10.1590/1806-9282.20241389","DOIUrl":"10.1590/1806-9282.20241389","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 1","pages":"e20241389"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can aspartate aminotransferase and platelet distribution width-to-platelet ratio in the first trimester predict fetal macrosomia?: a retrospective case-control study.","authors":"Fahri Burcin Firatligil, Arife Akay, Merve Ugur, Sadun Sucu, Yıldız Akdas Reis, Serap Topkara Sucu, Yaprak Engin-Ustun","doi":"10.1590/1806-9282.20240919","DOIUrl":"10.1590/1806-9282.20240919","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the performance of aspartate aminotransferase level and platelet distribution width-to-platelet ratio as predictive factors for fetal macrosomia in the first trimester.</p><p><strong>Methods: </strong>This retrospective case-control study was conducted between August 2017 and August 2020. The data of the study group as Group I (n=426) and the control group as Group II (n=426) were collected and compared by scanning the records. For each patient who was eligible for Group I, the first patient from the file review who met the criteria listed in the inclusion/exclusion section was selected for Group II. Aspartate aminotransferase levels and serum platelet distribution width-to-platelet ratio levels were determined in the first trimester using the participants' medical records. The study parameters of the two groups were statistically compared.</p><p><strong>Results: </strong>The median aspartate aminotransferase, platelet, platelet distribution width, and platelet distribution width-to-platelet ratio values of the laboratory test results in the first trimester were significantly different. The aspartate aminotransferase and platelet distribution width-to-platelet ratio values were higher in Group I.</p><p><strong>Conclusion: </strong>Higher aspartate aminotransferase and platelet distribution width-to-platelet ratio levels in the maternal blood sample in the first trimester indicate an unbalanced inflammatory process causing fetal macrosomia. The cutoff values for aspartate aminotransferase (>21 U/L) at 94% specificity and for platelet distribution width-to-platelet ratio (>0.19) at 51% specificity can be used as markers for a screening test. However, randomized controlled trials combining body mass index and the parameters in the present study are needed in future studies.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 1","pages":"e20240919"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Molecular monitoring by CDKN2A/p16INK4A and RB1 gene methylation in breast cancer\".","authors":"Huaxiao Tang, Lianlian Song","doi":"10.1590/1806-9282.20241031","DOIUrl":"10.1590/1806-9282.20241031","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 1","pages":"e20241031"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11918829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1590/1806-9282.20240943ERRATUM","DOIUrl":"10.1590/1806-9282.20240943ERRATUM","url":null,"abstract":"<p><p>[This corrects the article doi: 10.1590/1806-9282.20240943].</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 1","pages":"e20240943"},"PeriodicalIF":0.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11809560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1590/1806-9282.20240888ERRATUM","DOIUrl":"10.1590/1806-9282.20240888ERRATUM","url":null,"abstract":"<p><p>[This corrects the article doi: 10.1590/1806-9282.20240888].</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 1","pages":"e20240888ERRATUM"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143026220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of long-term negative energy on appetite hormone levels in individuals with prediabetes and diabetes.","authors":"Gülşah Alyar, Fatma Zuhal Umudum, Neslihan Yüce, Nergis Akbaş","doi":"10.1590/1806-9282.20240897","DOIUrl":"https://doi.org/10.1590/1806-9282.20240897","url":null,"abstract":"<p><strong>Objective: </strong>Calorie restriction and exercise are commonly used first interventions to prevent the progression of prediabetes and alleviate the symptoms of type 2 diabetes. Our study was designed to determine the effect of the energy deficit caused by long-term (12-week) calorie restriction and exercise programs on appetite responses in obese individuals with prediabetes and type 2 diabetes.</p><p><strong>Methods: </strong>Calorie restriction and exercise programs appropriate for age, gender, and work environment were applied to 22 individuals with prediabetes and 22 with type 2 diabetes participating in the study for a period of 12 weeks. Ghrelin, glucagon-like peptide-1, and peptide tyrosine tyrosine values of samples taken before and after treatment were determined by the enzyme-linked ιmmunosorbent assay method.</p><p><strong>Results: </strong>Appetite hormone levels did not change after calorie restriction and exercise in the prediabetes group (p>0.05). In the diabetes group, calorie restriction and exercise significantly increased ghrelin and peptide tyrosine tyrosine concentrations (p<0.005). Additionally, when all patients were evaluated together, ghrelin, glucagon-like peptide-1 and peptide tyrosine tyrosine levels differed significantly after the intervention (p<0.005).</p><p><strong>Conclusion: </strong>The energy deficit created by long-term calorie restriction and exercise did not modulate the appetite hormones in prediabetic and obese individuals. However, increased ghrelin and peptide tyrosine tyrosine levels in individuals with diabetes support that the same treatment program is an effective method to regulate appetite hormones.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 1","pages":"e20240897"},"PeriodicalIF":0.0,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}